The ethics of two- and one-sided hypothesis tests for clinical trials

Clinical Ethics

Volumn 2, Issue 2, 2007, Pages 100-102

  Owen, A ^a  

^a KENT AND CANTERBURY HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 75249092659     PISSN: 14777509     EISSN: None     Source Type: Journal    
DOI: 10.1258/147775007781029537     Document Type: Article

References (13)

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6. Peace KE. One-sided or two-sided p values: Which most appropriately address the question of drug efficacy? J Biopharm Stats 1991;1:133-8
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13. The CAST Investigators. Preliminary report: effect of encainide and flecainide on mortality in a randomized trial of arrhythmia suppression after myocardial infarction. N Engl J Med 1989;321:406-12