AURORA: Is There a Role for Statin Therapy in Dialysis Patients?

American Journal of Kidney Diseases

Volumn 55, Issue 2, 2010, Pages 237-240

  Shurraw, Sabin ^a   Tonelli, Marcello ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ATORVASTATIN; EZETIMIBE PLUS SIMVASTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; ROSUVASTATIN;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; CARDIOVASCULAR DISEASE; CHOLESTEROL BLOOD LEVEL; CLINICAL TRIAL; CREATINE KINASE BLOOD LEVEL; DEATH; EDITORIAL; HEART FAILURE; HEART INFARCTION; HEMODIALYSIS; HUMAN; KIDNEY DISEASE; MUSCLE DISEASE; SIDE EFFECT; STROKE; SURVIVAL;

EID: 74449084303     PISSN: 02726386     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.ajkd.2009.09.018     Document Type: Editorial

References (17)

1. US Renal Data System. USRDS 2008 Annual Data Report (2008), The National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD
2. Tonelli M., Isles C., Curhan G.C., et al. Effect of pravastatin on cardiovascular events in people with chronic kidney disease. Circulation 110 12 (2004) 1557-1563
3. Ridker P.M., Danielson E., Fonseca F.A., et al., JUPITER Trial Study Group. Reduction in C-reactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: a prospective study of the JUPITER trial. Lancet 373 9670 (2009) 1175-1182
4. Ridker P.M., Danielson E., Fonseca F.A., et al., JUPITER Study Group. Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. N Engl J Med 359 21 (2008) 2195-2207
5. Koenig W., Lowel H., Baumert J., and Meisinger C. C-Reactive protein modulates risk prediction based on the Framingham score: implications for future risk assessment: results from a large cohort study in southern Germany. Circulation 109 11 (2004) 1349-1353
6. Ridker P.M., Cannon C.P., Morrow D., et al., Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 (PROVE IT-TIMI 22) Investigators. C-Reactive protein levels and outcomes after statin therapy. N Engl J Med 352 1 (2005) 20-28
7. Fellstrom B.C., Jardine A.G., Schmieder R.E., et al., AURORA Study Group. Rosuvastatin and cardiovascular events in patients undergoing hemodialysis. N Engl J Med 360 14 (2009) 1395-1407
8. Seliger S.L., Weiss N.S., Gillen D.L., et al. HMG-Co A reductase inhibitors are associated with reduced mortality in ESRD patients. Kidney Int 61 1 (2002) 297-304
9. Mason N.A., Bailie G.R., Satayathum S., et al. HMG-coenzyme A reductase inhibitor use is associated with mortality reduction in hemodialysis patients. Am J Kidney Dis 45 1 (2005) 119-126
10. Wanner C., Krane V., März W., et al. Atorvastatin in patients with type 2 diabetes mellitus undergoing hemodialysis. N Engl J Med 353 3 (2005) 238-248
11. Krane V., Winkler K., Drechsler C., Lilienthal J., Marz W., and Wanner C. Effect of atorvastatin on inflammation and outcome in patients with type 2 diabetes mellitus on hemodialysis. Kidney Int 74 11 (2008) 1461-1467
12. Kearney P.M., Blackwell L., Collins R., et al., Cholesterol Treatment Trialists' (CTT) Collaborators. Efficacy of cholesterol-lowering therapy in 18,686 people with diabetes in 14 randomised trials of statins: a meta-analysis. Lancet 371 9607 (2008) 117-125
13. Wanner C. Statin effects in CKD: is there a "point of no return"?. Am J Kidney Dis 53 5 (2009) 723-725
14. Herzog C.A. How to manage the renal patient with coronary heart disease: the agony and the ecstasy of opinion-based medicine. J Am Soc Nephrol 14 10 (2003) 2556-2572
15. Karnik J.A., Young B.S., Lew N.L., et al. Cardiac arrest and sudden death in dialysis units. Kidney Int 60 1 (2001) 350-357
16. London G.M., Marchais S.J., Metivier F., and Guerin A.P. Cardiovascular risk in end-stage renal disease: vascular aspects. Nephrol Dial Transplant 15 suppl 5 (2000) 97-104
17. Kjekshus J., Apetrei E., Barrios V., et al. Rosuvastatin in older patients with systolic heart failure. N Engl J Med 357 22 (2007) 2248-2261