ACAM2000 clonal Vero cell culture vaccinia virus (New York City Board of Health strain) - A second-generation smallpox vaccine for biological defense

International Journal of Infectious Diseases

Volumn 8, Issue SUPPL. 2, 2004, Pages 31-44

  Monath, Thomas P ^a   Caldwell, Joseph R ^a   Mundt, Wolfgang ^b   Fusco, Joan ^b   Johnson, Casey S ^c   Buller, Mark ^d   Liu, Jian ^a   Gardner, Bridget ^a   Downing, Greg ^a   Blum, Paul S ^a   Kemp, Tracy ^a   Nichols, Richard ^a   Weltzin, Richard ^a  

^a Acambis   (United States)

^b Baxter Bioscience   (United States)

^c PRA HEALTH SCIENCES   (United States)

^d SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SMALLPOX VACCINE; VIRUS VACCINE;

ABDOMINAL PAIN; BIOSAFETY; CLINICAL FEATURE; CLINICAL TRIAL; CONFERENCE PAPER; CONFIDENCE INTERVAL; COUGHING; DIARRHEA; DIZZINESS; DNA SEQUENCE; DRUG EFFICACY; DRUG SCREENING; DRUG SYNTHESIS; ERYTHEMA; EXPERIMENTAL MODEL; FATIGUE; GENETIC ENGINEERING; HEADACHE; HEALTH PROGRAM; HEALTH SURVEY; HUMAN; HYPERTHERMIA; IMMUNE RESPONSE; IMMUNOGENICITY; INFECTION PREVENTION; INFLAMMATION; LYMPHADENOPATHY; MALAISE; MEDICAL SOCIETY; MOLECULAR CLONING; MYALGIA; NAUSEA; NEISSERIA MENINGITIDIS; NONHUMAN; NOSE CONGESTION; PAIN; PHARYNGITIS; PRURITUS; RASH; RIGIDITY; RIGOR; SCORING SYSTEM; SCREENING TEST; SEQUENCE ANALYSIS; SIDE EFFECT; SKIN IRRITATION; SMALLPOX; SURVIVAL; TECHNIQUE; UPPER RESPIRATORY TRACT INFECTION; VACCINIA VIRUS; VERO CELL; VIRUS CULTURE; VIRUS GENOME; VIRUS ISOLATION; VIRUS STRAIN;

EID: 7444242665     PISSN: 12019712     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijid.2004.09.002     Document Type: Conference Paper

References (31)

