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Volumn 23, Issue 3, 2004, Pages 1161-1167

In vivo occupancy of female rat brain estrogen receptors by 17β-estradiol and tamoxifen

Author keywords

11 Methoxy 16 125I iodo estradiol; 16 18F fluoroestradiol; Autoradiography; SERMs

Indexed keywords

ESTRADIOL; ESTROGEN RECEPTOR; TAMOXIFEN;

EID: 7444243825     PISSN: 10538119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2004.07.036     Document Type: Article
Times cited : (21)

References (51)
  • 1
    • 0028340042 scopus 로고
    • TAM administration is associated with a high rate of treatment-limiting symptoms in male breast cancer patients
    • T.F. Anelli, A. Anelli, K.N. Tran, D.E. Lebwohl, and P.I. Borgen TAM administration is associated with a high rate of treatment-limiting symptoms in male breast cancer patients Cancer 74 1 1994 74 77
    • (1994) Cancer , vol.74 , Issue.1 , pp. 74-77
    • Anelli, T.F.1    Anelli, A.2    Tran, K.N.3    Lebwohl, D.E.4    Borgen, P.I.5
  • 2
    • 0032517113 scopus 로고    scopus 로고
    • Estradiol prevents kainic acid-induced neuronal loss in the rat dentate gyrus
    • I. Azcoitia, A. Sierra, and L.M. Garcia-Segura Estradiol prevents kainic acid-induced neuronal loss in the rat dentate gyrus NeuroReport 9(13) 1998 3075 3079
    • (1998) NeuroReport , vol.913 , pp. 3075-3079
    • Azcoitia, I.1    Sierra, A.2    Garcia-Segura, L.M.3
  • 3
    • 0036593191 scopus 로고    scopus 로고
    • Oestrogen as a neuroprotective hormone
    • C. Behl Oestrogen as a neuroprotective hormone Nat. Rev., Neurosci. 3 6 2002 433 442
    • (2002) Nat. Rev., Neurosci. , vol.3 , Issue.6 , pp. 433-442
    • Behl, C.1
  • 4
    • 0020057723 scopus 로고
    • Modulation by estradiol of serotonin receptors in the brain
    • A. Biegon, and B.S. McEwen Modulation by estradiol of serotonin receptors in the brain J. Neurosci. 2 2 1982 199 205
    • (1982) J. Neurosci. , vol.2 , Issue.2 , pp. 199-205
    • Biegon, A.1    McEwen, B.S.2
  • 5
    • 0029758023 scopus 로고    scopus 로고
    • A permanently charged TAM derivative displays anticancer activity and improved tissue selectivity in rodents
    • A. Biegon, M. Brewster, H. Degani, E. Pop, D. Somjen, and A.M. Kaye A permanently charged TAM derivative displays anticancer activity and improved tissue selectivity in rodents Cancer Res. 56 19 1996 4328 4331
    • (1996) Cancer Res. , vol.56 , Issue.19 , pp. 4328-4331
    • Biegon, A.1    Brewster, M.2    Degani, H.3    Pop, E.4    Somjen, D.5    Kaye, A.M.6
  • 7
    • 0024599289 scopus 로고
    • Characterization of 11beta-methoxy-16alpha-[125I]iodoestradiol binding: Neuronal localization of estrogen-binding sites in the developing brain
    • T.J. Brown, N.J. MacLusky, C.D. Toran-Allerand, J.E. Zielinski, and R.B. Hochberg Characterization of 11beta-methoxy-16alpha-[125I]iodoestradiol binding: neuronal localization of estrogen-binding sites in the developing brain Endocrinology 124 5 1989 2074 2088
    • (1989) Endocrinology , vol.124 , Issue.5 , pp. 2074-2088
    • Brown, T.J.1    MacLusky, N.J.2    Toran-Allerand, C.D.3    Zielinski, J.E.4    Hochberg, R.B.5
  • 8
