An inhibitor of protein arginine methyltransferases, 7,7′- carbonylbis(azanediyl)bis4-hydroxynaphthalene-2-sulfonic acid (AMI-1), is a potent scavenger of NADPH-oxidase-derived superoxide

Molecular Pharmacology

Volumn 77, Issue 2, 2010, Pages 280-287

  Chen, Feng ^a,b   Fulton, David J R ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

7,7' CARBONYLBIS(AZANEDIYL)BIS(4 HYDROXYNAPHTHALENE 2 SULFONIC ACID); ANTIOXIDANT; CALCIUM ION; HYDROGEN PEROXIDE; METHYLTRANSFERASE INHIBITOR; NITRIC OXIDE; PROTEIN ARGININE METHYLTRANSFERASE; PROTEIN ARGININE METHYLTRANSFERASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 5; SCAVENGER; SULFONIC ACID DERIVATIVE; SUPEROXIDE; TEMPOL; TIRON; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CATALYSIS; CONTROLLED STUDY; DRUG ACTIVITY; DRUG MECHANISM; DRUG POTENCY; DRUG SELECTIVITY; ENZYME ACTIVITY; ENZYME REGULATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN METHYLATION;

ANIMALS; ANTIOXIDANTS; CERCOPITHECUS AETHIOPS; COS CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; FREE RADICAL SCAVENGERS; NADPH OXIDASE; NAPHTHALENESULFONATES; PROTEIN-ARGININE N-METHYLTRANSFERASES; SUPEROXIDES; UREA;

EID: 74549155206     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.109.061077     Document Type: Article

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