메뉴 건너뛰기




Volumn 27, Issue 36, 2009, Pages 6229-6236

Phase II study of preoperative gefitinib in clinical stage I non-small-cell lung cancer

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; GEFITINIB; TRANSFORMING GROWTH FACTOR ALPHA; ANTINEOPLASTIC AGENT; PROTEIN KINASE INHIBITOR; QUINAZOLINE DERIVATIVE;

EID: 74949129970     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2009.22.3370     Document Type: Article
Times cited : (92)

References (68)
  • 1
    • 49049109683 scopus 로고    scopus 로고
    • Lung adjuvant cisplatin evaluation: A pooled analysis by the LACE Collaborative Group
    • Pignon JP, Tribodet H, Scagliotti GV, et al: Lung adjuvant cisplatin evaluation: A pooled analysis by the LACE Collaborative Group. J Clin Oncol 26:3552-3559, 2008
    • (2008) J Clin Oncol , vol.26 , pp. 3552-3559
    • Pignon, J.P.1    Tribodet, H.2    Scagliotti, G.V.3
  • 2
    • 28144437799 scopus 로고    scopus 로고
    • Phase II study of neoadjuvant chemotherapy with gemcitabine and vinorelbine in resectable non-small cell lung cancer
    • Ramnath N, Sommers E, Robinson L, et al: Phase II study of neoadjuvant chemotherapy with gemcitabine and vinorelbine in resectable non-small cell lung cancer. Chest 128:3467-3474, 2005
    • (2005) Chest , vol.128 , pp. 3467-3474
    • Ramnath, N.1    Sommers, E.2    Robinson, L.3
  • 3
    • 33846794665 scopus 로고    scopus 로고
    • A systematic review and meta-analysis of the literature: Chemotherapy and surgery versus surgery alone in non-small cell lung cancer
    • Burdett S, Stewart LA, Rydzewska L: A systematic review and meta-analysis of the literature: Chemotherapy and surgery versus surgery alone in non-small cell lung cancer. J Thorac Oncol 1:611-621, 2006
    • (2006) J Thorac Oncol , vol.1 , pp. 611-621
    • Burdett, S.1    Stewart, L.A.2    Rydzewska, L.3
  • 4
    • 0036139728 scopus 로고    scopus 로고
    • Depierre A, Milleron B, Moro-Sibilot D, et al: Preoperative chemotherapy followed by surgery compared with primary surgery in resectable stage I (except T1N0), II, and IIIa non-small-cell lung cancer. J Clin Oncol 20:247-253, 2002
    • Depierre A, Milleron B, Moro-Sibilot D, et al: Preoperative chemotherapy followed by surgery compared with primary surgery in resectable stage I (except T1N0), II, and IIIa non-small-cell lung cancer. J Clin Oncol 20:247-253, 2002
  • 5
    • 37549001399 scopus 로고    scopus 로고
    • Neoadjuvant chemotherapy with gemcitabine-containing regimens in patients with early-stage non-small cell lung cancer
    • Detterbeck FC, Socinska MA, Gralla RJ, et al: Neoadjuvant chemotherapy with gemcitabine-containing regimens in patients with early-stage non-small cell lung cancer. J Thorac Oncol 3:37-45, 2008
    • (2008) J Thorac Oncol , vol.3 , pp. 37-45
    • Detterbeck, F.C.1    Socinska, M.A.2    Gralla, R.J.3
  • 6
    • 58949097480 scopus 로고    scopus 로고
    • Clinical efficacy and predictive molecular markers of neoadjuvant gemcitabine and pemetrexed in resectable non-small cell lung cancer
    • Bepler G, Sommers KE, Cantor A, et al: Clinical efficacy and predictive molecular markers of neoadjuvant gemcitabine and pemetrexed in resectable non-small cell lung cancer. J Thorac Oncol 3:1112-1118, 2008
    • (2008) J Thorac Oncol , vol.3 , pp. 1112-1118
    • Bepler, G.1    Sommers, K.E.2    Cantor, A.3
  • 7
    • 84871473694 scopus 로고    scopus 로고
    • Scagliotti GV, Pastorino U, Vansteenkiste JF, et al: A phase III randomized study of surgery alone or surgery plus preoperative gemcitabine-cisplatin in early-stage non-small cell lung cancer (NSCLC): Follow-up data of Ch.E.S.T. J Clin Oncol 26:399s, 2008 (suppl; abstr 7508)
    • Scagliotti GV, Pastorino U, Vansteenkiste JF, et al: A phase III randomized study of surgery alone or surgery plus preoperative gemcitabine-cisplatin in early-stage non-small cell lung cancer (NSCLC): Follow-up data of Ch.E.S.T. J Clin Oncol 26:399s, 2008 (suppl; abstr 7508)
  • 8
    • 33746789922 scopus 로고    scopus 로고
    • Prospective phase II study of gefitinib for chemotherapy-naïve patients with advanced non-small-cell lung cancer with epidermal growth factor receptor gene mutations
    • Inoue A, Suzuki T, Fukuhara T, et al: Prospective phase II study of gefitinib for chemotherapy-naïve patients with advanced non-small-cell lung cancer with epidermal growth factor receptor gene mutations. J Clin Oncol 24:3340-3346, 2006
