메뉴 건너뛰기




Volumn 19, Issue 1, 2010, Pages 35-41

Biomarkers in cervical screening: Quantitative reverse transcriptase PCR analysis of P16 INK4a expression

Author keywords

Biomarker; Cervical cancer; Human papillomavirus; Liquid based cervical cytology; P16INK4a; Quantitative real time PCR

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A;

EID: 75149186107     PISSN: 09598278     EISSN: None     Source Type: Journal    
DOI: 10.1097/CEJ.0b013e32833233d4     Document Type: Article
Times cited : (13)

References (47)
  • 1
    • 1342312269 scopus 로고    scopus 로고
    • Virologic versus cytologic triage of women with equivocal pap smears: A meta-analysis of the accuracy to detect high-grade intraepithelial neoplasia
    • Arbyn M, Buntinx F, Van Ranst M, Paraskevaidis E, Martin-Hirsch P, Dillner J (2004). Virologic versus cytologic triage of women with equivocal Pap smears: a meta-analysis of the accuracy to detect high-grade intraepithelial neoplasia. J Natl Cancer Inst 96:280-293. (Pubitemid 38256273)
    • (2004) Journal of the National Cancer Institute , vol.96 , Issue.4 , pp. 280-293
    • Arbyn, M.1    Buntinx, F.2    Van Ranst, M.3    Paraskevaidis, E.4    Martin-Hirsch, P.5    Dillner, J.6
  • 2
    • 28844508294 scopus 로고    scopus 로고
    • Clinical utility of HPV-DNA detection: Triage of minor cervical lesions, follow-up of women treated for high-grade CIN: An update of pooled evidence
    • Arbyn M, Paraskevaidis E, Martin-Hirsch P, PrendivilleW, Dillner J (2005). Clinical utility of HPV-DNA detection: triage of minor cervical lesions, follow-up of women treated for high-grade CIN: an update of pooled evidence. Gynecol Oncol 99:7-11.
    • (2005) Gynecol Oncol , vol.99 , pp. 7-11
    • Arbyn, M.1    Paraskevaidis, E.2    Martin-Hirsch, P.3    Prendiville, W.4    Dillner, J.5
  • 3
    • 58349090025 scopus 로고    scopus 로고
    • Prevaccination distribution of human papillomavirus types in women attending at cervical cancer screening in Belgium
    • Arbyn M, Benoy I, Simoens C, Bogers J, Beutels P, Depuydt C (2009). Prevaccination distribution of human papillomavirus types in women attending at cervical cancer screening in Belgium. Cancer Epidemiol Biomarkers Prev 18:321-330.
    • (2009) Cancer Epidemiol Biomarkers Prev , vol.18 , pp. 321-330
    • Arbyn, M.1    Benoy, I.2    Simoens, C.3    Bogers, J.4    Beutels, P.5    Depuydt, C.6
  • 4
    • 0037363076 scopus 로고    scopus 로고
    • Translational approaches to improving cervical screening
    • Baldwin P, Laskey R, Coleman N (2003). Translational approaches to improving cervical screening. Nat Rev Cancer 3:217-226.
    • (2003) Nat Rev Cancer , vol.3 , pp. 217-226
    • Baldwin, P.1    Laskey, R.2    Coleman, N.3
  • 5
    • 0036320413 scopus 로고    scopus 로고
    • Real-time PCR technology for cancer diagnostics
    • Bernard PS, Wittwer CT (2002). Real-time PCR technology for cancer diagnostics. Clin Chem 48:1178-1185.
    • (2002) Clin Chem , vol.48 , pp. 1178-1185
    • Bernard, P.S.1    Wittwer, C.T.2
  • 8
    • 4644304965 scopus 로고    scopus 로고
    • P16(INK4A) expression is related to grade of CIN and high-risk human papillomavirus but does not predict virus clearance after conization or disease outcome
    • Branca M, Ciotti M, Santini D, Di Bonito L, Giorgi C, Benedetto A, et al. (2004). p16(INK4A) expression is related to grade of CIN and high-risk human papillomavirus but does not predict virus clearance after conization or disease outcome. Int J Gynecol Pathol 23:354-365.
