Acute signalling responses to intense endurance training commenced with low or normal muscle glycogen: Experimental Physiology-Research Paper

Experimental Physiology

Volumn 95, Issue 2, 2010, Pages 351-358

  Yeo, Wee Kian ^a   McGee, Sean L ^b   Carey, Andrew L ^a   Paton, Carl D ^c   Garnham, Andrew P ^d   Hargreaves, Mark ^b   Hawley, John A ^a  

^a RMIT UNIVERSITY   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c EASTERN INSTITUTE OF TECHNOLOGY   (New Zealand)

^d DEAKIN UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE PHOSPHATE; GLYCOGEN; MITOGEN ACTIVATED PROTEIN KINASE P38; OXIDOREDUCTASE; PROTEIN KINASE;

ADULT; AEROBIC EXERCISE; ARTICLE; ATHLETE; CLINICAL ARTICLE; CONTROLLED STUDY; CYCLING; ENDURANCE; ENZYME LOCALIZATION; ENZYME SUBSTRATE; FITNESS; GLYCOGEN MUSCLE LEVEL; HUMAN; HUMAN EXPERIMENT; MALE; MUSCLE BIOPSY; PHOSPHORYLATION; SIGNAL TRANSDUCTION; SKELETAL MUSCLE;

EID: 75149179137     PISSN: 09580670     EISSN: 1469445X     Source Type: Journal    
DOI: 10.1113/expphysiol.2009.049353     Document Type: Article

References (27)

