Synthesis of 2,3-disubstituted pyrazines and quinoxalines by Heck cross-coupling reactions of 2,3-dichloropyrazine and 2,3-dichloroquinoxaline. Influence of the temperature on the product distribution

Tetrahedron

Volumn 66, Issue 9, 2010, Pages 1637-1642

  Malik, Imran ^a   Hussain, Munawar ^a   Ali, Asad ^a   Tengho Toguem, Serge Mithérand ^a   Basha, Fatima Z ^b   Fischer, Christine ^c   Langer, Peter ^a,c  

^a UNIVERSITY OF ROSTOCK   (Germany)

^b UNIVERSITY OF KARACHI   (Pakistan)

^c LEIBNIZ INSTITUT FÜR KATALYSE E V AN DER UNIVERSITÄT ROSTOCK   (Germany)

Author keywords

Catalysis; Cross coupling reactions; Palladium; Pyrazine

Indexed keywords

(2E,2'E) DIETHYL 3,3' (PYRAZINE 2,3 DIYL)DIACRYLATE; (E) 2 (2 CYCLOHEXYLVINYL)QUINOXALINE; (E) 2 ETHYLHEXYL 3 [3 [3 (2 ETHYLHEXYLOXY) 3 OXOPROPYL]PYRAZIN 2 YL]ACRYLATE; (E) BUTYL 3 [3 (3 BUTOXY 3 OXOPROPYL)PYRAZIN 2 YL]ACRYLATE; (E) ETHYL 3 [3 (3 ETHOXY 3 OXOPROPYL)PYRAZIN 2 YL]ACRYLATE; (E) HEXYL 3 [3 (3 (HEXYLOXY) 3 OXOPROPYL)PYRAZIN 2 YL]ACRYLATE; (E) ISOBUTYL 3 [3 (3 ISOBUTOXY 3 OXOPROPYL)PYRAZIN 2 YL] ACRYLATE; (E) METHYL 3 [3 (3 METHOXY 3 OXOPROPYL)PYRAZIN 2 YL]ACRYLATE; (E) TERT BUTYL 3 [3 (3 TERT BUTOXY 3 OXOPROPYL) QUINOXALIN 2 YL] ACRYLATE; (E) TERT BUTYL 3 [3 (3 TERT BUTOXY 3 OXOPROPYL)PYRAZIN 2 YL]ACRYLATE; 2,3 BIS (4 TERT BUTOXYSTYRYL)QUINOXALINE; 2,3 BIS(4 CHLOROSTYRYL)PYRAZINE; 2,3 BIS(4 METHOXYSTYRYL)PYRAZINE; 2,3 BIS(4 METHOXYSTYRYL)QUINOXALINE; 2,3 BIS(4 METHYLSTYRYL)PYRAZINE; 2,3 BIS(4 TERT BUTOXYSTYRYL)PYRAZINE; 2,3 BIS(4 TERT BUTYLSTYRYL)QUINOXALINE; 2,3 BIS(E 2 CYCLOHEXYLVINYL)QUINOXALINE; 2,3 DISTYRYLPYRAZINE; 2,3 DISTYRYLQUINOXALINE; BIS(2 ETHYLHEXYL) 3,3' (QUINOXALINE 2,3 DIYL) DIPROPANOATE; DIBUTYL 3,3' (PYRAZINE 2,3 DIYL)DIPROPANOATE; DIMETHYL 3,3' (QUINOXALINE 2,3 DIYL)DIACRYLATE; ISOBUTYL 3,3' (PYRAZINE 2,3 DIYL)DIPROPANOATE; PYRAZINE DERIVATIVE; QUINOXALINE DERIVATIVE; TERT BUTYL 3,3' (PYRAZINE 2,3 DIYL)DIPROPANOATE; TERT BUTYL 3,3' (QUINOXALINE 2,3 DIYL)DIPROPANOATE; UNCLASSIFIED DRUG;

ARTICLE; CROSS COUPLING REACTION; DRUG SYNTHESIS; HECK REACTION; PRIORITY JOURNAL; TEMPERATURE SENSITIVITY;

EID: 75149196743     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2010.01.021     Document Type: Article

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