메뉴 건너뛰기




Volumn 40, Issue 1, 2009, Pages 10-16

A phase II study of irinotecan and capecitabine for patients with unresectable liver-only metastases from colorectal cancer

Author keywords

Capecitabine; Colorectal cancer; Irinotecan; Liver metastases

Indexed keywords

CAPECITABINE; DEXAMETHASONE; IRINOTECAN; LOPERAMIDE; SEROTONIN ANTAGONIST; ANTINEOPLASTIC AGENT; CAMPTOTHECIN; DEOXYCYTIDINE; DRUG DERIVATIVE; FLUOROURACIL;

EID: 74949095614     PISSN: 03682811     EISSN: 14653621     Source Type: Journal    
DOI: 10.1093/jjco/hyp114     Document Type: Article
Times cited : (8)

References (35)
  • 2
    • 0022969737 scopus 로고
    • Haematogenous metastatic patterns in colonic carcinoma: an analysis of 1541 necropsies
    • Weiss L, Grundmann E, Torhorst J, Hartveit F, Moberg I, Eder M, et al. Haematogenous metastatic patterns in colonic carcinoma: an analysis of 1541 necropsies. J Pathol 1986;150:195-203.
    • (1986) J Pathol , vol.150 , pp. 195-203
    • Weiss, L.1    Grundmann, E.2    Torhorst, J.3    Hartveit, F.4    Moberg, I.5    Eder, M.6
  • 3
    • 43749090901 scopus 로고    scopus 로고
    • Tritherapy with fluorouracil/leucovorin, irinotecan and oxaliplatin (FOLFIRINOX): a phase II study in colorectal cancer patients with non-resectable liver metastases
    • Ychou M, Viret F, Kramar A, Desseigne F, Mitry E, Guimbaud R, et al. Tritherapy with fluorouracil/leucovorin, irinotecan and oxaliplatin (FOLFIRINOX): a phase II study in colorectal cancer patients with non-resectable liver metastases. Cancer Chemother Pharmacol 2008;62:195-201.
    • (2008) Cancer Chemother Pharmacol , vol.62 , pp. 195-201
    • Ychou, M.1    Viret, F.2    Kramar, A.3    Desseigne, F.4    Mitry, E.5    Guimbaud, R.6
  • 4
    • 15744374738 scopus 로고    scopus 로고
    • Neoadjuvant chemotherapy before liver resection for patients with unresectable liver metastases from colorectal carcinoma
    • Leonard GD, Brenner B, Kemeny NE. Neoadjuvant chemotherapy before liver resection for patients with unresectable liver metastases from colorectal carcinoma. J Clin Oncol 2005;23:2038-48.
    • (2005) J Clin Oncol , vol.23 , pp. 2038-2048
    • Leonard, G.D.1    Brenner, B.2    Kemeny, N.E.3
  • 5
    • 0034712536 scopus 로고    scopus 로고
    • Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial
    • Douillard JY, Cunningham D, Roth AD, Navarro M, James RD, Karasek P, et al. Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial. Lancet 2000;355:1041-7.
    • (2000) Lancet , vol.355 , pp. 1041-1047
    • Douillard, J.Y.1    Cunningham, D.2    Roth, A.D.3    Navarro, M.4    James, R.D.5    Karasek, P.6
  • 6
    • 0033874892 scopus 로고    scopus 로고
    • Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer
    • de Gramont A, Figer A, Seymour M, Homerin M, Hmissi A, Cassidy J, et al. Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer. J Clin Oncol 2000;18:2938-47.
    • (2000) J Clin Oncol , vol.18 , pp. 2938-2947
    • de Gramont, A.1    Figer, A.2    Seymour, M.3    Homerin, M.4    Hmissi, A.5    Cassidy, J.6
  • 7
    • 1342290189 scopus 로고    scopus 로고
    • FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study
    • Tournigand C, André T, Achille E, Lledo G, Flesh M, Mery-Mignard D, et al. FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study. J Clin Oncol 2004;22:229-37.
    • (2004) J Clin Oncol , vol.22 , pp. 229-237
    • Tournigand, C.1    André, T.2    Achille, E.3    Lledo, G.4    Flesh, M.5    Mery-Mignard, D.6
  • 8
    • 23844448040 scopus 로고    scopus 로고
    • Neoadjuvant treatment of unresectable colorectal liver metastases: correlation between tumour response and resection rates
    • Folprecht G, Grothey A, Alberts S, Raab HR, Köhne CH. Neoadjuvant treatment of unresectable colorectal liver metastases: correlation between tumour response and resection rates. Ann Oncol 2005;16:1311-9.
