Developmental function of HMGN proteins

Biochimica et Biophysica Acta - Gene Regulatory Mechanisms

Volumn 1799, Issue 1-2, 2010, Pages 69-73

  Furusawa, Takashi ^a   Cherukuri, Srujana ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Chromatin; Differentiation; Embryogenesis; HMGN protein

Indexed keywords

HIGH MOBILITY GROUP B3 PROTEIN; HIGH MOBILITY GROUP N PROTEIN; HIGH MOBILITY GROUP N1 PROTEIN; HIGH MOBILITY GROUP N2 PROTEIN; HISTONE;

CELL DIFFERENTIATION; CELL MATURATION; CHROMATIN STRUCTURE; EMBRYO DEVELOPMENT; EPIGENETICS; EXPERIMENT; GENE STRUCTURE; IN VIVO STUDY; NONHUMAN; NUCLEOSOME; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN PROCESSING; REVIEW;

ANIMALS; CELL DIFFERENTIATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GROWTH AND DEVELOPMENT; HMGN PROTEINS; HUMANS;

EID: 74849102179     PISSN: 18749399     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbagrm.2009.11.011     Document Type: Review

References (44)

1. Hock R., Furusawa T., Ueda T., and Bustin M. HMG chromosomal proteins in development and disease. Trends Cell Biol. 17 (2007) 72-79
2. Bustin M. Chromatin unfolding and activation by HMGN(*) chromosomal proteins. Trends Biochem. Sci. 26 (2001) 431-437
3. Rochman M., Postnikov Y., Correll S., Malicet C., Wincovitch S., Karpova T.S., McNally J.G., Wu X., Bubunenko N.A., Grigoryev S., and Bustin M. The interaction of NSBP1/HMGN5 with nucleosomes in euchromatin counteracts linker histone-mediated chromatin compaction and modulates transcription. Mol. Cell 35 (2009) 642-656
4. Shirakawa H., Landsman D., Postnikov Y.V., and Bustin M. NBP-45, a novel nucleosomal binding protein with a tissue-specific and developmentally regulated expression. J. Biol. Chem. 275 (2000) 6368-6374
5. Strichman-Almashanu L.Z., Bustin M., and Landsman D. Retroposed copies of the HMG genes: a window to genome dynamics. Genome Res. 13 (2003) 800-812
6. Furusawa T., Lim J.H., Catez F., Birger Y., Mackem S., and Bustin M. Down-regulation of nucleosomal binding protein HMGN1 expression during embryogenesis modulates Sox9 expression in chondrocytes. Mol. Cell. Biol. 26 (2006) 592-604
7. Lehtonen S., and Lehtonen E. HMG-17 is an early marker of inductive interactions in the developing mouse kidney. Differentiation 67 (2001) 154-163
8. Crippa M.P., Nickol J.M., and Bustin M. Developmental changes in the expression of high mobility group chromosomal proteins. J. Biol. Chem. 266 (1991) 2712-2714
9. Pash J.M., Bhorjee J.S., Patterson B.M., and Bustin M. Persistence of chromosomal proteins HMG-14/-17 in myotubes following differentiation-dependent reduction of HMG mRNA. J. Biol. Chem. 265 (1990) 4197-4199
10. Furusawa T., Ko J.H., Birger Y., and Bustin M. Expression of nucleosomal protein HMGN1 in the cycling mouse hair follicle. Gene Expr. Patterns 9 (2009) 289-295
11. Pash J.M., Alfonso P.J., and Bustin M. Aberrant expression of high mobility group chromosomal protein 14 affects cellular differentiation. J. Biol. Chem. 268 (1993) 13632-13638
12. Birger Y., Catez F., Furusawa T., Lim J.H., Prymakowska-Bosak M., West K.L., Postnikov Y.V., Haines D.C., and Bustin M. Increased tumorigenicity and sensitivity to ionizing radiation upon loss of chromosomal protein HMGN1. Cancer Res. 65 (2005) 6711-6718
13. Birger Y., West K.L., Postnikov Y.V., Lim J.H., Furusawa T., Wagner J.P., Laufer C.S., Kraemer K.H., and Bustin M. Chromosomal protein HMGN1 enhances the rate of DNA repair in chromatin. EMBO J. 22 (2003) 1665-1675
