Role of Low-Affinity Nerve Growth Factor Receptor Inhibitory Antibody in Reducing Pain Behavior and Calcitonin Gene-Related Peptide Expression in a Rat Model of Wrist Joint Inflammatory Pain

Journal of Hand Surgery

Volumn 35, Issue 2, 2010, Pages 267-273

  Iwakura, Nahoko ^a   Ohtori, Seiji ^a   Orita, Sumihisa ^a   Yamashita, Masaomi ^a   Takahashi, Kazuhisa ^a   Kuniyoshi, Kazuki ^a  

^a CHIBA UNIVERSITY   (Japan)

Author keywords

calcitonin gene related peptide; joint; p75 neurotrophin receptor; pain; Wrist

Indexed keywords

ANALGESIC AGENT; CALCITONIN GENE RELATED PEPTIDE; FREUND ADJUVANT; NERVE GROWTH FACTOR RECEPTOR; NEUROTROPHIN RECEPTOR P75 ANTIBODY; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANOREXIA; ARTHRALGIA; ARTICLE; BRAIN NERVE CELL; CERVICAL SPINE; COMPARATIVE STUDY; CONSTIPATION; CONTROL GROUP; CONTROLLED STUDY; HYPERALGESIA; IMMUNOCHEMISTRY; IMMUNOREACTIVITY; INFECTION; INJECTION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL GANGLION; UPREGULATION; WEIGHT REDUCTION; WRIST;

ANIMALS; ARTHRALGIA; BEHAVIOR, ANIMAL; CALCITONIN GENE-RELATED PEPTIDE; DISEASE MODELS, ANIMAL; FREUND'S ADJUVANT; INJECTIONS, INTRA-ARTICULAR; MALE; PAIN MEASUREMENT; PAIN THRESHOLD; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, NERVE GROWTH FACTOR; REFERENCE VALUES; SENSITIVITY AND SPECIFICITY; WRIST JOINT;

EID: 75149182097     PISSN: 03635023     EISSN: 15316564     Source Type: Journal    
DOI: 10.1016/j.jhsa.2009.10.030     Document Type: Article

References (28)

