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Volumn 116, Issue 1, 2010, Pages 106-114

Bendamustine is effective therapy in patients with rituximab-refractory, indolent B-cell non-Hodgkin lymphoma: Results from a multicenter study

(11)  Kahl, Brad S a   Bartlett, Nancy L b   Leonard, John P c   Chen, Ling d   Ganjoo, Kristen e   Williams, Michael E f   Czuczman, Myron S g   Robinson, K Sue h   Joyce, Robin i   Van Der Jagt, Richard H j   Cheson, Bruce D k  


Author keywords

B cell lymphoma; Bendamustine; Clinical trial; Non Hodgkin lymphoma; Rituximab refractory

Indexed keywords

BENDAMUSTINE; DEXAMETHASONE; FLUDARABINE; MITOXANTRONE; PREDNISONE; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; RITUXIMAB; TOSITUMOMAB I 131;

EID: 74549225036     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.24714     Document Type: Article
Times cited : (233)

References (29)
  • 1
    • 13244270361 scopus 로고    scopus 로고
    • CVP chemotherapy plus rituximab compared with CVP as first-line treatment for advanced follicular lymphoma
    • Marcus R, Imrie K, Belch A, et al. CVP chemotherapy plus rituximab compared with CVP as first-line treatment for advanced follicular lymphoma. Blood. 2005;105:1417-1423.
    • (2005) Blood , vol.105 , pp. 1417-1423
    • Marcus, R.1    Imrie, K.2    Belch, A.3
  • 2
    • 28544435078 scopus 로고    scopus 로고
    • Frontline therapy with rituximab added to the combination of cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) significantly improves the outcome for patients with advanced-stage follicular lymphoma compared with therapy with CHOP alone: Results of a prospective randomized study of the German Low-Grade Lymphoma Study Group
    • Hiddemann W, Kneba M, Dreyling M, et al. Frontline therapy with rituximab added to the combination of cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) significantly improves the outcome for patients with advanced-stage follicular lymphoma compared with therapy with CHOP alone: results of a prospective randomized study of the German Low-Grade Lymphoma Study Group. Blood. 2005;106:3725-3732.
    • (2005) Blood , vol.106 , pp. 3725-3732
    • Hiddemann, W.1    Kneba, M.2    Dreyling, M.3
  • 3
    • 34249939116 scopus 로고    scopus 로고
    • Rituximab added to first-line mitoxantrone, chlorambucil, and prednisolone chemotherapy followed by interferon maintenance prolongs survival in patients with advanced follicular lymphoma: An East German Study Group Hematology and Oncology Study
    • Herold M, Haas A, Srock S, et al. Rituximab added to first-line mitoxantrone, chlorambucil, and prednisolone chemotherapy followed by interferon maintenance prolongs survival in patients with advanced follicular lymphoma: an East German Study Group Hematology and Oncology Study. J Clin Oncol. 2007;25:1986-1992.
    • (2007) J Clin Oncol , vol.25 , pp. 1986-1992
    • Herold, M.1    Haas, A.2    Srock, S.3
  • 4
    • 33748306360 scopus 로고    scopus 로고
    • Update of the FL2000 randomized trial combining rituximab to CHVP-interferon in follicular lymphoma patients [abstract]
    • June 20, Abstract 7508
    • Foussard C, Mounier N, Van Hoof A, et al. Update of the FL2000 randomized trial combining rituximab to CHVP-interferon in follicular lymphoma patients [abstract]. J Clin Oncol. 2006;18S(June 20 suppl):424. Abstract 7508.
    • (2006) J Clin Oncol , vol.18 S , Issue.SUPPL. , pp. 424
    • Foussard, C.1    Mounier, N.2    Van Hoof, A.3
  • 5
    • 74549220071 scopus 로고    scopus 로고
    • National Comprehensive Cancer Network (NCCN). NCCN Clinical Practice Guidelines in Oncology. Non-Hodgkin's Lymphomas. Version 3.2008. 04/10/08. Available at: http://www.nccn.org/professionals/physician-gls/PDF/nhl.pdf Accessed January 13, 2009.
    • National Comprehensive Cancer Network (NCCN). NCCN Clinical Practice Guidelines in Oncology. Non-Hodgkin's Lymphomas. Version 3.2008. 04/10/08. Available at: http://www.nccn.org/professionals/physician-gls/PDF/nhl.pdf Accessed January 13, 2009.
  • 6
    • 0036682214 scopus 로고    scopus 로고