14. Fousteri M., Vermeulen W., van Zeeland A.A., and Mullenders L.H. Cockayne syndrome A and B proteins differentially regulate recruitment of chromatin remodeling and repair factors to stalled RNA polymerase II in vivo. Mol. Cell 23 (2006) 471-482
15. Kim Y.C., Gerlitz G., Furusawa T., Catez F., Nussenzweig A., Oh K.S., Kraemer K.H., Shiloh Y., and Bustin M. Activation of ATM depends on chromatin interactions occurring before induction of DNA damage. Nat. Cell Biol. 11 (2009) 92-96
16. Birger Y., Davis J., Furusawa T., Rand E., Piatigorsky J., and Bustin M. A role for chromosomal protein HMGN1 in corneal maturation. Differentiation 74 (2006) 19-29
17. Hill D.A., and Imbalzano A.N. HMGN1 is dispensable for myogenesis and adipogenesis. Gene 371 (2006) 59-67
18. Hoogendam J., Farih-Sips H., van Beek E., Lowik C.W., Wit J.M., and Karperien M. Novel late response genes of PTHrP in chondrocytes. Horm. Res. 67 (2007) 159-170
19. Mohamed O.A., Bustin M., and Clarke H.J. High-mobility group proteins 14 and 17 maintain the timing of early embryonic development in the mouse. Dev. Biol. 229 (2001) 237-249
20. Vigneault C., McGraw S., Massicotte L., and Sirard M.A. Transcription factor expression patterns in bovine in vitro-derived embryos prior to maternal-zygotic transition. Biol. Reprod. 70 (2004) 1701-1709
21. Bastos G.M., Goncalves P.B., and Bordignon V. Immunolocalization of the high-mobility group N2 protein and acetylated histone H3K14 in early developing parthenogenetic bovine embryos derived from oocytes of high and low developmental competence. Mol. Reprod. Dev. 75 (2008) 282-290
22. Korner U., Bustin M., Scheer U., and Hock R. Developmental role of HMGN proteins in Xenopus laevis. Mech. Dev. 120 (2003) 1177-1192
23. Pash J., Popescu N., Matocha M., Rapoport S., and Bustin M. Chromosomal protein HMG-14 gene maps to the Down syndrome region of human chromosome 21 and is overexpressed in mouse trisomy 16. Proc. Natl. Acad. Sci. U. S. A. 87 (1990) 3836-3840
24. Potier M.C., Rivals I., Mercier G., Ettwiller L., Moldrich R.X., Laffaire J., Personnaz L., Rossier J., and Dauphinot L. Transcriptional disruptions in Down syndrome: a case study in the Ts1Cje mouse cerebellum during post-natal development. J. Neurochem. 97 Suppl 1 (2006) 104-109
25. West K.L., Ito Y., Birger Y., Postnikov Y., Shirakawa H., and Bustin M. HMGN3a and HMGN3b, two protein isoforms with a tissue-specific expression pattern, expand the cellular repertoire of nucleosome-binding proteins. J. Biol. Chem. 276 (2001) 25959-25969
26. Ito Y., and Bustin M. Immunohistochemical localization of the nucleosome-binding protein HMGN3 in mouse brain. J. Histochem. Cytochem. 50 (2002) 1273-1275
27. Lucey M.M., Wang Y., Bustin M., and Duncan M.K. Differential expression of the HMGN family of chromatin proteins during ocular development. Gene Expr. Patterns 8 (2008) 433-437
28. Ueda T., Furusawa T., Kurahashi T., Tessarollo L., and Bustin M. The nucleosome binding protein HMGN3 modulates the transcription profile of pancreatic {beta}-cells and affects insulin secretion. Mol. Cell. Biol. 29 (2009) 5264-5275
29. Shi J., Levinson D.F., Duan J., Sanders A.R., Zheng Y., Pe'er I., Dudbridge F., Holmans P.A., Whittemore A.S., Mowry B.J., Olincy A., Amin F., Cloninger C.R., Silverman J.M., Buccola N.G., Byerley W.F., Black D.W., Crowe R.R., Oksenberg J.R., Mirel D.B., Kendler K.S., Freedman R., and Gejman P.V. Common variants on chromosome 6p22.1 are associated with schizophrenia. Nature 460 (2009) 753-757