    • (2004) Int J Gynecol Pathol , vol.23 , pp. 354-365
    • Branca, M.1    Ciotti, M.2    Santini, D.3    Di Bonito, L.4    Giorgi, C.5    Benedetto, A.6
  • 9
    • 54249106052 scopus 로고    scopus 로고
    • Human papillomavirus mRNA and p16 detection as biomarkers for the improved diagnosis of cervical neoplasia
    • Cuschieri K, Wentzensen N (2008). Human papillomavirus mRNA and p16 detection as biomarkers for the improved diagnosis of cervical neoplasia. Cancer Epidemiol Biomarkers Prev 17:2536-2545.
    • (2008) Cancer Epidemiol Biomarkers Prev , vol.17 , pp. 2536-2545
    • Cuschieri, K.1    Wentzensen, N.2
  • 10
    • 1842508232 scopus 로고    scopus 로고
    • Human papillomavirus type specific DNA and RNA persistence - Implications for cervical disease progression and monitoring
    • Cuschieri KS,Whitley MJ, Cubie HA (2004). Human papillomavirus type specific DNA and RNA persistence - implications for cervical disease progression and monitoring. J Med Virol 73:65-70.
    • (2004) J Med Virol , vol.73 , pp. 65-70
    • Cuschieri, K.S.1    Whitley, M.J.2    Cubie, H.A.3
  • 11
    • 12344264808 scopus 로고    scopus 로고
    • Assessment of human papillomavirus mRNA detection over time in cervical specimens collected in liquid-based cytology medium
    • Cuschieri KS, Beattie G, Hassan S, Robertson K, Cubie HA (2005). Assessment of human papillomavirus mRNA detection over time in cervical specimens collected in liquid-based cytology medium. J Virol Methods 124:211-215.
    • (2005) J Virol Methods , vol.124 , pp. 211-215
    • Cuschieri, K.S.1    Beattie, G.2    Hassan, S.3    Robertson, K.4    Cubie, H.A.5
  • 14
    • 0031803388 scopus 로고    scopus 로고
    • Characterization of RNA in cytologic samples preserved in a methanol-based collection solution
    • Dimulescu II, Unger ER, Lee DR, Reeves WC, Vernon SD (1998). Characterization of RNA in cytologic samples preserved in a methanol-based collection solution. Mol Diagn 3:67-71.
    • (1998) Mol Diagn , vol.3 , pp. 67-71
    • Dimulescu, I.I.1    Unger, E.R.2    Lee, D.R.3    Reeves, W.C.4    Vernon, S.D.5
  • 16
    • 2442643013 scopus 로고    scopus 로고
    • Molecular quality of exfoliated cervical cells: Implications for molecular epidemiology and biomarker discovery
    • Habis AH, Vernon SD, Lee DR, Verma M, Unger ER (2004). Molecular quality of exfoliated cervical cells: implications for molecular epidemiology and biomarker discovery. Cancer Epidemiol Biomarkers Prev 13:492-496.
    • (2004) Cancer Epidemiol Biomarkers Prev , vol.13 , pp. 492-496
    • Habis, A.H.1    Vernon, S.D.2    Lee, D.R.3    Verma, M.4    Unger, E.R.5
  • 17
    • 33846180716 scopus 로고    scopus 로고
    • A comparison of the clinical utility of p16(INK4a) immunolocalization with the presence of human papillomavirus by hybrid capture 2 for the detection of cervical dysplasia/ neoplasia
    • Holladay EB, Logan S, Arnold J, Knesel B, Smith GD (2006). A comparison of the clinical utility of p16(INK4a) immunolocalization with the presence of human papillomavirus by hybrid capture 2 for the detection of cervical dysplasia/ neoplasia. Cancer 108:451-461.
    • (2006) Cancer , vol.108 , pp. 451-461
    • Holladay, E.B.1    Logan, S.2    Arnold, J.3    Knesel, B.4    Smith, G.D.5
  • 19
    • 33748156619 scopus 로고    scopus 로고
    • Chapter 7: Achievements and limitations of cervical cytology screening
    • Kitchener HC, Castle PE, Cox TJ (2006). Chapter 7: achievements and limitations of cervical cytology screening. Vaccine 24S3:S3/63-S3/70.
    • (2006) Vaccine , vol.24 S3
    • Kitchener, H.C.1    Castle, P.E.2    Cox, T.J.3
  • 20
    • 0035871985 scopus 로고    scopus 로고
    • Overexpression of p16(INK4a) as a specific marker for dysplastic and neoplastic epithelial cells of the cervix uteri
    • Klaes R, Friedrich T, Spitkovsky D, Ridder R, Rudy W, Petry U, et al. (2001). Overexpression of p16(INK4a) as a specific marker for dysplastic and neoplastic epithelial cells of the cervix uteri. Int J Cancer 92:276-284.
