-
2
-
-
0036699940
-
Molecular pathogenesis of human hepatocellular carcinoma
-
Thorgeirsson SS and Grisham JW: Molecular pathogenesis of human hepatocellular carcinoma. Nat Genet 31: 339-346, 2002.
-
(2002)
Nat Genet
, vol.31
, pp. 339-346
-
-
Thorgeirsson, S.S.1
Grisham, J.W.2
-
3
-
-
36549088147
-
CREB3L4, INTS3, and SNAPAP are targets for the 1q21 amplicon frequently detected in hepatocellular carcinoma
-
Inagaki Y, Yasui K, Endo M, Nakajima T, Zen K, Tsuji K, Minami M, Tanaka S, Taniwaki M, Itoh Y, Arii S and Okanoue T: CREB3L4, INTS3, and SNAPAP are targets for the 1q21 amplicon frequently detected in hepatocellular carcinoma. Cancer Genet Cytogenet 180: 30-36, 2008.
-
(2008)
Cancer Genet Cytogenet
, vol.180
, pp. 30-36
-
-
Inagaki, Y.1
Yasui, K.2
Endo, M.3
Nakajima, T.4
Zen, K.5
Tsuji, K.6
Minami, M.7
Tanaka, S.8
Taniwaki, M.9
Itoh, Y.10
Arii, S.11
Okanoue, T.12
-
4
-
-
59949097637
-
ERK5 is a target for gene amplification at 17p11 and promotes cell growth in hepatocellular carcinoma by regulating mitotic entry
-
Zen K, Yasui K, Nakajima T, Zen Y, Zen K, Gen Y, Mitsuyoshi H, Minami M, Mitsufuji S, Tanaka S, Itoh Y, Nakanuma Y, Taniwaki M, Arii S, Okanoue T and Yoshikawa T: ERK5 is a target for gene amplification at 17p11 and promotes cell growth in hepatocellular carcinoma by regulating mitotic entry. Genes Chromosomes Cancer 48: 109-120, 2009.
-
(2009)
Genes Chromosomes Cancer
, vol.48
, pp. 109-120
-
-
Zen, K.1
Yasui, K.2
Nakajima, T.3
Zen, Y.4
Zen, K.5
Gen, Y.6
Mitsuyoshi, H.7
Minami, M.8
Mitsufuji, S.9
Tanaka, S.10
Itoh, Y.11
Nakanuma, Y.12
Taniwaki, M.13
Arii, S.14
Okanoue, T.15
Yoshikawa, T.16
-
5
-
-
58549087779
-
A novel amplification target, ARHGAP5, promotes cell spreading and migration by negatively regulating RhoA in Huh-7 hepatocellular carcinoma cells
-
Gen Y, Yasui K, Zen K, Nakajima T, Tsuji K, Endo M, Mitsuyoshi H, Minami M, Itoh Y, Tanaka S, Taniwaki M, Arii S, Okanoue T and Yoshikawa T: A novel amplification target, ARHGAP5, promotes cell spreading and migration by negatively regulating RhoA in Huh-7 hepatocellular carcinoma cells. Cancer Lett 275: 27-34, 2009.
-
(2009)
Cancer Lett
, vol.275
, pp. 27-34
-
-
Gen, Y.1
Yasui, K.2
Zen, K.3
Nakajima, T.4
Tsuji, K.5
Endo, M.6
Mitsuyoshi, H.7
Minami, M.8
Itoh, Y.9
Tanaka, S.10
Taniwaki, M.11
Arii, S.12
Okanoue, T.13
Yoshikawa, T.14
-
6
-
-
0036098552
-
AP-1 as a regulator of cell life and death
-
Shaulian E and Karin M: AP-1 as a regulator of cell life and death. Nat Cell Biol 4: E131-136, 2002.
-
(2002)
Nat Cell Biol
, vol.4
-
-
Shaulian, E.1
Karin, M.2
-
7
-
-
0035971506
-
Jun, the oncoprotein
-
Vogt PK: Jun, the oncoprotein. Oncogene 20: 2365-2377, 2001.
-
(2001)
Oncogene
, vol.20
, pp. 2365-2377
-
-
Vogt, P.K.1
-
8
-
-
0035971432
-
AP-1 in mouse development and tumorigenesis
-
Jochum W, Passegué E and Wagner EF: AP-1 in mouse development and tumorigenesis. Oncogene 20: 2401-2412, 2001.