    • (2006) J Clin Oncol , vol.24 , pp. 3340-3346
    • Inoue, A.1    Suzuki, T.2    Fukuhara, T.3
  • 9
    • 33750205340 scopus 로고    scopus 로고
    • A phase II trial of gefitinib as first-line therapy for advanced non-small cell lung cancer with epidermal growth factor receptor mutations
    • Asahina H, Yamazaki K, Kinoshita I, et al: A phase II trial of gefitinib as first-line therapy for advanced non-small cell lung cancer with epidermal growth factor receptor mutations. Br J Cancer 95: 998-1004, 2006
    • (2006) Br J Cancer , vol.95 , pp. 998-1004
    • Asahina, H.1    Yamazaki, K.2    Kinoshita, I.3
  • 10
    • 65549154268 scopus 로고    scopus 로고
    • Randomized phase II study of gefitinib compared with placebo in chemotherapy-naive patients with advanced non-small-cell lung cancer and poor performance status
    • Goss G, Ferry D, Wierzbicki R, et al: Randomized phase II study of gefitinib compared with placebo in chemotherapy-naive patients with advanced non-small-cell lung cancer and poor performance status. J Clin Oncol 27:2253-2260, 2009
    • (2009) J Clin Oncol , vol.27 , pp. 2253-2260
    • Goss, G.1    Ferry, D.2    Wierzbicki, R.3
  • 11
    • 52049096854 scopus 로고    scopus 로고
    • Gefitinib versus vinorelbine in chemotherapy-naive elderly patients with advanced non-small-cell lung cancer (INVITE): A randomized, phase II study
    • Crinò L, Cappuzzo F, Zatloukal P, et al: Gefitinib versus vinorelbine in chemotherapy-naive elderly patients with advanced non-small-cell lung cancer (INVITE): A randomized, phase II study. J Clin Oncol 26:4253-4260, 2008
    • (2008) J Clin Oncol , vol.26 , pp. 4253-4260
    • Crinò, L.1    Cappuzzo, F.2    Zatloukal, P.3
  • 12
    • 0142055937 scopus 로고    scopus 로고
    • Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: A randomized trial
    • Kris MG, Natale RB, Herbst RS, et al: Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: A randomized trial. JAMA 290:2149-2158, 2003
    • (2003) JAMA , vol.290 , pp. 2149-2158
    • Kris, M.G.1    Natale, R.B.2    Herbst, R.S.3
  • 13
    • 27544503230 scopus 로고    scopus 로고
    • Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small cell lung cancer: Results from a randomized, placebo-controlled, multicenter study (Iressa Survival Evaluation in Lung Cancer)
    • Thatcher N, Chang A, Parikh P, et al: Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small cell lung cancer: Results from a randomized, placebo-controlled, multicenter study (Iressa Survival Evaluation in Lung Cancer). Lancet 366:1527-1537, 2005
    • (2005) Lancet , vol.366 , pp. 1527-1537
    • Thatcher, N.1    Chang, A.2    Parikh, P.3
  • 14
    • 1842509828 scopus 로고    scopus 로고
    • Bronchioloalveolar pathologic subtype and smoking history predict sensitivity to gefitinib in advanced non-small-cell lung cancer
    • Miller VA, Kris MG, Shah N, et al: Bronchioloalveolar pathologic subtype and smoking history predict sensitivity to gefitinib in advanced non-small-cell lung cancer. J Clin Oncol 22:1103-1109, 2004
    • (2004) J Clin Oncol , vol.22 , pp. 1103-1109
    • Miller, V.A.1    Kris, M.G.2    Shah, N.3
  • 15
    • 34047132314 scopus 로고    scopus 로고
    • Combination of EGFR gene copy number and protein expression predicts outcome for advanced non-small-cell lung cancer patients treated with gefitinib
    • Hirsch FR, Varella-Garcia M, Cappuzzo F, et al: Combination of EGFR gene copy number and protein expression predicts outcome for advanced non-small-cell lung cancer patients treated with gefitinib. Ann Oncol 18:752-760, 2007
    • (2007) Ann Oncol , vol.18 , pp. 752-760
    • Hirsch, F.R.1    Varella-Garcia, M.2    Cappuzzo, F.3
  • 16
    • 27244451321 scopus 로고    scopus 로고
    • Epidermal growth factor receptor gene mutations and increase copy numbers predict gefitinib sensitivity in patients with recurrent non-small-cell lung cancer
    • Takano T, Ohe Y, Sakamoto H, et al: Epidermal growth factor receptor gene mutations and increase copy numbers predict gefitinib sensitivity in patients with recurrent non-small-cell lung cancer. J Clin Oncol 23:6829-6837, 2005
    • (2005) J Clin Oncol , vol.23 , pp. 6829-6837