    • (2001) Int J Cancer , vol.92 , pp. 276-284
    • Klaes, R.1    Friedrich, T.2    Spitkovsky, D.3    Ridder, R.4    Rudy, W.5    Petry, U.6
  • 21
    • 20444487245 scopus 로고    scopus 로고
    • DNA-versus RNA-based methods for human papillomavirus detection in cervical neoplasia
    • Lie AK, Risberg B, Borge B, Sandstad B, Delabie J, Rimala R, et al. (2005). DNA-versus RNA-based methods for human papillomavirus detection in cervical neoplasia. Gynecol Oncol 97:908-915.
    • (2005) Gynecol Oncol , vol.97 , pp. 908-915
    • Lie, A.K.1    Risberg, B.2    Borge, B.3    Sandstad, B.4    Delabie, J.5    Rimala, R.6
  • 22
  • 23
    • 65549146700 scopus 로고    scopus 로고
    • Gene expression profiling in cervical cancer: Identification of novel markers for disease diagnosis and therapy
    • Martin CM, Astbury K, McEvoy L, O'Toole S, Sheils O, O'Leary JJ (2009). Gene expression profiling in cervical cancer: identification of novel markers for disease diagnosis and therapy. Methods Mol Biol 511:333-359.
    • (2009) Methods Mol Biol , vol.511 , pp. 333-359
    • Martin, C.M.1    Astbury, K.2    McEvoy, L.3    O'Toole, S.4    Sheils, O.5    O'Leary, J.J.6
  • 24
    • 34247466557 scopus 로고    scopus 로고
    • Evaluation of p16INK4a expression in ThinPrep cervical specimens with the CINtec p16INK4a assay: Correlation with biopsy follow-up results
    • Meyer JL, Hanlon DW, Andersen BT, Rasmussen OF, Bisgaard K (2007). Evaluation of p16INK4a expression in ThinPrep cervical specimens with the CINtec p16INK4a assay: correlation with biopsy follow-up results. Cancer 1 1:83-92.
    • (2007) Cancer , vol.1 , Issue.1 , pp. 83-92
    • Meyer, J.L.1    Hanlon, D.W.2    Andersen, B.T.3    Rasmussen, O.F.4    Bisgaard, K.5
  • 25
    • 13944255794 scopus 로고    scopus 로고
    • Comparison of human papillomavirus messenger RNA and DNA detection: A cross-sectional study of 4136 women >30 years of age with a 2-year follow-up of high-grade squamous intraepithelial lesion
    • Molden T, Kraus I, Karlsen F, Skomedal H, Nygard JF, Hagmar B (2005). Comparison of human papillomavirus messenger RNA and DNA detection: a cross-sectional study of 4136 women >30 years of age with a 2-year follow-up of high-grade squamous intraepithelial lesion. Cancer Epidemiol Biomarkers Prev 14:367-372.
    • (2005) Cancer Epidemiol Biomarkers Prev , vol.14 , pp. 367-372
    • Molden, T.1    Kraus, I.2    Karlsen, F.3    Skomedal, H.4    Nygard, J.F.5    Hagmar, B.6
  • 26
    • 34247122719 scopus 로고    scopus 로고
    • PreTect HPV-Proofer: Real-time detection and typing of E6/E7 mRNA from carcinogenic human papillomaviruses
    • Molden T, Kraus I, Skomedal H, Nordstrøm T, Karlsen F (2007). PreTect HPV-Proofer: real-time detection and typing of E6/E7 mRNA from carcinogenic human papillomaviruses. J Virol Methods 142:204-212.
    • (2007) J Virol Methods , vol.142 , pp. 204-212
    • Molden, T.1    Kraus, I.2    Skomedal, H.3    Nordstrøm, T.4    Karlsen, F.5
  • 27
    • 0033914748 scopus 로고    scopus 로고
    • Risk factors for pre-cancerous lesions of the cervix
    • Murthy NS, Mathew A (2000). Risk factors for pre-cancerous lesions of the cervix. Eur J Cancer Prev 9:5-14.
    • (2000) Eur J Cancer Prev , vol.9 , pp. 5-14
    • Murthy, N.S.1    Mathew, A.2
  • 28
    • 0033818497 scopus 로고    scopus 로고
    • Ubiquitous presence of E6 and E7 transcripts in human papillomavirus-positive cervical carcinomas regardless of its type
    • Nakagawa S, Yoshikawa H, Yasugi T, Kimura M, Kawana K, Matsumoto K, et al. (2000). Ubiquitous presence of E6 and E7 transcripts in human papillomavirus-positive cervical carcinomas regardless of its type. J Med Virol 6 2:251-258.