    • Treatment with ibritumomab tiuxetan radioimmunotherapy in patients with rituximab-refractory follicular non-Hodgkin's lymphoma
    • Witzig TE, Flinn IW, Gordon LI, et al. Treatment with ibritumomab tiuxetan radioimmunotherapy in patients with rituximab-refractory follicular non-Hodgkin's lymphoma. J Clin Oncol. 2002;20:3262-3269.
    • (2002) J Clin Oncol , vol.20 , pp. 3262-3269
    • Witzig, T.E.1    Flinn, I.W.2    Gordon, L.I.3
  • 7
    • 14144249536 scopus 로고    scopus 로고
    • Efficacy and safety of tositumomab and iodine-131 tositumomab (Bexxar) in B-cell lymphoma, progressive after rituximab
    • Horning SJ, Younes A, Jain V, et al. Efficacy and safety of tositumomab and iodine-131 tositumomab (Bexxar) in B-cell lymphoma, progressive after rituximab. J Clin Oncol. 2005;23:712-719.
    • (2005) J Clin Oncol , vol.23 , pp. 712-719
    • Horning, S.J.1    Younes, A.2    Jain, V.3
  • 8
    • 33750958771 scopus 로고    scopus 로고
    • National Lympho-Care Study Investigators. Initial therapeutic strategy in follicular lymphoma (FL): An analysis from the National Lymphocare Study (NLCS) [abstract]
    • June 20, Abstract 7527
    • Friedberg JW, Huang J, Dillon H, et al. National Lympho-Care Study Investigators. Initial therapeutic strategy in follicular lymphoma (FL): an analysis from the National Lymphocare Study (NLCS) [abstract]. J Clin Oncol. 2006;18S(June 20 suppl):428. Abstract 7527.
    • (2006) J Clin Oncol , vol.18 S , Issue.SUPPL. , pp. 428
    • Friedberg, J.W.1    Huang, J.2    Dillon, H.3
  • 9
    • 40749085662 scopus 로고    scopus 로고
    • Bendamustine (Treanda) displays a distinct pattern of cytotoxicity and unique mechanistic features compared with other alkylating agents
    • Leoni LM, Bailey B, Reifert J, et al. Bendamustine (Treanda) displays a distinct pattern of cytotoxicity and unique mechanistic features compared with other alkylating agents. Clin Cancer Res. 2008;14:309-317.
    • (2008) Clin Cancer Res , vol.14 , pp. 309-317
    • Leoni, L.M.1    Bailey, B.2    Reifert, J.3
  • 10
    • 0030005440 scopus 로고    scopus 로고
    • Bendamustine hydrochloride activity against doxorubicin-resistant human breast carcinoma cell lines
    • Strumberg D, Harstrick A, Doll K, Hoffmann B, Seeber S. Bendamustine hydrochloride activity against doxorubicin-resistant human breast carcinoma cell lines. Anticancer Drugs. 1996;7:415-421.
    • (1996) Anticancer Drugs , vol.7 , pp. 415-421
    • Strumberg, D.1    Harstrick, A.2    Doll, K.3    Hoffmann, B.4    Seeber, S.5
  • 11
    • 0034773457 scopus 로고    scopus 로고
    • Efficacy and toxicity of bendamustine in patients with relapsed low-grade non-Hodgkin's lymphomas
    • Heider A, Niederle N. Efficacy and toxicity of bendamustine in patients with relapsed low-grade non-Hodgkin's lymphomas. Anticancer Drugs. 2001;12:725-729.
    • (2001) Anticancer Drugs , vol.12 , pp. 725-729
    • Heider, A.1    Niederle, N.2
  • 12
    • 0036449340 scopus 로고    scopus 로고
    • High rates of long-lasting remissions after 5-day bendamustine chemotherapy cycles in pre-treated low-grade non-Hodgkin's-lymphomas
    • Bremer K. High rates of long-lasting remissions after 5-day bendamustine chemotherapy cycles in pre-treated low-grade non-Hodgkin's-lymphomas. J Cancer Res Clin Oncol. 2002;128:603-609.
    • (2002) J Cancer Res Clin Oncol , vol.128 , pp. 603-609
    • Bremer, K.1
  • 13
    • 20644469242 scopus 로고    scopus 로고
    • Bendamustine plus rituximab is effective and has a favorable toxicity profile in the treatment of mantle cell and low-grade non-Hodgkin's lymphoma
    • Rummel MJ, Al-Batran SE, Kim SZ, et al. Bendamustine plus rituximab is effective and has a favorable toxicity profile in the treatment of mantle cell and low-grade non-Hodgkin's lymphoma. J Clin Oncol. 2005;23:3383-3389.
    • (2005) J Clin Oncol , vol.23 , pp. 3383-3389
    • Rummel, M.J.1    Al-Batran, S.E.2    Kim, S.Z.3
  • 14
    • 34447549127 scopus 로고    scopus 로고
    • High anti-lymphoma activity of bendamustine/mitoxantrone/rituximab in rituximab pretreated relapsed or refractory indolent lymphomas and mantle cell lymphomas. A multicenter phase II study of the German Low Grade Lymphoma Study Group (GLSG)