-
(2001)
Oncogene
, vol.20
, pp. 2401-2412
-
-
Jochum, W.1
Passegué, E.2
Wagner, E.F.3
-
9
-
-
0023572209
-
Human proto-oncogene c-JUN encodes a DNA-binding protein with structural and functional properties of transcription factor AP-1
-
Bohmann D, Bos TJ, Admon A, Nishimura T, Vogt PK and Tjian R: Human proto-oncogene c-JUN encodes a DNA-binding protein with structural and functional properties of transcription factor AP-1. Science 238: 1386-1392, 1987.
-
(1987)
Science
, vol.238
, pp. 1386-1392
-
-
Bohmann, D.1
Bos, T.J.2
Admon, A.3
Nishimura, T.4
Vogt, P.K.5
Tjian, R.6
-
10
-
-
0023336261
-
Avian sarcoma virus 17 carries the Jun oncogene
-
Maki Y, Bos TJ, Davis C, Starbuck M and Vogt PK: Avian sarcoma virus 17 carries the Jun oncogene. Proc Natl Acad Sci USA 84: 2848-2852, 1987.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 2848-2852
-
-
Maki, Y.1
Bos, T.J.2
Davis, C.3
Starbuck, M.4
Vogt, P.K.5
-
11
-
-
0010638187
-
Deregulated expression of human c-Jun transforms primary rat embryo cells in cooperation with an activated c-Ha-ras gene and transforms rat-la cells as a single gene
-
Schütte J, Minna JD and Birrer MJ: Deregulated expression of human c-Jun transforms primary rat embryo cells in cooperation with an activated c-Ha-ras gene and transforms rat-la cells as a single gene. Proc Natl Acad Sci USA 86: 2257-2261, 1989.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 2257-2261
-
-
Schütte, J.1
Minna, J.D.2
Birrer, M.J.3
-
12
-
-
0028787357
-
c-Fos-induced osteosarcoma formation in transgenic mice: Cooperativity with c-Jun and the role of endogenous c-Fos
-
Wang ZQ, Liang J, Schellander K, Wagner EF and Grigoriadis AE: c-Fos-induced osteosarcoma formation in transgenic mice: cooperativity with c-Jun and the role of endogenous c-Fos. Cancer Res 55: 6244-6251, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 6244-6251
-
-
Wang, Z.Q.1
Liang, J.2
Schellander, K.3
Wagner, E.F.4
Grigoriadis, A.E.5
-
13
-
-
34047161940
-
JUN oncogene amplification and overexpression block adipocytic differentiation in highly aggressive sarcomas
-
Mariani O, Brennetot C, Coindre JM, Gruel N, Ganem C, Delattre O, Stern MH and Aurias A: JUN oncogene amplification and overexpression block adipocytic differentiation in highly aggressive sarcomas. Cancer Cell 11: 361-374, 2007.
-
(2007)
Cancer Cell
, vol.11
, pp. 361-374
-
-
Mariani, O.1
Brennetot, C.2
Coindre, J.M.3
Gruel, N.4
Ganem, C.5
Delattre, O.6
Stern, M.H.7
Aurias, A.8
-
14
-
-
18444369000
-
Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-κB
-
Mathas S, Hinz M, Anagnostopoulos I, Krappmann D, Lietz A, Jundt F, Bommert K, Mechta-Grigoriou F, Stein H, Dörken B and Scheidereit C: Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-κB EMBO J 21: 4104-4113, 2002.
-
(2002)
EMBO J
, vol.21
, pp. 4104-4113
-
-
Mathas, S.1
Hinz, M.2
Anagnostopoulos, I.3
Krappmann, D.4
Lietz, A.5
Jundt, F.6
Bommert, K.7
Mechta-Grigoriou, F.8
Stein, H.9
Dörken, B.10
Scheidereit, C.11
-
15
-
-
0043091963
-
Elevated c-Jun expression in acute myeloid leukemias inhibits C/EBPα DNA binding via leucine zipper domain interaction
-
Rangatia J, Vangala RK, Singh SM, Peer Zada AA, Elsässer A, Kohlmann A, Haferlach T, Tenen DG, Hiddemann W and Behre G: Elevated c-Jun expression in acute myeloid leukemias inhibits C/EBPα DNA binding via leucine zipper domain interaction. Oncogene 22: 4760-4764, 2003.
