Cytotoxicity suppression and cellular uptake enhancement of surface modified magnetic nanoparticles

Biomaterials

Volumn 26, Issue 13, 2005, Pages 1565-1573

  Gupta, Ajay Kumar ^a,c   Gupta, Mona ^b  

^a Nat Rsrc Inst Univ G   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c SOUTHERN GENERAL HOSPITAL   (United Kingdom)

Author keywords

Cell adhesion; Cytotoxicity; Drug delivery; Magnetic nanoparticle; Surface modification; TEM

Indexed keywords

BIOMECHANICS; CYTOLOGY; DERMATOLOGY; MAGNETIC MATERIALS; MORPHOLOGY; NANOSTRUCTURED MATERIALS; TOXICITY; TRANSMISSION ELECTRON MICROSCOPY;

CELL ADHESION; CYTOSKELETON; CYTOTOXICITY; DERMAL FIBROBLASTS;

CELL CULTURE;

IRON OXIDE; NANOPARTICLE; PULLULAN; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE;

ARTICLE; CELL ADHESION; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; CYTOSKELETON; CYTOTOXICITY; DRUG DELIVERY SYSTEM; ENDOCYTOSIS; FIBROBLAST; HUMAN; HUMAN CELL; HYDROPHILICITY; INTERNALIZATION; INTRACELLULAR TRANSPORT; MAGNETISM; PARTICLE SIZE; PRIORITY JOURNAL; SURFACE PROPERTY; TRANSMISSION ELECTRON MICROSCOPY;

APOPTOSIS; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; COATED MATERIALS, BIOCOMPATIBLE; CYTOSKELETON; DRUG IMPLANTS; ENDOCYTOSIS; FERRIC COMPOUNDS; FIBROBLASTS; GLUCANS; HUMANS; MAGNETICS; MATERIALS TESTING; NANOTUBES;

EID: 7444234174     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2004.05.022     Document Type: Article

References (25)

1. Weissleder R., Bogdanov A., Neuwelt E.A., Papisov M. Long circulating iron oxides for MR imaging. Adv Drug Del Rev. 16:1995;321-334
2. Berry C.C., Curtis A.S.G. Functionalisation of magnetic nanoparticles for applications in biomedicine. J Phys D: Appl Phys. 36:2003;R198-R206
3. Chouly C., Pouliquen D., Lucet I., Jeune J.J., Jallet P. Development of superparamagentic nanoparticles for MRI. effect of particle size, charge and surface nature on biodistribution J Microencapsul. 3:1996;245-255
4. Moghimi S.M., Hunter A.C., Murray J.C. Long circulating and target specific nanoparticles. theory to practise Pharm Rev. 53:2001;283-318
5. Stolnik S., Illum L., Davis S.S. Long circulating microparticulate drug carriers. Adv Drug Del Rev. 16:1995;195-214
6. Gupta A.K., Curtis A.S.G. Lactoferrin and ceruloplasmin derivatized superpara-magnetic iron oxide nanoparticles. preparation, characterization and their influence on human dermal fibroblasts in culture Proc Ann Symp Control Rel Bioact Mater. 30:2003;788
7. Hallab N.J., Bundy K.J., O'Connor K., Clark R., Moses R.L. Cell adhesion to biomaterials. correlations between surface charge, surface roughness, adsorbed protein and cell morphology J. Long-Term Eff Med Implants. 5(3):1995;209-231
8. Absolom D.R., Zingg W., Neumann A.W. Protein adsorption to polymer particles. role of surface properties J Biomed Mater Res. 21:1987;161-171
9. Haas T.A., Plow E.F. Integrin-ligand interactions. a year in review Curr Opin Cell Biol. 6:1994;656-662
10. Lyman S., Gilmore A., Burridge K., Gidwitz S. White GC 2nd integrin-mediated activation of focal adhesion kinase is independent of focal adhesion formation or integrin activation. Studies with activated and inhibitory beta3 cytoplasmic domain mutants. J Biol Chem. 272(36):1997;22538-22547
11. Gupta A.K., Gupta M., Yarwood S.J., Curtis A.S.G. Effect of cellular uptake of gelatin nanoparticles on adhesion, morphology and cytoskeleton organisation of human fibroblasts. J Control Rel. 95(2):2004;197-207
12. Gupta A.K., Curtis A.S.G. Lactoferrin and ceruloplasmin derivatized superparamagnetic iron oxide nanoparticles for targeting cell surface receptors. Biomaterials. 25(15):2004;3029-3040
13. Gagesu R., Gruenberg J., Smyte E. Membrane dynamics in endocytosis. structure-function relationship Traffic. 1:2000;84-88
14. Yang Y., Bauer C., Strasser G., Wollman R., Julien J-.P., Fuchs E. Integrators of the cytoskeleton that stabilize microtubules. Cell. 98:1999;229-238
15. Dewar H., Warren D.T., Gardiner F.C., Gourlay C.G., Satish N., Richardson M.R., Andrews P.D., Ayscough K.R. Novel proteins linking the actin cytoskeleton to the endocytic machinery in Saccharomyces cerevisiae. Mol Biol Cell. 13(10):2002;3646-3661
16. Yuen S. Pullulan and its applications. Process Biochem. 9(9):1974;7-9
17. Kaneo Y., Tanaka T., Nakano T., Yamaguchi Y. Evidence for receptor-mediated hepatic uptake of pullulan in rats. J Control Rel. 70(3):2001;365-373
18. Gupta A.K., Wells S. Surface modified superparamagnetic nanoparticles for drug delivery. preparation, characterisation and cytotoxicity studies IEEE Trans Nanobiosci. 3(1):2003;66-73
19. Adams P.E. Determining iron content in foods by spectrophotometry. J Chem Ed. 72:1995;649-651
20. Gupta A.K., Curtis A.S.G. Surface modified superparamagnetic nanoparticles for drug delivery. interaction studies with human fibroblasts in culture J Mater Sci: Mater Med. 15:2004;493-496
21. Mosmann T. Rapid colorimetric assay for cellular growth and survival. application to proliferation and cytotoxic assay J Immunol Methods. 95:1993;55-63
22. Berry C.C., Wells S., Charles S., Curtis A.S.G. Dextran and albumin derivatised iron oxide nanoparticles. influence on fibroblasts in vitro Biomaterials. 24(25):2003;4551-4557
23. Gupta A.K., Berry C., Gupta M., Curtis A. Receptor-mediated Targeting of magnetic nanoparticles using insulin as a surface ligand to prevent endocytosis. IEEE Trans Nanobiosci. 2(4):2003;256-261
24. Riezman H., Woodman P.G., van Meer G., Marsh M. Molecular mechanisms of endocytosis. Cell. 91:1997;731-738
25. Xi K., Tabata Y., Uno K., Yoshimoto M., Kishida T., Sokawa Y., Ikada Y. Liver Targeting of Interferon Through Pullulan Conjugation. Pharm Res. 13(12):1996;1846-1850