Effects of endogenous glucocorticoids on allergic inflammation and T H1/TH2 balance in airway allergic disease

Annals of Allergy, Asthma and Immunology

Volumn 103, Issue 6, 2009, Pages 525-534

  Suqin, Zhang ^a   Ziyin, Shen ^a   Guorang, Hu ^b   Runhong, Liu ^a   Xinmin, Zhang ^a  

^a FUDAN UNIVERSITY   (China)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; INTERLEUKIN 4; INTERLEUKIN 5; METYRAPONE; MIFEPRISTONE; OVALBUMIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD; BONE MARROW; CELL COUNT; CONTROLLED STUDY; CORTICOSTEROID RELEASE; DISEASE SEVERITY; DOWN REGULATION; DRUG INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; EOSINOPHIL; EOSINOPHIL COUNT; FLOW CYTOMETRY; IMMUNE RESPONSE; INJECTION; LUNG; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY TRACT ALLERGY; SENSITIZATION; SNEEZING; SPLEEN CELL; SUPERNATANT; TH1 CELL; TH2 CELL; UPREGULATION;

EID: 74749108409     PISSN: 10811206     EISSN: 15344436     Source Type: Journal    
DOI: 10.1016/S1081-1206(10)60270-0     Document Type: Article

References (45)