    • Takano, T.1    Ohe, Y.2    Sakamoto, H.3
  • 17
    • 56249109644 scopus 로고    scopus 로고
    • Gefitinib versus docetaxel in previously treated non-small-cell lung cancer (INTEREST): A randomised phase III trial
    • Kim ES, Hirsh V, Mok T, et al: Gefitinib versus docetaxel in previously treated non-small-cell lung cancer (INTEREST): A randomised phase III trial. Lancet 372:1809-1818, 2008
    • (2008) Lancet , vol.372 , pp. 1809-1818
    • Kim, E.S.1    Hirsh, V.2    Mok, T.3
  • 18
    • 52049125250 scopus 로고    scopus 로고
    • Phase III study, V-15-32, of gefitinib versus docetaxel in previously treated Japanese patients with non-small-cell lung cancer
    • Maruyama R, Nishiwaki Y, Tamura T, et al: Phase III study, V-15-32, of gefitinib versus docetaxel in previously treated Japanese patients with non-small-cell lung cancer. J Clin Oncol 26:4244-4252, 2008
    • (2008) J Clin Oncol , vol.26 , pp. 4244-4252
    • Maruyama, R.1    Nishiwaki, Y.2    Tamura, T.3
  • 19
    • 65749109060 scopus 로고    scopus 로고
    • The role of epidermal growth factor receptor tyrosine kinase inhibitors as therapy for advanced, metastatic, and recurrent non-small cell lung cancer: A Canadian national consensus statement
    • Ellis PM, Morzycki W, Melosky B, et al: The role of epidermal growth factor receptor tyrosine kinase inhibitors as therapy for advanced, metastatic, and recurrent non-small cell lung cancer: A Canadian national consensus statement. Curr Oncol 16:27-48, 2009
    • (2009) Curr Oncol , vol.16 , pp. 27-48
    • Ellis, P.M.1    Morzycki, W.2    Melosky, B.3
  • 20
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors: European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada
    • Therasse P, Arbuck SG, Eisenhauer EA, et al: New guidelines to evaluate the response to treatment in solid tumors: European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 92:205-216, 2000
    • (2000) J Natl Cancer Inst , vol.92 , pp. 205-216
    • Therasse, P.1    Arbuck, S.G.2    Eisenhauer, E.A.3
  • 21
    • 55549138045 scopus 로고    scopus 로고
    • Adjuvant paclitaxel plus carboplatin compared with observation in stage IB non-small-cell lung cancer: CALGB 9633 with the Cancer and Leukemia Group B, Radiation Therapy Oncology Group, and North Central Cancer Treatment Group Study Groups
    • Strauss GM, Herndon JE 2nd, Maddaus MA, et al: Adjuvant paclitaxel plus carboplatin compared with observation in stage IB non-small-cell lung cancer: CALGB 9633 with the Cancer and Leukemia Group B, Radiation Therapy Oncology Group, and North Central Cancer Treatment Group Study Groups. J Clin Oncol 26:5043-5051, 2008
    • (2008) J Clin Oncol , vol.26 , pp. 5043-5051
    • Strauss, G.M.1    Herndon 2nd, J.E.2    Maddaus, M.A.3
  • 22
    • 33747847740 scopus 로고    scopus 로고
    • Adjuvant vinorelbine plus cisplatin versus observation in patients with completely resected stage IB-IIIA non-small-cell lung cancer (Adjuvant Navelbine International Trialist Association [ANITA]): A randomised controlled trial
    • Douillard JY, Rosell R, De Lena M, et al: Adjuvant vinorelbine plus cisplatin versus observation in patients with completely resected stage IB-IIIA non-small-cell lung cancer (Adjuvant Navelbine International Trialist Association [ANITA]): A randomised controlled trial. Lancet Oncol 7:719-727, 2006
    • (2006) Lancet Oncol , vol.7 , pp. 719-727
    • Douillard, J.Y.1    Rosell, R.2    De Lena, M.3
  • 23
    • 20544455590 scopus 로고    scopus 로고
    • Vinorelbine plus cisplatin vs. observation in resected non-small-cell lung cancer
    • Winton T, Livingston R, Johnson D, et al: Vinorelbine plus cisplatin vs. observation in resected non-small-cell lung cancer. N Engl J Med 352:2589-2597, 2005
    • (2005) N Engl J Med , vol.352 , pp. 2589-2597
    • Winton, T.1    Livingston, R.2    Johnson, D.3
  • 24
    • 33747820148 scopus 로고    scopus 로고
    • Lung Adjuvant Cisplatin Evaluation (LACE): A pooled analysis of five randomized clinical trials including 4584 patients
    • suppl; abstr 7008, 366s
    • Pignon JP, Tribodet H, Scagliotti GV, et al: Lung Adjuvant Cisplatin Evaluation (LACE): A pooled analysis of five randomized clinical trials including 4584 patients. J Clin Oncol 24:366s, 2006 (suppl; abstr 7008)
    • (2006) J Clin Oncol , vol.24
