Can the prevalence of high blood drug concentrations in a population be estimated by analysing oral fluid? A study of tetrahydrocannabinol and amphetamine

Forensic Science International

Volumn 195, Issue 1-3, 2010, Pages 153-159

  Gjerde, Hallvard ^a   Verstraete, Alain ^b  

^a NORWEGIAN INSTITUTE OF PUBLIC HEALTH   (Norway)

^b GHENT UNIVERSITY   (Belgium)

Author keywords

Amphetamine; Blood; Linear regression; Monte Carlo simulation; Oral fluid; Population; Prevalence; Tetrahydrocannabinol

Indexed keywords

AMPHETAMINE; TETRAHYDROCANNABINOL;

ACCURACY; ARTICLE; CANNABIS SMOKING; CONTROLLED STUDY; DRUG ABUSE; DRUG BLOOD LEVEL; DRUG SALIVA LEVEL; HUMAN; INTERMETHOD COMPARISON; MATHEMATICAL COMPUTING; MONTE CARLO METHOD; POPULATION RESEARCH; PREVALENCE; PRIORITY JOURNAL; SALIVA ANALYSIS; SENSITIVITY ANALYSIS;

EID: 75049085265     PISSN: 03790738     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.forsciint.2009.12.011     Document Type: Article

References (20)

1. Spiehler V. Drugs in saliva. In: Moffat A.C., Osselton M.D., and Widdop B. (Eds). Clarke's Analysis of Drugs and Poisons. 3rd ed. (2004), Pharmaceutical Press, London 109-123
2. Cone E.J. Legal, workplace, and treatment drug testing with alternate biological matrices on a global scale. Forensic Sci. Int. 121 (2001) 7-15
3. Caplan Y.H., and Goldberger B.A. Alternative specimens for workplace drug testing. J. Anal. Toxicol. 25 (2001) 396-399
4. Choo R.E., and Huestis M.A. Oral fluid as a diagnostic tool. Clin. Chem. Lab. Med. 42 (2004) 1273-1287
5. Samyn N., Verstraete A., van Haeren C., and Kintz P. Analysis of drugs of abuse in saliva. Forensic Sci. Rev. 11 (1999) 2-17
6. Øiestad E.L., Johansen U., and Christophersen A.S. Drug screening of preserved oral fluid by liquid chromatography-tandem mass spectrometry. Clin. Chem. 53 (2007) 300-309
7. Langel K., Engblom C., Pehrsson A., Gunnar T., Ariniemi K., and Lillsunde P. Drug testing in oral fluid-evaluation of sample collection devices. J. Anal. Toxicol. 32 (2008) 393-401
8. Crouch D.J. Oral fluid collection: the neglected variable in oral fluid testing. Forensic Sci. Int. 150 (2005) 165-173
9. Wille S.M.R., Raes E., Lillsunde P., Gunnar T., Laloup M., Samyn N., Christophersen A.S., Moeller M.R., Hammer K.P., and Verstraete A. Relationship between oral fluid and blood concentrations of drugs of abuse in drivers suspected of DUID. Ther. Drug Monit. 31 (2009) 511-519
10. Giles H.G., Miller R., Macleod S.M., and Sellers E.M. Diazepam and N-desmethyldiazepam in saliva of hospital inpatients. J. Clin. Pharmacol. 20 (1980) 71-76
11. Engblom C., Gunnar T., Rantanen A., and Lillsunde P. Driving under the influence of drugs - amphetamine concentrations in oral fluid and whole blood samples. J. Anal. Toxicol. 31 (2007) 276-280
12. Ramaekers J.G., Moeller M.R., van Ruitenbeek P., Theunissen E.L., Schneider E., and Kauert G. Cognition and motor control as a function of Delta9-THC concentration in serum and oral fluid: limits of impairment. Drug Alcohol Depend. 85 (2006) 114-122
13. Kato K., Hillsgrove M., Weinhold L., Gorelick D.A., Darwin W.D., and Cone E.J. Cocaine and metabolite excretion in saliva under stimulated and nonstimulated conditions. J. Anal. Toxicol. 17 (1993) 338-341
14. Schepers R.J., Oyler J.M., Joseph Jr. R.E., Cone E.J., Moolchan E.T., and Huestis M.A. Methamphetamine and amphetamine pharmacokinetics in oral fluid and plasma after controlled oral methamphetamine administration to human volunteers. Clin. Chem. 49 (2003) 121-132
15. O'Neal C.L., Crouch D.J., Rollins D.E., and Fatah A.A. The effects of collection methods on oral fluid codeine concentrations. J. Anal. Toxicol. 24 (2000) 536-542
16. Verstraete A.G., and Raes E. In: Verstraete A.G., and Raes E. (Eds). Rosita-2 Project - Final Report (2006), Academia Press, Ghent
17. Gjerde H., Normann P.T., Pettersen B.S., Assum T., Aldrin M., Johansen U., Kristoffersen L., Øiestad E.L., Christophersen A.S., and Mørland J. Prevalence of alcohol and drugs among Norwegian motor vehicle drivers: a roadside survey. Accid. Anal. Prev. 40 (2008) 1765-1772
18. Metropolis N., and Ulam S. The Monte Carlo method. J. Am. Stat. Assoc. 44 (1949) 335-341
19. Amar J.G. The Monte Carlo method in science and engineering. Comp. Sci. Eng. 8 (2006) 9-19
20. Bonate P.L. A brief introduction to Monte Carlo simulation. Clin. Pharmacokinet. 40 (2001) 15-22