-
1
-
-
0016722749
-
Catalytic mechanism of carbonic-anhydrase - hydrogen-isotope effects on kinetic-parameters of human C isoenzyme
-
Steiner H., Jonsson B.H., and Lindskog S. Catalytic mechanism of carbonic-anhydrase - hydrogen-isotope effects on kinetic-parameters of human C isoenzyme. Eur. J. Biochem. 59 (1975) 253-259
-
(1975)
Eur. J. Biochem.
, vol.59
, pp. 253-259
-
-
Steiner, H.1
Jonsson, B.H.2
Lindskog, S.3
-
2
-
-
0024421430
-
Role of histidine 64 in the catalytic mechanism of human carbonic anhydrase II studied with a site-specific mutant
-
Tu C.K., Silverman D.N., Forsman C., Jonsson B.H., and Lindskog S. Role of histidine 64 in the catalytic mechanism of human carbonic anhydrase II studied with a site-specific mutant. Biochemistry 28 (1989) 7913-7918
-
(1989)
Biochemistry
, vol.28
, pp. 7913-7918
-
-
Tu, C.K.1
Silverman, D.N.2
Forsman, C.3
Jonsson, B.H.4
Lindskog, S.5
-
3
-
-
33845278732
-
The catalytic mechanism of carbonic-anhydrase - implications of a rate-limiting protolysis of water
-
Silverman D.N., and Lindskog S. The catalytic mechanism of carbonic-anhydrase - implications of a rate-limiting protolysis of water. Acc. Chem. Res. 21 (1988) 30-36
-
(1988)
Acc. Chem. Res.
, vol.21
, pp. 30-36
-
-
Silverman, D.N.1
Lindskog, S.2
-
6
-
-
57649155218
-
Entrapment of carbon dioxide in the active site of carbonic anhydrase II
-
Domsic J.F., Avvaru B.S., Kim C.U., Gruner S.M., Agbandje-McKenna M., Silverman D.N., and Mckenna R. Entrapment of carbon dioxide in the active site of carbonic anhydrase II. J. Biol. Chem. 283 (2008) 30766-30771
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 30766-30771
-
-
Domsic, J.F.1
Avvaru, B.S.2
Kim, C.U.3
Gruner, S.M.4
Agbandje-McKenna, M.5
Silverman, D.N.6
Mckenna, R.7
-
8
-
-
0009593678
-
Unexpected pH-dependent conformation of His-64, the proton shuttle of carbonic anhydrase-II
-
Nair S.K., and Christianson D.W. Unexpected pH-dependent conformation of His-64, the proton shuttle of carbonic anhydrase-II. J. Am. Chem. Soc. 113 (1991) 9455-9458
-
(1991)
J. Am. Chem. Soc.
, vol.113
, pp. 9455-9458
-
-
Nair, S.K.1
Christianson, D.W.2
-
9
-
-
33947414441
-
Atomic crystal and molecular dynamics simulation structures of human carbonic anhydrase II: insights into the proton transfer mechanism
-
Fisher S.Z., Maupin C.M., Budayova-Spano M., Govindasamy L., Tu C., Agbandje-McKenna M., Silverman D.N., Voth G.A., and McKenna R. Atomic crystal and molecular dynamics simulation structures of human carbonic anhydrase II: insights into the proton transfer mechanism. Biochemistry 46 (2007) 2930-2937
-
(2007)
Biochemistry
, vol.46
, pp. 2930-2937
-
-
Fisher, S.Z.1
Maupin, C.M.2
Budayova-Spano, M.3
Govindasamy, L.4
Tu, C.5
Agbandje-McKenna, M.6
Silverman, D.N.7
Voth, G.A.8
McKenna, R.9
-
10
-
-
0037102510
-
Kinetic characterization of wild-type and proton transfer-impaired variants of beta-carbonic anhydrase from Arabidopsis thaliana
-
Rowlett R.S., Tu C., McKay M.M., Preiss J.R., Loomis R.J., Hicks K.A., Marchione R.J., Strong J.A., Donovan Jr. G.S., and Chamberlin J.E. Kinetic characterization of wild-type and proton transfer-impaired variants of beta-carbonic anhydrase from Arabidopsis thaliana. Arch. Biochem. Biophys. 404 (2002) 197-209
-
(2002)
Arch. Biochem. Biophys.