30. Birger Y., Ito Y., West K.L., Landsman D., and Bustin M. HMGN4, a newly discovered nucleosome-binding protein encoded by an intronless gene. DNA Cell Biol. 20 (2001) 257-264
31. Shirakawa H., Rochman M., Furusawa T., Kuehn M.R., Horigome S., Haketa K., Sugita Y., Inada T., Komai M., and Bustin M. The nucleosomal binding protein NSBP1 is highly expressed in the placenta and modulates the expression of differentiation markers in placental Rcho-1 cells. J. Cell. Biochem. 106 (2009) 651-658
32. Tang W.Y., Newbold R., Mardilovich K., Jefferson W., Cheng R.Y., Medvedovic M., and Ho S.M. Persistent hypomethylation in the promoter of nucleosomal binding protein 1 (Nsbp1) correlates with overexpression of Nsbp1 in mouse uteri neonatally exposed to diethylstilbestrol or genistein. Endocrinology 149 (2008) 5922-5931
33. Lehtonen S., Olkkonen V.M., Stapleton M., Zerial M., and Lehtonen E. HMG-17, a chromosomal non-histone protein, shows developmental regulation during organogenesis. Int. J. Dev. Biol. 42 (1998) 775-782
34. Ueda T., Postnikov Y.V., and Bustin M. Distinct domains in high mobility group N variants modulate specific chromatin modifications. J. Biol. Chem. 281 (2006) 10182-10187
35. Rubinstein Y.R., Furusawa T., Lim J.H., Postnikov Y.V., West K.L., Birger Y., Lee S., Nguyen P., Trepel J.B., and Bustin M. Chromosomal protein HMGN1 modulates the expression of N-cadherin. FEBS J. 272 (2005) 5853-5863
36. West K.L., Castellini M.A., Duncan M.K., and Bustin M. Chromosomal proteins HMGN3a and HMGN3b regulate the expression of glycine transporter 1. Mol. Cell. Biol. 24 (2004) 3747-3756
37. Amen M., Espinoza H.M., Cox C., Liang X., Wang J., Link T.M., Brennan R.G., Martin J.F., and Amendt B.A. Chromatin-associated HMG-17 is a major regulator of homeodomain transcription factor activity modulated by Wnt/beta-catenin signaling. Nucleic Acids Res. 36 (2008) 462-476
38. Zhu N., and Hansen U. HMGN1 modulates estrogen-mediated transcriptional activation through interactions with specific DNA-binding transcription factors. Mol. Cell. Biol. 27 (2007) 8859-8873
39. Catez F., Yang H., Tracey K.J., Reeves R., Misteli T., and Bustin M. Network of dynamic interactions between histone H1 and high-mobility-group proteins in chromatin. Mol. Cell. Biol. 24 (2004) 4321-4328
40. Fan Y., Sirotkin A., Russell R.G., Ayala J., and Skoultchi A.I. Individual somatic H1 subtypes are dispensable for mouse development even in mice lacking the H1(0) replacement subtype. Mol. Cell. Biol. 21 (2001) 7933-7943
41. Fan Y., Nikitina A., Moren-Kensicki E.M., Zhao J., Magnuson T.R., Woodcock C.L., and Skoultchi A.I. H1 linker histones are essential for mouse development and affect nucleosome spacing in vivo. Mol. Cell. Biol. 23 (2003) 4559-4572
42. Fan Y., Nikitina T., Zhao J., Fleury T.J., Bhattacharyya R., Bouhassira E.E., Stein A., Woodcock C.L., and Skoultchi A.I. Histone H1 depletion in mammals alters global chromatin structure but causes specific changes in gene regulation. Cell 123 (2005) 1199-1212
43. Lim J.H., Catez F., Birger Y., West K.L., Prymakowska-Bosak M., Postnikov Y.V., and Bustin M. Chromosomal protein HMGN1 modulates histone H3 phosphorylation. Mol. Cell 15 (2004) 573-584
44. Steinbach O.C., Wolffe A.P., and Rupp R.A. Somatic linker histones cause loss of mesodermal competence in Xenopus. Nature 389 (1997) 395-399