    • (2005) Ann Oncol , vol.16 , pp. 1311-1319
    • Folprecht, G.1    Grothey, A.2    Alberts, S.3    Raab, H.R.4    Köhne, C.H.5
  • 9
    • 0034745284 scopus 로고    scopus 로고
    • Capecitabine (Xeloda) improves medical resource use compared with 5-fluorouracil plus leucovorin in a phase III trial conducted in patients with advanced colorectal carcinoma
    • Twelves C, Boyer M, Findlay M, Cassidy J, Weitzel C, Barker C, et al. Capecitabine (Xeloda) improves medical resource use compared with 5-fluorouracil plus leucovorin in a phase III trial conducted in patients with advanced colorectal carcinoma. Eur J Cancer 2001;37:597-604.
    • (2001) Eur J Cancer , vol.37 , pp. 597-604
    • Twelves, C.1    Boyer, M.2    Findlay, M.3    Cassidy, J.4    Weitzel, C.5    Barker, C.6
  • 10
    • 0024420685 scopus 로고
    • Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin
    • Hsiang YH, Lihou MG, Liu LF. Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin. Cancer Res 1989;49:5077-82.
    • (1989) Cancer Res , vol.49 , pp. 5077-5082
    • Hsiang, Y.H.1    Lihou, M.G.2    Liu, L.F.3
  • 11
    • 0028225471 scopus 로고
    • Comparison of topoisomerase I inhibition, DNA damage, and cytotoxicity of camptothecin derivatives presently in clinical trials
    • Tanizawa A, Fujimori A, Fujimori Y, Pommier Y. Comparison of topoisomerase I inhibition, DNA damage, and cytotoxicity of camptothecin derivatives presently in clinical trials. J Natl Cancer Inst 1994;86:836-42.
    • (1994) J Natl Cancer Inst , vol.86 , pp. 836-842
    • Tanizawa, A.1    Fujimori, A.2    Fujimori, Y.3    Pommier, Y.4
  • 12
    • 0003292907 scopus 로고    scopus 로고
    • Enhanced antitumor activity of xeloda by irinotecan in nude mice bearing human A253 and FaDu head neck xenografts
    • Cao S, Hapke G, Rustum YM. Enhanced antitumor activity of xeloda by irinotecan in nude mice bearing human A253 and FaDu head and neck xenografts. Proc Am Assoc Cancer Res 2001;42:464.
    • (2001) Proc Am Assoc Cancer Res , vol.42 , pp. 464
    • Cao, S.1    Hapke, G.2    Rustum, Y.M.3
  • 13
    • 0141613762 scopus 로고    scopus 로고
    • Capecitabine and irinotecan as first-line chemotherapy in patients with metastatic colorectal cancer: results of an extended phase I study
    • Tewes M, Schleucher N, Achterrath W, Wilke HJ, Frings S, Seeber S, et al. Capecitabine and irinotecan as first-line chemotherapy in patients with metastatic colorectal cancer: results of an extended phase I study. Ann Oncol 2003;14:1442-8.
    • (2003) Ann Oncol , vol.14 , pp. 1442-1448
    • Tewes, M.1    Schleucher, N.2    Achterrath, W.3    Wilke, H.J.4    Frings, S.5    Seeber, S.6
  • 14
    • 9144255466 scopus 로고    scopus 로고
    • Randomized multicenter Phase II trial of two different schedules of irinotecan combined with capecitabine as first-line treatment in metastatic colorectal carcinoma
    • Bajetta E, Di Bartolomeo M, Mariani L, Cassata A, Artale S, Frustaci S, et al. Randomized multicenter Phase II trial of two different schedules of irinotecan combined with capecitabine as first-line treatment in metastatic colorectal carcinoma. Cancer 2004;100:279-87.
    • (2004) Cancer , vol.100 , pp. 279-287
    • Bajetta, E.1    Di Bartolomeo, M.2    Mariani, L.3    Cassata, A.4    Artale, S.5    Frustaci, S.6
  • 15
    • 0033050165 scopus 로고    scopus 로고
    • Multicenter phase II study of capecitabine in paclitaxel-refractory metastatic breast cancer
    • Blum JL, Jones SE, Buzdar AU, LoRusso PM, Kuter I, Vogel C, et al. Multicenter phase II study of capecitabine in paclitaxel-refractory metastatic breast cancer. J Clin Oncol 1999;17:485-93.
