-
1
-
-
74549205743
-
A CYP3A4 phenotype-based dosing algorithm for individualized treatment of irinotecan
-
van der Bol JM, Mathijssen RHJ, Creemers GM. A CYP3A4 phenotype-based dosing algorithm for individualized treatment of irinotecan. Clin Cancer Res 2010;16:736-42.
-
(2010)
Clin Cancer Res
, Issue.16
, pp. 736-742
-
-
van der Bol, J.M.1
Mathijssen, R.H.J.2
Creemers, G.M.3
-
2
-
-
0034038190
-
Pharmacokinetics, metabolism, and excretion of irinotecan (CPT-11) following I.V. infusion of [(14)C] CPT-11 in cancer patients
-
Slatter JG, Schaaf LJ, Sams JP, et al. Pharmacokinetics, metabolism, and excretion of irinotecan (CPT-11) following I.V. infusion of [(14)C] CPT-11 in cancer patients. Drug Metab Dispos 2000;28:423-33.
-
(2000)
Drug Metab Dispos
, vol.28
, pp. 423-433
-
-
Slatter, J.G.1
Schaaf, L.J.2
Sams, J.P.3
-
3
-
-
61349108073
-
Phase II trial of two different irinotecan schedules with pharmacokinetic analysis in patients with recurrent glioma: North Central Cancer Treatment Group results
-
Santisteban M, Buckner JC, Reid JM, et al. Phase II trial of two different irinotecan schedules with pharmacokinetic analysis in patients with recurrent glioma: North Central Cancer Treatment Group results. J Neurooncol 2009;92:165-75.
-
(2009)
J Neurooncol
, vol.92
, pp. 165-175
-
-
Santisteban, M.1
Buckner, J.C.2
Reid, J.M.3
-
5
-
-
2342459714
-
Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan
-
Innocenti F, Undevia SD, Iyer L, et al. Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan. J Clin Oncol 2004;22:1382-8.
-
(2004)
J Clin Oncol
, vol.22
, pp. 1382-1388
-
-
Innocenti, F.1
Undevia, S.D.2
Iyer, L.3
-
6
-
-
0035057872
-
Pharmacogenetics of anticancer agents: Lessons from amonafide and irinotecan
-
Innocenti F, Iyer L, Ratain MJ. Pharmacogenetics of anticancer agents: lessons from amonafide and irinotecan. Drug Metab Dispos 2001;29:596-600.
-
(2001)
Drug Metab Dispos
, vol.29
, pp. 596-600
-
-
Innocenti, F.1
Iyer, L.2
Ratain, M.J.3
-
7
-
-
0142157104
-
Carboxylesterases expressed in human colon tumor tissue and their role in CPT-11 hydrolysis
-
Sanghani SP, Quinney SK, Fredenburg TB, et al. Carboxylesterases expressed in human colon tumor tissue and their role in CPT-11 hydrolysis. Clin Cancer Res 2003;9:4983-91.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 4983-4991
-
-
Sanghani, S.P.1
Quinney, S.K.2
Fredenburg, T.B.3
-
8
-
-
3042677708
-
Flat-fixed dosing of irinotecan: Influence on pharmacokinetic and pharmacodynamic variability
-
de Jong FA, Mathijssen RH, Xie R, Verweij J, Sparreboom A. Flat-fixed dosing of irinotecan: influence on pharmacokinetic and pharmacodynamic variability. Clin Cancer Res 2004;10:4068-71.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 4068-4071
-
-
de Jong, F.A.1
Mathijssen, R.H.2
Xie, R.3
Verweij, J.4
Sparreboom, A.5
-
9
-
-
74549152842
-
A genotype-driven phase I study of irinotecan administered in combination with 5-fluorouracil/leucovorin (FOLFIRI) in metastatic colorectal cancer patients
-
In press
-
Toffoli G, Cecchin E, Gasparaini G, et al. A genotype-driven phase I study of irinotecan administered in combination with 5-fluorouracil/leucovorin (FOLFIRI) in metastatic colorectal cancer patients. J Clin Oncol. In press 2009.
-
(2009)
J Clin Oncol
-
-
Toffoli, G.1
Cecchin, E.2
Gasparaini, G.3
-
10
-
-
66849111193
-
Comprehensive pharmacogenetic analysis of irinotecan neutropenia and pharmacokinetics
-
Innocenti F, Kroetz DL, Schuetz E, et al. Comprehensive pharmacogenetic analysis of irinotecan neutropenia and pharmacokinetics. J Clin Oncol 2009;27:2604-14.
-
(2009)
J Clin Oncol
, vol.27
, pp. 2604-2614
-
-
Innocenti, F.1
Kroetz, D.L.2
Schuetz, E.3
-
11
-
-
0025744506
-
Pharmacologically based dosing of etoposide: A means of safely increasing dose intensity
-
Ratain MJ, Mick R, Schilsky RL, Vogelzang NJ, Berezin F. Pharmacologically based dosing of etoposide: a means of safely increasing dose intensity. J Clin Oncol 1991;9:1480-6.
-
(1991)
J Clin Oncol
, vol.9
, pp. 1480-1486
-
-
Ratain, M.J.1
Mick, R.2
Schilsky, R.L.3
Vogelzang, N.J.4
Berezin, F.5
-
12
-
-
33847666051
-
Personalized medicine: Building the GPS to take us there
-
Ratain MJ. Personalized medicine: building the GPS to take us there. Clin Pharmacol Ther 2007;81:321-2.
-
(2007)
Clin Pharmacol Ther
, vol.81
, pp. 321-322
-
-
Ratain, M.J.1
|