1. Akimoto T, Pohnert SC, Li P, Zhang M, Gumbs C, Rosenberg PB, Williams RS Yan Z (2005). Exercise stimulates Pgc-1α transcription in skeletal muscle through activation of the p38 MAPK pathway. J Biol Chem 280, 19587 19593.
2. Baar K McGee SL (2008). Optimizing training adaptations by manipulating glycogen. Eur J Sport Sci 8, 97 106.
3. Branvold DJ, Allred DR, Beckstead DJ, Kim HJ, Fillmore N, Condon BM, Brown JD, Sudweeks SN, Thomson DM Winder WW (2008). Thyroid hormone effects on LKB1, MO25, phospho-AMPK, phospho-CREB, and PGC-1α in rat muscle. J Appl Physiol 105, 1218 1227.
4. + metabolism and SIRT1 activity. Nature 458, 1056 1060.
5. Chan MHS, McGee SL, Watt MJ, Hargreaves M Febbraio MA (2004). Altering dietary nutrient intake that reduces glycogen content leads to phosphorylation of nuclear p38 MAP kinase in human skeletal muscle: association with IL-6 gene transcription during contraction. FASEB J 18, 1785 1787.
6. Churchley EG, Coffey VG, Pedersen DJ, Shield A, Carey KA, Cameron-Smith D Hawley JA (2007). Influence of preexercise muscle glycogen content on transcriptional activity of metabolic and myogenic genes in well-trained humans. J Appl Physiol 102, 1604 1611.
7. Coyle EF (2000). Physical activity as a metabolic stressor. Am J Clin Nutr 72, 512S 520S.
8. Fan M, Rhee J, St-Pierre J, Handschin C, Puigserver P, Lin J, Jäeger S, Erdjument-Bromage H, Tempst P Spiegelman BM (2004). Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1α: modulation by p38 MAPK. Genes Dev 18, 278 289.
9. Garcia-Roves P, Huss JM, Han DH, Hancock CR, Iglesias-Gutierrez E, Chen M Holloszy JO (2007). Raising plasma fatty acid concentration induces increased biogenesis of mitochondria in skeletal muscle. Proc Natl Acad Sci USA 104, 10709 10713.
10. Hansen AK, Fischer CP, Plomgaard P, Andersen JL, Saltin B Pedersen BK (2005). Skeletal muscle adaptation: training twice every second day vs. training once daily. J Appl Physiol 98, 93 99.
11. Hawley JA Noakes TD (1992). Peak power output predicts maximal oxygen uptake and performance time in trained cyclists. Eur J Appl Physiol Occup Physiol 65, 79 83.
12. Hawley JA, Tipton KD Millard-Stafford ML (2006). Promoting training adaptations through nutritional interventions. J Sports Sci 24, 709 721.
13. Irrcher I, Ljubicic V, Kirwan AF Hood DA (2008). AMP-activated protein kinase-regulated activation of the PGC-1α promoter in skeletal muscle cells. PLoS ONE 3, e3614.
14. Jäger S, Handschin C, St-Pierre J Spiegelman BM (2007). AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α. Proc Natl Acad Sci USA 104, 12017 12022.
15. Ljubicic V Hood DA (2009). Specific attenuation of protein kinase phosphorylation in muscle with a high mitochondrial content. Am J Physiol Endocrinol Metab 297, E749 E758.
16. McBride A, Ghilagaber S, Nikolaev A Hardie DG (2009). The glycogen-binding domain on the AMPK β subunit allows the kinase to act as a glycogen sensor. Cell Metab 9, 23 34.
17. McGee SL Hargreaves M (2004). Exercise and myocyte enhancer factor 2 regulation in human skeletal muscle. Diabetes 53, 1208 1214. (Pubitemid 38569005)
18. McGee SL, van Denderen BJW, Howlett KF, Mollica J, Schertzer JD, Kemp BE Hargreaves M (2008). AMP-activated protein kinase regulates GLUT4 transcription by phosphorylating histone deacetylase 5. Diabetes 57, 860 867.
19. Pilegaard H, Ordway GA, Saltin B Neufer PD (2000). Transcriptional regulation of gene expression in human skeletal muscle during recovery from exercise. Am J Physiol Endocrinol Metab 279, E806 E814.
20. Reznick RM Shulman GI (2006). The role of AMP-activated protein kinase in mitochondrial biogenesis. J Physiol 574, 33 39.
21. Steinberg GR, Watt MJ, McGee SL, Chan S, Hargreaves M, Febbraio MA, Stapleton D Kemp BE (2006). Reduced glycogen availability is associated with increased AMPKα2 activity, nuclear AMPKα2 protein abundance, and GLUT4 mRNA expression in contracting human skeletal muscle. Appl Physiol Nutr Metab 31, 302 312.
22. Thomson DM, Herway ST, Fillmore N, Kim H, Brown JD, Barrow JR Winder WW (2008). AMP-activated protein kinase phosphorylates transcription factors of the CREB family. J Appl Physiol 104, 429 438.
23. Widegren U, Ryder JW Zierath JR (2001). Mitogen-activated protein kinase signal transduction in skeletal muscle: effects of exercise and muscle contraction. Acta Physiol Scand 172, 227 238.
24. Wojtaszewski JFP, MacDonald C, Nielsen JN, Hellsten Y, Hardie DG, Kemp BE, Kiens B Richter EA (2003). Regulation of 5′AMP-activated protein kinase activity and substrate utilization in exercising human skeletal muscle. Am J Physiol Endocrinol Metab 284, E813 E822.
25. Yeo WK, Lessard SJ, Chen Z-P, Garnham AP, Burke LM, Rivas DA, Kemp BE Hawley JA (2008a). Fat adaptation followed by carbohydrate restoration increases AMPK activity in skeletal muscle from trained humans. J Appl Physiol 105, 1519 1526.
26. Yeo WK, Paton CD, Garnham AP, Burke LM, Carey AL Hawley JA (2008b). Skeletal muscle adaptation and performance responses to once a day versus twice every second day endurance training regimens. J Appl Physiol 105, 1462 1470.
27. Yu M, Stepto NK, Chibalin AV, Fryer LGD, Carling D, Krook A, Hawley JA Zierath JR (2003). Metabolic and mitogenic signal transduction in human skeletal muscle after intense cycling exercise. J Physiol 546, 327 335.