Genetic factors underlie stability of obsessive-compulsive symptoms

Twin Research and Human Genetics

Volumn 12, Issue 5, 2009, Pages 411-419

  Van Grootheest, Daniël S ^a   Cath, Daniëlle ^b   Hottenga, Jouke Jan ^a   Beekman, Aartjan T ^a   Boomsma, Dorret I ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Longitudinal; Obsessive compulsive disorder; OC symptoms; OCD; Twin study; Twins

Indexed keywords

ARTICLE; FEMALE; GENETIC ANALYSIS; GENETIC STABILITY; HEREDITY; HERITABILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; OBSESSIVE COMPULSIVE DISORDER; PRIORITY JOURNAL; SEX DIFFERENCE; SYMPTOM; TWINS; ADULT; DIZYGOTIC TWINS; GENETIC PREDISPOSITION; GENETICS; MONOZYGOTIC TWINS;

ADULT; DISEASES IN TWINS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; OBSESSIVE-COMPULSIVE DISORDER; TWINS, DIZYGOTIC; TWINS, MONOZYGOTIC;

EID: 74949100543     PISSN: 18324274     EISSN: None     Source Type: Journal    
DOI: 10.1375/twin.12.5.411     Document Type: Article

References (39)

1. Achenbach, T. M. (1997). Manual for the Young Adult Self Report and Young Adult Behavior Checklist. Burlington, VT: University of Vermont, Department of Psychiatry.
2. Alonso, P., Menchon, J. M., Pifarre, J., Mataix-Cols, D., Torres, L., Salgado, P., & Vallejo, J. (2001). Long-term follow-up and predictors of clinical outcome in obsessive-compulsive patients treated with serotonin reuptake inhibitors and behavioral therapy. Journal of Clinical Psychiatry, 62, 535-540.
3. Angst, J., Gamma, A., Endrass, J., Goodwin, R., Ajdacic, V., Eich, D., & Rossler, W. (2004). Obsessive-compulsive severity spectrum in the community: Prevalence, comorbidity, and course. European Archives of Psychiatry and Clinical Neuroscience, 254, 156-164.
4. Boomsma, D., Busjahn, A., & Peltonen, L. (2002a). Classical twin studies and beyond. Nature Reviews Genetics, 3, 872-882.
5. Boomsma, D. I., de Geus, E. J., Vink, J. M., Stubbe, J. H., Distel, M. A., Hottenga, J. J., Posthuma, D., van Beijsterveldt, C. E., Hudziak, J. J., Bartels, M., & Willemsen, G. (2006). Netherlands Twin Register: From twins to twin families. Twin Research and Human Genetics, 9, 849-857.
6. Boomsma, D. I. & Molenaar, P. C. (1987). The genetic analysis of repeated measures. I. Simplex models. Behavior Genetics, 17, 111-123.
7. Boomsma, D. I., Vink, J. M., van Beijsterveldt, T. C., de Geus, E. J., Beem, A. L., Mulder, E. J., Derks, E. M., Riese, H., Willemsen, G. A., Bartels, M., van den, B. M., Kupper, N. H., Polderman, T. J., Posthuma, D., Rietveld, M. J., Stubbe, J. H., Knol, L. I., Stroet, T., & Van Baal, G. C. (2002b). Netherlands Twin Register: a focus on longitudinal research. Twin Research, 5, 401-406.
8. Cath, D. C., van Grootheest, D. S., Willemsen, G., Van Oppen, P., & Boomsma, D. I. (2008). Environmental factors in obsessive-compulsive behavior: Evidence from discordant and concordant monozygotic twins. Behavior Genetics, 38, 108-120.
9. Cornes, B. K., Zhu, G., & Martin, N. G. (2007). Sex differences in genetic variation in weight: A longitudinal study of body mass index in adolescent twins. Behavior Genetics, 37, 648-660.
10. Crino, R., Slade, T., & Andrews, G. (2005). The changing prevalence and severity of obsessive-compulsive disorder criteria from DSM-III to DSM-IV. American Journal of Psychiatry, 162, 876-882.
11. Derks, E. M., Dolan, C. V., & Boomsma, D. I. (2004). Effects of censoring on parameter estimates and power in genetic modeling. Twin Research, 7, 659-669.
12. Eisen, J. L., Goodman, W. K., Keller, M. B., Warshaw, M. G., DeMarco, L. M., Luce, D. D., & Rasmussen, S. A. (1999). Patterns of remission and relapse in obsessivecompulsive disorder: A 2-year prospective study. Journal of Clinical Psychiatry, 60, 346-351.
13. Foa, E. B., Huppert, J. D., Leiberg, S., Langner, R., Kichic, R., Hajcak, G., & Salkovskis, P. M. (2002). The obsessive-compulsive Inventory: Development and validation of a short version. Psychological Assessment, 14, 485-496.
14. Fullana, M. A., Tortella-Feliu, M., Caseras, X., Taberner, J., Torrubia, R., & Mataix-Cols, D. (2007). Temporal stability of obsessive-compulsive symptom dimensions in an undergraduate sample: A prospective 2-year follow-up study. Behavior Modification, 31, 815-824.
15. Geller, D. A., Doyle, R., Shaw, D., Mullin, B., Coffey, B. J., Petty C, Vivas, F., & Biederman, J. (2006). A quick and reliable screening measure for OCD in Youth: Reliability and validity of the Obsessive Compulsive Scale of the Child Behavior Checklist. Comprehensive Psychiatry, 47, 234-240.
16. Goodwin, D. W., Guze, S. B., & Robins, E. (1969). Follow-up studies in obsessional neurosis. Archives of General Psychiatry, 20, 182-187.
