Expression of the μ-opioid receptor on Malassezia pachydermatis and its effect in modulating phospholipase production

Medical Mycology

Volumn 48, Issue 1, 2010, Pages 73-78

  Cafarchia, C ^a   Dell'Aquila, M E ^a   Traversa, D ^b   Albrizio, M ^a   Guaricci, A C ^a   De Santis, T ^a   Otranto, D ^a  

^a UNIVERSITY OF BARI   (Italy)

^b University of Teram   (Italy)

Author keywords

opioid receptor; Malassezia pachydermatis; Naloxone; Pathogenesis; Phospholipase

Indexed keywords

MU OPIATE RECEPTOR; PHOSPHOLIPASE; FUNGAL PROTEIN; NALOXONE;

ARTICLE; CONTROLLED STUDY; DOG; ENZYME ACTIVITY; FUNGUS ISOLATION; IMMUNOFLUORESCENCE; MALASSEZIA PACHYDERMATIS; NONHUMAN; PROTEIN EXPRESSION; SKIN DEFECT; WESTERN BLOTTING; ANIMAL; ANIMAL DISEASE; BIOSYNTHESIS; CHEMISTRY; DERMATOMYCOSIS; DOG DISEASE; ENZYMOLOGY; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; ISOLATION AND PURIFICATION; MALASSEZIA; METABOLISM; MICROBIOLOGY; MOLECULAR WEIGHT; PHYSIOLOGY;

ANIMALIA; CANIS FAMILIARIS; MALASSEZIA; MALASSEZIA PACHYDERMATIS;

ANIMALS; BLOTTING, WESTERN; DERMATOMYCOSES; DOG DISEASES; DOGS; FLUORESCENT ANTIBODY TECHNIQUE; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; MALASSEZIA; MOLECULAR WEIGHT; NALOXONE; PHOSPHOLIPASES; RECEPTORS, OPIOID, MU;

EID: 74949107531     PISSN: 13693786     EISSN: 14602709     Source Type: Journal    
DOI: 10.3109/13693780902718347     Document Type: Article

References (28)