    • Pignon, J.P.1    Tribodet, H.2    Scagliotti, G.V.3
  • 25
    • 22044453790 scopus 로고    scopus 로고
    • Erlotinib in lung cancer: Molecular and clinical predictors of outcome
    • Tsao MS, Sakurada A, Cutz JC, et al: Erlotinib in lung cancer: Molecular and clinical predictors of outcome. N Engl J Med 353:133-144, 2005
    • (2005) N Engl J Med , vol.353 , pp. 133-144
    • Tsao, M.S.1    Sakurada, A.2    Cutz, J.C.3
  • 26
    • 20444498630 scopus 로고    scopus 로고
    • Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small cell lung cancer
    • Cappuzzo F, Hirsch FR, Rossi E, et al: Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small cell lung cancer. J Natl Cancer Inst 97:643-655, 2005
    • (2005) J Natl Cancer Inst , vol.97 , pp. 643-655
    • Cappuzzo, F.1    Hirsch, F.R.2    Rossi, E.3
  • 27
    • 23844544647 scopus 로고    scopus 로고
    • Rapid polymerase chain reaction-based detection of epidermal growth factor receptor gene mutations in lung adenocarcinomas
    • Pan QPW, Ladanyi M: Rapid polymerase chain reaction-based detection of epidermal growth factor receptor gene mutations in lung adenocarcinomas. J Mol Diagn 7:396-403, 2005
    • (2005) J Mol Diagn , vol.7 , pp. 396-403
    • Pan, Q.P.W.1    Ladanyi, M.2
  • 28
    • 34249977180 scopus 로고    scopus 로고
    • Compliance of adjuvant chemotherapy in non-small cell lung cancer (NSCLC); no longer an issue
    • suppl; abstr 7154, 402s
    • Aljubran A, Leighl N, Pintilie M, et al: Compliance of adjuvant chemotherapy in non-small cell lung cancer (NSCLC); no longer an issue. J Clin Oncol 24:402s, 2006 (suppl; abstr 7154)
    • (2006) J Clin Oncol , vol.24
    • Aljubran, A.1    Leighl, N.2    Pintilie, M.3
  • 29
    • 0141651877 scopus 로고    scopus 로고
    • Scagliotti GV, Fossati R, Torri V, et al: Randomized study of adjuvant chemotherapy for completely resected stage I, II, or IIIA non-small-cell lung cancer. J Natl Cancer Inst 95:1422-1424, 2003
    • Scagliotti GV, Fossati R, Torri V, et al: Randomized study of adjuvant chemotherapy for completely resected stage I, II, or IIIA non-small-cell lung cancer. J Natl Cancer Inst 95:1422-1424, 2003
  • 30
    • 0346238665 scopus 로고    scopus 로고
    • Cisplatin-based adjuvant chemotherapy in patients with completely resected non-small-cell lung cancer
    • Arriagada R, Bergman B, Dunant A, et al: Cisplatin-based adjuvant chemotherapy in patients with completely resected non-small-cell lung cancer. N Engl J Med 350:351-360, 2004
    • (2004) N Engl J Med , vol.350 , pp. 351-360
    • Arriagada, R.1    Bergman, B.2    Dunant, A.3
  • 31
    • 34249704163 scopus 로고    scopus 로고
    • Referral patterns for adjuvant chemotherapy in patients with completely resected non-small cell lung cancer
    • Kassam F, Shepherd FA, Johnston M, et al: Referral patterns for adjuvant chemotherapy in patients with completely resected non-small cell lung cancer. J Thorac Oncol 2:39-43, 2007
    • (2007) J Thorac Oncol , vol.2 , pp. 39-43
    • Kassam, F.1    Shepherd, F.A.2    Johnston, M.3
  • 32
    • 34249866544 scopus 로고    scopus 로고
    • Preoperative chemotherapy in patients with resectable non-small cell lung cancer: Results of the MRC LU22/NVALT 2/EORTC 08012 multicentre randomized trial and update of systemic review
    • Gilligan D, Nicolson M, Smith I, et al: Preoperative chemotherapy in patients with resectable non-small cell lung cancer: Results of the MRC LU22/NVALT 2/EORTC 08012 multicentre randomized trial and update of systemic review. Lancet 369:1929-1937, 2007
    • (2007) Lancet , vol.369 , pp. 1929-1937
    • Gilligan, D.1    Nicolson, M.2    Smith, I.3
  • 33
    • 26444567025 scopus 로고    scopus 로고
    • S9900: A phase III trial of surgery alone or surgery plus preoperative(preop) paclitaxel/carboplatin(PC) chemotherapy in early stage non-small cell lung cancer (NSCLC) preliminary results
    • suppl; abstr 7012, 624s
    • Pisters K, Vallieres E, Bunn P, et al: S9900: A phase III trial of surgery alone or surgery plus preoperative(preop) paclitaxel/carboplatin(PC) chemotherapy in early stage non-small cell lung cancer (NSCLC) preliminary results. J Clin Oncol 23:624s, 2005 (suppl; abstr 7012)
    • (2005) J Clin Oncol , vol.23
    • Pisters, K.1    Vallieres, E.2    Bunn, P.3
  • 34
    • 0012381722 scopus 로고    scopus 로고
    • Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (The IDEAL 1 Trial) [corrected]
    • Fukuoka M, Yano S, Giaccone G, et al: Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (The IDEAL 1 Trial) [corrected]. J Clin Oncol 21:2237-2246, 2003
    • (2003) J Clin Oncol , vol.21 , pp. 2237-2246
    • Fukuoka, M.1    Yano, S.2    Giaccone, G.3
  • 35
    • 24944440830 scopus 로고    scopus 로고
    • TRIBUTE: A phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small-cell lung cancer
    • Herbst RS, Prager D, Hermann R, et al: TRIBUTE: A phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small-cell lung cancer. J Clin Oncol 23:5892-5899, 2005
    • (2005) J Clin Oncol , vol.23 , pp. 5892-5899
    • Herbst, R.S.1    Prager, D.2    Hermann, R.3
  • 36
    • 22044445517 scopus 로고    scopus 로고
    • Erlotinib in previously treated non-small-cell lung cancer
    • Shepherd FA, Rodrigues Pereira J, Ciuleanu T, et al: Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med 353:123-132, 2005
    • (2005) N Engl J Med , vol.353 , pp. 123-132
    • Shepherd, F.A.1    Rodrigues Pereira, J.2    Ciuleanu, T.3
  • 37
    • 27144483349 scopus 로고    scopus 로고
    • Increases of amphiregulin and transforming growth factor-alpha in serum as predictors of poor response to gefitinib among patients with advanced non-small cell lung cancers
    • Ishikawa N, Daigo Y, Takano A, et al: Increases of amphiregulin and transforming growth factor-alpha in serum as predictors of poor response to gefitinib among patients with advanced non-small cell lung cancers. Cancer Res 65:9176-9184, 2005
    • (2005) Cancer Res , vol.65 , pp. 9176-9184
    • Ishikawa, N.1    Daigo, Y.2    Takano, A.3
  • 38
    • 33750962024 scopus 로고    scopus 로고
    • Molecular predictors of outcome with gefitinib in a phase III placebo-controlled study in advanced non-small-cell lung cancer
    • Hirsch FR, Varella-Garcia M, Bunn PA, et al: Molecular predictors of outcome with gefitinib in a phase III placebo-controlled study in advanced non-small-cell lung cancer. J Clin Oncol 24:5034-5042, 2006
    • (2006) J Clin Oncol , vol.24 , pp. 5034-5042
    • Hirsch, F.R.1    Varella-Garcia, M.2    Bunn, P.A.3
  • 39
    • 53949092103 scopus 로고    scopus 로고
    • Molecular and clinical subgroup analyses from a phase III trial comparing gefitinib with docetaxel in previously treated non-small cell lung cancer (INTEREST)
    • suppl; abstr 8001, 15s
    • Douillard J, Hirsh V, Mok TS, et al: Molecular and clinical subgroup analyses from a phase III trial comparing gefitinib with docetaxel in previously treated non-small cell lung cancer (INTEREST). J Clin Oncol 26:15s, 2008 (suppl; abstr 8001)
    • (2008) J Clin Oncol , vol.26
    • Douillard, J.1    Hirsh, V.2    Mok, T.S.3
  • 40
    • 5644296647 scopus 로고    scopus 로고
    • O-242 Gefitinib (Iressa, ZD 1839) monotherapy for pretreated advanced non-small cell lung cancer in IDEAL 1 and 2: Tumor response is not clinically relevantly predictable from tumor EGFR membrane staining alone
    • suppl, 71s
    • Bailey R, Kris M, Wolf M, et al: O-242 Gefitinib (Iressa, ZD 1839) monotherapy for pretreated advanced non-small cell lung cancer in IDEAL 1 and 2: Tumor response is not clinically relevantly predictable from tumor EGFR membrane staining alone. Lung Cancer 41:71s, 2003 (suppl)
    • (2003) Lung Cancer , vol.41
    • Bailey, R.1    Kris, M.2    Wolf, M.3
  • 41
    • 3843116718 scopus 로고    scopus 로고
    • Analysis of epidermal growth factor receptor expression as a predictive factor for response to gefitinib (Iressa, ZD 1839) in non-small cell lung cancer
    • Parra HS, Cavina R, Latteri F, et al: Analysis of epidermal growth factor receptor expression as a predictive factor for response to gefitinib (Iressa, ZD 1839) in non-small cell lung cancer. Br J Cancer 91:208-212, 2004
    • (2004) Br J Cancer , vol.91 , pp. 208-212
    • Parra, H.S.1    Cavina, R.2    Latteri, F.3
  • 42
    • 4344646459 scopus 로고    scopus 로고
    • Determinants of tumor response and survival with erlotinib in patients with non-small-cell lung cancer
    • Perez-Soler R, Chachoua A, Hammond LA, et al: Determinants of tumor response and survival with erlotinib in patients with non-small-cell lung cancer. J Clin Oncol 22:3238-3247, 2004
