Reducing the risk of fractures with calcium and vitamin D

BMJ (Online)

Volumn 340, Issue 7738, 2010, Pages 109-

  Sahota, Opinder ^a  

^a QUEEN S MEDICAL CENTRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

25 HYDROXYVITAMIN D; CALCIUM; COLECALCIFEROL; ERGOCALCIFEROL; VITAMIN D;

CLINICAL PRACTICE; CLINICAL TRIAL; COMBINATION CHEMOTHERAPY; DOSE RESPONSE; DRUG DOSE REGIMEN; DRUG EFFECT; DRUG EFFICACY; DRUG MEGADOSE; DRUG POTENCY; EDITORIAL; FALL RISK; FRACTURE; HIP FRACTURE; HUMAN; LOW DRUG DOSE; MONOTHERAPY; MUSCLE FUNCTION; MUSCLE STRENGTH; OUTCOME ASSESSMENT; PATIENT COMPLIANCE; PRIORITY JOURNAL; RISK FACTOR; RISK REDUCTION; TREATMENT OUTCOME; VITAMIN BLOOD LEVEL; VITAMIN SUPPLEMENTATION;

BONE DENSITY CONSERVATION AGENTS; CALCIUM; DRUG THERAPY, COMBINATION; FRACTURES, BONE; HUMANS; RISK FACTORS; VITAMIN D;

EID: 74949131563     PISSN: None     EISSN: 17561833     Source Type: Journal    
DOI: 10.1136/bmj.b5492     Document Type: Editorial

References (12)

1. Sahota O. Calcium and vitamin d reduces falls and fractures-confusion and controversy. J Nutr Health Aging 2007;11:176-8.[Web of Science][Medline]
2. Boonen S, Lips P, Bouillon R, Bischoff-Ferrari HA, Vanderschueren D, Haentjens P. Need for additional calcium to reduce the risk of hip fracture with vitamin d supplementation: evidence from a comparative meta analysis of randomised controlled trials. J Clin Endocrinol Metab 2007;92:1415-23. [Abstract/Free Full Text]
3. DIPART (vitamin D Individual Patient Analysis of Randomized Trials) Group. Patient level pooled analysis of 68 500 patients from seven major vitamin D fracture trials in US and Europe. BMJ 2009;339:b5463.
4. Avenell A, Gillespie WJ, Gillespie LD, O'Connell D. Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post menopausal osteoporosis. Cochrane Database Syst Rev 2009;(2):CD000227.
5. Chapuy MC, Arlot ME, Duboeuf F, Brun J, Crouzet B, Arnaud S, et al. Vitamin D3 and calcium prevent hip fractures in elderly women. N Engl J Med 1992;327:1637-42.[Abstract]
6. Bischoff-Ferrari HA, Willett WC, Wong JB, Stuck AE, Staehelin HB, Orav EJ, et al. Prevention of nonvertebral fractures with oral vitamin D and dose dependency a meta-analysis of randomized controlled trials. Arch Intern Med 2009;169:551-61.[Abstract/Free Full Text]
7. 3 in humans. J Clin Endocrinol Metab 2004;89:5387-91.[Abstract/Free Full Text]
8. Dawson-Hughes B, Heaney RP, Holick MF, Lips P, Meunier PJ, Vieth R. Estimates of optimal vitamin D status. Osteoporos Int 2005;16:713-6.[CrossRef][Web of Science][Medline]
9. Cavalier E, Rozet E, Gadisseur R, Carlisi A, Monge M, Chapelle JP, et al. Measurement uncertainty of 25-OH vitamin D determination with different commercially available kits: impact on the clinical cut offs. Osteoporos Int 2009; Online 9 September.
10. Glerup H, Mikkelsen K, Poulsen L, Hass E, Overbeck S, Andersen H, et al. Hypovitaminosis D myopathy without biochemical signs of osteomalacic bone involvement. Calcif Tissue Int 2000;66:419-24.[CrossRef][Web of Science][Medline]
11. Bischoff-Ferrari HA, Dawson-Hughes B, Staehelin HB, Orav JE, Stuck AE, Theiler R, et al. Fall prevention with supplemental and active forms of vitamin D: meta-analysis of randomised controlled trials. BMJ 2009;339:b3692.[Abstract/Free Full Text]
12. Pfeifer M, Begerow B, Minne HW, Suppan K, Fahrleitner-Pammer A, Dobnig H. Effects of long-term vitamin D and calcium supplementation on falls and parameters of muscle function in community-dwelling older individuals. Osteoporosis Int 2009;20:315-22.[CrossRef][Web of Science][Medline]