17. Hudziak, J. J., Althoff, R. R., Stanger, C., van Beijsterveldt, C. E., Nelson, E. C., Hanna, G. L., Boomsma, D. I., & Todd, R. D. (2006). The Obsessive Compulsive Scale of the Child Behavior Checklist predicts obsessive-compulsive disorder: A receiver operating characteristic curve analysis. Journal of Child Psychology and Psychiatry, 47, 160-166.
18. Jonnal, A. H., Gardner, C. O., Prescott, C. A., & Kendler, K. S. (2000). Obsessive and compulsive symptoms in a general population sample of female twins. American Journal of Medical Genetics, 96, 791-796.
19. Kendler, K. S. (2005). Psychiatric genetics: A methodologic critique. American Journal of Psychiatry, 162, 3-11.
20. Neale, M. C., Boker, S. M., Xie, G., & Maes, H. M. (2006). Mx: Statistical modeling (7th ed.) Richmond, VA: Virginia Commonwealth University.
21. Neale, M. C. & Cardon, L. R. (1992). Methodology for genetic studies of twins and families. Dordrecht, The Netherlands: Kluwer Academic Publishers.
22. Nelson, E. C., Hanna, G. L., Hudziak, J. J., Botteron, K. N., Heath, A. C., & Todd, R. D. (2001). Obsessive-compulsive scale of the child behavior checklist: Specificity, sensitivity, and predictive power. Pediatrics, 108, E14.
23. Nestadt, G., Bienvenu, O. J., Cai, G., Samuels, J., & Eaton, W. W. (1998). Incidence of obsessive-compulsive disorder in adults. Journal of Nervous and Mental Disease, 186, 401-406.
24. Oppen van, P. (1992). Obsessions and compulsions: dimensional structure, reliability, convergent and divergent validity of the Padua Inventory. Behavior Research and Therapy, 30, 631-637.
25. Oppen van, P., Hoekstra R. J., & Emmelkamp, P. M. G. (1995). The structure of obsessive-compulsive symptoms. Behavior Research and Therapy, 33, 15-23.
26. Orloff, L. M., Battle, M. A., Baer, L., Ivanjack, L., Pettit, A. R., Buttolph, M. L., & Jenike, M. A. (1994). Long-term follow-up of 85 patients with obsessive-compulsive disorder. American Journal of Psychiatry, 151, 441-442.
27. Rasmussen, S. A. & Tsuang, M. T. (1986). Clinical characteristics and family history in DSM-III obsessive-compulsive disorder. American Journal of Psychiatry, 143, 317-322.
28. Reddy, Y. C., D'Souza, S. M., Shetti, C., Kandavel, T., Deshpande, S., Badamath, S., & Singisetti, S. (2005). An 11- to 13-year follow-up of 75 subjects with obsessive-compulsive disorder. Journal of Clinical Psychiatry, 66, 744-749.
29. Sanavio, E. (1988). Obsessions and compulsions: The Padua Inventory. Behavior Research and Therapy, 26, 169-177.
30. Skoog, G. & Skoog, I. (1999). A 40-year follow-up of patients with obsessive-compulsive disorder. Archives of General Psychiatry, 56, 121-127.
31. Steketee, G., Eisen, J., Dyck, I., Warshaw, M., & Rasmussen, S. (1999). Predictors of course in obsessive-compulsive disorder. Psychiatry Research, 89, 229-238.
32. Stewart, S. E., Geller, D. A., Jenike, M., Pauls, D., Shaw, D., Mullin, B., & Faraone, S. V. (2004). Long-term outcome of pediatric obsessive-compulsive disorder: A meta-analysis and qualitative review of the literature. Acta Psychiatrica Scandinavica, 110, 4-13.
33. Torres, A. R., Prince, M. J., Bebbington, P. E., Bhugra, D., Brugha, T. S., Farrell, M., Jenkins, R., Lewis, G., Meltzer, H., & Singleton, N. (2006). Obsessive-compulsive disorder: Prevalence, comorbidity, impact, and help-seeking in the British national psychiatric morbidity survey of 2000. American Journal of Psychiatry, 163, 1978-1985.
34. van Beijsterveldt, C. E., Bartels, M., Hudziak, J. J., & Boomsma, D. I. (2003). Causes of stability of aggression from early childhood to adolescence: A longitudinal genetic analysis in Dutch twins. Behavior Genetics, 33, 591-605.
35. van den Oord, E. J., Pickles, A., & Waldman, I. D. (2003). Normal variation and abnormality: An empirical study of the liability distributions underlying depression and delinquency. Journal of Child Psychology and Psychiatry, 44, 180-192.
36. van Grootheest, D. S., Bartels, M., Cath, D. C., Beekman, A. T., Hudziak, J. J., & Boomsma, D. I. (2007a). Genetic and environmental contributions underlying stability in childhood obsessive-compulsive behavior. Biological Psychiatry, 61, 308-315.
37. van Grootheest, D. S., Cath, D. C., Beekman, A. T., & Boomsma, D. I. (2007b). Genetic and environmental influences on obsessive-compulsive symptoms in adults: A population-based twin-family study. Psychological Medicine, 37, 1635-1644.
38. van Grootheest, D. S., van den Berg, S. M., Cath, D. C., Willemsen, G., & Boomsma, D. I. (2008). Marital resemblance for obsessive-compulsive, anxious and depressive symptoms in a population-based sample. Psychological Medicine, 38, 1731-1740.
39. Willemsen, G., Posthuma, D., & Boomsma, D. I. (2005). Environmental factors determine where the Dutch live: results from the Netherlands twin register. Twin Research and Human Genetics, 8, 312-317.