Overview of positron emission tomography chemistry: Clinical and technical considerations and combination with computed tomography

Journal of B.U.ON.

Volumn 14, Issue 4, 2009, Pages 575-580

  Koukourakis, G ^a   Maravelis, G ^a   Koukouraki, S ^b   Padelakos, P ^a   Kouloulias, V ^a  

^a UNIVERSITY OF ATHENS   (Greece)

^b UNIVERSITY HOSPITAL OF HERAKLION   (Greece)

Author keywords

Clinical applications; Pharmaceuticals; Positron emission tomography

Indexed keywords

6 FLUORODOPA F 18; CONTRAST MEDIUM; FLUORODEOXYGLUCOSE F 18; IODINATED CONTRAST MEDIUM; SODIUM FLUORIDE F 18; TRACER; UNCLASSIFIED DRUG;

AMPLITUDE MODULATION; ARTIFACT REDUCTION; CANCER SCINTISCANNING; CHEMICAL MODIFICATION; COMPUTER ASSISTED EMISSION TOMOGRAPHY; COMPUTER ASSISTED TOMOGRAPHY; DRUG DESIGN; DRUG METABOLISM; DRUG MONITORING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; IMAGE ANALYSIS; IMAGE ENHANCEMENT; IMAGE PROCESSING; IMAGE QUALITY; ISOTOPE LABELING; REVIEW; THORACIC CAVITY;

ANIMALS; HUMANS; NEOPLASMS; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 75149173092     PISSN: 11070625     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (21)

1. Hamacher K, Coenen HH, Stocklin G. Efficient stereospecific synthesis of NCA 2-[18F]-fluoro-2-deoxy-D-glucose using aminopolyether supported nucleophilic substitution. J Nucl Med 1986; 27: 235-238.
2. Kabalka GW, Lambrecht RM, Fowler JS et al. Synthesis of 150-labelled butanol via organoborane chemistry. Appl Radiat Isot 1985; 36: 853-855.
3. Luxen A, Guillaume M, Melega WP et al. Production of 6-[18F] fluoro-L-dopa and its metabolism in vivo -a critical review. Nucl Med Biol 1992; 19: 149-158.
4. Machulla HJ, Blocher A, Kuntzch M et al. Simplified labeling approach for synthesizing 3'A-deoxy-3'A-[18F]fluoro-thymidine [18F]FLT. J Radioanal Nucl Chem 2000; 243: 843-851.
5. Maziore B, Coenen HH, Haldin C et al. PET radioligands for dopamine receptors and re-uptake sites: chemistry and biochemistry. Nucl Med Biol 1992; 19: 497-512.
6. Meyer GJ, Ostercholz A, Handeshagen H. 150-water constant infusion system for clinical routine application. J Label Comp Radiopharm 1986; 23: 1209-1219.
7. Saha GB (Ed). Fundamentals of Nuclear Pharmacy (5th Edn). New York: Springer-Verlag, 2004.
8. Stocklin G, Pike VW (Eds). Radiopharmaceuticals for Positron Emission Tomography. Dordrecht, The Netherlands: Kluwer Academic, 1993.
9. U.S. Pharmacopeia 26 & National Formulary 21. United States Pharmaceutical Convention, Rockville, MD, 2003.
10. Welch MJ, Kilbourn MR. A remote system for the routine production of oxygen- 15 radiopharmaceuticals. J Label Comp Radiopharm 1985; 22: 1193-1201.
11. Wieland D, Bida G, Padgett H et al. In-target production of [13N] ammonia via proton irradiation of dilute aqueous ethanol and acetic acid mixtures. Appl Radiat Isot 1991; 42: 1095-1112.
12. Antoch G, Freudenberg LS, Egelhof T et al. Focal tracer up-take: a potential artifact in contrast-enhanced dual-modality PET/CT scans. J Nucl Med 2002; 43: 1339-1342.
13. Mawlawi O, Erasmus JJ, Munden RF et al. Quantifying the effect of IV contrast media on integrated PET/CT: clinical evaluation. AJR 2006; 186: 308-319.
14. Beyer T, Antoch G, Bockisch A, Stattaus J. Optimized intravenous contrast administration for diagnostic whole-body 18F-FDG PET/CT. J Nucl Med 2005; 46: 429-435.
15. Lonn AH. Evaluation of method to minimize the effect of X-ray contrast in PET-CT attenuation correction. In: Nuclear science symposium conference record, 2003 IEEE, vol. 3. Piscataway, NJ: IEEE, 2003; 2220-2221.
16. Wong ZT, Paulson KE, Nelson CR, Patz FE Jr, Coleman ER. Practical Approach to Diagnostic CT Combined with PET. AJR 2007; 188: 622-629.
17. Berthelsen AK, Holm S, Loft A, Klausen TL, Andersen F, Hojgaard L. PET/CT with intravenous contrast can be used for PET attenuation correction in cancer patients. Eur J Nucl Med Mol Imaging 2005; 32: 1167-1175.
18. Yau YY, Chan WS, Tam YM et al. Application of intravenous contrast in PET/CT: does it really introduce significant attenuation correction error? J Nucl Med 2005; 46: 283-291.
19. Juergens KU, Weckesser M, Stegger L et al. Tumor staging using whole-body high-resolution 16-channel PET-CT: does additional low-dose chest CT in inspiration improve the detection of solitary pulmonary nodules? Eur Radiol 2006; 16: 1131-1137.
20. Kalra MK, Maher MM, Toth TL et al. Techniques and applications of automatic tube current modulation for CT. Radiology 2004; 233: 649-657.
21. Kalra MK, Maher MM, Toth TL et al. Comparison of z-axis automatic tube current modulation technique with fixed tube current CT scanning of abdomen and pelvis. Radiology 2004; 232: 347-353.