    • 0030059617 scopus 로고    scopus 로고
    • Regulation of estrogen receptor concentrations in the rat brain: Effects of sustained androgen and estrogen exposure
    • T.J. Brown, B. Scherz, R.B. Hochberg, and N.J. MacLusky Regulation of estrogen receptor concentrations in the rat brain: effects of sustained androgen and estrogen exposure Neuroendocrinology 63 1996 53 60
    • (1996) Neuroendocrinology , vol.63 , pp. 53-60
    • Brown, T.J.1    Scherz, B.2    Hochberg, R.B.3    MacLusky, N.J.4
  • 10
    • 0034989986 scopus 로고    scopus 로고
    • Estrogen-like activity of tamoxifen and raloxifene on NMDA receptor binding and expression of its subunits in rat brain
    • M. Cyr, C. Thibault, M. Morissette, M. Landry, and T. Di Paolo Estrogen-like activity of tamoxifen and raloxifene on NMDA receptor binding and expression of its subunits in rat brain Neuropsychopharmacology 25 2 2001 242 257
    • (2001) Neuropsychopharmacology , vol.25 , Issue.2 , pp. 242-257
    • Cyr, M.1    Thibault, C.2    Morissette, M.3    Landry, M.4    Di Paolo, T.5
  • 11
    • 0842334814 scopus 로고    scopus 로고
    • Characterization of a membrane-associated estrogen receptor in a rat hypothalamic cell line (D12)
    • D.C. Deecher, P. Swiggard, D.E. Frail, and L.T. O'Connor Characterization of a membrane-associated estrogen receptor in a rat hypothalamic cell line (D12) Endocrine 22 3 2003 211 223
    • (2003) Endocrine , vol.22 , Issue.3 , pp. 211-223
    • Deecher, D.C.1    Swiggard, P.2    Frail, D.E.3    O'Connor, L.T.4
  • 15
    • 1642492958 scopus 로고    scopus 로고
    • Estrogen- and tamoxifen-associated effects on brain structure and function
    • J.L. Eberling, C. Wu, R. Tong-Turnbeaugh, and W.J. Jagust Estrogen- and tamoxifen-associated effects on brain structure and function NeuroImage 21 1 2004 364 371
    • (2004) NeuroImage , vol.21 , Issue.1 , pp. 364-371
    • Eberling, J.L.1    Wu, C.2    Tong-Turnbeaugh, R.3    Jagust, W.J.4
  • 17
    • 0033304703 scopus 로고    scopus 로고
    • Tamoxifen, raloxifene and the prevention of breast cancer
    • V.C. Jordan, and M. Morrow Tamoxifen, raloxifene and the prevention of breast cancer Endocr. Rev. 20 3 1999 253 278
    • (1999) Endocr. Rev. , vol.20 , Issue.3 , pp. 253-278
    • Jordan, V.C.1    Morrow, M.2
  • 18
    • 0037435046 scopus 로고    scopus 로고
    • Antiestrogens and selective estrogen receptor modulators as multifunctional medicines. 1. Receptor interactions
    • V.C. Jordan Antiestrogens and selective estrogen receptor modulators as multifunctional medicines. 1. Receptor interactions J. Med. Chem. 46 6 2003 884 908
    • (2003) J. Med. Chem. , vol.46 , Issue.6 , pp. 884-908
    • Jordan, V.C.1
  • 19
    • 0026776408 scopus 로고
    • Estrogen suppresses mu-opiod- and GABAB-mediated hyperpolarization of hypothalamic arcuate neurons
    • M.J. Kelly, M.D. Loose, and O.K. Ronnekleiv Estrogen suppresses mu-opiod- and GABAB-mediated hyperpolarization of hypothalamic arcuate neurons J. Neurosci. 12 7 1992 2745 2750
    • (1992) J. Neurosci. , vol.12 , Issue.7 , pp. 2745-2750
    • Kelly, M.J.1    Loose, M.D.2    Ronnekleiv, O.K.3
  • 20
    • 0037970171 scopus 로고    scopus 로고