, vol.404
, pp. 197-209
-
-
Rowlett, R.S.1
Tu, C.2
McKay, M.M.3
Preiss, J.R.4
Loomis, R.J.5
Hicks, K.A.6
Marchione, R.J.7
Strong, J.A.8
Donovan Jr., G.S.9
Chamberlin, J.E.10
-
11
-
-
0034622565
-
A structure-function study of a proton transport pathway in the gamma-class carbonic anhydrase from Methanosarcina thermophila
-
Tripp B.C., and Ferry J.G. A structure-function study of a proton transport pathway in the gamma-class carbonic anhydrase from Methanosarcina thermophila. Biochemistry 39 (2000) 9232-9240
-
(2000)
Biochemistry
, vol.39
, pp. 9232-9240
-
-
Tripp, B.C.1
Ferry, J.G.2
-
12
-
-
0034622579
-
A closer look at the active site of gamma-class carbonic anhydrases: high-resolution crystallographic studies of the carbonic anhydrase from Methanosarcina thermophila
-
Iverson T.M., Alber B.E., Kisker C., Ferry J.G., and Rees D.C. A closer look at the active site of gamma-class carbonic anhydrases: high-resolution crystallographic studies of the carbonic anhydrase from Methanosarcina thermophila. Biochemistry 39 (2000) 9222-9231
-
(2000)
Biochemistry
, vol.39
, pp. 9222-9231
-
-
Iverson, T.M.1
Alber, B.E.2
Kisker, C.3
Ferry, J.G.4
Rees, D.C.5
-
13
-
-
0033555131
-
Introduction of histidine analogs leads to enhanced proton transfer in carbonic anhydrase V
-
Earnhardt J.N., Wright S.K., Qian M.Z., Tu C.K., Laipis P.J., Viola R.E., and Silverman D.N. Introduction of histidine analogs leads to enhanced proton transfer in carbonic anhydrase V. Arch. Biochem. Biophys. 361 (1999) 264-270
-
(1999)
Arch. Biochem. Biophys.
, vol.361
, pp. 264-270
-
-
Earnhardt, J.N.1
Wright, S.K.2
Qian, M.Z.3
Tu, C.K.4
Laipis, P.J.5
Viola, R.E.6
Silverman, D.N.7
-
14
-
-
0037176904
-
Crystal structure of F65A/Y131C-methylimidazole carbonic anhydrase V reveals architectural features of an engineered proton shuttle
-
Jude K.M., Wright S.K., Tu C., Silverman D.N., Viola R.E., and Christianson D.W. Crystal structure of F65A/Y131C-methylimidazole carbonic anhydrase V reveals architectural features of an engineered proton shuttle. Biochemistry 41 (2002) 2485-2491
-
(2002)
Biochemistry
, vol.41
, pp. 2485-2491
-
-
Jude, K.M.1
Wright, S.K.2
Tu, C.3
Silverman, D.N.4
Viola, R.E.5
Christianson, D.W.6
-
15
-
-
34548724094
-
Solvent-mediated proton transfer in catalysis by carbonic anhydrase
-
Silverman D.N., and McKenna R. Solvent-mediated proton transfer in catalysis by carbonic anhydrase. Acc. Chem. Res. 40 (2007) 669-675
-
(2007)
Acc. Chem. Res.
