Zn overdose may cause disturbance in iron metabolism in inactive inflammatory bowel diseases

Trace Elements and Electrolytes

Volumn 21, Issue 4, 2004, Pages 240-247

  Blazovics A ^a,b   Szentmihalyi K ^b   Vinkler, P ^b   Kovacs A ^c  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b CHEMICAL RESEARCH CENTER   (Hungary)

^c Peterfy Sandor Hospital   (Hungary)

Author keywords

Inflammatory bowel diseases; Redox reactions; Trace elements

Indexed keywords

COPPER; IRON; POTASSIUM; SODIUM; SULFUR; ZINC;

ADULT; ARTICLE; BLOOD ANALYSIS; CAUCASIAN; CHEMOLUMINESCENCE; CLINICAL ARTICLE; CONTROLLED STUDY; COPPER DEFICIENCY; ENTERITIS; ENZYME ACTIVITY; ERYTHROCYTE; FEMALE; HEALTH HAZARD; HUMAN; INTOXICATION; IRON DEFICIENCY; IRON METABOLISM; MALE; METABOLIC DISORDER; NUTRITIONAL SUPPORT; OXIDATION REDUCTION REACTION; OXIDATION REDUCTION STATE; PLASMA; PRIORITY JOURNAL; SPECTROPHOTOMETRY; ZINC DEFICIENCY; ZINC OVERDOSE;

EID: 7444251698     PISSN: 09462104     EISSN: None     Source Type: Journal    
DOI: 10.5414/tep21240     Document Type: Article

References (33)

