Acupuncture needling sensation: The neural correlates of deqi using fMRI

Brain Research

Volumn 1315, Issue , 2010, Pages 111-118

  Asghar, Aziz UR ^a,b   Green, Gary ^a   Lythgoe, Mark F ^c   Lewith, George ^d   MacPherson, Hugh ^a  

^a UNIVERSITY OF YORK   (United Kingdom)

^b UNIVERSITY OF HULL   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

Acupuncture; Functional magnetic resonance imaging; Needling sensation

Indexed keywords

ACUPUNCTURE; ADULT; ARTICLE; BRAIN REGION; CEREBELLUM; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; HUMAN EXPERIMENT; MALE; NEEDLE; NEUROIMAGING; NOCICEPTION; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OXYGEN BLOOD LEVEL; PRIORITY JOURNAL; RIGHT HANDEDNESS; SENSATION;

ACUPUNCTURE THERAPY; ADULT; BRAIN; BRAIN MAPPING; CEREBROVASCULAR CIRCULATION; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NEEDLES; OXYGEN; PAIN; PAIN MEASUREMENT; PSYCHOPHYSICS; SENSATION; YOUNG ADULT;

EID: 75349083076     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2009.12.019     Document Type: Article

References (36)

1. Beckmann C.F., Jenkinson M., and Smith S.M. General multilevel linear modeling for group analysis in FMRI. NeuroImage 20 (2003) 1052-1063
2. Biella G., Sotgiu M.L., Pellegata G., Paulesu E., Castiglioni I., and Fazio F. Acupuncture produces central activations in pain regions. NeuroImage 14 (2001) 60-66
3. Birch S., and Felt R. Understanding Acupuncture (1999), Churchill Livingstone, Edinburgh
4. Bovey M. De Qi. J. Chin. Med. 81 (2006) 18-29
5. Chiang C.Y., Chang C.T., Chu H.L., and Yang I.L. Peripheral afferent pathway for acupuncture analgesia. Sci. Sin. 16 (1973) 210-217
6. Davis K.D. The neural circuitry of pain as explored with functional MRI. Neurol. Res. 22 (2000) 313-317
7. Deadman P., and Al-Khafaji M. A manual of acupuncture. J. Chin. Med. Publications (1998)
8. Fang J., Jin Z., Wang Y., Li K., Kong J., Nixon E.E., Zeng Y., Ren Y., Tong H., Wang Y., Wang P., and Hui K.K. The salient characteristics of the central effects of acupuncture needling: limbic-paralimbic-neocortical network modulation. Hum. Brain Mapp. 30 (2009) 1196-1206
9. Fang J.L., Krings T., Weidemann J., Meister I.G., and Thron A. Functional MRI in healthy subjects during acupuncture: different effects of needle rotation in real and false acupoints. Neuroradiology 46 (2004) 359-362
10. Han J.S. Acupuncture and endorphins. Neurosci. Lett. 361 1-3 (2004) 258-261
11. Hsieh J.C., Tu C.H., Chen F.P., Chen M.C., Yeh T.C., Cheng H.C., Wu Y.T., Liu R.S., and Ho L.T. Activation of the hypothalamus characterizes the acupuncture stimulation at the analgesic point in human: a positron emission tomography study. Neurosci. Lett. 307 (2001) 105-108
12. Hui K.K., Liu J., Makris N., Gollub R.L., Chen A.J., Moore C.I., Kennedy D.N., Rosen B.R., and Kwong K.K. Acupuncture modulates the limbic system and subcortical gray structures of the human brain: evidence from fMRI studies in normal subjects. Hum. Brain Mapp. 9 (2000) 13-25
13. Hui K.K., Liu J., Marina O., Napadow V., Haselgrove C., Kwong K.K., Kennedy D.N., and Makris N. The integrated response of the human cerebro-cerebellar and limbic systems to acupuncture stimulation at ST 36 as evidenced by fMRI. NeuroImage 27 (2005) 479-496
14. Hui K.K., Nixon E.E., Vangel M.G., Liu J., Marina O., Napadow V., Hodge S.M., Rosen B.R., Makris N., and Kennedy D.N. Characterization of the "deqi" response in acupuncture. BMC Complement. Altern. Med. 7 (2007) 33
15. Jenkinson M., and Smith S. A global optimisation method for robust affine registration of brain images. Med. Image Anal. 5 (2001) 143-156
16. Jenkinson M., Bannister P., Brady M., and Smith S. Improved optimization for the robust and accurate linear registration and motion correction of brain images. NeuroImage 17 (2002) 825-841