, vol.40
, pp. 669-675
-
-
Silverman, D.N.1
McKenna, R.2
-
16
-
-
33947367836
-
Preferred orientations of His64 in human carbonic anhydrase II
-
Maupin C.M., and Voth G.A. Preferred orientations of His64 in human carbonic anhydrase II. Biochemistry 46 (2007) 2938-2947
-
(2007)
Biochemistry
, vol.46
, pp. 2938-2947
-
-
Maupin, C.M.1
Voth, G.A.2
-
17
-
-
67650513577
-
Elucidation of the proton transport mechanism in human carbonic anhydrase II
-
Maupin C.M., McKenna R., Silverman D.N., and Voth G.A. Elucidation of the proton transport mechanism in human carbonic anhydrase II. J. Am. Chem. Soc. 131 (2009) 7598-7608
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 7598-7608
-
-
Maupin, C.M.1
McKenna, R.2
Silverman, D.N.3
Voth, G.A.4
-
18
-
-
0027427176
-
Proton-transfer in the catalytic mechanism of carbonic-anhydrase. 2. Effects of placing histidine-residues at various positions in the active-site of human isoenzyme-II
-
Liang Z.W., Jonsson B.H., and Lindskog S. Proton-transfer in the catalytic mechanism of carbonic-anhydrase. 2. Effects of placing histidine-residues at various positions in the active-site of human isoenzyme-II. Biochim. Biophys. Acta 1203 (1993) 142-146
-
(1993)
Biochim. Biophys. Acta
, vol.1203
, pp. 142-146
-
-
Liang, Z.W.1
Jonsson, B.H.2
Lindskog, S.3
-
19
-
-
39749169756
-
Proton transfer in carbonic anhydrase is controlled by electrostatics rather than the orientation of the acceptor
-
Riccardi D., Konig P., Guo H., and Cui Q. Proton transfer in carbonic anhydrase is controlled by electrostatics rather than the orientation of the acceptor. Biochemistry 47 (2008) 2369-2378
-
(2008)
Biochemistry
, vol.47
, pp. 2369-2378
-
-
Riccardi, D.1
Konig, P.2
Guo, H.3
Cui, Q.4
-
20
-
-
0025946277
-
Conformational mobility of His-64 in the Thr200Ser mutant of human carbonic anhydrase-II
-
Krebs J.F., Fierke C.A., Alexander R.S., and Christianson D.W. Conformational mobility of His-64 in the Thr200Ser mutant of human carbonic anhydrase-II. Biochemistry 30 (1991) 9153-9160
-
(1991)
Biochemistry
, vol.30
, pp. 9153-9160
-
-
Krebs, J.F.1
Fierke, C.A.2
Alexander, R.S.3
Christianson, D.W.4
-
21
-
-
0020346412
-
Carbonic anhydrase: oxygen-18 exchange catalyzed by an enzyme with rate-contributing proton-transfer steps
-
Silverman D.N. Carbonic anhydrase: oxygen-18 exchange catalyzed by an enzyme with rate-contributing proton-transfer steps. Methods Enzymol. 87 (1982) 732-752
-
(1982)
Methods Enzymol.