    • Weide R, Hess G, Koppler H, et al. High anti-lymphoma activity of bendamustine/mitoxantrone/rituximab in rituximab pretreated relapsed or refractory indolent lymphomas and mantle cell lymphomas. A multicenter phase II study of the German Low Grade Lymphoma Study Group (GLSG). Leuk Lymphoma. 2007;48:1299-1306.
    • (2007) Leuk Lymphoma , vol.48 , pp. 1299-1306
    • Weide, R.1    Hess, G.2    Koppler, H.3
  • 15
    • 33646986211 scopus 로고    scopus 로고
    • Bendamustine, vincristine and prednisone (BOP) versus cyclophosphamide, vincristine and prednisone (COP) in advanced indolent non-Hodgkin's lymphoma and mantle cell lymphoma: Results of a randomised phase III trial (OSHO £19)
    • Herold M, Schulze A, Niederwieser D, et al. Bendamustine, vincristine and prednisone (BOP) versus cyclophosphamide, vincristine and prednisone (COP) in advanced indolent non-Hodgkin's lymphoma and mantle cell lymphoma: results of a randomised phase III trial (OSHO £19). J Cancer Res Clin Oncol. 2006;132:105-112.
    • (2006) J Cancer Res Clin Oncol , vol.132 , pp. 105-112
    • Herold, M.1    Schulze, A.2    Niederwieser, D.3
  • 16
    • 3442880514 scopus 로고    scopus 로고
    • Fludarabine and bendamustine in refractory and relapsed indolent lymphoma - a multicenter phase I/II trial of the East German Society of Hematology and Oncology (OSHO)
    • Koenigsmann M, Knauf W, Herold M, et al. Fludarabine and bendamustine in refractory and relapsed indolent lymphoma - a multicenter phase I/II trial of the East German Society of Hematology and Oncology (OSHO). Leuk Lymphoma. 2004;45:1821-1827.
    • (2004) Leuk Lymphoma , vol.45 , pp. 1821-1827
    • Koenigsmann, M.1    Knauf, W.2    Herold, M.3
  • 17
    • 38349119981 scopus 로고    scopus 로고
    • Bendamustine in patients with rituximab-refractory indolent and transformed non-Hodgkin's lymphoma: Results from a phase II multicenter, single-agent study
    • Friedberg JW, Cohen P, Chen L, et al. Bendamustine in patients with rituximab-refractory indolent and transformed non-Hodgkin's lymphoma: results from a phase II multicenter, single-agent study. J Clin Oncol. 2008;26:204-210.
    • (2008) J Clin Oncol , vol.26 , pp. 204-210
    • Friedberg, J.W.1    Cohen, P.2    Chen, L.3
  • 18
    • 0042449063 scopus 로고    scopus 로고
    • Report of an international workshop to standardize response criteria for non-Hodgkin's lymphomas. NCI Sponsored International Working Group
    • Cheson BD, Horning SJ, Coiffier B, et al. Report of an international workshop to standardize response criteria for non-Hodgkin's lymphomas. NCI Sponsored International Working Group. J Clin Oncol. 1999;17:1244-1244.
    • (1999) J Clin Oncol , vol.17 , pp. 1244-1244
    • Cheson, B.D.1    Horning, S.J.2    Coiffier, B.3
  • 19
    • 74549148613 scopus 로고    scopus 로고
    • National Cancer Institute. Common Terminology Criteria for Adverse Events, version 3.0 CTCAE, Published August 9, 2006. Available at:, pdf Accessed January 13, 2009
    • National Cancer Institute. Common Terminology Criteria for Adverse Events, version 3.0 (CTCAE). Published August 9, 2006. Available at: http://ctep.cancer.gov/protocolDevelopment/electronic-applications/docs/ctcaev3. pdf Accessed January 13, 2009.
  • 20
    • 33845382806 scopus 로고
    • Nonparametric estimation from incomplete observation
    • Kaplan EL, Meier P. Nonparametric estimation from incomplete observation. J Am Stat Assoc. 1958;53:457-481.
    • (1958) J Am Stat Assoc , vol.53 , pp. 457-481
    • Kaplan, E.L.1    Meier, P.2
  • 21
    • 40949136882 scopus 로고    scopus 로고
    • Acquirement of rituximab resistance in lymphoma cell lines is associated with both global CD20 gene and protein down-regulation regulated at the pretranscriptional and posttranscriptional levels
    • Czuczman MS, Olejniczak S, Gowda A, et al. Acquirement of rituximab resistance in lymphoma cell lines is associated with both global CD20 gene and protein down-regulation regulated at the pretranscriptional and posttranscriptional levels. Clin Cancer Res. 2008;14:1561-1570.
