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Volumn 46, Issue 3, 2010, Pages 650-658

Antitumour activity of NK012, SN-38-incorporating polymeric micelles, in hypovascular orthotopic pancreatic tumour

Author keywords

DDS (drug delivery system); NK012; Pancreatic cancer; Polymer micelles

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; ANTINEOPLASTIC AGENT; GEMCITABINE; IRINOTECAN; NK 012; UNCLASSIFIED DRUG;

EID: 75149138953     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2009.11.014     Document Type: Article
Times cited : (28)

References (27)
  • 3
    • 0029954462 scopus 로고    scopus 로고
    • Pancreatic carcinoma in perspective. A continuing challenge
    • Wanebo H.J., and Vezeridis M.P. Pancreatic carcinoma in perspective. A continuing challenge. Cancer 78 (1996) 580-591
    • (1996) Cancer , vol.78 , pp. 580-591
    • Wanebo, H.J.1    Vezeridis, M.P.2
  • 4
    • 0028292341 scopus 로고
    • Phase II trial of gemcitabine (2,2′-difluorodeoxycytidine) in patients with adenocarcinoma of the pancreas
    • Casper E.S., Green M.R., Kelsen D.P., et al. Phase II trial of gemcitabine (2,2′-difluorodeoxycytidine) in patients with adenocarcinoma of the pancreas. Invest New Drugs 12 (1994) 29-34
    • (1994) Invest New Drugs , vol.12 , pp. 29-34
    • Casper, E.S.1    Green, M.R.2    Kelsen, D.P.3
  • 5
    • 0030049697 scopus 로고    scopus 로고
    • Phase II study of gemcitabine in patients with advanced pancreatic cancer
    • Carmichael J., Fink U., Russell R.C., et al. Phase II study of gemcitabine in patients with advanced pancreatic cancer. Br J Cancer 73 (1996) 101-105
    • (1996) Br J Cancer , vol.73 , pp. 101-105
    • Carmichael, J.1    Fink, U.2    Russell, R.C.3
  • 6
    • 34249933404 scopus 로고    scopus 로고
    • Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group
    • Moore M.J., Goldstein D., Hamm J., et al. Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol 25 (2007) 1960-1966
    • (2007) J Clin Oncol , vol.25 , pp. 1960-1966
    • Moore, M.J.1    Goldstein, D.2    Hamm, J.3
  • 7
    • 0020614669 scopus 로고
    • Dynamic CT of pancreatic tumors
    • Hosoki T. Dynamic CT of pancreatic tumors. AJR Am J Roentgenol 140 (1983) 959-965
    • (1983) AJR Am J Roentgenol , vol.140 , pp. 959-965
    • Hosoki, T.1
  • 8
    • 20444479863 scopus 로고    scopus 로고
    • Differential diagnosis of pancreatic tumors using ultrasound contrast imaging
    • Sofuni A., Iijima H., Moriyasu F., et al. Differential diagnosis of pancreatic tumors using ultrasound contrast imaging. J Gastroenterol 40 (2005) 518-525
    • (2005) J Gastroenterol , vol.40 , pp. 518-525
    • Sofuni, A.1    Iijima, H.2    Moriyasu, F.3
  • 9
    • 0022858683 scopus 로고
    • A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs
    • Matsumura Y., and Maeda H. A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res 46 (1986) 6387-6392
    • (1986) Cancer Res , vol.46 , pp. 6387-6392
    • Matsumura, Y.1    Maeda, H.2
  • 10
    • 0015451631 scopus 로고
    • Action of camptothecin on mammalian cells in culture
    • Li L.H., Fraser T.J., Olin E.J., and Bhuyan B.K. Action of camptothecin on mammalian cells in culture. Cancer Res 32 (1972) 2643-2650
    • (1972) Cancer Res , vol.32 , pp. 2643-2650
    • Li, L.H.1    Fraser, T.J.2    Olin, E.J.3    Bhuyan, B.K.4
  • 11
    • 0015044313 scopus 로고
    • Studies on the antitumor activity, mechanism of action, and cell cycle effects of camptothecin
    • Gallo R.C., Whang-Peng J., and Adamson R.H. Studies on the antitumor activity, mechanism of action, and cell cycle effects of camptothecin. J Natl Cancer Inst 46 (1971) 789-795
