On the use of N-dicyclopropylmethyl aspartyl-glycine synthone for backbone amide protection

Journal of Peptide Science

Volumn 16, Issue 1, 2010, Pages 65-70

  Röder, René ^a,b   Henklein, Petra ^b   HardyWeisshoff ^c   Mugge, Clemens ^c   Pätzel, Michael ^c   Schubert, Ulrich ^a   Carpinod, Louis A ^d   Henklein, Peter ^b  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c HUMBOLDT UNIVERSITY   (Germany)

^d UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

Acid labile dicyclopropylmethyl group; Asp gly sequence motif; Aspartimide formation; Backbone amide protection

Indexed keywords

2 HYDROXY 4 METHOXYBENZYL DERIVATIVE; 2,2,4,6,7 PENTAMETHYLDIHYDROBENZOFURANE 5 SULFONYL DERIVATIVE; AMIDE; AMINO TERMINAL TELOPEPTIDE; ASPARTIC ACID DERIVATIVE; ASPARTIMIDE; BENZOFURAN DERIVATIVE; BENZYL DERIVATIVE; BIOTIN DERIVATIVE; BIOTINYL ARGINYLGLUTAMINYLTYROSYLARGINYLLEUCYLISOLEUCYLVALYLHISTIDYLASPARAGINYLGLYCYLTYRO SYLCYSTEINYLASPARTYLARGINYLSERYLGLUTAMYLARGINYLASPARAGINYLLEUCINE; CARBONYL DERIVATIVE; DIPEPTIDE; ESTER DERIVATIVE; ETHER DERIVATIVE; GLYCINE DERIVATIVE; IMIDE; N DICYCLOPROPYLMETHYLASPARTYLGLYCINE DERIVATIVE; PEPTIDE; PEPTIDE DERIVATIVE; RESIN; TERT BUTYL ESTER DERIVATIVE; TERT BUTYL ETHER DERIVATIVE; TERT BUTYLOXYCARBONYL DERIVATIVE; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; BIOTINYLATION; CHEMICAL REACTION; CHEMICAL STRUCTURE; DEPROTECTION REACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOMERIZATION; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NUCLEAR OVERHAUSER EFFECT; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTECTION REACTION; PROTEIN CLEAVAGE; STEREOSPECIFICITY;

AMIDES; AMINO ACID SEQUENCE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIPEPTIDES; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 74749103178     PISSN: 10752617     EISSN: 10991387     Source Type: Journal    
DOI: 10.1002/psc.1196     Document Type: Article

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