1. Quraishi SA, Davies MJ, Craig TJ. Inflammatory responses in allergic rhinitis: traditional approaches and novel treatment strategies. J Am Osteopath Assoc. 2004;104(5 suppl 5):S7-S15.
2. Bochner BS, Busse WW. Allergy and asthma. J Allergy Clin Immunol. 2005;115:953-959.
3. Kroegel C, Costabel U. Immune functions of constitutive pulmonary cells: the salt in the soup. Eur Respir J. 1994;7:2106-2107.
4. Krouse JH, Brown RW, Fineman SM, et al. Asthma and the unified airway. Otolaryngol Head Neck Surg. 2007;136(5 suppl):S75-S106.
5. Ciprandi G, Cirillo I. The lower airway pathology of rhinitis. J Allergy Clin Immunol. 2006;118:1105-1109.
6. Busse WW, Coffman RL, Gelfand EW, Kay AB, Rosenwasser LJ. Mechanisms of persistent airway inflammation in asthma: a role for T-cells and T-cell products. Am J Respir Crit Care Med. 1995;152: 388-393.
7. Cher DJ, Mosmann TR. Two types of murine helper T-cell clone: delayed-type hypersensitivity is mediated by Th1 clones. J Immunol. 1987;138:3688-3694.
8. Mosmann TR, Coffman RL. Th1-cell and Th2-cell: different patterns of lymphokine secretion lead to different functional-properties. Ann Rev Immunol. 1989;7:145-173.
9. Finkelman FD, Katona IM, Urban JF Jr, et al. IL-4 is required to generate and sustain in vivo IgE responses. J Immunol. 1988;141: 2335-2341.
10. Lopez AF, Sanderson CJ, Gamble JR, Campbell HD, Young IG, Vadas MA. Recombinant human interleukin-5 is a selective activator of human eosinophil function. J Exp Med. 1988;167:219-224.
11. Gajewski TF, Joyce J, Fitch FW. Antiproliferative effect of IFN-gamma in immune regulation: differential selection of Th1 and Th2 murine helper lymphocyte-T clones using recombinant IL-2 and recombinant IFN-gamma. J Immunol. 1989;143:15-22.
12. Webster JI, Tonelli L, Sternberg EM. Neuroendocrine regulation of immunity. Ann Rev Immunol. 2002;20:125-163.
13. Adcock IM.. Molecular mechanisms of glucocorticosteroid actions. Pulm Pharmacol Ther. 2000;13:115-126.
14. Barnes PJ, Adcock IM. Transcription factors and asthma. Eur Respir J. 1998;12:221-234.
15. Chrousos GP. Seminars in Medicine of the Beth-Israel-Hospital, Boston: the hypothalamic-pituitary-adrenal axis and immune-mediated inflammation. N Engl J Med. 1995;332:1351-1362.
16. Sasaki H, Yanai M, Shimura S, et al. Late asthmatic response to ascaris antigen challenge in dogs treated with metyrapone. Am Rev Respir Dis. 1987;136:1459-1465.
17. Herrscher RF, Kasper C, Sullivan TJ. Endogenous cortisol regulates immunoglobulin E-dependent late phase reactions. J Clin Invest. 1992; 90:596-603.
18. Peebles RS Jr, Togias A, Bickel CA, Diemer FB, Hubbardk WC, Schleimer RP. Endogenous glucocorticoids and antigen-induced acute and late phase pulmonary responses. Clin Exp Allergy. 2000;30: 1257-1265.
19. Donley MP, Schulkin J, Rosen JB. Glucocorticoid receptor antagonism in the basolateral amygdala and ventral hippocampus interferes with long-term memory of contextual fear. Behav Brain Res. 2005;164: 197-205.
20. Heikinheimo O, Kekkonen R. Dose-response relationships of Ru-486. Ann Med. 1993;25:71-76.
21. Lähteenmäki P, Heikinheimo O, Croxatto H, et al. Pharmacokinetics and metabolism of Ru-486. J Steroid Biochem. 1987;27:859-863.
22. Kawai S, Nieman LK, Brandon DD, et al. Pharmacokinetic properties of the antiglucocorticoid and antiprogesterone steroid Ru 486 in man. J Pharmacol Exp Ther. 1987;241:401-406.
23. Georén S, Ahnblad P, Stjärne P, Wikström AC, Stierna P. Significance of endogenous glucocorticoid sensitivity for airway eosinophilia in a murine model of allergy. Acta Otolaryngol. 2005;125:378-385.
24. De Bie JJ, Hessel EM, Van Ark I, et al. Effect of dexamethasone and endogenous corticosterone on airway hyperresponsiveness and eosinophilia in the mouse. Br J Pharmacol. 1996;119:1484-1490.
25. Sternberg EM, Hill JM, Chrousos GP, et al. Inflammatory mediator-induced hypothalamic pituitary-adrenal axis activation is defective in streptococcal cell-wall arthritis-susceptible Lewis rats. Proc Natl Acad Sci U S A. 1989;86:2374-2378.
26. Wei RT, Listwak SJ, Sternberg EM. Lewis hypothalamic cells constitutively and upon stimulation express higher levels of mRNA for pro-inflammatory cytokines and related molecules: comparison with inflammatory resistant Fischer rat hypothalamic cells. J Neuroimmunol. 2003; 135:10-28.
27. Eum SY, Créminon C, Hailé S, Lefort J, Vargaftig BB. Inhibition of airways inflammation by dexamethasone is followed by reduced bronchial hyperreactivity in BP2 mice. Clin Exp Allergy. 1996;26: 971-979.
28. Kauffmann F, Guiochon-Mantel A, Neukirch F. Is low endogenous cortisol a risk factor for asthma? Am J Respir Crit Care Med. 1999;160: 1428-1428.
29. Landstra AM, Postma DS, Boezen HM, van Aalderen WM. Role of serum cortisol levels in children with asthma. Am J Respir Crit Care Med. 2002;165:708-712.
30. Buske-Kirschbaum A, von Auer K, Krieger S, Weis S, Rauh W, Hellhammer D. Blunted cortisol responses to psychosocial stress in asthmatic children: a general feature of atopic disease? Psychosom Med. 2003;65:806-810.
31. Wamboldt MZ, Laudenslager M, Wamboldt FS, Kelsay K, Hewitt J. Adolescents with atopic disorders have an attenuated cortisol response to laboratory stress. J Allergy Clin Immunol. 2003;111:509-514.
32. Silverman ES, Breault DT, Vallone J, et al. Corticotropin-releasing hormone deficiency increases allergen-induced airway inflammation in a mouse model of asthma. J Allergy Clin Immunol. 2004;114:747-754.
33. Elenkov IJ. Glucocorticoids and the Th1/Th2 balance. Ann N Y Acad Sci. 2004;1024:138-146.
34. Tsitoura DC, DeKruyff RH, Lamb JR, Umetsu DT. Intranasal exposure to protein antigen induces immunological tolerance mediated by functionally disabled CD4(+) T cells. J Immunol. 1999;163:2592-2600.
35. Tsitoura DC, Blumenthal RL, Berry G, Dekruyff RH, Umetsu DT. Mechanisms preventing allergen-induced airways hyperreactivity: role of tolerance and immune deviation. J Allergy Clin Immunol. 2000;106: 239-246.
36. McCusker C, Chicoine M, Hamid Q, Mazer B. Site-specific sensitization in a murine model of allergic rhinitis: role of the upper airway in lower airways disease. J Allergy Clin Immunol. 2002;110:891-898.
37. Randolph DA, Stephens R, Carruthers CJ, Chaplin DD. Cooperation between Th1 and Th2 cells in a murine model of eosinophilic airway inflammation. J Clin Invest. 1999;104:1021-1029.
38. Ford JG, Rennick D, Donaldson DD, et al. IL-13 and IFN-gamma: interactions in lung inflammation. J Immunol. 2001;167:1769-1777.
39. Cui J, Pazdziorko S, Miyashiro JS, et al. TH1-mediated airway hyper-responsiveness independent of neutrophilic inflammation. J Allergy Clin Immunol. 2005;115:309-315.
40. Nomura S, Fujitaka M, Sakura N, Ueda K. Adrenocortical function in asthmatic children: low levels of adrenocortical hormones in children with persistent attacks. Eur J Pediatr. 1997;156:323-328.
41. Shannon J, Ernst P, Yamauchi Y, et al. Differences in airway cytokine profile in severe asthma compared to moderate asthma. Chest. 2008; 133:420-426.
42. Flood-Page PT, Menzies-Gow AN, Kay AB, Robinson DS. Eosinophil's role remains uncertain as anti-interleukin-5 only partially depletes numbers in asthmatic airway. Am J Respir Crit Care Med. 2003;167: 199-204.
43. Miller GE, Gaudin A, Zysk E, Chen E. Parental support and cytokine activity in childhood asthma: the role of glucocorticoid sensitivity. J Allergy Clin Immunol. 2009;123:824-830.
44. Robinson DS, Hamid Q, Ying S, et al. Predominant Th2-Like bronchoalveolar lymphocyte-T population in atopic asthma. N Engl J Med. 1992;326:298-304.
45. Asquith KL, Ramshaw HS, Hansbro PM, Beagley KW, Lopez AF, Foster PS. The IL-3/IL-5/GM-CSF common beta receptor plays a pivotal role in the regulation of Th2 immunity and allergic airway inflammation. J Immunol. 2008;180:1199-1206.