    • (1999) J Clin Oncol , vol.17 , pp. 485-493
    • Blum, J.L.1    Jones, S.E.2    Buzdar, A.U.3    LoRusso, P.M.4    Kuter, I.5    Vogel, C.6
  • 16
    • 0024536437 scopus 로고
    • Optimal two-stage designs for phase II clinical trials
    • Simon R. Optimal two-stage designs for phase II clinical trials. Control Clin Trials 1989;10:1-10.
    • (1989) Control Clin Trials , vol.10 , pp. 1-10
    • Simon, R.1
  • 17
    • 33645269821 scopus 로고    scopus 로고
    • Triplet therapy with oxaliplatin irinotecan 5-fluorouracil and folinic acid within a combined modality approach in patients with liver metastases from colorectal cancer
    • abstr 3593
    • de la Camara J, Rodriguez J, Rotellar F, Viudez F. Triplet therapy with oxaliplatin, irinotecan, 5-fluorouracil and folinic acid within a combined modality approach in patients with liver metastases from colorectal cancer. Proc Am Soc Clin Oncol 2004;23: abstr 3593.
    • (2004) Proc Am Soc Clin Oncol , vol.23
    • de la Camara, J.1    Rodriguez, J.2    Rotellar, F.3    Viudez, F.4
  • 18
    • 14344258800 scopus 로고    scopus 로고
    • Resection of previously unresectable liver metastases from colorectal cancer (LMCRC) after chemotherapy (CT) with CPT-11/L-OHP/LV5FU (Folfirinox): a prospective phase II trial
    • abstr 3613
    • Quenet F, Nordlinger B, Rivoire M, Delpero J, Portier G, Ychou M, et al. Resection of previously unresectable liver metastases from colorectal cancer (LMCRC) after chemotherapy (CT) with CPT-11/L-OHP/LV5FU (Folfirinox): a prospective phase II trial. Proc Am Soc Clin Oncol 2004;23: abstr 3613.
    • (2004) Proc Am Soc Clin Oncol , vol.23
    • Quenet, F.1    Nordlinger, B.2    Rivoire, M.3    Delpero, J.4    Portier, G.5    Ychou, M.6
  • 19
    • 10744229419 scopus 로고    scopus 로고
    • Multimodal therapy with intravenous biweekly leucovorin, 5-fluorouracil and irinotecan combined with hepatic arterial infusion pirarubicin in non-resectable hepatic metastases from colorectal cancer (a European Association for Research in Oncology trial)
    • Zelek L, Bugat R, Cherqui D, Ganem G, Valleur P, Guimbaud R, et al. Multimodal therapy with intravenous biweekly leucovorin, 5-fluorouracil and irinotecan combined with hepatic arterial infusion pirarubicin in non-resectable hepatic metastases from colorectal cancer (a European Association for Research in Oncology trial). Ann Oncol 2003;14:1537-42.
    • (2003) Ann Oncol , vol.14 , pp. 1537-1542
    • Zelek, L.1    Bugat, R.2    Cherqui, D.3    Ganem, G.4    Valleur, P.5    Guimbaud, R.6
  • 20
    • 2642541197 scopus 로고    scopus 로고
    • Neoadjuvant treatment of unresectable liver disease with irinotecan and 5-fluorouracil plus folinic acid in colorectal cancer patients
    • Pozzo C, Basso M, Cassano A, Quirino M, Schinzari G, Trigila N, et al. Neoadjuvant treatment of unresectable liver disease with irinotecan and 5-fluorouracil plus folinic acid in colorectal cancer patients. Ann Oncol 2004;15:933-9.
    • (2004) Ann Oncol , vol.15 , pp. 933-939
    • Pozzo, C.1    Basso, M.2    Cassano, A.3    Quirino, M.4    Schinzari, G.5    Trigila, N.6
  • 21
    • 33644819672 scopus 로고    scopus 로고
    • Oxaliplatin, fluorouracil, and leucovorin for patients with unresectable liver-only metastases from colorectal cancer: a North Central Cancer Treatment Group phase II study
    • Alberts SR, Horvath WL, Sternfeld WC, Goldberg RM, Mahoney MR, Dakhil SR, et al. Oxaliplatin, fluorouracil, and leucovorin for patients with unresectable liver-only metastases from colorectal cancer: a North Central Cancer Treatment Group phase II study. J Clin Oncol 2005;23:9243-9.