1. Ainley CC, Cason J, Carlsson LK, Slavin BM, Thompson RP 1988 Zinc status in inflammatory bowel disease. Clin Sci 75: 277-283
2. Belluzzi A, Brignola C, Campieri M, Gionchetti P, Rizzello F, Boschi S, Cunanne S, Miglioli M, Barbara L 1994 Short report: zinc sulphate supplementation corrects abnormal erythrocyte membrane long-chain fatty acid composition in patients with Crohn's disease. Aliment Pharmacol Ther 8: 127-130
3. Best WR, Becktel JM, Singleton JW, Kern F Jr 1976 Development of Crohn's disease activity index. Gastroenterology 70: 439-444
4. Bhaskar L, Ramakrishna BS, Balasubramanian KA 1995 Colonic mucosal antioxidant enzymes and lipid peroxide levels in normal subjects and patients with ulcerative colitis. J Gastroenterol Hepatol 10: 140-143
5. Blázovics A, Kovács Á, Lugasi A, Hagymási K, Bíró L, Fehér J 1999 Antioxidant defence in erythrocytes and plasma of patients with active and quiescent Crohn's disease and ulcerative colitis: a chemiluminescent study. Clin Chem 45: 895-896
6. Blázovics A, Kovács Á, Lugasi A, Hagymási K, Bíró L, Fehér J 2000 Total scavenger capacity of erythrocytes and plasma is a good predictive factor in inflammatory bowel diseases. Curr Top Biophys 24: 19-28
7. Blois MS 1958 Antioxidant determination by the use of stable free radicals. Nature 4617: 1199-2000
8. Buffinton GD, Doe W 1995 Depleted mucosal antioxidant defenses in inflammatory bowel disease. Free Radic Biol Med 19: 911-918
9. Chandra R 1999 Nutrition and immunology: from the clinic to cellular biology and back again. Proc Nutr Soc 58: 681-683
10. Cousins RJ, McMahon RJ 2000 Integrative aspects of Zn transporters. J Nutr 130: 1384S-1387S
11. Dalekos GN, Ringstad J, Savaidis I, Seferiadis KI, Tsianos EV 1998 Zinc, copper and immunological markers in the circulation of well-nourished patients with ulcerative colitis. Eur J Gastroenterol Hepatol 10: 331-337
12. Di Leo V, D'Inca R, Barollo M, Tropea A, Fries W, Mazzon E, Irato P, Lecchetto A, Sturniolo GC 2001 Effect of zinc supplementation trace elements and intestinal metallothionein concentrations in experimental colitis in the rat. Dig Liver Dis 33: 135-139
13. Failla ML 1999 Considerations for determining "optimal nutrition" for copper, zinc, manganese and molybdenum. Proc Nutr Soc 58: 497-505
14. Ghos S, Meister D 2000 Osteopenia in inflammatory bowel disease. Res Klein Forums 22: 159-170
15. Gokhale R, Favas MJ, Karrison T, Suttou MM, Rich B, Kirschner BS 1999 Bone mineral density assessment in children with inflammatory bowel disease. Gastroenterology 114: 902-911
16. Hatano T, Kagawa H, Yasuhara T, Okuda T 1988 Two new flavonoids and other constituents in licore root: their relative astringency and radical scavenging effects. Chem Pharm Bull 36: 2090-2097
17. Jacobson S, Plantin LO 1985 Concentration of selenium in plasma and erythrocytes during total parenteral nutriton in Crohn's disease. Gut 26: 50-54
18. Jankowski-Hennig MA, Clegg MS, Daston GP, Rogers JM, Keen CL 2000 Zinc-deficient rat embryos have increased caspase 3-like activity and apoptosis. Biochem Biophys Res Commun 271: 250-256
19. King JC, Shames DM, Lowe NM, Woodhouse LR, Sutherland B, Abrams SA, Turnlund JR, Jackson MJ 2001 Effect of acute zinc depletion on zinc homeostasis and plasma zinc kinetics in men. Am J Clin Nutr 74: 116-124
20. Kovatsi L, Tsouggas M 2002 The effect of oral aspartame administration on the excretion and the distribution of zinc in rat tissues. Trace Elem Electrolytes 19: 11-14
21. McKenzie SJ, Baker S, Buffinton GD, Doe WP 1996 Evidence of oxidant-induced injury to epithelial cells during inflammatory bowel disease. J Clin Invest 98: 136-141
22. Nielsen OH, Rask-Madsen J 1996 Mediators of inflammation in chronic inflammatory bowel disease. Scand J Gastroenterol Suppl 216: 149-159
23. Oyaizu M 1986 Studies on products of browning reaction prepared from glucosamine. Jpn J Nutr 44: 307-315
24. Pearson DC, Jourd Heuil D, Headings JB 1996 The anti-oxidant properties of 5-aminosalicylic acid. Free Radic Biol Med 21: 367-373
25. Rannem T, Ladefoged K, Hylander E, Hegnhoj J, Jarnum S 1992 Selenium status in patients with Crohn's disease. Am J Clin Nutr 56: 933-937
26. Roth HP, Kirchgessner M1998 Calmodulin, zinc and calcium concentration in tissues of zinc- and calcium-deficient rats. J Trace Elem Electrolytes Health Dis 2: 73-78
27. Sedlak J, Lindsay RH 1985 Estimation of total protein-bound and nonprotein sulfhydryl groups in tissues with Ellmann's reagent. Anal Biochem Biophys 25: 192-205
28. Szczurek EI, Bjornsson CS, Taylor CG 2001 Dietary zinc deficiency and repletion modulate metallothionein immunolocalization and concentration in small intestine and liver of rats. J Nutr 131: 2132-2138
29. Szentmihályi K, Blázovics A, Kocsis I, Fehér E, Lakatos B, Vinkler P 2000 The effect of fat rich diet and alcohol on ion concentration in bile in rats. Acta Alim 29: 359-366
30. Tekeli SK 2002 the study of effects on serum glucose, total lipid, total protein and albumin levels of orally zinc in rats. Trace Elem Electrolytes 19: 6-10
31. Tominaga M, Iida M, Aoyagi K, Kohrogi N, Matsui T, Fujishima M 1989 Red cell folate concentrations in patients with Crohn's disease on parenteral nutrition. Postgrad Med J 65: 818-820
32. Tragnone Valpiani D, Miglio F, Elmi G, Bazzocchi G, Pipitone E, Lafranchi GA 1995 Dietary habits as risk factors for inflammatory bowel disease. Eur J Gastroenterol Hepatol 7: 47-51
33. Van de Wal Y, Van der Sluys Veer A, Verspaget HW, Mulder TP, Griffioen G, Van Tol EA, Pena AS, Lamers CB 1993 Effect of zinc therapy on natural killer cell activity in inflammatory bowel disease. Aliment Pharmacol Ther 37: 281-286