Rotator cuff healing and the bone marrow "crimson duvet" from clinical observations to science

Techniques in Shoulder and Elbow Surgery

Volumn 10, Issue 4, 2009, Pages 130-137

  Snyder, Stephen J ^a   Burns, Joseph ^a  

^a SOUTHERN CALIFORNIA ORTHOPEDIC INSTITUTE   (United States)

Author keywords

Bone marrow; Crimson duvet; Growth factors; Rotator cuff healing; Stem cells

Indexed keywords

EID: 74549225609     PISSN: 15239896     EISSN: None     Source Type: Journal    
DOI: 10.1097/BTE.0b013e3181c2a940     Document Type: Review

References (31)

1. Jost B, Zumstein M, Pfirrmann CW, et al. Long-term outcome after structural failure of rotator cuff repairs. J Bone Joint Surg Am. 2006;88:472-479.
2. Galatz LM, Ball CM, Teefey SA, et al. The outcome and repair integrity of completely arthroscopically repaired large and massive rotator cuff tears. J Bone Joint Surg Am. 2004;86:219-224.
3. Uhthoff HK, Sano H Trudel G, et al. Early reactions after reimplantation of the tendon of supraspinatus into bone. J Bone Joint Surg Br. 2000;82:1072-1076.
4. Uhthoff HK, Sarkar K. Surgical repair of rotator cuff rupture, the importance of the subacromial bursa. J Bone Joint Surg Br. 1991; 73:399-401.
5. Day SM, Ostrum RF, Chao EYS, et al. Bone injury, regeneration and repair. In: Buckwalter JA, ed. Orthopaedic Basic Science: Biology and Biomechanics of the Musculoskeletal System. 2nd ed. Rosemont: American Academy of Orthopaedic Surgeons; 2000:378.
6. Steadman JR, Rodkey WG, Rodrigo JJ. Microfracture: surgical technique and rehabilitation to treat chondral defects. Clin Orthop Relat Res. 2001;391(suppl):S362-369.
7. Knutsen G, Engebretsen L, Ludvigsen TC, et al. Autologous chondrocyte implantation compared with microfracture in the knee: a randomized trial. J Bone Joint Surg Am. 2004;86:455-464.
8. Steadman RJ, Rodkey WG, Singleton SB, et al. Microfracture technique for full thickness chondral defects: technique and clinical results. Oper Tech Orthop. 1997;7:300-305.
9. Steadman RJ, Briggs KK, Rodrigo JJ, et al. Outcomes of microfracture for traumatic chondral defects of the knee: average 11-year follow-up. Arthroscopy. 2003;19:477-484.
10. Bae D, Yoon K, Song S. Cartilage healing after microfracture in osteoarthritic knees. Arthroscopy. 2009;22:367-374.
11. Sano H, Uhtoff HK, Backman DS, et al. Structural disorders at the insertion of the supraspinatus tendon. J Bone Joint Surg Br. 1998;80: 720-725.
12. Sano H, Ishii H, Trudel G, et al. Histologic evidence of degeneration at the insertion of 3 rotator cuff tendons: a comparative study with human cadaveric shoulders. J Shoulder Elbow Surg. 1999;8:574-579.
13. Choi HR, Kondo S, Hirose K, et al. Expression and enzymatic activity of MMP-2 during healing process of the acute supraspinatus tendon tear in rabbits. J Orthop Res. 2002;20:927-933.
14. Sano H, Ishii H, Yeadon A, et al. Degeneration at insertion weakens tensile strength of the supraspinatus tendon: a comparative mechanical and histologic study of the bone-tendon complex. J Orthop Res. 1997;15:719-726.
15. Uhthoff HK, Traudel G, Himori K. Relevance of pathology and basic research to the surgeon treating rotator cuff disease. J Orthop Sci. 2003;8:449-456.
16. Ishii H, Brunet JA, Welsh RP, et al. ''Bursal reactions'' in rotator cuff tearing, the impingement syndrome and calcifying tendinitis. J Shoulder Elbow Surg. 1997;6:131-136.
17. Matsumoto F, Uhthoff HK, Trudel G, et al. Delayed tendon reattachment does not reverse atrophy and fat accumulation of the supraspinatus. J Orthop Res. 2002;20:357-363.
18. Zumstein MA, Jost B, Hempel J, et al. The clinical and structural longterm results of open repair of massive tears of the rotator cuff. J Bone Joint Surg Am. 2008;90:2423-2431.
19. Gladstone JN, Bishop JY, Lo IK, et al. Fatty infiltration and atrophy of the rotator cuff do not improve after rotator cuff repair and correlate with poor functional outcome. Am J Sports Med. 2007;35: 719-728.
20. Gerber C, Meyer DC, Schneeberger AG, et al. Effect of tendon release and delayed repair on the structure of the muscles of the rotator cuff: an experimental study in sheep. J Bone Joint Surg Am. 2004;86: 1973-1982.
21. Gerber C, Schneeberger AG, Perren SM, et al. Experimental rotator cuff repair: a preliminary study. J Bone Joint Surg Am. 1999;81: 1281-1290.
22. Garnradt SC, Fealy S, Warren R, et al. Vascularity of the rotator cuff after arthroscopic repair: characterization using contrast-enhanced ultrasound (SS-36). Arthroscopy. 2008;24:e20.
23. Wang DW, Burns J, Getelman MH. Measurement of rotator cuff tear tension in vivo: single versus double-row repair (unpublished data, 2009).
24. Bradley JP, Dyga RM, Donnenberg AD, et al. Characterization of the cellular components of bone marrow aspirate from the humerus. Personal communication.
25. Muschler GF, Boehm C, Easley K. Aspiration to obtain osteoblast progenitor cells from human bone marrow: the influence of aspiration volume. J Bone Joint Surg Am. 1997;79:1699-1709.
26. Muschler GF, Nitto H, Boehm CA, et al. Age- and gender-related changes in the cellularity of human bone marrow and the prevalence of osteoblastic progenitors. J Orthop Res. 2001;19:117-125.
27. McLain RF, Fleming JE, Boehm CA, et al. Aspiration of osteoprogenitor cells for augmenting spinal fusion: comparison of progenitor cell concentrations from the vertebral body and iliac crest. J Bone Joint Surg Am. 2005;87: 2655-2661.
28. Mirowitz SA. Hematopoietic bone marrow within the proximal humeral epiphysis in normal adults: investigation with MR imaging. Radiology. 1993;188: 689-693.
29. Kevy S. Trans 52nd Annual ORS Meeting, 2006; Paper No. 1738.
30. Ponticiello MS. Trans 31st Annual SFB Meeting, 2006; Paper No. 575.
31. Randelli P, Margheritini F, Cabitza P, et al. Release of growth factors after acromioplasty. Knee Surg Sports Traumatol Arthrosc. 2009;17:98-101.