    • Neuroprotective activity of tamoxifen in permanent focal ischemia
    • H.K. Kimelberg, Y. Jin, C. Charniga, and P.J. Feustel Neuroprotective activity of tamoxifen in permanent focal ischemia J. Neurosurg. 99 1 2003 138 142
    • (2003) J. Neurosurg. , vol.99 , Issue.1 , pp. 138-142
    • Kimelberg, H.K.1    Jin, Y.2    Charniga, C.3    Feustel, P.J.4
  • 21
    • 0029156595 scopus 로고
    • Estrogen replacement therapy may protect against intellectual decline in postmenopausal women
    • D. Kimura Estrogen replacement therapy may protect against intellectual decline in postmenopausal women Horm. Behav. 29 3 1995 312 321
    • (1995) Horm. Behav. , vol.29 , Issue.3 , pp. 312-321
    • Kimura, D.1
  • 22
    • 0042386108 scopus 로고    scopus 로고
    • Acute influence of estrogen and testosterone on divergent and convergent thinking in postmenopausal women
    • R. Krug, M. Mölle, C. Dodt, H.L. Fehm, and J. Born Acute influence of estrogen and testosterone on divergent and convergent thinking in postmenopausal women Neuropsychopharmacology 28 8 2003 1538 1545
    • (2003) Neuropsychopharmacology , vol.28 , Issue.8 , pp. 1538-1545
    • Krug, R.1    Mölle, M.2    Dodt, C.3    Fehm, H.L.4    Born, J.5
  • 24
    • 0031039888 scopus 로고    scopus 로고
    • Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta
    • G.G. Kuiper, B. Carlsson, K. Grandien, E. Enmark, J. Haggblad, S. Nilsson, and J.A. Gustafsson Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta Endocrinology 138 3 1997 863 870
    • (1997) Endocrinology , vol.138 , Issue.3 , pp. 863-870
    • Kuiper, G.G.1    Carlsson, B.2    Grandien, K.3    Enmark, E.4    Haggblad, J.5    Nilsson, S.6    Gustafsson, J.A.7
  • 25
    • 0032487057 scopus 로고    scopus 로고
    • Expression and neuropeptidergic characterization of estrogen receptors (ERα and ERβ) throughout the rat brain: Anatomical evidence of distinct roles of each subtype
    • N. Laflamme, R.E. Nappi, G. Drolet, C. Labrie, and S. Rivest Expression and neuropeptidergic characterization of estrogen receptors (ERα and ERβ) throughout the rat brain: anatomical evidence of distinct roles of each subtype J. Neurobiol. 36 3 1998 357 378
    • (1998) J. Neurobiol. , vol.36 , Issue.3 , pp. 357-378
    • Laflamme, N.1    Nappi, R.E.2    Drolet, G.3    Labrie, C.4    Rivest, S.5
  • 26
    • 0030978296 scopus 로고    scopus 로고
    • Modulation of G protein-coupled receptors by an estrogen receptor that activates protein kinase a
    • A.H. Lagrange, O.K. Ronnekleiv, and M.J. Kelly Modulation of G protein-coupled receptors by an estrogen receptor that activates protein kinase A Mol. Pharmacol. 51 4 1997 605 612
    • (1997) Mol. Pharmacol. , vol.51 , Issue.4 , pp. 605-612
    • Lagrange, A.H.1    Ronnekleiv, O.K.2    Kelly, M.J.3
  • 27
    • 0030272778 scopus 로고    scopus 로고
    • The use of 3-methoxymethyl-16 beta, 17 beta-epiestriol-O-cyclic sulfone as the precursor in the synthesis of F-18 16 alpha-fluoroestradiol
    • J.L. Lim, L. Zheng, M.S. Berridge, and T.J. Tewson The use of 3-methoxymethyl-16 beta, 17 beta-epiestriol-O-cyclic sulfone as the precursor in the synthesis of F-18 16 alpha-fluoroestradiol Nucl. Med. Biol. 23 7 1996 911 915