, vol.87
, pp. 732-752
-
-
Silverman, D.N.1
-
22
-
-
33947684326
-
Speeding up proton transfer in a fast enzyme: kinetic and crystallographic studies on the effect of hydrophobic amino acid substitution in the active site of human carbonic anhydrase II
-
Fisher S.Z., Tu C.K., Bhatt D., Govindasamy L., Agbandje-McKenna M., McKenna R., and Silverman D.N. Speeding up proton transfer in a fast enzyme: kinetic and crystallographic studies on the effect of hydrophobic amino acid substitution in the active site of human carbonic anhydrase II. Biochemistry 42 (2007) 3803-3813
-
(2007)
Biochemistry
, vol.42
, pp. 3803-3813
-
-
Fisher, S.Z.1
Tu, C.K.2
Bhatt, D.3
Govindasamy, L.4
Agbandje-McKenna, M.5
McKenna, R.6
Silverman, D.N.7
-
23
-
-
56249123954
-
Role of hydrophilic residues in proton transfer during catalysis by human carbonic anhydrase II
-
Zheng J.Y., Avvaru B.S., Tu C., McKenna R., and Silverman D.N. Role of hydrophilic residues in proton transfer during catalysis by human carbonic anhydrase II. Biochemistry 47 (2008) 12028-12036
-
(2008)
Biochemistry
, vol.47
, pp. 12028-12036
-
-
Zheng, J.Y.1
Avvaru, B.S.2
Tu, C.3
McKenna, R.4
Silverman, D.N.5
-
24
-
-
0037022810
-
Chemical rescue in catalysis by human carbonic anhydrases II and III
-
An H., Tu C., Duda D., Montanez-Clemente I., Math K., Laipis P.J., McKenna R., and Silverman D.N. Chemical rescue in catalysis by human carbonic anhydrases II and III. Biochemistry 41 (2002) 3235-3242
-
(2002)
Biochemistry
, vol.41
, pp. 3235-3242
-
-
An, H.1
Tu, C.2
Duda, D.3
Montanez-Clemente, I.4
Math, K.5
Laipis, P.J.6
McKenna, R.7
Silverman, D.N.8
-
25
-
-
0027438252
-
Rate-equilibria relationships in intramolecular proton transfer in human carbonic anhydrase III
-
Silverman D.N., Tu C., Chen X., Tanhauser S.M., Kresge A.J., and Laipis P.J. Rate-equilibria relationships in intramolecular proton transfer in human carbonic anhydrase III. Biochemistry 32 (1993) 10757-10762
-
(1993)
Biochemistry
, vol.32
, pp. 10757-10762
-
-
Silverman, D.N.1
Tu, C.2
Chen, X.3
Tanhauser, S.M.4
Kresge, A.J.5
Laipis, P.J.6
-
26
-
-
0032823542
-
Application of Marcus rate theory to proton transfer in enzyme-catalyzed reactions
-
Kresge A.J., and Silverman D.N. Application of Marcus rate theory to proton transfer in enzyme-catalyzed reactions. Enzym. Kinet. Mech. Pt E 308 (1999) 276-297
-
(1999)
Enzym. Kinet. Mech.
, vol.PART E 308
, pp. 276-297
-
-
Kresge, A.J.1
Silverman, D.N.2
-
27
-
-
12344266417
-
Studies of proton translocations in biological systems: simulating proton transport in carbonic anhydrase by EVB-based models
-
Braun-Sand S., Strajbl M., and Warshel A. Studies of proton translocations in biological systems: simulating proton transport in carbonic anhydrase by EVB-based models. Biophys. J. 87 (2004) 2221-2239
-
(2004)
Biophys. J.
, vol.87
, pp. 2221-2239
-
-
Braun-Sand, S.1
Strajbl, M.2
Warshel, A.3
-
28
-
-
0037473097
-
Is a "proton wire" concerted or stepwise? A model study of proton transfer in carbonic anhydrase
-
Cui Q., and Karplus M. Is a "proton wire" concerted or stepwise? A model study of proton transfer in carbonic anhydrase. J. Phys. Chem. B 107 (2003) 1071-1078
-
(2003)
J. Phys. Chem. B
, vol.107
, pp. 1071-1078
-
-
Cui, Q.1
Karplus, M.2
-
29
-
-
0041843738
-
A computer simulation study of the hydrated proton in a synthetic proton channel
-
Wu Y., and Voth G.A. A computer simulation study of the hydrated proton in a synthetic proton channel. Biophys. J. 85 (2003) 864-875
-
(2003)
Biophys. J.
, vol.85
, pp. 864-875
-
-
Wu, Y.1
Voth, G.A.2
-
30
-
-
0035070279
-
The formation and dynamics of proton wires in channel environments
-
Brewer M.L., Schmitt U.W., and Voth G.A. The formation and dynamics of proton wires in channel environments. Biophys. J. 80 (2001) 1691-1702
-
(2001)
Biophys. J.