-
(2003)
Oncogene
, vol.22
, pp. 4760-4764
-
-
Rangatia, J.1
Vangala, R.K.2
Singh, S.M.3
Peer Zada, A.A.4
Elsässer, A.5
Kohlmann, A.6
Haferlach, T.7
Tenen, D.G.8
Hiddemann, W.9
Behre, G.10
-
16
-
-
33846674993
-
Genomic profiling of malignant pleural mesothelioma with array-based comparative genomic hybridization shows frequent non-random chromosomal alteration regions including JUN amplification on 1p32
-
Taniguchi T, Karnan S, Fukui T, Yokoyama T, Tagawa H, Yokoi K, Ueda Y, Mitsudomi T, Horio Y, Hida T, Yatabe Y, Seto M and Sekido Y: Genomic profiling of malignant pleural mesothelioma with array-based comparative genomic hybridization shows frequent non-random chromosomal alteration regions including JUN amplification on 1p32. Cancer Sci 98: 438-446, 2007.
-
(2007)
Cancer Sci
, vol.98
, pp. 438-446
-
-
Taniguchi, T.1
Karnan, S.2
Fukui, T.3
Yokoyama, T.4
Tagawa, H.5
Yokoi, K.6
Ueda, Y.7
Mitsudomi, T.8
Horio, Y.9
Hida, T.10
Yatabe, Y.11
Seto, M.12
Sekido, Y.13
-
17
-
-
0037462454
-
Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53
-
Eferl R, Ricci R, Kenner L, Zenz R, David JP, Rath M and Wagner EF: Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53. Cell 112: 181-192, 2003.
-
(2003)
Cell
, vol.112
, pp. 181-192
-
-
Eferl, R.1
Ricci, R.2
Kenner, L.3
Zenz, R.4
David, J.P.5
Rath, M.6
Wagner, E.F.7
-
18
-
-
22244453416
-
A robust algorithm for copy number detection using high-density oligonucleotide single nucleotide polymorphism genotyping arrays
-
Nannya Y, Sanada M, Nakazaki K, Hosoya N, Wang L, Hangaishi A, Kurokawa M, Chiba S, Bailey DK, Kennedy GC and Ogawa S: A robust algorithm for copy number detection using high-density oligonucleotide single nucleotide polymorphism genotyping arrays. Cancer Res 65: 6071-6079, 2005.
-
(2005)
Cancer Res
, vol.65
, pp. 6071-6079
-
-
Nannya, Y.1
Sanada, M.2
Nakazaki, K.3
Hosoya, N.4
Wang, L.5
Hangaishi, A.6
Kurokawa, M.7
Chiba, S.8
Bailey, D.K.9
Kennedy, G.C.10
Ogawa, S.11
-
19
-
-
13144267754
-
Positional cloning of ZNF217 and NABC1: Genes amplified at 20q13.2 and overexpressed in breast carcinoma
-
Collins C, Rommens JM, Kowbel D, Godfrey T, Tanner M, Hwang SI, Polikoff D, Nonet G, Cochran J, Myambo K, Jay KE, Froula J, Cloutier T, Kuo WL, Yaswen P, Dairkee S, Giovanola J, Hutchinson GB, Isola J, Kallioniemi OP, Palazzolo M, Martin C, Ericsson C, Pinkel D, Albertson D, Li WB and Gray JW: Positional cloning of ZNF217 and NABC1: genes amplified at 20q13.2 and overexpressed in breast carcinoma. Proc Natl Acad Sci USA 95: 8703-8708, 1998.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 8703-8708
-
-
Collins, C.1
Rommens, J.M.2
Kowbel, D.3
Godfrey, T.4
Tanner, M.5
Hwang, S.I.6
Polikoff, D.7
Nonet, G.8
Cochran, J.9
Myambo, K.10
Jay, K.E.11
Froula, J.12
Cloutier, T.13
Kuo, W.L.14
Yaswen, P.15
Dairkee, S.16
Giovanola, J.17
Hutchinson, G.B.18
Isola, J.19
Kallioniemi, O.P.20
Palazzolo, M.21
Martin, C.22
Ericsson, C.23
Pinkel, D.24
Albertson, D.25
Li, W.B.26
Gray, J.W.27
more..