    • (1996) Nucl. Med. Biol. , vol.23 , Issue.7 , pp. 911-915
    • Lim, J.L.1    Zheng, L.2    Berridge, M.S.3    Tewson, T.J.4
  • 28
    • 0023878496 scopus 로고    scopus 로고
    • Autoradiographic localization of estradiol-binding neurons in the rat hippocampal formation and entorhinal cortex
    • R. Loy, J.L. Gerlach, and B.S. McEwen Autoradiographic localization of estradiol-binding neurons in the rat hippocampal formation and entorhinal cortex Brain Res. 467 2 1998 245 251
    • (1998) Brain Res. , vol.467 , Issue.2 , pp. 245-251
    • Loy, R.1    Gerlach, J.L.2    McEwen, B.S.3
  • 29
    • 0030786893 scopus 로고    scopus 로고
    • Analysis of blood clearance and labeled metabolites for the estrogen receptor tracer [F-18]-16 alpha-fluoroestradiol (FES)
    • D.A. Mankoff, T.J. Tewson, and J.F. Eary Analysis of blood clearance and labeled metabolites for the estrogen receptor tracer [F-18]-16 alpha-fluoroestradiol (FES) Nucl. Med. Biol. 24 4 1997 341 348
    • (1997) Nucl. Med. Biol. , vol.24 , Issue.4 , pp. 341-348
    • Mankoff, D.A.1    Tewson, T.J.2    Eary, J.F.3
  • 30
    • 0037378915 scopus 로고    scopus 로고
    • Uncoupling of 5-HT1A receptors in the brain by estrogens: Regional variations in antagonism by ICI 182,780
    • A.L. Mize, L.J. Young, and R.H. Alper Uncoupling of 5-HT1A receptors in the brain by estrogens: regional variations in antagonism by ICI 182,780 Neuropharmacology 44 5 2003 584 591
    • (2003) Neuropharmacology , vol.44 , Issue.5 , pp. 584-591
    • Mize, A.L.1    Young, L.J.2    Alper, R.H.3
  • 31
    • 0028834173 scopus 로고
    • Systemic and cerebral kinetics of 16 alpha [18F]fluoro-17 beta-estradiol: A ligand for the in vivo assessment of estrogen receptor binding parameters
    • R.M. Moresco, R. Casati, G. Lucignani, A. Carpinelli, K. Schmidt, S. Todde, F. Colombo, and F. Fazio Systemic and cerebral kinetics of 16 alpha [18F]fluoro-17 beta-estradiol: a ligand for the in vivo assessment of estrogen receptor binding parameters J. Cereb. Blood Flow Metab. 15 2 1995 301 311
    • (1995) J. Cereb. Blood Flow Metab. , vol.15 , Issue.2 , pp. 301-311
    • Moresco, R.M.1    Casati, R.2    Lucignani, G.3    Carpinelli, A.4    Schmidt, K.5    Todde, S.6    Colombo, F.7    Fazio, F.8
  • 32
    • 0029979129 scopus 로고    scopus 로고
    • Positron emission tomography with 2-[18F]Fluoro-2-deoxy-d-glucose and 16alpha-[18F]fluoro-17beta-estradiol in breast cancer: Correlation with estrogen receptor status and response to systemic therapy
    • J.E. Mortimer, F. Dehdashti, B.A. Siegel, J.A. Katzenellenbogen, P. Fracasso, and M.J. Welch Positron emission tomography with 2-[18F]Fluoro-2- deoxy-d-glucose and 16alpha-[18F]fluoro-17beta-estradiol in breast cancer: correlation with estrogen receptor status and response to systemic therapy Clin. Cancer Res. 2 6 1996 933 939
    • (1996) Clin. Cancer Res. , vol.2 , Issue.6 , pp. 933-939
    • Mortimer, J.E.1    Dehdashti, F.2    Siegel, B.A.3    Katzenellenbogen, J.A.4    Fracasso, P.5    Welch, M.J.6
  • 33
    • 0031910162 scopus 로고    scopus 로고
