Application of the margin-of-exposure (MoE) approach to substances in food that are genotoxic and carcinogenic e.g.: Benzo[a]pyrene and polycyclic aromatic hydrocarbons

Food and Chemical Toxicology

Volumn 48, Issue SUPPL. 1, 2010, Pages

  Benford, Diane ^a   DiNovi, Michael ^b   Setzer, R Woodrow ^c  

^a FOOD STANDARDS AGENCY   (United Kingdom)

^b CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^c U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

BaP; Benzo a pyrene; Margin of exposure; MoE; PAHs; Polycyclic aromatic hydrocarbons

Indexed keywords

ANTHRACENE; BENZO[A]PYRENE; CHRYSENE; COAL TAR; FLUORENE; PERYLENE; PHENANTHRENE; POLYCYCLIC AROMATIC HYDROCARBON; PYRENE;

ARTICLE; CARCINOGENESIS; CARCINOGENICITY; DIETARY INTAKE; DOSE RESPONSE; FOOD CONTAMINATION; GENOTOXICITY; HISTIOCYTIC SARCOMA; HUMAN; INCIDENCE; JEJUNUM CANCER; KIDNEY ADENOMA; LARYNX PAPILLOMATOSIS; LIVER CELL CARCINOMA; LUNG ALVEOLUS CELL CARCINOMA; MOUTH CANCER; MUTAGENESIS; NONHUMAN; OCCUPATIONAL EXPOSURE; PAPILLOMA; RISK ASSESSMENT; TONGUE CARCINOMA;

ANIMALS; BENZO(A)PYRENE; CARCINOGENS; DATA INTERPRETATION, STATISTICAL; DIET; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FOOD CONTAMINATION; HUMANS; MALE; MICE; MODELS, STATISTICAL; MUTAGENS; NEOPLASMS; POLYCYCLIC HYDROCARBONS, AROMATIC; RATS;

MUS; RODENTIA;

EID: 74549196554     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2009.09.039     Document Type: Article

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