Microvascular Po2 during extreme hemodilution with hemoglobin site specifically PEGylated at Cys-93(β) in hamster window chamber

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 287, Issue 4 56-4, 2004, Pages

  Cabrales, Pedro ^a   Kanika, Nirmala Devi ^b   Manjula, Belur N ^b   Tsai, Amy G ^a   Acharya, Seetharama A ^b   Intaglietta, Marcos ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Blood substitutes; Functional capillary density; Hemoglobin cooperativity; Oxygen carrying capacity; Surface modified hemoglobin; Tissue oxygen delivery

Indexed keywords

CYSTEINE; DEXTRAN 70; HEMOGLOBIN; MACROGOL; OXYGEN; PEGYLATED HEMOGLOBIN; UNCLASSIFIED DRUG; MACROGOL DERIVATIVE; PEG HEMOGLOBIN; PEG-HEMOGLOBIN;

ALLOSTERISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING SITE; BLOOD RHEOLOGY; BLOOD VOLUME; CONTROLLED STUDY; DRUG CONJUGATION; HAMSTER; HEART INDEX; HEMATOCRIT; HEMODILUTION; HEMODYNAMIC PARAMETERS; HEMOGLOBIN DETERMINATION; MALE; MICROVASCULATURE; NONHUMAN; OXYGEN CONSUMPTION; OXYGEN DISSOCIATION CURVE; OXYGEN SATURATION; OXYGEN TISSUE LEVEL; OXYGEN TRANSPORT; PRIORITY JOURNAL; PROTEIN BINDING; SHEAR STRESS; ANIMAL; BLOOD; BLOOD PRESSURE; BLOOD VISCOSITY; DRUG EFFECT; HEART RATE; HYPOVOLEMIA; METABOLISM; MICROCIRCULATION; PATHOPHYSIOLOGY; PRESSURE; SYRIAN HAMSTER;

ANIMALS; BLOOD PRESSURE; BLOOD VISCOSITY; CRICETINAE; CYSTEINE; HEART RATE; HEMODILUTION; HEMOGLOBINS; HYPOVOLEMIA; MALE; MESOCRICETUS; MICROCIRCULATION; OXYGEN; PARTIAL PRESSURE; POLYETHYLENE GLYCOLS;

EID: 7444231150     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.00146.2004     Document Type: Article

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