    • (2005) J Clin Oncol , vol.23 , pp. 9243-9249
    • Alberts, S.R.1    Horvath, W.L.2    Sternfeld, W.C.3    Goldberg, R.M.4    Mahoney, M.R.5    Dakhil, S.R.6
  • 22
    • 0029794696 scopus 로고    scopus 로고
    • Resection of nonresectable liver metastases from colorectal cancer after neoadjuvant chemotherapy
    • Bismuth H, Adam R, Lévi F, Farabos C, Waechter F, Castaing D, et al. Resection of nonresectable liver metastases from colorectal cancer after neoadjuvant chemotherapy. Ann Surg 1996;224:509-20.
    • (1996) Ann Surg , vol.224 , pp. 509-520
    • Bismuth, H.1    Adam, R.2    Lévi, F.3    Farabos, C.4    Waechter, F.5    Castaing, D.6
  • 23
    • 4644320061 scopus 로고    scopus 로고
    • Rescue surgery for unresectable colorectal liver metastases downstaged by chemotherapy: a model to predict long-term survival
    • Adam R, Delvart V, Pascal G, Valeanu A, Castaing D, Azoulay D, et al. Rescue surgery for unresectable colorectal liver metastases downstaged by chemotherapy: a model to predict long-term survival. Ann Surg 2004;240:644-57.
    • (2004) Ann Surg , vol.240 , pp. 644-657
    • Adam, R.1    Delvart, V.2    Pascal, G.3    Valeanu, A.4    Castaing, D.5    Azoulay, D.6
  • 24
    • 21344466292 scopus 로고    scopus 로고
    • Multicenter phase II study of oral capecitabine plus irinotecan as first-line chemotherapy in advanced colorectal cancer: a Korean Cancer Study Group trial
    • Kim TW, Kang WK, Chang HM, Park JO, Ryoo BY, Ahn JS, et al. Multicenter phase II study of oral capecitabine plus irinotecan as first-line chemotherapy in advanced colorectal cancer: a Korean Cancer Study Group trial. Acta Oncol 2005;44:230-5.
    • (2005) Acta Oncol , vol.44 , pp. 230-235
    • Kim, T.W.1    Kang, W.K.2    Chang, H.M.3    Park, J.O.4    Ryoo, B.Y.5    Ahn, J.S.6
  • 25
    • 45949094172 scopus 로고    scopus 로고
    • Irinotecan plus capecitabine as first-line chemotherapy in advanced colorectal cancer
    • Gennatas C, Michalaki V, Gennatas S, Papalambros E. Irinotecan plus capecitabine as first-line chemotherapy in advanced colorectal cancer. Anticancer Res 2008;28:1923-6.
    • (2008) Anticancer Res , vol.28 , pp. 1923-1926
    • Gennatas, C.1    Michalaki, V.2    Gennatas, S.3    Papalambros, E.4
  • 26
    • 39049165189 scopus 로고    scopus 로고
    • Efficacy of combination chemotherapy with irinotecan (CPT-11) plus capecitabine in patients with metastatic or advanced colorectal carcinoma-a dual-centre phase II study: the MAC-6
    • Choi CK, Chan RT, Tung SY, Lui L, Siu S, Au GK, et al. Efficacy of combination chemotherapy with irinotecan (CPT-11) plus capecitabine in patients with metastatic or advanced colorectal carcinoma-a dual-centre phase II study: the MAC-6. Clin Oncol(R Coll Radiol) 2008;20:168-75.
    • (2008) Clin Oncol(R Coll Radiol) , vol.20 , pp. 168-175
    • Choi, C.K.1    Chan, R.T.2    Tung, S.Y.3    Lui, L.4    Siu, S.5    Au, G.K.6
  • 27
    • 0035698112 scopus 로고    scopus 로고
    • Impact of surgery on survival in palliative patients with metastatic colorectal cancer after first line treatment with weekly 24-hour infusion of high-dose 5-fluorouracil and folinic acid
    • Wein A, Riedel C, Köckerling F, Martus P, Baum U, Brueckl WM, et al. Impact of surgery on survival in palliative patients with metastatic colorectal cancer after first line treatment with weekly 24-hour infusion of high-dose 5-fluorouracil and folinic acid. Ann Oncol 2001;12:1721-7.
    • (2001) Ann Oncol , vol.12 , pp. 1721-1727
    • Wein, A.1    Riedel, C.2    Köckerling, F.3    Martus, P.4    Baum, U.5    Brueckl, W.M.6
  • 28
    • 0036889745 scopus 로고    scopus 로고
    • Combination of neoadjuvant chemotherapy with cryotherapy and surgical resection for the treatment of unresectable liver metastases from colorectal carcinoma
    • Rivoire M, De Cian F, Meeus P, Négrier S, Sebban H, Kaemmerlen P. Combination of neoadjuvant chemotherapy with cryotherapy and surgical resection for the treatment of unresectable liver metastases from colorectal carcinoma. Cancer 2002;95:2283-92.
