Activation of retinal guanylyl cyclase RetGC1 by GCAP1: Stoichiometry of binding and effect of new LCA-related mutations

Biochemistry

Volumn 49, Issue 4, 2010, Pages 709-717

  Peshenko, Igor V ^a   Olshevskaya, Elena V ^a   Yao, Suxia ^b   Ezzeldin, Hany H ^b   Pittler, Steven J ^b   Dizhoor, Alexander M ^a  

^a SALUS UNIVERSITY   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COEXPRESSED; GUANYLYL CYCLASE; HEK293 CELLS; HOMOLOGY DOMAIN; PHOTORESPONSES; WILD TYPES;

CALCIUM; LIFE CYCLE; MANGANESE; MANGANESE COMPOUNDS; OPHTHALMOLOGY; STOICHIOMETRY;

CHEMICAL ACTIVATION;

ASPARTIC ACID; CALCIUM MAGNESIUM SENSOR PROTEIN; FLUORESCENT DYE; GUANYLATE CYCLASE; GUANYLATE CYCLASE ACTIVATOR; ISOENZYME; MAGNESIUM ION; MANGANESE; PHOSPHOTRANSFERASE; RETINAL GUANYLYL CYCLASE; TYROSINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CASE REPORT; CELL LABELING; CELL STRAIN HEK293; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME BINDING; GENE MUTATION; GENETIC TRANSFECTION; HUMAN; LEBER CONGENITAL AMAUROSIS; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; RETINA DYSTROPHY; STOICHIOMETRY; WILD TYPE;

BINDING SITES; CELL LINE; ENZYME ACTIVATION; GUANYLATE CYCLASE; GUANYLATE CYCLASE-ACTIVATING PROTEINS; HUMANS; LEBER CONGENITAL AMAUROSIS; MUTATION; RETINA; TRANSFECTION;

VERTEBRATA;

EID: 75149139527     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi901495y     Document Type: Article

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