    • (2004) J Clin Oncol , vol.22 , pp. 3238-3247
    • Perez-Soler, R.1    Chachoua, A.2    Hammond, L.A.3
  • 43
    • 33947389287 scopus 로고    scopus 로고
    • EGFR mutation and copy number, EGFR protein expression and KRAS mutation as predictors of outcome with erlotinib in bronchioloalveolar cell carcinoma (BAC): Results of a prospective phase II trial
    • suppl; abstr 7003, 364s
    • Miller VA, Zakowski M, Riely GJ, et al: EGFR mutation and copy number, EGFR protein expression and KRAS mutation as predictors of outcome with erlotinib in bronchioloalveolar cell carcinoma (BAC): Results of a prospective phase II trial. J Clin Oncol 24:364s, 2006 (suppl; abstr 7003)
    • (2006) J Clin Oncol , vol.24
    • Miller, V.A.1    Zakowski, M.2    Riely, G.J.3
  • 44
    • 34248140107 scopus 로고    scopus 로고
    • Phase III study of erlotinib in combination with cisplatin and gemcitabine in advanced non-small-cell lung cancer: The Tarceva Lung Cancer Investigation Trial
    • Gatzemeier U, Pluzanska A, Szczesna A, et al: Phase III study of erlotinib in combination with cisplatin and gemcitabine in advanced non-small-cell lung cancer: The Tarceva Lung Cancer Investigation Trial. J Clin Oncol 25:1545-1552, 2007
    • (2007) J Clin Oncol , vol.25 , pp. 1545-1552
    • Gatzemeier, U.1    Pluzanska, A.2    Szczesna, A.3
  • 45
    • 20444502086 scopus 로고    scopus 로고
    • Assessing epidermal growth factor receptor expression in tumors: What is the value of current test methods?
    • Dei Tos AP, Ellis I: Assessing epidermal growth factor receptor expression in tumors: What is the value of current test methods? Eur J Cancer 41:1383-1392, 2005
    • (2005) Eur J Cancer , vol.41 , pp. 1383-1392
    • Dei Tos, A.P.1    Ellis, I.2
  • 46
    • 39749144726 scopus 로고    scopus 로고
    • Biomarkers of response to epidermal growth factor receptor inhibitors in Non-Small-Cell Lung Cancer Working Group: Standardization for use in the clinical trial setting
    • Eberhard DA, Giaccone G, Johnson BE: Biomarkers of response to epidermal growth factor receptor inhibitors in Non-Small-Cell Lung Cancer Working Group: Standardization for use in the clinical trial setting. J Clin Oncol 26:983-994, 2008
    • (2008) J Clin Oncol , vol.26 , pp. 983-994
    • Eberhard, D.A.1    Giaccone, G.2    Johnson, B.E.3
  • 47
    • 27244443759 scopus 로고    scopus 로고
    • Increased epidermal growth factor receptor gene copy number detected by fluorescence in situ hybridization associates with increased sensitivity to gefitinib in patients with bronchioalveolar carcinoma subtypes: A Southwest Oncology Group Study
    • Hirsch FR, Varella-Garcia M, McCoy J, et al: Increased epidermal growth factor receptor gene copy number detected by fluorescence in situ hybridization associates with increased sensitivity to gefitinib in patients with bronchioalveolar carcinoma subtypes: A Southwest Oncology Group Study. J Clin Oncol 23:6838-6845, 2005
    • (2005) J Clin Oncol , vol.23 , pp. 6838-6845
    • Hirsch, F.R.1    Varella-Garcia, M.2    McCoy, J.3
  • 48
    • 52049090365 scopus 로고    scopus 로고
    • Role of KRAS and EGFR as biomarkers of response to erlotinib in National Cancer Institute of Canada Clinical Trials Group study BR.21
    • Zhu CQ, da Cunha Santos G, Ding K, et al: Role of KRAS and EGFR as biomarkers of response to erlotinib in National Cancer Institute of Canada Clinical Trials Group study BR.21. J Clin Oncol 26:4268-4275, 2008
    • (2008) J Clin Oncol , vol.26 , pp. 4268-4275
    • Zhu, C.Q.1    da Cunha Santos, G.2    Ding, K.3
  • 49
    • 34547098367 scopus 로고    scopus 로고
    • Impact of HER2 and EGFR gene status on gefitinib-treated patients with nonsmall-cell lung cancer
    • Soh J, Toyooka S, Ichihara S, et al: Impact of HER2 and EGFR gene status on gefitinib-treated patients with nonsmall-cell lung cancer. Int J Cancer 121:1162-1167, 2007
    • (2007) Int J Cancer , vol.121 , pp. 1162-1167
    • Soh, J.1    Toyooka, S.2    Ichihara, S.3
  • 50
    • 34247628837 scopus 로고    scopus 로고
    • Comparative analysis of epidermal growth factor receptor mutations and gene amplification as predictors of gefitinib efficacy in Japanese patients with nonsmall-cell lung cancer
