Survival, Causes of Death, and Risk Factors Associated With Mortality in Spanish Systemic Sclerosis Patients: Results From a Single University Hospital

Seminars in Arthritis and Rheumatism

Volumn 39, Issue 4, 2010, Pages 285-293

  Joven, Beatriz E ^a   Almodovar, Raquel ^b   Carmona, Loreto ^c   Carreira, Patricia E ^a  

^a HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

^b HOSPITAL UNIVERSITARIO FUNDACIÓN ALCORCÓN   (Spain)

^c UNIDAD DE INVESTIGACIÓN   (Spain)

Author keywords

causes of death; diffuse scleroderma; mortality; risk factors for mortality; survival; systemic scleroderma; systemic sclerosis

Indexed keywords

ANTINUCLEAR ANTIBODY; AZATHIOPRINE; CARBON MONOXIDE; CARDIOLIPIN ANTIBODY; CHLOROQUINE; CYCLOPHOSPHAMIDE; PENICILLAMINE; PROSTAGLANDIN; SCL 70 ANTIBODY; STEROID;

ADULT; AGE; ARTICLE; CAUSAL ATTRIBUTION; CAUSE OF DEATH; COMORBIDITY; DIFFUSE SCLERODERMA; DIGITAL ULCER; ENCEPHALITIS; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; GASTROINTESTINAL DISEASE; HEART DISEASE; HUMAN; INFECTION; INTERSTITIAL LUNG DISEASE; KIDNEY DISEASE; LIMITED SCLERODERMA; LUNG DIFFUSION CAPACITY; LUNG FIBROSIS; LUPUS CEREBRITIS; MAJOR CLINICAL STUDY; MALE; MORTALITY; MYELITIS; NEOPLASM; PERIPHERAL VASCULAR DISEASE; PRIORITY JOURNAL; PROGNOSIS; PROTEINURIA; PULMONARY HYPERTENSION; RISK FACTOR; SEX DIFFERENCE; SKIN DEFECT; SKIN ULCER; SURVIVAL; SURVIVAL RATE; SURVIVAL TIME; SYSTEMIC SCLEROSIS; UNIVERSITY HOSPITAL;

EID: 74449087538     PISSN: 00490172     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.semarthrit.2009.06.002     Document Type: Article

References (40)