    • (1971) J Natl Cancer Inst , vol.46 , pp. 789-795
    • Gallo, R.C.1    Whang-Peng, J.2    Adamson, R.H.3
  • 12
  • 13
    • 0015378084 scopus 로고
    • Phase I clinical trial of weekly and daily treatment with camptothecin (NSC-100880): correlation with preclinical studies
    • Muggia F.M., Creaven P.J., Hansen H.H., Cohen M.H., and Selawry O.S. Phase I clinical trial of weekly and daily treatment with camptothecin (NSC-100880): correlation with preclinical studies. Cancer Chemother Rep 56 (1972) 515-521
    • (1972) Cancer Chemother Rep , vol.56 , pp. 515-521
    • Muggia, F.M.1    Creaven, P.J.2    Hansen, H.H.3    Cohen, M.H.4    Selawry, O.S.5
  • 14
    • 33750549679 scopus 로고    scopus 로고
    • Novel SN-38-incorporating polymeric micelles, NK012, eradicate vascular endothelial growth factor-secreting bulky tumors
    • Koizumi F., Kitagawa M., Negishi T., et al. Novel SN-38-incorporating polymeric micelles, NK012, eradicate vascular endothelial growth factor-secreting bulky tumors. Cancer Res 66 (2006) 10048-10056
    • (2006) Cancer Res , vol.66 , pp. 10048-10056
    • Koizumi, F.1    Kitagawa, M.2    Negishi, T.3
  • 15
    • 40949135609 scopus 로고    scopus 로고
    • Novel SN-38-incorporated polymeric micelle, NK012, strongly suppresses renal cancer progression
    • Sumitomo M., Koizumi F., Asano T., et al. Novel SN-38-incorporated polymeric micelle, NK012, strongly suppresses renal cancer progression. Cancer Res 68 (2008) 1631-1635
    • (2008) Cancer Res , vol.68 , pp. 1631-1635
    • Sumitomo, M.1    Koizumi, F.2    Asano, T.3
  • 16
    • 40749107087 scopus 로고    scopus 로고
    • Synergistic antitumor activity of the novel SN-38-incorporating polymeric micelles, NK012, combined with 5-fluorouracil in a mouse model of colorectal cancer, as compared with that of irinotecan plus 5-fluorouracil
    • Nakajima T.E., Yasunaga M., Kano Y., et al. Synergistic antitumor activity of the novel SN-38-incorporating polymeric micelles, NK012, combined with 5-fluorouracil in a mouse model of colorectal cancer, as compared with that of irinotecan plus 5-fluorouracil. Int J Cancer 122 (2008) 2148-2153
    • (2008) Int J Cancer , vol.122 , pp. 2148-2153
    • Nakajima, T.E.1    Yasunaga, M.2    Kano, Y.3
  • 17
    • 56449127975 scopus 로고    scopus 로고
    • Antitumor effect of SN-38-releasing polymeric micelles, NK012, on spontaneous peritoneal metastases from orthotopic gastric cancer in mice compared with irinotecan
    • Nakajima T.E., Yanagihara K., Takigahira M., et al. Antitumor effect of SN-38-releasing polymeric micelles, NK012, on spontaneous peritoneal metastases from orthotopic gastric cancer in mice compared with irinotecan. Cancer Res 68 (2008) 9318-9322
    • (2008) Cancer Res , vol.68 , pp. 9318-9322
    • Nakajima, T.E.1    Yanagihara, K.2    Takigahira, M.3
  • 18
    • 64249091937 scopus 로고    scopus 로고
    • Potent antitumor effect of SN-38-incorporating polymeric micelle, NK012, against malignant glioma
    • Kuroda J.I., Kuratsu J.I., Yasunaga M., Koga Y., Saito Y., and Matsumura Y. Potent antitumor effect of SN-38-incorporating polymeric micelle, NK012, against malignant glioma. Int J Cancer 124 (2009) 2505-2511
    • (2009) Int J Cancer , vol.124 , pp. 2505-2511
    • Kuroda, J.I.1    Kuratsu, J.I.2    Yasunaga, M.3    Koga, Y.4    Saito, Y.5    Matsumura, Y.6
  • 19
    • 43549107330 scopus 로고    scopus 로고
    • Enhanced distribution of NK012, a polymeric micelle-encapsulated SN-38, and sustained release of SN-38 within tumors can beat a hypovascular tumor
    • Saito Y., Yasunaga M., Kuroda J., Koga Y., and Matsumura Y. Enhanced distribution of NK012, a polymeric micelle-encapsulated SN-38, and sustained release of SN-38 within tumors can beat a hypovascular tumor. Cancer Sci 99 (2008) 1258-1264