    • Sone T, Kasahara K, Kimura H, et al: Comparative analysis of epidermal growth factor receptor mutations and gene amplification as predictors of gefitinib efficacy in Japanese patients with nonsmall-cell lung cancer. Cancer 109:1836-1844, 2007
    • (2007) Cancer , vol.109 , pp. 1836-1844
    • Sone, T.1    Kasahara, K.2    Kimura, H.3
  • 51
    • 24944497744 scopus 로고    scopus 로고
    • Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib
    • Eberhard DA, Johnson BE, Amler LC, et al: Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib. J Clin Oncol 23:5900-5909, 2005
    • (2005) J Clin Oncol , vol.23 , pp. 5900-5909
    • Eberhard, D.A.1    Johnson, B.E.2    Amler, L.C.3
  • 52
    • 15744372810 scopus 로고    scopus 로고
    • KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib
    • Pao W, Wang TY, Riely GJ, et al: KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib. PLoS Med 2:e17, 2005
    • (2005) PLoS Med , vol.2
    • Pao, W.1    Wang, T.Y.2    Riely, G.J.3
  • 53
    • 29244463359 scopus 로고    scopus 로고
    • Mutational analysis of K-RAS and EGFR implicates K-RAS as a resistance marker in the Southwest Oncology Group (SWOG) trial S0126 of bronchioalveolar carcinoma (BAC) patients (pts) treated with gefitinib
    • suppl; abstr 7008, 623s
    • Gumerlock PH, Holland WS, Chen H, et al: Mutational analysis of K-RAS and EGFR implicates K-RAS as a resistance marker in the Southwest Oncology Group (SWOG) trial S0126 of bronchioalveolar carcinoma (BAC) patients (pts) treated with gefitinib. J Clin Oncol 23:623s, 2005 (suppl; abstr 7008)
    • (2005) J Clin Oncol , vol.23
    • Gumerlock, P.H.1    Holland, W.S.2    Chen, H.3
  • 54
    • 53949092103 scopus 로고    scopus 로고
    • Molecular and clinical subgroup analyses from a phase III trial comparing gefitinib with docetaxel in previously treated non-small cell lung cancer (INTEREST)
    • suppl; abstr 8001, 424s
    • Douillard J, Hirsh V, Mok TS, et al: Molecular and clinical subgroup analyses from a phase III trial comparing gefitinib with docetaxel in previously treated non-small cell lung cancer (INTEREST). J Clin Oncol 26:424s, 2008 (suppl; abstr 8001)
    • (2008) J Clin Oncol , vol.26
    • Douillard, J.1    Hirsh, V.2    Mok, T.S.3
  • 55
    • 36849041454 scopus 로고    scopus 로고
    • Prognostic and predictive importance of p53 and RAS for adjuvant chemotherapy in non-small-cell lung cancer
    • Tsao MS, Aviel-Romen S, Ding K, et al: Prognostic and predictive importance of p53 and RAS for adjuvant chemotherapy in non-small-cell lung cancer. J Clin Oncol 25:5240-5247, 2007
    • (2007) J Clin Oncol , vol.25 , pp. 5240-5247
    • Tsao, M.S.1    Aviel-Romen, S.2    Ding, K.3
  • 56
    • 0141570766 scopus 로고    scopus 로고
    • The sensitivity of lung cancer cell lines to the EGFR-selective tyrosine kinase inhibitor ZD1839 ('Iressa') is not related to the expression of EGFR or HER-2 or to K-ras gene status
    • Suzuki T, Nakagawa T, Endo H, et al: The sensitivity of lung cancer cell lines to the EGFR-selective tyrosine kinase inhibitor ZD1839 ('Iressa') is not related to the expression of EGFR or HER-2 or to K-ras gene status. Lung Cancer 42:35-41, 2003
    • (2003) Lung Cancer , vol.42 , pp. 35-41
    • Suzuki, T.1    Nakagawa, T.2    Endo, H.3
  • 57
    • 84871466051 scopus 로고    scopus 로고
    • Mok T, Wu YL, Thongprasert S, et al: Phase III, randomized, open-label, first line study of gefitinib vs carboplatin/paclitaxel in clinically selected patients with advanced non-small-cell lung cancer (IPASS). Ann Oncol 19:vii1, 2008 (suppl; abstr 2)
    • Mok T, Wu YL, Thongprasert S, et al: Phase III, randomized, open-label, first line study of gefitinib vs carboplatin/paclitaxel in clinically selected patients with advanced non-small-cell lung cancer (IPASS). Ann Oncol 19:vii1, 2008 (suppl; abstr 2)
  • 58
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
    • Lynch TJ, Bell DW, Sordella R, et al: Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 350:2129-2139, 2004
    • (2004) N Engl J Med , vol.350 , pp. 2129-2139
    • Lynch, T.J.1    Bell, D.W.2    Sordella, R.3
  • 59
    • 2342624080 scopus 로고    scopus 로고
    • EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
    • Paez JG, Janne PA, Lee JC, et al: EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy. Science 304:1497-1500, 2004
    • (2004) Science , vol.304 , pp. 1497-1500