    • Differential distribution and regulation of estrogen receptor-α and -β MRNA within the female rat brain
    • M. Österlund, G.G. Kuiper, J.A. Gustafsson, and Y.L. Hurd Differential distribution and regulation of estrogen receptor-α and -β mRNA within the female rat brain Mol. Brain Res. 54 1 1998 175 180
    • (1998) Mol. Brain Res. , vol.54 , Issue.1 , pp. 175-180
    • Österlund, M.1    Kuiper, G.G.2    Gustafsson, J.A.3    Hurd, Y.L.4
  • 34
    • 0035372636 scopus 로고    scopus 로고
    • Estrogen receptors in the human forebrain and the relation to neuropsychiatric disorders
    • M. Österlund, and Y.L. Hurd Estrogen receptors in the human forebrain and the relation to neuropsychiatric disorders Prog. Neurobiol. 64 3 2001 251 267
    • (2001) Prog. Neurobiol. , vol.64 , Issue.3 , pp. 251-267
    • Österlund, M.1    Hurd, Y.L.2
  • 36
    • 0031932036 scopus 로고    scopus 로고
    • Regulation of serotonin re-uptake transporter mRNA expression by ovarian steroids in rhesus macaques
    • M. Pecins-Thompson, N.A. Brown, and C.L. Bethea Regulation of serotonin re-uptake transporter mRNA expression by ovarian steroids in rhesus macaques Mol. Brain Res. 53 1-2 1998 120 129
    • (1998) Mol. Brain Res. , vol.53 , Issue.12 , pp. 120-129
    • Pecins-Thompson, M.1    Brown, N.A.2    Bethea, C.L.3
  • 37
    • 0015820726 scopus 로고
    • Atlas of estradiol-concentrating cells in the central nervous system of the female rat
    • D. Pfaff, and M. Keiner Atlas of estradiol-concentrating cells in the central nervous system of the female rat J. Comp. Neur. 151 2 1973 121 158
    • (1973) J. Comp. Neur. , vol.151 , Issue.2 , pp. 121-158
    • Pfaff, D.1    Keiner, M.2
  • 38
    • 0017354142 scopus 로고
    • Specific binding sites for oestrogen at the outer surfaces of isolated endometrial cells
    • R. Pietras, and C. Szego Specific binding sites for oestrogen at the outer surfaces of isolated endometrial cells Nature 265 5589 1977 69 72
    • (1977) Nature , vol.265 , Issue.5589 , pp. 69-72
    • Pietras, R.1    Szego, C.2
  • 40
    • 0030980827 scopus 로고    scopus 로고
    • Estrogen effects on cognition in postmenopausal women
    • D.D. Sherwin Estrogen effects on cognition in postmenopausal women Nuerology 48 5 Suppl. 7 1997 S21 S26
    • (1997) Nuerology , vol.48 , Issue.57
    • Sherwin, D.D.1
  • 42
    • 0030727813 scopus 로고    scopus 로고
    • Comparative distribution of estrogen receptor-α and -β MRNA in the rat central nervous system
    • P.J. Shughrue, M.V. Lane, and I. Merchenthaler Comparative distribution of estrogen receptor-α and -β mRNA in the rat central nervous system J. Comp. Neurol. 388 4 1997 507 525
    • (1997) J. Comp. Neurol. , vol.388 , Issue.4 , pp. 507-525
    • Shughrue, P.J.1    Lane, M.V.2    Merchenthaler, I.3
  • 43
    • 0032719205 scopus 로고    scopus 로고
    • Effects of tamoxifen on serotonin transporter and 5-hydroxytryptamine (2A) receptor binding sites and MRNA levels in the brain of ovariectomized rats with or without acute estradiol replacement