    • (2000) J Med Virol , vol.6 , Issue.2 , pp. 251-258
    • Nakagawa, S.1    Yoshikawa, H.2    Yasugi, T.3    Kimura, M.4    Kawana, K.5    Matsumoto, K.6
  • 29
    • 35349004609 scopus 로고    scopus 로고
    • Human papillomavirus and Papanicolaou tests to screen for cervical cancer
    • Naucler P, Ryd W, Tö rnberg S, Strand A, Wadell G, Elfgren K, et al. (2007). Human papillomavirus and Papanicolaou tests to screen for cervical cancer. N Engl J Med 18:1589-1597.
    • (2007) N Engl J Med , vol.18 , pp. 1589-1597
    • Naucler, P.1    Ryd, W.2    Tö Rnberg, S.3    Strand, A.4    Wadell, G.5    Elfgren, K.6
  • 31
    • 33748761925 scopus 로고    scopus 로고
    • Chapter 2: The burden of HPV-related cancers
    • Parkin DM, Bray F (2006). Chapter 2: the burden of HPV-related cancers. Vaccine 24:S11-S25.
    • (2006) Vaccine , vol.24
    • Parkin, D.M.1    Bray, F.2
  • 32
    • 0034523727 scopus 로고    scopus 로고
    • Liquid-based cytology for cervical screening
    • Payne N, Chilcott J, McGoogan E (2000). Liquid-based cytology for cervical screening. Cytopathology 11:469-470.
    • (2000) Cytopathology , vol.11 , pp. 469-470
    • Payne, N.1    Chilcott, J.2    McGoogan, E.3
  • 33
    • 33746907110 scopus 로고    scopus 로고
    • Recovery of human papillomavirus nucleic acids from liquid-based cytology media
    • Powell N, Smith K, Fiander A (2006). Recovery of human papillomavirus nucleic acids from liquid-based cytology media. J Virol Methods 137:58-62.
    • (2006) J Virol Methods , vol.137 , pp. 58-62
    • Powell, N.1    Smith, K.2    Fiander, A.3
  • 36
    • 31844433618 scopus 로고    scopus 로고
    • Immunocytochemistry in liquid-based cervical cytology: Analysis of clinical use following a cross-sectional study
    • Sahebali S, Depuydt CE, Boulet GA, Arbyn M, Moeneclaey LM, Vereecken AJ, et al. (2006). Immunocytochemistry in liquid-based cervical cytology: analysis of clinical use following a cross-sectional study. Int J Cancer 118:1254-1260.
    • (2006) Int J Cancer , vol.118 , pp. 1254-1260
    • Sahebali, S.1    Depuydt, C.E.2    Boulet, G.A.3    Arbyn, M.4    Moeneclaey, L.M.5    Vereecken, A.J.6
  • 37
    • 0036895918 scopus 로고    scopus 로고
    • Overexpression of p16INK4A in liquid-based specimens (SurePath) as a maker of cervical dysplasia and neoplasia
    • Saqi A, Pasha TL, McGrath CM, Yu GH, Zhang P, Gupta P (2002). Overexpression of p16INK4A in liquid-based specimens (SurePath) as a maker of cervical dysplasia and neoplasia. Diagn Cytopathol 27:365-370.
    • (2002) Diagn Cytopathol , vol.27 , pp. 365-370
    • Saqi, A.1    Pasha, T.L.2    McGrath, C.M.3    Yu, G.H.4    Zhang, P.5    Gupta, P.6
  • 38
    • 0037165740 scopus 로고    scopus 로고
    • The 2001 Bethesda System: Terminology for reporting results of cervical cytology
    • Solomon D, Davey D, Kurman R, Moriarty A, O'Connor D, Prey M, et al. (2002). The 2001 Bethesda System: terminology for reporting results of cervical cytology. JAMA 287:2114-2119.
    • (2002) JAMA , vol.287 , pp. 2114-2119
    • Solomon, D.1    Davey, D.2    Kurman, R.3    Moriarty, A.4    O'Connor, D.5    Prey, M.6
  • 39
    • 32944464489 scopus 로고    scopus 로고
    • DNA and RNA references for qRTPCR in exfoliated cervical cells
    • Steinau M, Rajeevan MS, Unger ER (2006). DNA and RNA references for qRTPCR in exfoliated cervical cells. J Mol Diagn 8:113-118.
