메뉴 건너뛰기




Volumn 4, Issue SUPPL. 2, 2004, Pages

Can inhibition of angiogenic pathways increase the efficacy of intravenous 5-fluorouracil-based regimens?

Author keywords

Bevacizumab; Combination therapy; Hypertension; Leucovorin; Proteinuria; Vascular endothelial growth factor

Indexed keywords

ALBUMIN; ANTHRACYCLINE; BEVACIZUMAB; CAPECITABINE; FLUOROURACIL; FOLINIC ACID; IRINOTECAN; OXALIPLATIN; PLACEBO; VASCULOTROPIN INHIBITOR;

EID: 7444252791     PISSN: 15330028     EISSN: None     Source Type: Journal    
DOI: 10.3816/CCC.2004.s.011     Document Type: Article
Times cited : (8)

References (15)
  • 1
    • 0028971501 scopus 로고
    • VEGF165 expressed by a replication-deficient recombinant adenovirus vector induces angiogenesis in vivo
    • Muhlhauser J, Merrill MJ, Pili R, et al. VEGF165 expressed by a replication-deficient recombinant adenovirus vector induces angiogenesis in vivo. Circ Res 1995; 77:1077-1086.
    • (1995) Circ. Res. , vol.77 , pp. 1077-1086
    • Muhlhauser, J.1    Merrill, M.J.2    Pili, R.3
  • 2
    • 0030700901 scopus 로고    scopus 로고
    • Association of vascular endothelial growth factor expression with tumor angiogenesis, survival and thymidine phosphorylase/platelet-derived endothelial cell growth factor expression in human colorectal cancer
    • Amaya H, Tanigawa N, Lu C, et al. Association of vascular endothelial growth factor expression with tumor angiogenesis, survival and thymidine phosphorylase/platelet-derived endothelial cell growth factor expression in human colorectal cancer. Cancer Lett 1997; 119:227-235.
    • (1997) Cancer Lett. , vol.119 , pp. 227-235
    • Amaya, H.1    Tanigawa, N.2    Lu, C.3
  • 3
    • 0031897495 scopus 로고    scopus 로고
    • Involvement of vascular endothelial growth factor and urokinase-type plasminogen activator receptor in microvessel invasion in human colorectal cancers
    • Nakata S, Ito K, Fujimori M, et al. Involvement of vascular endothelial growth factor and urokinase-type plasminogen activator receptor in microvessel invasion in human colorectal cancers. Int J Cancer 1998; 79:179-186.
    • (1998) Int. J. Cancer , vol.79 , pp. 179-186
    • Nakata, S.1    Ito, K.2    Fujimori, M.3
  • 4
    • 2942547168 scopus 로고    scopus 로고
    • The addition of bevacizumab (anti-VEGF) to FOLFOX4 in previously treated advanced colorectal cancer (adv CRC): An updated interim analysis of the Eastern Cooperative Oncology Group (ECOG) study E3200
    • January 22-24, San Francisco, CA. Abstract #241
    • Giantonio BJ, Catalano PJ, Meropol NJ et al. The addition of bevacizumab (anti-VEGF) to FOLFOX4 in previously treated advanced colorectal cancer (adv CRC): an updated interim analysis of the Eastern Cooperative Oncology Group (ECOG) study E3200. In: Proceedings of the 2004 Gastrointestinal Cancers Symposium; January 22-24, 2004; San Francisco, CA. Abstract #241.
    • (2004) Proceedings of the 2004 Gastrointestinal Cancers Symposium
    • Giantonio, B.J.1    Catalano, P.J.2    Meropol, N.J.3
  • 5
    • 7444245560 scopus 로고    scopus 로고
    • Bevacizumab in combination with 5-flourouracil and leucovorin: A promising regimen for first-line metastatic colorectal cancer
    • January 22-24, San Francisco, CA. Abstract #286
    • Hurwitz H, Fehrenbacher L, Hainsworth J, et al. Bevacizumab in combination with 5-flourouracil and leucovorin: a promising regimen for first-line metastatic colorectal cancer. In: Proceedings of the 2004 Gastrointestinal Cancers Symposium; January 22-24, 2004; San Francisco, CA. Abstract #286.
    • (2004) Proceedings of the 2004 Gastrointestinal Cancers Symposium
    • Hurwitz, H.1    Fehrenbacher, L.2    Hainsworth, J.3
  • 6
    • 0037208589 scopus 로고    scopus 로고
    • Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer
    • Kabbinavar F, Hurwitz HI, Fehrenbacher L, et al. Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer. J Clin Oncol 2003; 21:60-65.
    • (2003) J. Clin. Oncol. , vol.21 , pp. 60-65
    • Kabbinavar, F.1    Hurwitz, H.I.2    Fehrenbacher, L.3
  • 7
    • 0033913981 scopus 로고    scopus 로고
    • Prognostic factors for tumour response, progression-free survival and toxicity in metastatic colorectal cancer patients given irinotecan (CPT-11) as second-line chemotherapy after 5FU failure