    • Paez, J.G.1    Janne, P.A.2    Lee, J.C.3
  • 60
    • 4444344330 scopus 로고    scopus 로고
    • EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
    • Pao W, Miller V, Zakowski M, et al: EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci U S A 101:13306-13311, 2004
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 13306-13311
    • Pao, W.1    Miller, V.2    Zakowski, M.3
  • 61
    • 33746034167 scopus 로고    scopus 로고
    • Exon 19 deletion mutations of epidermal growth factor receptor are associated with prolonged survival in non-small cell lung cancer patients treated with gefitinib or erlotinib
    • Jackman DM, Yeap BY, Sequist LV, et al: Exon 19 deletion mutations of epidermal growth factor receptor are associated with prolonged survival in non-small cell lung cancer patients treated with gefitinib or erlotinib. Clin Cancer Res 12:3908-3914, 2006
    • (2006) Clin Cancer Res , vol.12 , pp. 3908-3914
    • Jackman, D.M.1    Yeap, B.Y.2    Sequist, L.V.3
  • 62
    • 32944481596 scopus 로고    scopus 로고
    • Clinical course of patients with non-small cell lung cancer and epidermal growth factor receptor exon 19 and exon 21 mutations treated with gefitinib or erlotinib
    • Riely GJ, Pao W, Pham D, et al: Clinical course of patients with non-small cell lung cancer and epidermal growth factor receptor exon 19 and exon 21 mutations treated with gefitinib or erlotinib. Clin Cancer Res 12:839-844, 2006
    • (2006) Clin Cancer Res , vol.12 , pp. 839-844
    • Riely, G.J.1    Pao, W.2    Pham, D.3
  • 63
    • 20044364940 scopus 로고    scopus 로고
    • Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers
    • Shigematsu H, Lin L, Takahashi T, et al. Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. J Natl Cancer Inst 97:339-346, 2005
    • (2005) J Natl Cancer Inst , vol.97 , pp. 339-346
    • Shigematsu, H.1    Lin, L.2    Takahashi, T.3
  • 64
    • 33846444010 scopus 로고    scopus 로고
    • Response to treatment and survival of patients with non-small cell lung cancer undergoing somatic EGFR mutation testing
    • Sequist LV, Joshi VA, Janne PA, et al: Response to treatment and survival of patients with non-small cell lung cancer undergoing somatic EGFR mutation testing. Oncologist 12:90-98, 2007
    • (2007) Oncologist , vol.12 , pp. 90-98
    • Sequist, L.V.1    Joshi, V.A.2    Janne, P.A.3
  • 65
    • 28844449401 scopus 로고    scopus 로고
    • Epidermal growth factor receptor mutations and gene amplification in non-small-cell lung cancer: Molecular analysis of the IDEAL/INTACT gefitinib trials
    • Bell DW, Lynch TJ, Haserlat SM, et al: Epidermal growth factor receptor mutations and gene amplification in non-small-cell lung cancer: Molecular analysis of the IDEAL/INTACT gefitinib trials. J Clin Oncol 23:8081-8092, 2005
    • (2005) J Clin Oncol , vol.23 , pp. 8081-8092
    • Bell, D.W.1    Lynch, T.J.2    Haserlat, S.M.3
  • 66
    • 27944499351 scopus 로고    scopus 로고
    • EGFR and erbB2 mutations status in Japanese lung cancer patients
    • Sasaki H, Shimizu S, Endo K, et al: EGFR and erbB2 mutations status in Japanese lung cancer patients. Int J Cancer 118:180-184, 2006
    • (2006) Int J Cancer , vol.118 , pp. 180-184
    • Sasaki, H.1    Shimizu, S.2    Endo, K.3
  • 67
    • 57149089886 scopus 로고    scopus 로고
    • EGFR mutations predict survival benefit from gefitinib in patients with advanced lung adenocarcinoma: A historical comparison of patients treated before and after gefitinib approval in Japan
    • Takano T, Fukui T, Ohe Y, et al: EGFR mutations predict survival benefit from gefitinib in patients with advanced lung adenocarcinoma: A historical comparison of patients treated before and after gefitinib approval in Japan. J Clin Oncol 26:5589-5595, 2008
    • (2008) J Clin Oncol , vol.26 , pp. 5589-5595
    • Takano, T.1    Fukui, T.2    Ohe, Y.3
  • 68
    • 33644982287 scopus 로고    scopus 로고
    • Unraveling the mystery of prognostic and predictive factors in epidermal growth factor receptor therapy
    • Shepherd FA, Tsao MS: Unraveling the mystery of prognostic and predictive factors in epidermal growth factor receptor therapy. J Clin Oncol 24:1219-1220, 2006
    • (2006) J Clin Oncol , vol.24 , pp. 1219-1220
    • Shepherd, F.A.1    Tsao, M.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.