Hypoxia-induced neuronal apoptosis is mediated by de novo synthesis of ceramide through activation of serine palmitoyltransferase

Cellular Signalling

Volumn 22, Issue 4, 2010, Pages 610-618

  Kang, Mi Sun ^a   Ahn, Kyong Hoon ^a   Kim, Seok Kyun ^a   Jeon, Hyung Jun ^a   Ji, Jung Eun ^a   Choi, Jong Min ^a   Jung, Kwang Mook ^a   Jung, Sung Yun ^a   Kim, Dae Kyong ^a  

^a Chung Ang University   (South Korea)

Author keywords

Apoptosis; Ceramidase; Ceramide; Glucosylceramide synthase; Hypoxia; Serine palmitoytransferase

Indexed keywords

2 DECANOYLAMINO 3 MORPHOLINO 1 PHENYL 1 PROPANOL; CASPASE INHIBITOR; CERAMIDE; CERAMIDE GLUCOSYLTRANSFERASE; CERAMIDE GLUCOSYLTRANSFERASE INHIBITOR; CYCLOSERINE; FUMONISIN B1; GLUCOSYLCERAMIDE; N OLEOYLETHANOLAMINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; SERINE PALMITOYLTRANSFERASE; SERINE PALMITOYLTRANSFERASE 2; SMALL INTERFERING RNA; SPHINGOSINE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL HYPOXIA; CELL LEVEL; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DNA FRAGMENTATION; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LIPOGENESIS; NERVE CELL NECROSIS; NEUROBLASTOMA CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; TRANSCRIPTION REGULATION;

APOPTOSIS; CELL HYPOXIA; CELL LINE, TUMOR; CERAMIDES; ENZYME INHIBITORS; ETHANOLAMINES; GLUCOSYLCERAMIDES; GLUCOSYLTRANSFERASES; HUMANS; MORPHOLINES; NEURONS; SERINE C-PALMITOYLTRANSFERASE; SPHINGOSINE;

EID: 74449084424     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2009.11.015     Document Type: Article

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