    • CPT-11 F205, F220, F221 and V222 study groups
    • Freyer G, Rougier P, Bugat R, et al. Prognostic factors for tumour response, progression-free survival and toxicity in metastatic colorectal cancer patients given irinotecan (CPT-11) as second-line chemotherapy after 5FU failure. CPT-11 F205, F220, F221 and V222 study groups. Br J Cancer 2000; 83:431-437.
    • (2000) Br. J. Cancer , vol.83 , pp. 431-437
    • Freyer, G.1    Rougier, P.2    Bugat, R.3
  • 8
    • 2642529751 scopus 로고    scopus 로고
    • Is age a prognostic factor of toxicity and efficacy in patients (pts) with metastatic colorectal cancer (MCRC) receiving irinotecan in combination with 5FU/folinic acid (FA)
    • (Abstract #1072)
    • Rougier P, Mitry E, Cunningham D, et al. Is age a prognostic factor of toxicity and efficacy in patients (pts) with metastatic colorectal cancer (MCRC) receiving irinotecan in combination with 5FU/folinic acid (FA). Proc Am Soc Clin Oncol 2003; 22:267 (Abstract #1072).
    • (2003) Proc. Am. Soc. Clin. Oncol. , vol.22 , pp. 267
    • Rougier, P.1    Mitry, E.2    Cunningham, D.3
  • 9
    • 0034727063 scopus 로고    scopus 로고
    • Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer
    • Irinotecan Study Group
    • Saltz LB, Cox JV, Blanke C, et al. Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. Irinotecan Study Group. N Engl J Med 2000; 343:905-914.
    • (2000) N. Engl. J. Med. , vol.343 , pp. 905-914
    • Saltz, L.B.1    Cox, J.V.2    Blanke, C.3
  • 10
    • 0038598980 scopus 로고    scopus 로고
    • Evaluation of age, gender, performance status (PS), and organ dysfunction as predictors of toxicity with first-line irinotecan (C), fluorouracil (F), leucovorin (L) therapy of metastatic colorectal cancer (MCRC)
    • (Abstract #534)
    • Knight RD, Miller L, Elfring G, et al. Evaluation of age, gender, performance status (PS), and organ dysfunction as predictors of toxicity with first-line irinotecan (C), fluorouracil (F), leucovorin (L) therapy of metastatic colorectal cancer (MCRC). Proc Am Soc Clin Oncol 2001; 20:534 (Abstract #534).
    • (2001) Proc. Am. Soc. Clin. Oncol. , vol.20 , pp. 534
    • Knight, R.D.1    Miller, L.2    Elfring, G.3
  • 11
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004; 350:2335-2342.
    • (2004) N. Engl. J. Med. , vol.350 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3
  • 12
    • 84898692628 scopus 로고    scopus 로고
    • Results of a randomized, phase II controlled trial of bevacizumab in combination with 5-fluourouracil and leucovorin as first-line therapy in subjects with metastatic CRC
    • (Abstract #3516)
    • Kabbinavar F, Schultz J, McCleod M, et al. Results of a randomized, phase II controlled trial of bevacizumab in combination with 5-fluourouracil and leucovorin as first-line therapy in subjects with metastatic CRC. Proc Am Soc Clin Oncol 2004; 23:249 (Abstract #3516).
    • (2004) Proc. Am. Soc. Clin. Oncol. , vol.23 , pp. 249
    • Kabbinavar, F.1    Schultz, J.2    McCleod, M.3
  • 13
    • 4444264576 scopus 로고    scopus 로고
    • Bevacizumab (Avastin) in combination with 5-FU/leucovorin improves survival in patients with metastatic colorectal cancer: A combined analysis
    • (Abstract #3616)
    • Mass R, Fyfe G, Hambleton J, et al. Bevacizumab (Avastin) in combination with 5-FU/leucovorin improves survival in patients with metastatic colorectal cancer: a combined analysis. Proc Am Soc Clin Oncol 2004; 23:274 (Abstract #3616).
    • (2004) Proc. Am. Soc. Clin. Oncol. , vol.23 , pp. 274
    • Mass, R.1    Fyfe, G.2    Hambleton, J.3
  • 14
    • 84898691809 scopus 로고    scopus 로고
    • Avastin [package insert]. South San Francisco, CA: Genentech
    • Avastin [package insert]. South San Francisco, CA: Genentech, 2004.
    • (2004)
  • 15
    • 7444224685 scopus 로고    scopus 로고
    • Integrating anti-VEGF-A humanized monoclonal antibody bevacizumab with chemotherapy in advanced colorectal cancer
    • Hurwitz H. Integrating anti-VEGF-A humanized monoclonal antibody bevacizumab with chemotherapy in advanced colorectal cancer. Clin Colorectal Cancer 2004; 4(suppl):S62-S68.
    • (2004) Clin. Colorectal Cancer , Issue.4 SUPPL.
    • Hurwitz, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.