    • (2006) J Mol Diagn , vol.8 , pp. 113-118
    • Steinau, M.1    Rajeevan, M.S.2    Unger, E.R.3
  • 40
    • 0034943647 scopus 로고    scopus 로고
    • Improved detection of viral RNA isolated from liquid-based cytology samples
    • The Atypical Squamous Cells of Undetermined Significance/Low-Grade
    • Tarkowski TA, Rajeevan MS, Lee DR, Unger ER (2001). Improved detection of viral RNA isolated from liquid-based cytology samples. Mol Diagn 6:125-130. The Atypical Squamous Cells of Undetermined Significance/Low-Grade
    • (2001) Mol Diagn , vol.6 , pp. 125-130
    • Tarkowski, T.A.1    Rajeevan, M.S.2    Lee, D.R.3    Unger, E.R.4
  • 41
    • 0034162683 scopus 로고    scopus 로고
    • Human papillomavirus testing for triage of women with cytologic evidence of low-grade squamous intraepithelial lesions: Baseline data from a randomized trial
    • Squamous Intraepithelial Lesions Triage Study (ALTS) Group
    • Squamous Intraepithelial Lesions Triage Study (ALTS) Group (2000). Human papillomavirus testing for triage of women with cytologic evidence of low-grade squamous intraepithelial lesions: baseline data from a randomized trial. J Natl Cancer Inst 92:397-402.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 397-402
  • 42
    • 64249149339 scopus 로고    scopus 로고
    • P16(INK4a) immunostaining in cytological and histological specimens from the uterine cervix: A systematic review and meta-analysis
    • Tsoumpou I, Arbyn M, Kyrgiou M,Wentzensen N, Koliopoulos G, Martin-Hirsch P, et al. (2009). p16(INK4a) immunostaining in cytological and histological specimens from the uterine cervix: a systematic review and meta-analysis. Cancer Treat Rev 35:210-220.
    • (2009) Cancer Treat Rev , vol.35 , pp. 210-220
    • Tsoumpou, I.1    Arbyn, M.2    Kyrgiou, M.3    Wentzensen, N.4    Koliopoulos, G.5    Martin-Hirsch, P.6
  • 43
    • 30344474927 scopus 로고    scopus 로고
    • Evaluation of a nuclear score for p16INK4a-stained cervical squamous cells in liquid-based cytology samples
    • Wentzensen N, Bergeron C, Cas F, Eschenbach D, Vinokurova S, von Knebel Doeberitz M (2005). Evaluation of a nuclear score for p16INK4a-stained cervical squamous cells in liquid-based cytology samples. Cancer 105:461-467.
    • (2005) Cancer , vol.105 , pp. 461-467
    • Wentzensen, N.1    Bergeron, C.2    Cas, F.3    Eschenbach, D.4    Vinokurova, S.5    Von Knebel Doeberitz, M.6
  • 44
    • 0033766255 scopus 로고    scopus 로고
    • Influence of DNA target melting behavior on real-time PCR quantification
    • Wilhelm J, Hahn M, Pingoud A (2000). Influence of DNA target melting behavior on real-time PCR quantification. Clin Chem 46:1738-1743.
    • (2000) Clin Chem , vol.46 , pp. 1738-1743
    • Wilhelm, J.1    Hahn, M.2    Pingoud, A.3
  • 45
    • 34249909244 scopus 로고    scopus 로고
    • Cervical cancer screening in the 21st century: Is it time to retire the PAP smear?
    • Wright TC (2007). Cervical cancer screening in the 21st century: is it time to retire the PAP smear? Clin Obstet Gynecol 50:313-323.
    • (2007) Clin Obstet Gynecol , vol.50 , pp. 313-323
    • Wright, T.C.1
  • 46
    • 34249847815 scopus 로고    scopus 로고
    • Efficiency of immunohistochemical p16 expression and HPV typing in cervical squamous intraepithelial lesion grading and review of the p16 literature
    • Yildiz IZ, Usubütün A, Firat P, Ayhan A, Kücükali T (2007). Efficiency of immunohistochemical p16 expression and HPV typing in cervical squamous intraepithelial lesion grading and review of the p16 literature. Pathol Res Pract 203:445-449.
    • (2007) Pathol Res Pract , vol.203 , pp. 445-449
    • Yildiz, I.Z.1    Usubütün, A.2    Firat, P.3    Ayhan, A.4    Kücükali, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.