    • (2008) Cancer Sci , vol.99 , pp. 1258-1264
    • Saito, Y.1    Yasunaga, M.2    Kuroda, J.3    Koga, Y.4    Matsumura, Y.5
  • 20
    • 33751000765 scopus 로고    scopus 로고
    • Combination therapy using gemcitabine and radioimmunotherapy in nude mice with small peritoneal metastases of colonic origin
    • Koppe M.J., Oyen W.J., Bleichrodt R.P., Verhofstad A.A., Goldenberg D.M., and Boerman O.C. Combination therapy using gemcitabine and radioimmunotherapy in nude mice with small peritoneal metastases of colonic origin. Cancer Biother Radiopharm 21 (2006) 506-514
    • (2006) Cancer Biother Radiopharm , vol.21 , pp. 506-514
    • Koppe, M.J.1    Oyen, W.J.2    Bleichrodt, R.P.3    Verhofstad, A.A.4    Goldenberg, D.M.5    Boerman, O.C.6
  • 21
    • 0001577078 scopus 로고
    • Doxorubicin conjugated with a monoclonal antibody directed to a human melanoma-associated proteoglycan suppresses the growth of established tumor xenografts in nude mice
    • Yang H.M., and Reisfeld R.A. Doxorubicin conjugated with a monoclonal antibody directed to a human melanoma-associated proteoglycan suppresses the growth of established tumor xenografts in nude mice. Proc Natl Acad Sci USA 85 (1988) 1189-1193
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 1189-1193
    • Yang, H.M.1    Reisfeld, R.A.2
  • 22
    • 0025996996 scopus 로고
    • Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11
    • Kawato Y., Aonuma M., Hirota Y., Kuga H., and Sato K. Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11. Cancer Res 51 (1991) 4187-4191
    • (1991) Cancer Res , vol.51 , pp. 4187-4191
    • Kawato, Y.1    Aonuma, M.2    Hirota, Y.3    Kuga, H.4    Sato, K.5
  • 23
    • 0035286282 scopus 로고    scopus 로고
    • Liposomal encapsulated anthracyclines: new therapeutic horizons
    • Muggia F.M. Liposomal encapsulated anthracyclines: new therapeutic horizons. Curr Oncol Rep 3 (2001) 156-162
    • (2001) Curr Oncol Rep , vol.3 , pp. 156-162
    • Muggia, F.M.1
  • 24
    • 6344269434 scopus 로고    scopus 로고
    • Quantitative assessment of tumor vasculature and response to therapy in kaposi's sarcoma using functional noninvasive imaging
    • Hassan M., Little R.F., Vogel A., et al. Quantitative assessment of tumor vasculature and response to therapy in kaposi's sarcoma using functional noninvasive imaging. Technol Cancer Res Treat 3 (2004) 451-457
    • (2004) Technol Cancer Res Treat , vol.3 , pp. 451-457
    • Hassan, M.1    Little, R.F.2    Vogel, A.3
  • 25
    • 0032169020 scopus 로고    scopus 로고
    • The blood flow characteristics in borderline ovarian tumors based on both color Doppler ultrasound and histopathological analyses
    • Emoto M., Udo T., Obama H., Eguchi F., Hachisuga T., and Kawarabayashi T. The blood flow characteristics in borderline ovarian tumors based on both color Doppler ultrasound and histopathological analyses. Gynecol Oncol 70 (1998) 351-357
    • (1998) Gynecol Oncol , vol.70 , pp. 351-357
    • Emoto, M.1    Udo, T.2    Obama, H.3    Eguchi, F.4    Hachisuga, T.5    Kawarabayashi, T.6
  • 26
    • 75149186342 scopus 로고    scopus 로고
    • Kato K, Hamaguchi T, Shirao K et al. Interim analysis of phase I study of NK012, polymer micelle SN-38, in patients with advanced cancer. Proc Am Soc Clin Oncol GI 2008 [Abs #485].
    • Kato K, Hamaguchi T, Shirao K et al. Interim analysis of phase I study of NK012, polymer micelle SN-38, in patients with advanced cancer. Proc Am Soc Clin Oncol GI 2008 [Abs #485].


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.