17. Kong J., Fufa D.T., Gerber A.J., Rosman I.S., Vangel M.G., Gracely R.H., and Gollub R.L. Psychophysical outcomes from a randomized pilot study of manual, electro, and sham acupuncture treatment on experimentally induced thermal pain. J. Pain 6 (2005) 55-64
18. Kong J., Gollub R., Huang T., Polich G., Napadow V., Hui K., Vangel M., Rosen B., and Kaptchuk T.J. Acupuncture de qi, from qualitative history to quantitative measurement. J. Altern. Complement. Med. 13 (2007) 1059-1070
19. Lewith G.T., White P.J., and Pariente J. Investigating acupuncture using brain imaging techniques: the current state of play. Evid. Based Complement. Altern. Med. 2 (2005) 315-319
20. MacPherson H., and Asghar A. Acupuncture needle sensations associated with de qi: a classification based on experts' ratings. J. Altern. Complement. Med. 12 (2006) 633-637
21. MacPherson H., Thomas K., Walters S., and Fitter M. A prospective survey of adverse events and treatment reactions following 34,000 consultations with professional acupuncturists. Acupunct. Med. 19 (2001) 93-102
22. MacPherson H., Green G., Nevado A., Lythgoe M.F., Lewith G., Devlin R., Haselfoot R., and Asghar A.U. Brain imaging of acupuncture: comparing superficial with deep needling. Neurosci. Lett. 434 (2008) 144-149
23. Melzack R. McGill pain questionnaire: major properties and scoring methods. Pain 1 (1975) 275-299
24. Park J., White A., Stevinson C., Ernst E., and James M. Validating a new non-penetrating sham acupuncture device: two randomised controlled trials. Acupunct. Med. 20 (2002) 168-174
25. Price D.D. Psychological and neural mechanisms of the affective dimension of pain. Science 288 (2000) 1769-1772
26. Takeda W., and Wessel J. Acupuncture for the treatment of pain of osteoarthritic knees. Arthritis Care Res. 7 (1994) 118-122
27. Thomas K.J., MacPherson H., Thorpe L., Brazier J., Fitter M., Campbell M.J., Roman M., Walters S.J., and Nicholl J. Randomised controlled trial of a short course of traditional acupuncture compared with usual care for persistent non-specific low back pain. BMJ 333 (2006) 623-626
28. Vincent C.A., Richardson P.H., Black J.J., and Pither C.E. The significance of needle placement site in acupuncture. J. Psychosom. Res. 33 (1989) 489-496
29. Wager T.D., Rilling J.K., Smith E.E., Sokolik A., Casey K.L., Davidson R.J., Kosslyn S.M., Rose R.M., and Cohen J.D. Placebo-induced changes in FMRI in the anticipation and experience of pain. Science 303 (2004) 1162-1167
30. White P., Bishop F., Hardy H., Abdollahian S., White A., Park J., Kaptchuk T.J., and Lewith G.T. Southampton Needle Sensation Questionnaire: development and validation of a measure to gauge acupuncture needle sensation. J. Altern. Complement. Med. 14 (2008) 373-379
31. Woolrich M.W., Ripley B.D., Brady M., and Smith S.M. Temporal autocorrelation in univariate linear modeling of FMRI data. NeuroImage 14 (2001) 1370-1386
32. Woolrich M.W., Behrens T.E., and Smith S.M. Constrained linear basis sets for HRF modelling using Variational Bayes. NeuroImage 21 (2004) 1748-1761
33. Worsley K.J., Evans A.C., Marrett S., and Neelin P. A three-dimensional statistical analysis for CBF activation studies in human brain. J. Cereb. Blood Flow Metab. 12 (1992) 900-918
34. Wu M.T., Hsieh J.C., Xiong J., Yang C.F., Pan H.B., Chen Y.C., Tsai G., Rosen B.R., and Kwong K.K. Central nervous pathway for acupuncture stimulation: localization of processing with functional MR imaging of the brain-preliminary experience. Radiology 212 (1999) 133-141
35. Yan B., Li K., Xu J., Wang W., Li K., Liu H., Shan B., and Tang X. Acupoint-specific fMRI patterns in human brain. Neurosci. Lett. 383 (2005) 236-240
36. Yoo S.S., Teh E.K., Blinder R.A., and Jolesz F.A. Modulation of cerebellar activities by acupuncture stimulation: evidence from fMRI study. NeuroImage 22 (2004) 932-940