Difference between total and intact assays for N-terminal propeptide of type I procollagen reflects degradation of pN-collagen rather than denaturation of intact propeptide

Annals of Clinical Biochemistry

Volumn 47, Issue 1, 2010, Pages 67-71

  Koivula, Marja Kaisa ^a,b   Ruotsalainen, Vesa ^c   Björkman, Mikko ^d   Nurmenniemi, Sini ^a   Ikäheimo, Risto ^a   Savolainen, Kari ^e   Sorva, Antti ^d   Risteli, Juha ^a  

^a UNIVERSITY OF OULU   (Finland)

^b TURKU UNIVERSITY HOSPITAL   (Finland)

^c Orion Diagnostica Oy   (Finland)

^d HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^e ISLAB   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO TERMINAL TELOPEPTIDE; BIOLOGICAL MARKER; COLLAGEN; COLLAGEN TYPE 1; MONOMER; N TERMINAL PROPEPTIDE OF TYPE I PROCOLLAGEN; PEPTIDE; PROPEPTIDE; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BLOOD DONOR; BLOOD SAMPLING; CHRONIC KIDNEY FAILURE; CONTROLLED STUDY; DENATURATION; FEMALE; FINLAND; FREEZE DRYING; GEL FILTRATION; GERIATRICS; HEMODIALYSIS; HOSPITAL; HUMAN; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN DETERMINATION; SERUM;

ADULT; BLOOD CHEMICAL ANALYSIS; COLLAGEN TYPE I; FEMALE; HUMANS; MALE; MIDDLE AGED; OSMOLAR CONCENTRATION; PEPTIDE FRAGMENTS; PHOSPHOPEPTIDES; PROCOLLAGEN; PROTEIN DENATURATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RENAL DIALYSIS; SPECIMEN HANDLING; YOUNG ADULT;

EID: 75149155775     PISSN: 00045632     EISSN: 00045632     Source Type: Journal    
DOI: 10.1258/acb.2009.009110     Document Type: Article

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