, vol.80
, pp. 1691-1702
-
-
Brewer, M.L.1
Schmitt, U.W.2
Voth, G.A.3
-
31
-
-
61849141323
-
A theory-experiment conundrum for proton transfer
-
Peters K.S. A theory-experiment conundrum for proton transfer. Acc. Chem. Res. 42 (2009) 89-96
-
(2009)
Acc. Chem. Res.
, vol.42
, pp. 89-96
-
-
Peters, K.S.1
-
32
-
-
34248165040
-
Tautomerism of histidine 64 associated with proton transfer in catalysis of carbonic anhydrase
-
Shimahara H., Yoshida T., Shibata Y., Shimizu M., Kyogoku Y., Sakiyama F., Nakazawa T., Tate S., Ohki S.Y., Kato T., Moriyama H., Kishida K., Tano Y., Ohkubo T., and Kobayashi Y. Tautomerism of histidine 64 associated with proton transfer in catalysis of carbonic anhydrase. J. Biol. Chem. 282 (2007) 9646-9656
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 9646-9656
-
-
Shimahara, H.1
Yoshida, T.2
Shibata, Y.3
Shimizu, M.4
Kyogoku, Y.5
Sakiyama, F.6
Nakazawa, T.7
Tate, S.8
Ohki, S.Y.9
Kato, T.10
Moriyama, H.11
Kishida, K.12
Tano, Y.13
Ohkubo, T.14
Kobayashi, Y.15
-
33
-
-
16244403026
-
Proton transfer from exogenous donors in catalysis by human carbonic anhydrase II
-
Elder I., Tu C.K., Ming L.J., McKenna R., and Silverman D.N. Proton transfer from exogenous donors in catalysis by human carbonic anhydrase II. Arch. Biochem. Biophys. 437 (2005) 106-114
-
(2005)
Arch. Biochem. Biophys.
, vol.437
, pp. 106-114
-
-
Elder, I.1
Tu, C.K.2
Ming, L.J.3
McKenna, R.4
Silverman, D.N.5
-
34
-
-
26444568636
-
Proton transfer in a Thr200His mutant of human carbonic anhydrase II
-
Bhatt D., Tu C., Fisher S.Z., Hernandez Prada J.A., McKenna R., and Silverman D.N. Proton transfer in a Thr200His mutant of human carbonic anhydrase II. Proteins 61 (2005) 239-245
-
(2005)
Proteins
, vol.61
, pp. 239-245
-
-
Bhatt, D.1
Tu, C.2
Fisher, S.Z.3
Hernandez Prada, J.A.4
McKenna, R.5
Silverman, D.N.6
-
35
-
-
13444269025
-
Structural and kinetic characterization of active-site histidine as a proton shuttle in catalysis by human carbonic anhydrase II
-
Fisher Z., Prada J.A.H., Tu C., Duda D., Yoshioka C., An H.Q., Govindasamy L., Silverman D.N., and McKenna R. Structural and kinetic characterization of active-site histidine as a proton shuttle in catalysis by human carbonic anhydrase II. Biochemistry 44 (2005) 1097-1105
-
(2005)
Biochemistry
, vol.44
, pp. 1097-1105
-
-
Fisher, Z.1
Prada, J.A.H.2
Tu, C.3
Duda, D.4
Yoshioka, C.5
An, H.Q.6
Govindasamy, L.7
Silverman, D.N.8
McKenna, R.9
-
36
-
-
33846417994
-
Location of binding sites in small molecule rescue of human carbonic anhydrase II
-
Bhatt D., Fisher S.Z., Tu C., McKenna R., and Silverman D.N. Location of binding sites in small molecule rescue of human carbonic anhydrase II. Biophys. J. 92 (2007) 562-570
-
(2007)
Biophys. J.
, vol.92
, pp. 562-570
-
-
Bhatt, D.1
Fisher, S.Z.2
Tu, C.3
McKenna, R.4
Silverman, D.N.5
|