Free your MIND and the rest will follow: Decoding delirium in the intensive care unit

Critical Care Medicine

Volumn 38, Issue 2, 2010, Pages 697-698

  Balas, Michele C ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Antipsychotics; Critical care; Delirium; Haloperidol; Intensive care; Ziprasidone

Indexed keywords

HALOPERIDOL; PLACEBO; ZIPRASIDONE;

AKATHISIA; CLINICAL TRIAL; DELIRIUM; DRUG EFFICACY; EDITORIAL; HUMAN; INTENSIVE CARE; INTENSIVE CARE UNIT; LENGTH OF STAY; PRIORITY JOURNAL; QT PROLONGATION; TREATMENT OUTCOME;

EID: 74949138119     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e3181c89542     Document Type: Editorial

References (17)

1. Lin SM, Liu CY, Wang CH, et al: The impact of delirium on the survival of mechanically ventilated patients. Crit Care Med 2004; 32: 2254-2259
2. Ely EW, Inouye SK, Bernard GR, et al: Delirium in mechanically ventilated patients: Validity and reliability of the confusion assessment method for the intensive care unit (CAM-ICU). JAMA 2001; 286:2703-2710
3. Aldemir M, Ozen S, Kara IH, et al: Predisposing factors for delirium in the surgical intensive care unit. Critical Care (London) 2001; 5:265-270
4. Ely EW, Shintani A, Truman B, et al: Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit. JAMA 2004; 291:1753-1762
5. Ely EW, Gautam S, Margolin R, et al: The impact of delirium in the intensive care unit on hospital length of stay. Intensive Care Med 2001; 27:1892-1900
6. Kishi Y, Iwasaki Y, Takezawa K, et al: Delirium in critical care unit patients admitted through an emergency room. Gen Hos Psych 1995; 17:371-379
7. Milbrandt EB, Deppen S, Harrison PL, et al: Costs associated with delirium in mechanically ventilated patients. Crit Care Med 2004; 32:955-962
8. Aakerlund LP, Rosenberg J: Postoperative delirium: Treatment with supplementary oxygen. Br J Anesthesia 1994; 72:286-290
9. Ely EW, Margolin R, Francis J, et al: Evaluation of delirium in critically ill patients: Validation of the Confusion Assessment Method for the intensive care unit (CAM-ICU). Crit Care Med 2001; 29:1370-1379 (Pubitemid 32641799)
10. Dubois MJ, Bergeron N, Dumont M, et al: Delirium in an intensive care unit: A study of risk factors. Intensive Care Med 2001; 27: 1297-1304
11. Balas MC, Happ MB, Yang W, et al: Outcomes associated with delirium in older patients in surgical ICUS. Chest 2009; 135:18-25
12. Pandharipaned P, Costabile S, Cotton B, et al: Prevalence of delirium in surgical ICU patients. Crit Care Med 2005; 33A45
13. Girard TD, Pandharipande PP, Carson SS, et al: Feasibility, efficacy, and safety of antipsy-chotics for intensive care unit delirium: The MIND randomized, placebo-controlled trial. Crit Care Med 2010; 38:428-437
14. American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders. 4th ed. Washington, DC, 1994
15. Schneider LS, Tarior PN, Dagerman KS, et al: Effectiveness of atypical antipsychotic drugs in patients with Alzheimer's disease. N Engl J Med 2006; 355:1525-1538
16. Happ MB: Communicating with mechanically ventilated patients in the ICU: State of the science. AACN Clin Issues 2001; 12: 247-258
17. Inouye SK, Bogardus ST, Charpentier PA, et al: A Multicomponent intervention to prevent delirium in hospitalized older adults. N Engl J Med 1999; 340:669-676