1. J.M. Lane, F.L. Ruben, J.M. Neff, and J.D. Millar Complications of smallpox vaccination, 1968. national surveillance in the United States New Eng J Med. 281 1969 1201 1208
2. J.M. Lane, F.L. Ruben, J.M. Neff, and J.D. Millar Complications of smallpox vaccination, 1969. results of ten statewide surveys J Infect Dis. 122 1968 303 309
3. D.A. Henderson, T.V. Inglesby, and J.G. Bartlett Smallpox as a biological weapon: medical and public health management J Am Med Assoc. 281 1999 2127 2137
4. K. Alibek Biohazard. 1999 Random House NY
5. S.E. Frey, F.K. Newman, and J. Cruz Dose-related effects of smallpox vaccine N Engl J Med. 346 2002 1275 1280
6. S.E. Frey, R.B. Couch, and C.O. Tackett Clinical responses to undiluted and diluted smallpox vaccine N Engl J Med. 346 2002 1265 1274
7. M. Sugimoto, A. Yasuda, K. Miki, M. Morita, K. Suzuki, N. Uchida, and S. Hashizume Gene structure of low-neurovirulent vaccinia virus LC16m0, LC16m8, and their Lister original (LO) strains Microbiol Immunol. 29 1985 421 428
8. A.C. Hekker, J.M. Bos, N.K. Rai, J. Keja, G. Cuboni, B. Emmet, and J. Djalins Large-scale use of freeze-dried smallpox vaccine prepared in primary cultures of rabbit kidney cells Bull WHO 54 1976 279 284
9. D.J. McCLain, S. Harrison, C.L. Yeager, J. Cruz, F.A. Ennis, P. Gibbs, E.S. Wright, P.J. Summers, J.D. Arthur, and J.A. Graham Immunologic responses to vaccinia vaccines administered by different peripheral routes J Infect Dis. 175 1997 756 763
10. R. Weltzin, J. Liu, K.V. Pugachev, G.A. Myers, B. Coughlin, P.S. Blum, R. Nichols, C. Johnson, J. Cruz, J.S. Kennedy, F.A. Ennis, and T.P. Monath Clonal vaccinia virus grown in cell culture as a new smallpox vaccine Nat Med. 9 2003 1125 1130
11. J.D. Gangemi, and D.G. Sharp Particle heterogeneity in vaccinia virus populations during passage Virology. 85 1978 262 270
12. L. Kutinova, V. Ludvikova, V. Simonova, M. Otavova, J. Krystofova, P. Hainz, M. Press, D. Kunke, and V. Vonka Search for optimal parent for recombinant vaccinia virus vaccines. Study of three vaccinia virus vaccinial strains and several virus lines derived from them Vaccine 13 1995 487 493
13. L. Kutinova, V. Ludvikova, J. Krystofova, Otavova, V. Simonova, S. Nemeckova, P. Hainz, and V. Vonka Influence of the parental virus strain on the virulence and immunogenicity of recombinant vaccinia viruses expressing HBV preS2-S protein or VZV glycoprotein I Vaccine 14 1996 1045 1052
14. G. McFadden, and S. Dales Biogenesis of poxviruses: mirror image deletions in vaccinia virus DNA Cell. 18 1979 101 108
15. B. Moss, E. Winters, and J.A. Cooper Deletion of a 9,000-base pair segment of the vaccinia virus genome that encodes nonessential polypeptides J Virol. 40 1981 387 395
16. D. Panacali, S.W. Davis, S.R. Mercer, and E. Paoleti Two major DNA variants present in serially propagated stocks of the WR strain of vaccinia virus J Virol. 37 1981 1000 1010
17. Paez E, Dallo S, Esteban M. Generation of a dominant 8-MDa deletion at the left terminus of vaccinia virus DNA. Proc Natl Acad Sci USA 82:3365-9.
18. S. Dallo, and M. Esteban Isolation and characterization of attenuated mutants of vaccinia virus Virology 159 1987 408 422
19. W. Ehrengut, D.E. Sarateanu, U. Alswede, A. Habib, and G. Tetzlaff Vaccinia virus variants as presumable cause of vaccinial complications Arch Virol. 48 1975 229 238
20. W. Ehrengut, and D.E. Sarateanu Differences in the quality of vaccinia viruses with normal and abnormal post-vaccination course (with neurological complications) Dtsch Med Wochenschr. 100 1975 1457 1461
21. I.S. Vilesova, E.B. Gurvich, S.G. Dzagurov, L.V. Grigor'eva, and H. Abel Changes in the properties of the vaccinia virus isolated in postvaccinal encephalitis Vopr Virusol. 30 1985 477 482
22. S.S. Marennikova, K.L. Chimishkyan, N.N. Maltseva, E.M. Shelukhina, and V.V. Fedorov B. Gusic Proceedings of the Symposium on Smallpox 2 & 3 September 1969 1969 Yugoslav Academy of Sciences and Arts Zagreb 65 79
23. S.S. Marennikova International Symposium on Smallpox Vaccine Bilthoven, the Netherlands, 11-13 October 1972 1973 Karger Basel 253 260
24. M.F. Polak, Beunders BJW, A.R. Werff, E.W. Van der Sanders, J.N. Klaveren, and L.M. Van Brans A comparative study of clinical reactions observed after application of several smallpox vaccines in primary vaccination of young adults Bull WHO 29 1963 311 322
25. E.B. Gurvich, and I.S. Vilesova Vaccinia virus in postvaccinal encephalitis Acta Virol. 27 1983 154 159
26. J.J. Angulo, E. Pimenta-de-Campos, and L.F. de Salles-Gomez Postvaccinal meningoencephalitis J Am Med Assn. 187 1964 151 153
27. E. de Vries Postvaccinal perivenous encephalitis 1960 Elsevier Amsterdam
28. M. Morita, M. Arita, T. Komatsu, H. Amano, and S. Hashizume A comparison of neurovirulence of vaccinia virus by intrathalamic and/or intracisternal inoculations into cynomolgus monkeys Microbiol Immunol. 21 1977 417 418
29. Artenstein AW, Johnson C, Marbury T, Morrison D, Blum PS, Kemp T, Nichols R, Balser PB, Currie M, Monath TP. A novel, cell culture-derived smallpox vaccine in vaccinia-naïve adults. Vaccine (submitted).
30. R.E. Eckart, S.S. Love, J.E. Atwood, M.K. Arness, D.C. Cassimatis, C.L. Campbell, S.Y. Boyd, J.G. Murphy, D.L. Swerdlow, L.C. Collins, J.R. Riddle, D.N. Tornberg, J.D. Grabenstein, and R.J. Engler Incidence and Follow-Up of Inflammatory Cardiac Complications After Smallpox Vaccinations J Am Coll Cardiol. 44 2004 201 205
31. Centers for Disease Control Update: cardiac and other adverse events following civilian smallpox vaccination - United States MMWR Morb Mortal Wkly Rep. 52 2003 639 642