Growth factors enhance endothelial progenitor cell proliferation under high-glucose conditions

Medical Science Monitor

Volumn 15, Issue 12, 2009, Pages

  Li, Wei ^a,b,c   Yang, Shiyu Y ^a   Hu, Zhong F ^b   Winslet, Marc C ^a,c   Wang, Wen ^b   Seifalian, Alexander M ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^c ROYAL FREE LONDON NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Cell based therapeutic intervention; Endothelial progenitor cells; Growth factor; High glucose ambient; Proliferation

Indexed keywords

GLUCOSE; GROWTH FACTOR; SOMATOMEDIN C;

ARTICLE; BLOOD SAMPLING; CELL PROLIFERATION; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; MECHANORECEPTOR; NORMAL HUMAN; STEM CELL;

ADULT STEM CELLS; CELL PROLIFERATION; ENDOTHELIAL CELLS; GLUCOSE; GROWTH SUBSTANCES; HUMAN GROWTH HORMONE; HUMANS; IMMUNOHISTOCHEMISTRY; INSULIN-LIKE GROWTH FACTOR I;

EID: 75149179710     PISSN: 12341010     EISSN: 16433750     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Besler C, Doerries C, Giannotti G et al: Pharmacological approaches to improve endothelial repair mechanisms. Expert Rev Cardiovasc Ther, 2008; 6: 1071-82
2. Liew A, Barry F, O'Brien T: Endothelial progenitor cells: diagnostic and therapeutic considerations. Bioessays, 2006; 28: 261-70
3. Park DH, Borlongan CV, Eve DJ, Sanberg PR: The emerging field of cell and tissue engineering. Med Sci Monit, 2008; 14(11): RA206-20
4. Yu G, Borlongan CV, Stahl CE et al: Transplantation of human umbilical cord blood cells for the repair of myocardial infarction. Med Sci Monit, 2008; 14(10): RA163-72
5. Tarnowski M, Sieron AL: Adult stem cells and their ability to differentiate. Med Sci Monit 2006; 12(8): RA154-63
6. Punshon G, Sales KM, Vara DS et al: Assessment of the potential of progenitor stem cells extracted from human peripheral blood for seeding a novel vascular graft material. Cell Prolif, 2008; 41: 321-35
7. Asahara T, Murohara T, Sullivan A et al: Isolation of putative progenitor endothelial cells for angiogenesis. Science, 1997; 275: 964-67
8. Marsboom G, Janssens S: Endothelial progenitor cells: new perspectives and applications in cardiovascular therapies. Expert Rev Cardiovasc Ther, 2008; 6: 687-701
9. Fadini GP, Sartore S, Albiero M et al: Number and function of endothelial progenitor cells as a marker of severity for diabetic vasculopathy. Arterioscler Thromb Vasc Biol, 2006; 26: 2140-46
10. Loomans CJ, De Koning EJ, Staal FJ et al: Endothelial progenitor cell dysfunction: a novel concept in the pathogenesis of vascular complications of type 1 diabetes. Diabetes, 2004; 53: 195-99
11. Aziz MTA, El-Asmar MF, Haidara M et al: Effect of bone marrow-derived mesenchymal stem cells on cardiovascular complications in diabetic rats. Med Sci Monit, 2008; 14(11): BR249-55
12. Thum T, Hoeber S, Froese S et al: Age-dependent impairment of endothelial progenitor cells is corrected by growth hormone mediated increase of insulin-like growth factor-1. Circulation Research, 2007; 100: 434-43
13. Devin JK, Young PP: The effects of growth hormone and insulin-like growth factor-1 on the aging cardiovascular system and its progenitor cells. Curr Opin Investig Drugs, 2008; 9: 983-92
14. Ates K, Yang SY, Orrell RW et al: The IGF-I splice variant MGF increases progenitor cells in ALS, dystrophic, and normal muscle. Febs Letters, 2007; 581: 2727-32
15. Hayden MR, Tyagi SC: Neural redox stress and remodeling in metabolic syndrome, type 2 diabetes mellitus, and diabetic neuropathy. Med Sci Monit, 2004; 10(12): RA291-307
16. Alobaid N, Salacinski HJ, Sales KM et al: Nanocomposite containing bioactive peptides promote endothelialisation by circulating progenitor cells: An in vitro evaluation. Eur J Vasc Endovasc Surg, 2006; 32: 76-83
17. Foubert P, Matrone G, Souttou B et al: Coadministration of endothelial and smooth muscle progenitor cells enhances the efficiency of proangiogenic cell-based therapy. Circ Res, 2008; 103: 751-60
18. Akturk M, Arslan M, Altinova A et al: Association of serum levels of IGFI and IGFBP-1 with renal function in patients with type 2 diabetes mellitus. Growth Horm IGF Res, 2007; 17: 186-93
19. Goldspink G: Impairment of IGF-I gene splicing and MGF expression associated with muscle wasting. Int J Biochem Cell Biol, 2005; 37: 2012-22
20. Rivard A, Silver M, Chen DF et al: Rescue of diabetes-related impairment of angiogenesis by intramuscular gene therapy with adeno-VEGF. Am J Pathol, 1999; 154: 355-63
21. Chen YH, Lin SJ, Lin FY et al: High glucose impairs early and late endothelial progenitor cells by modifying nitric oxide-related but not oxidative stress-mediated mechanisms. Diabetes, 2007; 56: 1559-68
22. Weimann BJ, Lorch E, Baumgartner HR: High Glucose-Concentrations do Not Influence Replication and Prostacyclin Release of Human-Endothelial Cells. Diabetologia, 1984; 27: 62-63
23. Tepper OM, Galiano RD, Capla JM et al: Human endothelial progenitor exhibit impaired proliferation, cells from type II diabetics adhesion, and incorporation into vascular structures. Circulation, 2002; 106: 2781-86
24. Zhang W, Wang XH, Chen SF et al: Biphasic response of endothelial progenitor cell proliferation induced by high glucose and its relationship with reactive oxygen species. J Endocrinol, 2008; 197: 463-70
25. Kalka C, Masuda H, Takahashi T et al: Transplantation of ex vivo expanded endothelial progenitor cells for therapeutic neovascularization. Proc Natl Acad Sci USA, 2000; 97: 3422-27