    • (2002) Cancer , vol.95 , pp. 2283-2292
    • Rivoire, M.1    De Cian, F.2    Meeus, P.3    Négrier, S.4    Sebban, H.5    Kaemmerlen, P.6
  • 29
    • 4143148621 scopus 로고    scopus 로고
    • Dose-finding study of weekly 24-h continuous infusion of 5-fluorouracil associated with alternating oxaliplatin or irinotecan in advanced colorectal cancer patients
    • CalsL,RixeO,François E, Favre R, Merad L, Deplanque G, et al. Dose-finding study of weekly 24-h continuous infusion of 5-fluorouracil associated with alternating oxaliplatin or irinotecan in advanced colorectal cancer patients. Ann Oncol 2004;15:1018-24.
    • (2004) Ann Oncol , vol.15 , pp. 1018-1024
    • CalsL RixeO François, E.1    Favre, R.2    Merad, L.3    Deplanque, G.4
  • 30
    • 23844544714 scopus 로고    scopus 로고
    • Liver resection after irinotecan, 5-fluorouracil, and folinic acid for patients with unresectable colorectal liver metastases: a multicenter phase II study by the Cancer Therapeutic Research Group
    • Ho WM, Ma B, Mok T, Yeo W, Lai P, Lim R, et al. Liver resection after irinotecan, 5-fluorouracil, and folinic acid for patients with unresectable colorectal liver metastases: a multicenter phase II study by the Cancer Therapeutic Research Group. Med Oncol 2005;22:303-12.
    • (2005) Med Oncol , vol.22 , pp. 303-312
    • Ho, W.M.1    Ma, B.2    Mok, T.3    Yeo, W.4    Lai, P.5    Lim, R.6
  • 31
    • 20044370825 scopus 로고    scopus 로고
    • Oxaliplatin combined with irinotecan and 5-fluorouracil/leucovorin (OCFL) in metastatic colorectal cancer: a phase I-II study
    • Seium Y, Stupp R, Ruhstaller T, Gervaz P, Mentha G, Philippe M, et al. Oxaliplatin combined with irinotecan and 5-fluorouracil/leucovorin (OCFL) in metastatic colorectal cancer: a phase I-II study. Ann Oncol 2005;16:762-6.
    • (2005) Ann Oncol , vol.16 , pp. 762-766
    • Seium, Y.1    Stupp, R.2    Ruhstaller, T.3    Gervaz, P.4    Mentha, G.5    Philippe, M.6
  • 32
    • 20144389169 scopus 로고    scopus 로고
    • Chemotherapy permits resection of metastatic colorectal cancer: experience from Intergroup N9741
    • Delaunoit T, Alberts SR, Sargent DJ, Green E, Goldberg RM, Krook J, et al. Chemotherapy permits resection of metastatic colorectal cancer: experience from Intergroup N9741. Ann Oncol 2005;16:425-9.
    • (2005) Ann Oncol , vol.16 , pp. 425-429
    • Delaunoit, T.1    Alberts, S.R.2    Sargent, D.J.3    Green, E.4    Goldberg, R.M.5    Krook, J.6
  • 33
    • 30944445619 scopus 로고    scopus 로고
    • Treatment with 5-fluorouracil/folinic acid, oxaliplatin, and irinotecan enables surgical resection of metastases in patients with initially unresectable metastatic colorectal cancer
    • Masi G, Cupini S, Marcucci L, Cerri E, Loupakis F, Allegrini G, et al. Treatment with 5-fluorouracil/folinic acid, oxaliplatin, and irinotecan enables surgical resection of metastases in patients with initially unresectable metastatic colorectal cancer. Ann Surg Oncol 2006;13:58-65.
    • (2006) Ann Surg Oncol , vol.13 , pp. 58-65
    • Masi, G.1    Cupini, S.2    Marcucci, L.3    Cerri, E.4    Loupakis, F.5    Allegrini, G.6
  • 34
    • 36749103860 scopus 로고    scopus 로고
    • Neoadjuvant treatment before resection of liver metastases
    • Benoist S, Nordlinger B. Neoadjuvant treatment before resection of liver metastases. Eur J Surg Oncol 2007;33(Suppl 2):S35-41.
    • (2007) Eur J Surg Oncol , vol.33 , Issue.SUPPL 2
    • Benoist, S.1    Nordlinger, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.