1. Fukumoto K., Kojima T., Kinoshita Y., and Koda M. An anatomic study of the innervation of the wrist joint and Wilhelm's technique for denervation. J Hand Surg 18A (1993) 484-489
2. Cavalcante M.L., Rodrigues C.J., and Mattar Jr. R. Mechanoreceptors and nerve endings of the triangular fibrocartilage in the human wrist. J Hand Surg 29A (2004) 432-438
3. Gupta R., Nelson S.D., Baker J., Jones N.F., and Meals R.A. The innervation of the triangular fibrocartilage complex: nitric acid maceration rediscovered. Plast Reconstr Surg 107 (2001) 135-139
4. Hagert E., Ljung B.O., and Forsgren S. General innervation pattern and sensory corpuscles in the scapholunate interosseous ligament. Cells Tissues Organs 177 (2004) 47-54
5. Ohmori M., and Azuma H. Morphology and distribution of nerve endings in the human triangular fibrocartilage complex. J Hand Surg 23B (1998) 522-525
6. Kuniyoshi K., Ohtori S., Ochiai N., Murata R., Matsudo T., Yamada T., et al. Characteristics of sensory DRG neurons innervating the wrist joint in rats. Eur J Pain 11 (2007) 323-328
7. Aloe L., Tuveri M.A., Carcassi U., and Levi-Montalcini R. Nerve growth factor in the synovial fluid of patients with chronic arthritis. Arthritis Rheum 35 (1992) 351-355
8. Halliday D.A., Zettler C., Rush R.A., Scicchitano R., and McNeil J.D. Elevated growth factor levels in the synovial fluid of patients with inflammatory joint disease. Neurochem Res 23 (1998) 919-922
9. Andreev N.Yu., Dimitrieva N., Kolzenburg M., and McMahon S.B. Peripheral administration of nerve growth factor in the adult rat produces a thermal hyperalgesia that requires the presence of sympathetic post-ganglionic neurones. Pain 63 (1995) 109-115
10. Apfel S.C. Nerve growth factor for the treatment of diabetic neuropathy: what went wrong, what went right, and what does the future hold?. Int Rev Neurobiol 50 (2002) 393-413
11. Sah D.W., Ossipov M.H., and Porecca F. Neurotrophic factors as novel therapeutics for neuropathic pain. Nat Rev Drug Discov 2 (2003) 460-472
12. Sugiura A., Ohtori S., Yamashita M., Inoue G., Yamauchi K., Koshi T., et al. Existence of nerve growth factor receptors, tyrosine kinase a and p75 neurotrophin receptors in intervertebral discs and on dorsal root ganglion neurons innervating intervertebral discs in rats. Spine 33 (2008) 2047-2051
13. Woolf C.J., Safieh-Garabedian B., Ma Q.P., Crilly P., and Winter J. Nerve growth factor contributes to the generation of inflammatory sensory hypersensitivity. Neuroscience 62 (1994) 327-331
14. Obata K., Katsura H., Sakurai J., Kobayashi K., Yamanaka H., Dai Y., et al. Suppression of the p75 neurotrophin receptor in uninjured sensory neurons reduces neuropathic pain after nerve injury. J Neurosci 26 (2006) 11974-11986
15. Watanabe T., Ito T., Inoue G., Ohtori S., Kitajo K., Doya H., et al. The p75 receptor is associated with inflammatory thermal hypersensitivity. J Neurosci Res 86 (2008) 3566-3574
16. Miller F.D., and Kaplan D.R. On Trk for retrograde signaling. Neuron 32 (2001) 767-770
17. Nykjaer A., Willnow T.E., and Petersen C.M. p75NTR: live or let die. Curr Opin Neurobiol 15 (2005) 49-57
18. Takasaki I., Andoh T., Shiraki K., and Kuraishi Y. Hyperalgesia and hyperalgesia induced by herpes simplex virus type-1 infection in mice. Pain 86 (2000) 95-101
19. Nakayama K., Masuko S., Tsuruta T., Kutsuna T., and Watanabe H. Vascularization and innervation of the canine wrist joint synovial membrane. Tohoku J Exp Med 175 (1995) 195-209
20. Nishigami T., Osako Y., Tanaka K., Yuri K., Kawasaki M., Ikemoto T., et al. Changes in calcitonin gene-related peptide expression following joint immobilization in rats. Neurosci Lett 454 (2009) 97-100
21. Shigemitsu T., Tobe M., Mizutani K., Murakami K., Ishikawa Y., and Sato F. Innervation of the triangular fibrocartilage complex of the human wrist: quantitative immunohistochemical study. Anat Sci Int 82 (2007) 127-132
22. Lindsay R.M., and Harmar A.J. NGF regulates expression of neuropeptide genes in adult sensory neurons. Nature 337 (1989) 362-364
23. Verge V.M., Merlio J.P., Grondin J., Ernfors P., Persson H., Riopelle R.J., et al. Colocalization of NGF binding sites, trk mRNA, and low-affinity NGF receptor mRNA in primary sensory neurons: responses to injury and infusion of NGF. J Neurosci 12 (1992) 4011-4022
24. Mousa S.A., Cheppudira B.P., Shaqura M., Fischer O., Hofmann J., Hellweg R., et al. Nerve growth factor governs the enhanced ability of opioids to suppress inflammatory pain. Brain 130 (2007) 502-513
25. Delcroix J.D., Patel J., Averill S., Tomlinson D.R., Priestley J.V., and Fernyhough P. Peripheral axon crush elevates transport of p75NTR in the central projection of sensory neurones of rats. Neurosci Lett 351 (2003) 181-185
26. Barker P.A. High affinity not in the vicinity?. Neuron 53 (2007) 1-4
27. Wehrman T., He X., Raab B., Dukipatti A., Blau H., and Garcia K.C. Structural and mechanistic insights into nerve growth factor interactions with the TrkA and p75 receptors. Neuron 53 (2007) 25-38
28. Lane N., Webster L., Lu S.-p., Gray M., Hefti F., and Walicke P. RN624 (anti-NGF) improves pain and function in subjects with moderate knee osteoarthritis: a phase I study. Arthritis Rheum 52 (2005) S461