Protein domain boundary prediction from residue sequence alone using Bayesian Neural Networks

Proceedings of the 2nd WSEAS International Conference on Biomedical Electronics and Biomedical Informatics, BEBI '09

Volumn , Issue , 2009, Pages 209-213

  Sanchez, David ^a   Courellis, Spiros H ^a  

^a CALIFORNIA STATE UNIVERSITY   (United States)

Author keywords

Bayesian; Boundaries; Domain; Feed; Forward; MLP; Networks; Neural; Protein

Indexed keywords

ARTIFICIAL NEURAL NETWORK; BAYESIAN; BAYESIAN METHODS; BAYESIAN NEURAL NETWORKS; BOUNDARIES; DOMAIN BOUNDARY; FEED FORWARD; FEED-FORWARD ARTIFICIAL NEURAL NETWORKS; PROTEIN DOMAINS; PROTEIN RESIDUES; SOFTWARE TOOL; TRAINING AND TESTING;

BAYESIAN NETWORKS; BINARY SEQUENCES; BIOINFORMATICS; EMBEDDED SOFTWARE; PROTEINS;

NEURAL NETWORKS;

EID: 74949106231     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (8)

1. S. Salzberg, D. Searls, and S. Kasif, Eds. Computational Methods in Molecular Biology, vol. 32 of New Comprehensive Biochemistry. Amsterdam: Elsevier Science B.V., 1998.
2. A. L. Cuff, I. Sillitoe, T. Lewis, O. C. Redfern, R. Garratt, J. Thornton, and C. A. Orengo, "The cath classification revisited- architectures reviewed and new ways to characterize structural divergence in superfamilies," Nucl. Acids Res., No. 37, 2009, pp. 310-314.
3. A. G. Murzin, S. E. Brenner, T. Hubbard, and C. Chothia, "SCOP: a structural classification of proteins database for the investigation of sequences and structures," J. Mol. Biol., No. 247 1995, pp. 536-540.
4. J. Sim and S. Y. Kim, J. Lee, "PPRODO: Prediction of protein domain boundaries using neural networks," Proteins: Structure, Function, and Bioinformatics, No. 59, 2005, pp. 627-632.
5. L. Ye, T. Liu, Z. Wu, and R. Zhou, "Sequence-based protein domain boundary prediction using bp neural network with various property profiles," Proteins: Structure, Function, and Bioinformatics, No. 71, 2008, pp. 300-307.
6. Q. Ma, and J. T. L. Wang, "Biological Data Mining Using Bayesian Neural Networks: A Case Study," International Journal on Artificial Intelligence Tools, vol. 8, No. 4, 1999, pp. 433-451.
7. P. E. Bourne, and H. Weissig, Structural Bioinformatics, Hoboken, New Jersey: Wiley-Liss, Inc., 2003.
8. D. J. C. MacKay, "Probable Networks and Plausible Predictions - A Review of Practical Bayesian Methods for Supervised Neural Networks," Network: Computation in Neural Systems, No. 6, 1993, pp. 469-505.