Nanobubbles from gas-generating polymeric nanoparticles: Ultrasound imaging of living subjects

Angewandte Chemie - International Edition

Volumn 49, Issue 3, 2010, Pages 524-528

  Kang, Eunah ^a   Min, Hyun Su ^a   Lee, Jaeyoung ^b   Han, Moon Hee ^b   Ahn, Hyung Jun ^a   Yoon, In Chan ^a   Choi, Kuiwon ^a   Kim, Kwangmeyoung ^a   Park, Kinam ^c   Kwon, Ick Chan ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b Seoul National University Hospital   (South Korea)

^c PURDUE UNIVERSITY   (United States)

Author keywords

Carbon dioxide; Imaging agents; Nanostructures; Polymers; Ultrasound

Indexed keywords

HYDROPHOBICALLY MODIFIED CHITOSAN; IMAGING AGENT; IMAGING AGENTS; MICROBUBBLES; NANOBUBBLES; POLYMERIC NANOPARTICLES; SIDE CHAINS; ULTRASOUND IMAGING;

ACOUSTIC WAVES; CARBON DIOXIDE; COALESCENCE; NANOPARTICLES; ULTRASONICS;

BIODEGRADABLE POLYMERS;

CONTRAST MEDIUM; NANOPARTICLE; POLYMER;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; CHEMICAL STRUCTURE; CHEMISTRY; CLASSIFICATION; ECHOGRAPHY; GAS; MOUSE; NEOPLASM; PARTICLE SIZE; POROSITY; SUBCUTANEOUS DRUG ADMINISTRATION; SURFACE PROPERTY;

ANIMALS; CONTRAST MEDIA; GASES; INFUSIONS, SUBCUTANEOUS; MICE; MICE, INBRED BALB C; MOLECULAR STRUCTURE; NANOPARTICLES; NEOPLASMS; PARTICLE SIZE; POLYMERS; POROSITY; SURFACE PROPERTIES;

EID: 74549145150     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.200903841     Document Type: Article

References (19)

1. S. P. Qin, C. F. Caskey, K. W. Ferrara, Phys. Med. Biol. 2009, 54, R27-R57.
2. K. Ferrara, R. Pollard, M. Borden, Annu. Rev. Biomed. Eng. 2007, 9, 415-447.
3. E. G. Schutt, D. H. Klein, R. M. Mattrey, J. G. Riess, Angew. Chem. 2003, 115, 3336-3355;
4. Angew. Chem. Int. Ed. 2003, 42, 3218-3235.
5. J. R. Lindner, Nat. Rev. Drug Discovery 2004, 3, 527-532.
6. G. S. Kwon, M. Naito, M. Yokoyama, T. Okano, Y. Sakurai, K. Kataoka, Pharm. Res. 1995, 12, 192-195.
7. Y. Takakura, R. I. Mahato, M. Hashida, Adv. Drug Delivery Rev. 1998, 34, 93-108.
8. S. Keren, C. Zavaleta, Z. Cheng, A. de La Gheysens, S. S. Gambhir, Proc. Natl. Acad. Sci. USA 2008, 105, 5844-5849.
9. G. E. Weller, M. K. Wong, R. A. Modzelewski, E . Lu, A. L. Klibanov, W. R. Wagner, F. S. Villanueva, Cancer Res. 2005, 65, 533-539.
10. R. Weissleder, C. H. Tung, U Mahmood, A. Jr Bogdanov, Nat. Biotechnol. 1999, 17, 375-378.
11. K. H. Song, C. Kim, C. M. Cobley, Y. Xia, L. V. Wang, Nano Lett. 2009, 9, 183-188.
12. X. Wang, Y. Pang, G. Ku, X. Xie, G. Stoica, L. V. Wang, Nat. Biotechnol. 2003, 21, 803-806.
13. F. S. Villanueva, W. R. Wagner, Nat. Clin. Pract. Cardiovasc. Med. 2008, 5 Suppl 2, S26-32.
14. N. Rapoport, Z. G. Gao, A. Kennedy, J. Natl. Cancer Inst. 2007, 99, 1095-1106.
15. S. Agarwal, X. Xie, Macromolecules 2003, 36, 3545-3549.
16. M. Nishiura, Z. Hou, T. A. Koizumi, T. Imamoto, Y. Wakatsuki, Macromolecules 1999, 32, 8245-8251.
17. K. Park, J. H. Kim, Y. S. Nam, S. Lee, H. Y. Nam, K. Kim, J. H. Park, I. S. Kim, K. Choi, S. Y. Kim, I. C. Kwon, J. Controlled Release 2007, 122, 305-314.
18. S. Rossi, G. Waton, M. P. Krafft, ChemPhysChem 2008, 9, 1982-1985.
19. F. Gerber, M. P. Krafft, G. Waton, T. F. Vandamme, New J. Chem. 2006, 30, 524-527.