In vivo antitussive activity of Coccinia grandis against irritant aerosol and sulfur dioxide-induced cough model in rodents

Bangladesh Journal of Pharmacology

Volumn 4, Issue 2, 2009, Pages 84-87

  Pattanayak, Shakti Prasad ^a   Sunita, Priyashree ^b  

^a BIRLA INSTITUTE OF TECHNOLOGY   (India)

^b Government Pharmacy Institute   (India)

Author keywords

Aerosol; Antitussive; Coccinia grandis; Cough

Indexed keywords

ANTITUSSIVE AGENT; CITRIC ACID; COCCINIA GRANDIS EXTRACT; CODEINE; CODEINE PHOSPHATE; METHANOL; PLANT EXTRACT; SULFUR DIOXIDE; UNCLASSIFIED DRUG;

AEROSOL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; COUGHING; CUCUMBER; DISEASE MODEL; DOSE RESPONSE; DRUG ACTIVITY; DRUG EFFICACY; EXPERIMENTAL GUINEA PIG; MALE; MOUSE; NONHUMAN;

EID: 74549118268     PISSN: 1991007X     EISSN: None     Source Type: Journal    
DOI: 10.3329/bjp.v4i2.1537     Document Type: Article

References (15)

1. Cavanagh RL, Gylys JA, Bierwagen ME. Antitussive properties of butorphanol. Arch In Pharmacodyn. 1976; 220: 258-68.
2. Chopra RN, Nayar SL, Chopra IC. Glossary of Indian medicinal plants. New Delhi, Publication and Information Directorate, Council of Scientific and Industrial Research, 1956, p.77.
3. De Boer JKH, Anneleen K, Anders B, William M, Hedberg I, Levenfors JJ. Anti-fungal and anti-bacterial activity of some herbal remedies from Tanzania. J Ethnopharmacol. 2005; 96: 461-69. doi:10.1016/j.jep.2004.09.035 PMid:15619565
4. Forsberg K, Karlsson JA, Theodorsson E, Lundberg JM, Persson CGA. Cough and bronchconstriction mediated by capsaicin sensitive sensory neurons in guinea pigs. Pulmonary Pharmacol. 1988; 1: 33-39. doi:10.1016/0952-0600(88)90008-7 PMid:2980286
5. Karlsson JA, Lanner AS, Persson GA. Airway opioid receptors mediate inhibition of cough and reflax bronchoconstriction in guinea pigs. J Pharmacol Exp Ther. 1990; 252: 863-68.
6. Kumar GP, Sudheesh S, Vijayalakshmi NR. Hypoglycemic effect of Coccinia indica: Mechanism of action. Planta Med. 1993; 59: 330- 32. doi:10.1055/s-2006-959693 PMid:8372150
7. Miyagoshi M, Amagaya, S, Ogihara Y. Antitussive effects of lephedrine, amygdalin and makyokansokito (Chinese traditional medicine) using a cough model induced by sulfur dioxide gas in mice. Planta Med. 1986; 52: 275-78. doi:10.1055/s-2007-969151 PMid:17345306
8. Mukerjee K, Ghosh NC, Datta T. Coccinia indica, as potential hypoglycaemic agent. Indian J Exp Biol. 1972; 10: 347-49.
9. Pickering RW, James GWL. The antitussive activity of a novel compound RU 20201. Drug Res. 1979; 29: 287-89.
10. Singh G, Gupta P, Rawat P, Puri A, Bhatia G, Maurya R. Antidyslipidemic activity of polyprenol from Coccinia grandis in high-fat diet-fed hamster model. Phytomedicine 2007; 14: 792-98. doi: 10.1016/j.phymed.2007.06.008 PMid:17689941
11. Singh N, Singh SP, Vrat S, Misra N, Dixit KS, Kohli RP. A study on the antidiabetic activity of Coccinia indica in dogs. Indian J Med Sci. 1985; 39: 27-29.
12. Tedeschi RE, Tedeschi DH, Hitchens JT, Cook L, Mattis PA, Fellows EJ. A new antitussive method involving mechanical stimulation in unanesthetized dogs. J Pharmacol Exp Ther. 1959; 126: 338-44.
13. Turner RA. Screening methods in pharmacology. New York, Academic Press, 1968, p 128.
14. Umamaheswari M, Kuppusamy AK, Somasundaram A, Sivashanmugm T, Subhadradevi V, Thenvungal, KR. Xanthine oxidase inhibitory activity of some Indian medical plants. J Ethnopharmacol. 2007; 109: 547-51.doi:10.1016/j.jep. 2006.08.020 PMid:17014977
15. Varier PS, Sala AV. Indian medicinal plants: A compendium of 500 plants. New Delhi, Orient Longmann, 1994, p 133. PMid:17689941