    • B.E. Sumner, K.E. Grant, R. Rosie, C. Hegele-Hartung, K.H. Fritzemeier, and G. Fink Effects of tamoxifen on serotonin transporter and 5-hydroxytryptamine (2A) receptor binding sites and MRNA levels in the brain of ovariectomized rats with or without acute estradiol replacement Brain Res. Mol. Brain Res. 73 1-2 1999 119 128
    • (1999) Brain Res. Mol. Brain Res. , vol.73 , Issue.12 , pp. 119-128
    • Sumner, B.E.1    Grant, K.E.2    Rosie, R.3    Hegele-Hartung, C.4    Fritzemeier, K.H.5    Fink, G.6
  • 46
    • 2542540731 scopus 로고    scopus 로고
    • Hormone therapy: Physiological complexity belies therapeutic simplicity
    • J.L. Turgeon, D.P. McDonnell, K.A. Martin, and P.M. Wise Hormone therapy: physiological complexity belies therapeutic simplicity Science 304 5675 2004 1269 1273
    • (2004) Science , vol.304 , Issue.5675 , pp. 1269-1273
    • Turgeon, J.L.1    McDonnell, D.P.2    Martin, K.A.3    Wise, P.M.4
  • 47
    • 0031561119 scopus 로고    scopus 로고
    • Agonistic effect of Tamoxifen is dependent on cell type, ERE-promoter context and estrogen receptor subtype: Functional difference between estrogen receptors α and β
    • T. Watanabe, S. Inoue, S. Ogawa, Y. Ishii, H. Hiroi, K. Ikeda, A. Orimo, and M. Muramatsu Agonistic effect of Tamoxifen is dependent on cell type, ERE-promoter context and estrogen receptor subtype: functional difference between estrogen receptors α and β Biochem. Biophys. Res. Commun. 236 1 1997 140 145
    • (1997) Biochem. Biophys. Res. Commun. , vol.236 , Issue.1 , pp. 140-145
    • Watanabe, T.1    Inoue, S.2    Ogawa, S.3    Ishii, Y.4    Hiroi, H.5    Ikeda, K.6    Orimo, A.7    Muramatsu, M.8
  • 48
    • 0031552508 scopus 로고    scopus 로고
    • 17beta-Estradiol protects against NMDA-induced exitotoxicity by direct inhibition of NMDA receptors
    • C.E. Weaver Jr, M. Park-Chung, T.T. Gibbs, and D.H. Farb 17beta-Estradiol protects against NMDA-induced exitotoxicity by direct inhibition of NMDA receptors Brain Res. 761 2 1997 338 341
    • (1997) Brain Res. , vol.761 , Issue.2 , pp. 338-341
    • Weaver Jr., C.E.1    Park-Chung, M.2    Gibbs, T.T.3    Farb, D.H.4
  • 49
    • 0028851240 scopus 로고
    • Distribution of occupied and unoccupied estrogen receptors in the rat brain: Effects of physiological gonadal steroid exposure
    • H. Yuan, D.A. Bowlby, T.J. Brown, R.B. Hochberg, and N.J. MacLusky Distribution of occupied and unoccupied estrogen receptors in the rat brain: effects of physiological gonadal steroid exposure Endocrinology 136 1 1995 96 105
    • (1995) Endocrinology , vol.136 , Issue.1 , pp. 96-105
    • Yuan, H.1    Bowlby, D.A.2    Brown, T.J.3    Hochberg, R.B.4    MacLusky, N.J.5
  • 51
    • 0022560635 scopus 로고
    • 16 alpha-[125I]iodo-11 beta methoxy-17 beta-estradiol: A radiochemical probe for estrogen-sensitive tissues
    • J.E. Zielinski, H. Yabuki, S.L. Pahuja, J.M. Larner, and R.B. Hochberg 16 alpha-[125I]iodo-11 beta methoxy-17 beta-estradiol: a radiochemical probe for estrogen-sensitive tissues Endocrinology 119 1 1986 130 139
    • (1986) Endocrinology , vol.119 , Issue.1 , pp. 130-139
    • Zielinski, J.E.1    Yabuki, H.2    Pahuja, S.L.3    Larner, J.M.4    Hochberg, R.B.5


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