Unmyelinated aplysia nerves exhibit a nonmonotonic blocking response to high-frequency stimulation

IEEE Transactions on Neural Systems and Rehabilitation Engineering

Volumn 17, Issue 6, 2009, Pages 537-544

  Joseph, Laveeta ^a   Butera, Robert J ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Action potential; Extracellular recording; Peripheral nerves; Suction electrode

Indexed keywords

ACTION POTENTIALS; ALTERNATING CURRENT; APLYSIA; APLYSIA CALIFORNICA; BLOCK CONDUCTION; CABLE MODEL; COMPUTATIONAL STUDIES; EXTRACELLULAR RECORDING; HIGH FREQUENCY HF; MYELINATED NERVES; NONMONOTONIC; PERIPHERAL NERVES; SINUSOIDAL WAVEFORMS; WAVE FORMS;

ABERRATIONS;

EXPERIMENTS;

ACTION POTENTIAL; ANIMAL; APLYSIA; ARTICLE; ELECTROSTIMULATION; METHODOLOGY; NERVE BLOCK; NERVE CELL INHIBITION; NERVE CONDUCTION; NONMYELINATED NERVE; PHYSIOLOGY;

ACTION POTENTIALS; ANIMALS; APLYSIA; ELECTRIC STIMULATION; NERVE BLOCK; NERVE FIBERS, UNMYELINATED; NEURAL CONDUCTION; NEURAL INHIBITION;

EID: 74549137953     PISSN: 15344320     EISSN: None     Source Type: Journal    
DOI: 10.1109/TNSRE.2009.2029490     Document Type: Article

References (43)