-
20
-
-
0025223602
-
Integration of hepatitis B virus DNA into cells of six established human hepatocellular carcinoma cell lines
-
Fujise K, Nagamori S, Hasumura S, Homma S, Sujino H, Matsuura T, Shimizu K, Niiya M, Kameda H and Fujita K and Ohno T: Integration of hepatitis B virus DNA into cells of six established human hepatocellular carcinoma cell lines. Hepatogastroenterology 37: 457-460, 1990.
-
(1990)
Hepatogastroenterology
, vol.37
, pp. 457-460
-
-
Fujise, K.1
Nagamori, S.2
Hasumura, S.3
Homma, S.4
Sujino, H.5
Matsuura, T.6
Shimizu, K.7
Niiya, M.8
Kameda, H.9
Fujita, K.10
Ohno, T.11
-
21
-
-
0142213943
-
PTK2 and E1F3S3 genes may be amplification targets at 8q23-q24 and are associated with large hepatocellular carcinomas
-
Okamoto H, Yasui K, Zhao C, Arii S and Inazawa J: PTK2 and E1F3S3 genes may be amplification targets at 8q23-q24 and are associated with large hepatocellular carcinomas. Hepatology 38: 1242-1249, 2003.
-
(2003)
Hepatology
, vol.38
, pp. 1242-1249
-
-
Okamoto, H.1
Yasui, K.2
Zhao, C.3
Arii, S.4
Inazawa, J.5
-
22
-
-
35648950024
-
Genetically distinct and clinically relevant classification of hepatocellular carcinoma: Putative therapeutic targets
-
Katoh H, Ojima H, Kokubu A, Saito S, Kondo T, Kosuge T, Hosoda F, Imoto I, Inazawa J, Hirohashi S and Shibata T: Genetically distinct and clinically relevant classification of hepatocellular carcinoma: putative therapeutic targets. Gastroenterology 133: 1475-1486, 2007.
-
(2007)
Gastroenterology
, vol.133
, pp. 1475-1486
-
-
Katoh, H.1
Ojima, H.2
Kokubu, A.3
Saito, S.4
Kondo, T.5
Kosuge, T.6
Hosoda, F.7
Imoto, I.8
Inazawa, J.9
Hirohashi, S.10
Shibata, T.11
-
23
-
-
23744446307
-
Jun: Stealth, stability, and transformation
-
Vogt PK and Bader AG: Jun: stealth, stability, and transformation. Mol Cell 19: 432-433, 2005.
-
(2005)
Mol Cell
, vol.19
, pp. 432-433
-
-
Vogt, P.K.1
Bader, A.G.2
-
24
-
-
0027242180
-
c-Jun is essential for normal mouse development and hepatogenesis
-
Hilberg F, Aguzzi A, Howells N and Wagner EF: c-Jun is essential for normal mouse development and hepatogenesis. Nature 365: 179-181, 1993.
-
(1993)
Nature
, vol.365
, pp. 179-181
-
-
Hilberg, F.1
Aguzzi, A.2
Howells, N.3
Wagner, E.F.4
-
25
-
-
0033620648
-
Functions of c-Jun in liver and heart development
-
Eferl R, Sibilia M, Hilberg F, Fuchsbichler A, Kufferath I, Guertl B, Zenz R, Wagner EF and Zatloukal K: Functions of c-Jun in liver and heart development. J Cell Biol 145: 1049-1061, 1999.
-
(1999)
J Cell Biol
, vol.145
, pp. 1049-1061
-
-
Eferl, R.1
Sibilia, M.2
Hilberg, F.3
Fuchsbichler, A.4
Kufferath, I.5
Guertl, B.6
Zenz, R.7
Wagner, E.F.8
Zatloukal, K.9
-
26
-
-
0037007208
-
Impaired postnatal hepatocyte proliferation and liver regeneration in mice lacking c-Jun in the liver
-
Behrens A, Sibilia M, David JP, Möhle-Steinlein U, Tronche F, Schütz G and Wagner EF: Impaired postnatal hepatocyte proliferation and liver regeneration in mice lacking c-Jun in the liver. EMBO J 21: 1782-1790, 2002.
-
(2002)
EMBO J
, vol.21
, pp. 1782-1790
-
-
Behrens, A.1
Sibilia, M.2
David, J.P.3
Möhle-Steinlein, U.4
Tronche, F.5
Schütz, G.6
Wagner, E.F.7
|