Dabigatran versus warfarin in patients with atrial fibrillation [1]

New England Journal of Medicine

Volumn 361, Issue 27, 2009, Pages 2671-2675

  Houston, Donald Stuart ^a   Zarychanski, Ryan ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DABIGATRAN; WARFARIN; ACETYLSALICYLIC ACID; ANTICOAGULANT AGENT; ANTITHROMBOCYTIC AGENT; BENZIMIDAZOLE DERIVATIVE; DABIGATRAN ETEXILATE; PYRIDINE DERIVATIVE; ENOXAPARIN; XIMELAGATRAN;

BODY WEIGHT; DRUG ACTIVITY; DRUG BINDING; DRUG EFFICACY; HEART ATRIUM FIBRILLATION; HUMAN; KIDNEY DYSFUNCTION; LETTER; PRIORITY JOURNAL; RISK ASSESSMENT; DRUG COMBINATION; DRUG EFFECT; HEART INFARCTION; NOTE; THROMBOCYTE ACTIVATION; CORONARY ARTERY THROMBOSIS; DEEP VEIN THROMBOSIS; LONG TERM CARE; THROMBOEMBOLISM; TREATMENT OUTCOME;

ANTICOAGULANTS; ASPIRIN; ATRIAL FIBRILLATION; BENZIMIDAZOLES; DRUG THERAPY, COMBINATION; HUMANS; MYOCARDIAL INFARCTION; PLATELET ACTIVATION; PLATELET AGGREGATION INHIBITORS; PYRIDINES; WARFARIN;

EID: 74949112784     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMc0909962     Document Type: Letter

References (5)

1. Connolly SJ, Ezekowitz MD, Yusuf S, et al. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med 2009;361:113951.
2. Fihn SD, McDonell M, Martin D, et al. Risk factors for complications of chronic anticoagulation: a multicenter study. Ann Intern Med 1993;118:51120.
3. Casais P, Luceros AS, Meschengieser S, Bermejo E, Lazzari MA. INR variability in anticoagulation with acenocoumarol: is it useful for identifying patients at risk of bleeding and thrombosis? Haematologica 1999;84:7534.
4. Connolly SJ, Pogue J, Eikelboom J, et al. Benefit of oral anti-coagulant over antiplatelet therapy in atrial fibrillation depends on the quality of international normalized ratio control achieved by centers and countries as measured by time in therapeutic range. Circulation 2008;118:202937.
5. Butchart EG, Payne N, Li HH, Buchan K, Mandana K, Grunkemeier GL. Better anticoagulation control improves survival after valve replacement. J Thorac Cardiovasc Surg 2002;123:71523.