1. Chen TA, Hill PB. The biology of Malassezia organisms and their ability to induce immune responses and skin disease. Vet Dermatol 2005; 16: 4-26.
2. Bond R, Lloyd DH. Skin and mucosal populations of M alassezia pachydermatis in healthy and seborrhoeic basset hound. Vet Dermatol 1997; 8: 101-106.
3. Cafarchia C, Gallo S, Romito D, et al. Frequency, body distribution and population size of Malassezia yeasts in healthy dogs and in dogs with localized cutaneous lesions. J Vet Diagn Invest 2005; 17: 316-322
4. Cafarchia C, Otranto D. Association between phospholipase production by Malassezia pachydermatis and skin lesions. J Clin Microbiol 2004; 42: 4868-4869.
5. Corbett A, McKnight S, Anderson G. Opioid Receptors. Tocris Cookson Pharmacological review. Available from: www.tocris.com.
6. Pan YX. Diversity and complexity of the mu opioid receptor gene: alternative pre-mRNA splicing and promoters. DNA Cell Biol 2005; 24: 736-750.
7. Way WL, Fields HL, Leong WE. Analgesici oppioidi e loro antagonisti. In: Katzung BG (ed.). Farmacologia Generale e Clinica 6th edn. Padova: Piccin Nuova Libreria, 2000; 527-546.
8. Slominski A. Beta-endorphin/mu-opiate receptor system in the skin. J Invest Dermatol 2003; 120: 1073-1080.
9. Slominski A. Neuroendocrine system of the skin. Dermatology 2005; 211: 199-208.
10. Bigliardi PL, Bigliardi-Qi M, Buechner S, Rufli T. Expression of mu-opiate receptor in human epidermis and keratinocytes. J Invest Dermatol 1998; 111: 297-301.
11. Bigliardi-Qi M, Lipp B, Sumanovski LT, Buechner SA, Bigliardi PL. Changes of epidermal mu-opiate receptor expression and nerve endings in chronic atopic dermatitis. Dermatology 2005; 210: 91-99.
12. Bigliardi-Qi M, Sumanovski LT, Buchner S, Rufli T, Bigliardi PL. Mu-opiate receptor and Beta-endorphin expression in nerve endings and keratinocytes in human skin. Dermatology 2004; 209: 183-189.
13. Bigliardi-Qi M, Bigliardi PL, Eberle AN, Buchner S, Rufli T. Betaendorphin stimulates cytokeratin 16 expression and downregulates mu-opiate receptor expression in human epidermis. J Invest Dermatol 2000; 114: 527-532.
14. Georgala S, Schulpis KH, Papaconstantinou ED, Stratigos J. Raised beta-endorphin serum levels in children with atopic dermatitis and pruritus. J Dermatol Sci 1994; 8: 125-128.
15. Glinski W, Brodecka H, Glinska-Ferenz M, Kowalski D. Increased concentration of beta-endorphin in sera of patients with psoriasis and other inflammatory dermatoses. Br J Dermatol 1994; 131: 260-264.
16. Glinski W, Brodecka H, Glinska-Ferenz M, Kowalski D. Neuropeptides in psoriasis: possible role of beta-endorphin in the pathomechanism of the disease. Int J Dermatol 1994; 33: 356-360.
17. Cafarchia C, Dell'Aquila ME, Capelli G, Minoia P, Otranto D. Role of beta-endorphin on phospholipase production in Malassezia pachydermatis in dogs: new insights into the pathogenesis of this yeast. Med Mycol 2007; 45: 11-15.
18. Albrizio MA, Guaricci C, Maritato F, et al. Expression and subcellular localization of the mu-opioid receptor in equine spermatozoa: evidence for its functional role. Reproduction 2005; 129: 39-49.
19. Albrizio M, Guaricci AC, Calamita G, Zarrilli A, Minoia P. Expression and immunolocalization of the mu-opioid receptor in human sperm cells. Fertil Steril 2006; 86: 1776-1779.
20. Dell'Aquila ME, Albrizio M, Guaricci AC, et al. Expression and localization of the mu-opioid receptor (MOR) in the equine cumulusoocyte complex and its involvement in the seasonal regulation of oocyte meiotic competence. Mol Reprod Dev 2008; 75: 1229-1246.
21. Dell'Aquila ME, Casavola V., Reshkin SJ, et al. Effects of betaendorphin and Naloxone on in vitro maturation of bovine oocytes. Mol Reprod Dev 2002; 63: 210-222.
22. Reisine T, Pasternak G. Opioid analgesics and antagonists Goodman & Gilman's The Pharmacological Basis of Therapeutics 9th edn Hardman JG, Limbird LE, McGraw-Hill New York 1996; 521-555.
23. Feigenbaum JJ, Howard SG. Effects of naloxone on amphetamine induced striatal dopamine release in vivo : a microdialysis study. Life Sci 1997; 60: 1659-1668.
24. Spivak CE, Beglan CL, Seidleck BK, et al. Naloxone activation of mu-opioid receptors mutated at a histidine residue lining the opioid binding cavity. Mol Pharmacol 1997; 52: 983-992.
25. Brandon ARL, O'Dowd BF, George SR. Oligomerization of opioid receptors: generation of novel signaling units. Curr Opin Pharmacol 2002; 2: 76-81.
26. Cvejic S, Devi LA. Dimerization of the delta opioid receptor: implication for a role in receptor internalization. J Biol Chem 1997; 272: 26959-26964.
27. Xue C, Hsueh YP, Heitman J. Magnifi cent seven: roles of G proteincoupled receptors in extracellular sensing in fungi. FEMS Microbiol Rev 2008; 32: 1010-1032.
28. Witkin SS, Kalo-Klein A. Enhancement of germ tube formation in Candida albicans by beta-endorphin. Am J Obstet Gynecol 1991; 164: 917-920.