1. P. L. Perot and S. N. Stein, "Conduction block in peripheral nerve produced by oxygen at high pressure," Science, vol.123, pp. 802-803, 1956.
2. P. L. Perot and S. N. Stein, "Conduction block in mammalian nerve produced by O-2 at high pressure," Amer. J. Physiol., vol.197, pp. 1243-1246, 1959.
3. D. N. Franz and A. Iggo, "Conduction failure in myelinated and nonmyelinated axons at low temperatures," J. Physiol.-London, vol.199, p. 319, 1968.
4. S. McMullan, D. A. A. Simpson, and B. M. Lumb, "A reliable method for the preferential activation of C- or A-fibre heat nociceptors," J. Neurosci. Methods, vol.138, pp. 133-139, 2004.
5. V. N. Martinov and A. Nja, "A microcapsule technique for long-term conduction block of the sciatic nerve by tetrodotoxin," J. Neurosci. Methods, vol.141, pp. 199-205, 2005.
6. M. Guven, H. Bozdemir, I. Gunay, Y. Sarica, I. Kahraman, and F. Koc, "The actions of lamotrigine and levetiracetam on the conduction properties of isolated rat sciatic nerve," Eur. J. Pharmacol., vol.553, pp. 129-134, 2006.
7. M. Guven, K. Ozgunen, and I. Gunay, "Conduction blocks of lidocaine on crushed rat sciatic nerve: An in-vitro study," Int. J. Neurosci., vol.115, pp. 725-734, 2005.
8. G. Strichartz, "Molecular mechanisms of nerve block by local-anesthetics," Anesthesiology, vol.45, pp. 421-441, 1976.
9. L. Reboul and A. Rosenblueth, "The action of alternating currents upon the electrical excitability of nerve," Amer. J. Physiol., vol.125, pp. 205-215, 1939.
10. A. Rosenblueth and J. Reboul, "The blocking and deblocking effects of alternating currents on nerve," Amer. J. Physiol., vol.125, pp. 251-264, 1939.
11. J. A. Tanner, "Reversible blocking of nerve conduction by alternatingcurrent excitation," Nature, vol.195, pp. 712-713, 1962.
12. B. R. Bowman and D. R. McNeal, "Response of single alpha-motoneurons to high-frequency pulse trains-Firing behavior and conduction block phenomenon," Appl. Neurophysiol., vol.49, pp. 121-138, 1986.
13. K. L. Kilgore and N. Bhadra, "Nerve conduction block utilising highfrequency alternating current," Med. Biol. Eng. Comput., vol.42, pp. 394-406, 2004. (Pubitemid 38786703)
14. N. Bhadra and K. L. Kilgore, "Direct current electrical conduction block of peripheral nerve," IEEE Trans. Neural Syst. Rehabil. Eng., vol.12, no.3, pp. 313-324, Sep. 2004. (Pubitemid 39223612)
15. J. C. Petruska, C. H. Hubscher, and R. D. Johnson, "Anodally focused polarization of peripheral nerve allows discrimination of myelinated and unmyelinated fiber input to brainstem nuclei," Exp. Brain Res., vol.121, pp. 379-390, 1998.
16. S. M. ElBasiouny and V. K. Mushahwar, "Modulation of motoneuronal firing behavior after spinal cord injury using intraspinal microstimulation current pulses: A modeling study," J. Appl. Physiol., vol.103, pp. 276-286, 2007.
17. B. Campbell and M. Y.Woo, "Asynchronous firing + block of peripheral nerve conduction by 20 kc alternating currents," Federation Proc., vol.23, pp. 112-&, 1964.
18. N. Bhadra and K. L. Kilgore, "High-frequency electrical conduction block of mammalian peripheral motor nerve," Muscle Nerve, vol.32, pp. 782-790, 2005. (Pubitemid 41746267)
19. N. Bhadra, N. Bhadra, K. Kilgore, and K. J. Gustafson, "High frequency electrical conduction block of the pudendal nerve," J. Neural Eng., vol.3, pp. 180-186, 2006.
20. M. Ishigooka, T. Hashimoto, I. Sasagawa, K. Izumiya, and T. Nakada, "Modulation of the urethral pressure by high-frequency block stimulus in dogs," Eur. Urol., vol.25, pp. 334-337, 1994.
21. C. F. Tai, J. R. Roppolo, and W. C. D. Groat, "Response of external urethral sphincter to high frequency biphasic electrical stimulation of pudendal nerve," J. Urol., vol.174, pp. 782-786, 2005.
22. C. F. Tai, S. E. Smerin, W. C. de Groat, and J. R. Roppolo, "Pudendal- to-bladder reflex in chronic spinal-cord-injured cats," Exp. Neurol., vol.197, pp. 225-234, 2006.
23. R. P. Williamson and B. J. Andrews, "Localized electrical nerve blocking," IEEE Trans. Biomed. Eng., vol.52, no.3, pp. 362-370, Mar.2005.
24. N. Bhadra, E. A. Lahowetz, S. T. Foldes, and K. L. Kilgore, "Simulation of high-frequency sinusoidal electrical block of mammalian myelinated axons," J. Computat. Neurosci., vol.22, pp. 313-326, 2007.
25. C. F. Tai, W. C. de Groat, and J. R. Roppolo, "Simulation of nerve block by high-frequency sinusoidal electrical current based on the Hodgkin-Huxley model," IEEE Trans. Neural Syst. Rehabil. Eng., vol.13, no.3, pp. 415-422, Sep. 2005.
26. C. F. Tai, W. C. de Groat, and J. R. Roppolo, "Simulation analysis of conduction block in unmyelinated axons induced by high-frequency biphasic electrical currents," IEEE Trans. Biomed. Eng., vol.52, no.7, pp. 1323-1332, Jul. 2005.
27. X. Zhang, J. R. Roppolo, W. C. de Groat, and C. F. Tai, "Mechanism of nerve conduction block induced by high-frequency biphasic electrical currents," IEEE Trans. Biomed. Eng., vol.53, no.12, pp. 2445-2454, Dec. 2006.
28. X. Zhang, J. R. Roppolo, W. C. de Groat, and C. F. Tai, "Simulation analysis of conduction block in myelinated axons induced by high-frequency biphasic rectangular pulses," IEEE Trans. Biomed. Eng., vol.53, no.7, pp. 1433-1436, Jul. 2006.
29. M. Solomonow, E. Eldred, J. Lyman, and J. Foster, "Control of muscle contractile-force through indirect high-frequency stimulation," Amer. J. Phys. Med. Rehabil., vol.62, pp. 71-82, 1983.
30. E. R. Kandel, Behavioral Biology of Aplysia: A Contribution to the Comparative Study of Opisthobranch Molluscs. San Francisco, CA: W. H. Freeman, 1979.
31. E. R. Kandel, J. H. Schwartz, and T. M. Jessell, Principles of Neural Science, 4th ed. New York: McGraw-Hill, 2000.
32. L. Joseph and R. J. Butera, "Conduction block in unmyelinated nerves using high frequency AC stimulation," in Proc. 3rd Int. IEEE/EMBS Conf. Neural Eng., Kohala Coast, HI, 2007, pp. 575-577.
33. L. Joseph, B. D. Haeffele, and R. J. Butera, "Conduction block induced by high frequency AC stimulation in unmyelinated nerves," in Proc. 29th Annu. Int. Conf. IEEE EMBS, Lyon, France, 2007, pp. 1719-1722.
34. T. Nowotny, V. P. Zhigulin, A. I. Selverston, H. D. I. Abarbanel, and M. I. Rabinovich, "Enhancement of synchronization in a hybrid neural circuit by spike-timing dependent plasticity," J. Neurosci., vol.23, pp. 9776-9785, 2003.
35. J. D. Miles, K. L. Kilgore, N. Bhadra, and E. A. Lahowetz, "Effects of ramped amplitude waveforms on the onset response of high-frequency mammalian nerve block," J. Neural Eng., vol.4, pp. 390-398, 2007.
36. D. A. Haydon and B. W. Urban, "The admittance of the squid giantaxon at radio frequencies and its relation to membrane-structure," J. Physiol.-London, vol.360, pp. 275-291, 1985.
37. B. D. Haeffele and R. J. Butera, "Modifying the Hodgkin-Huxley model for high frequency AC stimulation," in Proc. 3rd Int. IEEE/EMBS Conf. Neural Eng., Kohala Coast, HI, 2007, pp. 550-552.
38. A. L. Jensen and J. M. Durand, "Suppression of axonal conduction by sinusoidal stimulation in rat hippocampus in vitro," J. Neural Eng., vol.4, pp. 1-16, 2007.
39. D. M. Durand and M. Bikson, "Suppression and control of epileptiform activity by electrical stimulation: A review," Proc. IEEE, vol.89, no.7, pp. 1065-1082, Jul. 2001.
40. D. O. Smith, "Axon conduction failure under in vivo conditions in crayfish," J. Physiol., vol.344, pp. 327-333, 1983.
41. Y. Grossman, I. Parnas, and M. E. Spira, "Differential conduction block in branches of a bifurcating axon," J. Physiol., vol.295, pp. 283-305, 1979.
42. Y. Grossman, I. Parnas, and M. E. Spira, "Ionic mechanisms involved in differential conduction of action potentials at high-frequency in a branching axon," J. Physiol.-London, vol.295, pp. 307-&, 1979.
43. M. Solomonow, "External control of the neuromuscular system," IEEE Trans. Biomed. Eng., vol.31, no.12, pp. 752-763, Dec. 1984.