Protein kinase a-Dependent biophysical phenotype for V227F-KCNJ2 mutation in catecholaminergic polymorphic ventricular tachycardia

Circulation: Arrhythmia and Electrophysiology

Volumn 2, Issue 5, 2009, Pages 540-547

  Makielski, Jonathan C ^b   Vega, Amanda L ^a,d   Tester, David J ^c   Ackerman, Michael J ^c  

^a University of Wisconsin Health   (United States)

^b Departments of Medicine (Cardiovascular Medicine) and Physiology   (United States)

^c MAYO CLINIC   (United States)

^d UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Andersen Tawil syndrome; Arrhythmia (mechanisms); K channel; Long QT syndrome

Indexed keywords

CATECHOLAMINE; CYCLIC AMP DEPENDENT PROTEIN KINASE; FORSKOLIN; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR2.1; ISOBUTYLMETHYLXANTHINE; SERINE;

ANDERSEN SYNDROME; ARTICLE; CATECHOLAMINERGIC POLYMORPHIC VENTRICULAR TACHYCARDIA; CELL STRAIN COS1; CONTROLLED STUDY; ENZYME ACTIVITY; GENE; GENE EXPRESSION; GENE MUTATION; HEART ARRHYTHMIA; HUMAN; HUMAN CELL; KCNJ2 GENE; MISSENSE MUTATION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; VOLTAGE CLAMP; WILD TYPE;

ADULT; ANALYSIS OF VARIANCE; ANDERSEN SYNDROME; ANIMALS; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; COS CELLS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DNA MUTATIONAL ANALYSIS; ELECTROCARDIOGRAPHY; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MUTATION, MISSENSE; PHENOTYPE; POTASSIUM CHANNELS, INWARDLY RECTIFYING; TACHYCARDIA, VENTRICULAR; TRANSFECTION;

EID: 74549219461     PISSN: 19413149     EISSN: 19413084     Source Type: Journal    
DOI: 10.1161/CIRCEP.109.872309     Document Type: Article

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