    • (2008) Clin Cancer Res , vol.14 , pp. 1561-1570
    • Czuczman, M.S.1    Olejniczak, S.2    Gowda, A.3
  • 22
    • 40949083386 scopus 로고    scopus 로고
    • Acquired resistance to rituximab is associated with chemotherapy resistance resulting from decreased Bax and Bak expression
    • Olejniczak SH, Hernandez-Ilizaliturri FJ, Clements JL, Czuczman MS. Acquired resistance to rituximab is associated with chemotherapy resistance resulting from decreased Bax and Bak expression. Clin Cancer Res. 2008;14:1550-1560.
    • (2008) Clin Cancer Res , vol.14 , pp. 1550-1560
    • Olejniczak, S.H.1    Hernandez-Ilizaliturri, F.J.2    Clements, J.L.3    Czuczman, M.S.4
  • 23
    • 35348940718 scopus 로고    scopus 로고
    • Viral infections in patients with hematological malignancies
    • Wade JC. Viral infections in patients with hematological malignancies. Hematology Am Soc Hematol Educ Program. 2006:368-374.
    • (2006) Hematology Am Soc Hematol Educ Program , pp. 368-374
    • Wade, J.C.1
  • 24
    • 20444411092 scopus 로고    scopus 로고
    • Assessment of treatment-related myelodysplastic syndromes and acute myeloid leukemia in patients with non-Hodgkin lymphoma treated with tositumomab and iodine I131 tositumomab
    • Bennett JM, Kaminski MS, Leonard JP, et al. Assessment of treatment-related myelodysplastic syndromes and acute myeloid leukemia in patients with non-Hodgkin lymphoma treated with tositumomab and iodine I131 tositumomab. Blood. 2005;105:4576-4582.
    • (2005) Blood , vol.105 , pp. 4576-4582
    • Bennett, J.M.1    Kaminski, M.S.2    Leonard, J.P.3
  • 26
    • 20444423607 scopus 로고    scopus 로고
    • Myelodysplasia and acute myeloid leukemia following therapy for indolent lymphoma with fludarabine, mitoxantrone, and dexamethasone (FND) plus rituximab and interferon alpha
    • McLaughlin P, Estey E, Glassman A, et al. Myelodysplasia and acute myeloid leukemia following therapy for indolent lymphoma with fludarabine, mitoxantrone, and dexamethasone (FND) plus rituximab and interferon alpha. Blood. 2005;105:4573-4575.
    • (2005) Blood , vol.105 , pp. 4573-4575
    • McLaughlin, P.1    Estey, E.2    Glassman, A.3
  • 27
    • 34948845600 scopus 로고    scopus 로고
    • Treatment-related myelodysplastic syndrome and acute myelogenous leukemia in patients treated with ibritumomab tiuxetan radioimmunotherapy
    • Czuczman MS, Emmanouilides C, Darif M, et al. Treatment-related myelodysplastic syndrome and acute myelogenous leukemia in patients treated with ibritumomab tiuxetan radioimmunotherapy. J Clin Oncol. 2007;25:4285-4292.
    • (2007) J Clin Oncol , vol.25 , pp. 4285-4292
    • Czuczman, M.S.1    Emmanouilides, C.2    Darif, M.3
  • 28
    • 52649177173 scopus 로고    scopus 로고
    • Phase II multicenter study of bendamustine plus rituximab in patients with relapsed indolent B-cell and mantle cell non-Hodgkin's lymphoma
    • Robinson KS, Williams ME, van der Jagt RH, et al. Phase II multicenter study of bendamustine plus rituximab in patients with relapsed indolent B-cell and mantle cell non-Hodgkin's lymphoma. J Clin Oncol. 2008;26:4473-4479.
    • (2008) J Clin Oncol , vol.26 , pp. 4473-4479
    • Robinson, K.S.1    Williams, M.E.2    van der Jagt, R.H.3
  • 29
    • 66349111607 scopus 로고    scopus 로고
    • Bendamustine plus rituximab versus CHOP plus rituximab in the first-line treatment of patients with follicular, indolent and mantle cell lymphomas. Results of a randomized phase III study of the Study Group Indolent Lymphomas (StiL) [abstract]
    • Abstract 2596
    • Rummel MJ, von Gruenhagen U, Niederle N, et al. Bendamustine plus rituximab versus CHOP plus rituximab in the first-line treatment of patients with follicular, indolent and mantle cell lymphomas. Results of a randomized phase III study of the Study Group Indolent Lymphomas (StiL) [abstract]. Blood (ASH Annual Meeting Abstracts). 2008;112:900. Abstract 2596.
    • (2008) Blood (ASH Annual Meeting Abstracts) , vol.112 , pp. 900
    • Rummel, M.J.1    von Gruenhagen, U.2    Niederle, N.3


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