1. Barnett A.J., Miller M.H., and Littlejohn G. A survival study of patients with scleroderma diagnosed over 30 years (1953-1983): the value of a simple cutaneous classification in the early stages of the disease. J Rheumatol 15 (1988) 276-283
2. Altman R.D., Medsger T., Bloch D.A., and Michael B.A. Predictors of survival in systemic sclerosis (scleroderma). Arthritis Rheum 34 (1991) 403-413
3. Silman A. Mortality from scleroderma in England and Wales. Ann Rheum Dis 50 (1991) 95-96
4. Abu-Shakra M., and Lee P. Mortality in systemic sclerosis: a comparison with the general population. J Rheumatol 22 (1995) 2100-2102
5. Nishioka K., Katayama I., Kondo H., Shinkai H., Ueki H., Tamaki K., et al. Epidemiological analysis of prognosis of 496 Japanese patients with progressive systemic sclerosis. J Dermatol 23 (1996) 677-682
6. Czirják L., Pákozdi A., Kumánovics G., Varjú C., Szekanecz Z., Nagy Z., et al. Survival and causes of death in 366 Hungarian patients with systemic sclerosis. Ann Rheum Dis 67 (2008) 59-63
7. Simeón C.P., Armadans L., Fonollosa V., Solans R., Selva A., Villar M., et al. Mortality and prognostic factors in Spanish patients with systemic sclerosis. Rheumatology 42 (2003) 71-75
8. Jacobsen S., Halberg P., and Ullman S. Mortality and causes of death of 344 Danish patients with systemic sclerosis (scleroderma). Br J Rheumatol 37 (1998) 750-755
9. Hesselstrand R., Scheja A., and Akesson A. Mortality and causes of death in a Swedish series of systemic sclerosis patients. Ann Rheum Dis 57 (1998) 682-686
10. Bryan C., Knight C., Black C.M., and Silman A.J. Prediction of five-year survival following presentation with scleroderma. Arthritis Rheum 42 (1999) 2660-2665
11. Ferri C., Valentini G., Cozzi F., Sebatiani M., Michelassi C., La Montagna G., et al., Systemic Sclerosis Study Group of Italian Society of Rheumatology (SIR-GSSSc). Systemic sclerosis demographic, clinical, and serologic features and survival in 1,012 Italian patients. Medicine 81 (2002) 139-153
12. Scusell-Lonzetti L., Joyal F., Raynauld J.P., Roussin A., Rich E., Goulet J.R., et al. Predicting mortality in systemic sclerosis analysis of a cohort of 309 french Canadian patients with emphasis on features at diagnosis as predictive factors for survival. Medicine 81 (2002) 154-167
13. Mayes M.D., Lacey Jr. J.V., Beebe-Dimmer J., Gillespie B.W., Cooper B., Laing T.J., et al. Prevalence, incidence, survival, and diseases characteristics of systemic sclerosis in a large US population. Arthritis Rheum 48 (2003) 2246-2255
14. Alamamos Y., Tsifetaki N., Voulgari P.V., Siozos C., Tsamandouraki K., Alexiou G.A., et al. Epidemiology of systemic sclerosis in Northwest Greece 1981 to 2002. Semin Arthritis Rheum 34 (2005) 714-720
15. Ioannidis J.P., Vlachoyiannopoulos P.G., Haidich A.B., Medsger Jr. T.A., Lucas M., Michet C.J., et al. Mortality in systemic sclerosis: an international meta-analysis of individual patient data. Am J Med 118 (2005) 2-10
16. Mayes M.D. Scleroderma epidemiology. Rheum Dis North Am 29 (2003) 239-254
17. Subcommittee for scleroderma criteria of the American Rheumatism Association diagnostic and therapeutic criteria committee. Preliminary criteria for the classification of systemic sclerosis (scleroderma). Arthritis Rheum 23 (1980) 581-590
18. LeRoy E.C., and Medsger T.A. Criteria for the classification of early systemic sclerosis. J Rheumatol 28 (2001) 1573-1576
19. LeRoy E.C., Black C., Fleischmajer R., Jablonska S., Krieg T., Medsger Jr. T.A., et al. Scleroderma (systemic sclerosis): classification, subsets and pathogenesis. J Rheumatol 15 (1988) 202-205
20. Brennan P., Silman A., Black C., Bernstein R., Coppock J., Maddison P., et al., The UK Study Group. Reliability of skin involvement measures in scleroderma. Br J Rheumatol 31 (1992) 457-460
21. Instituto Nacional de Estadística. Demografía y población. Movimiento natural de la población. At: http://www.ine.es/inebase/cgi/.
22. Silman A. Demographics and survival. J Rheumatol 24 (1997) 58-62
23. Simeón C.P., Armadans L., Fonollosa V., Vilardell M., Candell J., Tolosa C., et al. Survival prognostic factors and markers of morbidity in Spanish patients with systemic sclerosis. Ann Rheum Dis 56 (1997) 723-728
24. Silman A. Scleroderma and survival. Ann Rheum Dis 50 (1991) 267-269
25. Stupi A.M., Steen V.D., Owens G.R., Barnes E.L., Rodnan G.P., and Medsger Jr. T.A. Pulmonary hypertension in the CREST syndrome variant of systemic sclerosis. Arthritis Rheum 29 (1986) 515-524
26. Coral-Alvarado P., Rojas-Villarraga A., Latorre M.C., Mantilla R.D., Restrepo J.F., Pardo A.L., et al. Risk factors associated with pulmonary arterial hypertension in Colombian patients with systemic sclerosis: review of the literature. J Rheumatol 35 (2008) 244-250
27. Walker U.A., Tyndall A., Czirják L., Denton C., Farge-Bancel D., Kowal-Bielecka O., et al. Clinical risk assessment of organ manifestations in systemic sclerosis: a report from the EULAR Sclerodema Trials and Research group database. Ann Rheum Dis 66 (2007) 754-763
28. Hunzelmann N., Genth E., Krieg T., Lehmacher W., Melchers I., Meurer M., et al. The registry of the German Network for Systemic Scleroderma: frequency of disease subsets and patterns of organ involvement. Rheumatology 47 (2008) 1185-1192
29. Trad S., Amoura Z., Beigelman C., Haroche J., Costedoat N., Boutin Le T.H., et al. Pulmonary arterial hypertension is a major mortality factor in diffuse systemic sclerosis, independent of interstitial lung disease. Arthritis Rheum 54 (2006) 184-191
30. Veale D.J., Collidge T.A., and Belch J.J.F. Increased prevalence of symptomatic macrovascular disease in systemic sclerosis. Ann Rheum Dis 54 (1995) 853-855
31. Stafford L., Englert H., Gover J., and Bertouch J. Distribution of macrovascular disease in scleroderma. Ann Rheum Dis 57 (1998) 476-479
32. Ho M., Veale D., Eastmond C., Nuki G., Belch J., and East of Scotland Systemic Sclerosis Study Group. Macrovascular diseases and systemic sclerosis. Ann Rheum Dis 59 (2000) 39-43
33. Taylor M.H., McFadden J.A., Bolster M.B., and Silver R.M. Ulnar artery involvement in systemic sclerosis (scleroderma). J Rheumatol 29 (2002) 102-106
34. Khurma V., Meyer C., Park G.S., McMahon M., Lin J., Singh R.R., et al. A pilot study of subclinical coronary atherosclerosis in systemic sclerosis: coronary artery calcification in cases and controls. Arthritis Rheum 59 (2008) 591-597
35. Kyndt X., Hebbar M., Queyrel V., Hachulla E., Hatron P.Y., and Devulder B. Systemic sclerosis and cancer. Search for predictive factors of cancer in 123 patients with scleroderma. Rev Med Interrne 18 (1997) 528-532
36. Chatterjee S., Dombi G.W., Severson R.K., and Mayes M.D. Risk of cancer in scleroderma: a population-based cohort study. Arthritis Rheum 52 (2005) 2415-2424
37. Ruiz-Ramos M., and Expósito-Hernández J. Tendencia de la mortalidad por cáncer en Andalucía entre 1975-2003. Med Clin 128 (2007) 448-452
38. Pollán M., Ramis R., Aragonés N., Pérez-Gómez B., Gómez D., Lope V., et al. Municipal distribution of breast cancer mortality among women in Spain. BMC Cancer 7 (2007) 78
39. Ferlay J., Bray F., Sankila R., and Parkin D.M. EUCAN: Cancer Incidence, Mortality and Prevalence in the European Union 1998, version 5.0. IARC CancerBase No. 4 (1999), IARC Press, Lyon
40. Ferlay J., Bray F., Pisani P., and Parkin D.M. GLOBOCAN: Cancer Incidence, Mortality and Prevalence in Worldwide, version 2.0. IARC CancerBase No. 5 (2004), IARC Press, Lyon