Expression of embryonic stem cell markers in cultured JKT-1, a cell line derived from a human seminoma

International Journal of Andrology

Volumn 33, Issue 1, 2010, Pages 54-63

  Bouskine, Adil ^a,b   Vega, Aurélie ^a,b   Nebout, Marielle ^a,b   Benahmed, Mohamed ^a,b   Fénichel, Patrick ^a,b  

^a CENTRE MÉDITERRANÉEN DE MÉDECINE MOLÉCULAIRE C3M   (France)

^b UNIVERSITY HOSPITAL OF NICE   (France)

Author keywords

Embryonic stem cell; Human seminoma cell line; JKT 1; Pluripotency markers; Testicular germ cell tumour

Indexed keywords

ALKALINE PHOSPHATASE; CHORIONIC GONADOTROPIN BETA SUBUNIT; HIWI PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR AP 2; TRANSCRIPTION FACTOR NANOG; TUMOR MARKER; UNCLASSIFIED DRUG;

ARTICLE; EMBRYONIC STEM CELL; GERM CELL TUMOR; HUMAN; HUMAN CELL; JKT 1 CELL; MALE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEMINOMA; TESTIS TUMOR; WESTERN BLOTTING;

ADULT; CARCINOMA, EMBRYONAL; CELL LINE; EMBRYONIC STEM CELLS; FEMALE; GERM CELLS; HUMANS; MALE; NEOPLASMS, GERM CELL AND EMBRYONAL; PREGNANCY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEMINOMA; TESTICULAR NEOPLASMS; TESTIS;

EID: 74349130363     PISSN: 01056263     EISSN: 13652605     Source Type: Journal    
DOI: 10.1111/j.1365-2605.2009.00950.x     Document Type: Article

References (45)

1. Andrews, P. W., Matin, M. M., Bahrami, A. R., Damjanov, I., Gokhale, P. Draper, J. S. (2005) Embryonic stem (ES) cells and embryonal carcinoma (EC) cells: opposite sides of the same coin. Biochemical Society Transactions 33, 1526 1530.
2. Beger, M., Butz, K., Denk, C., Williams, T., Hurst, H. C. Hoppe-Seyler, F. (2001) Expression pattern of AP-2 transcription factors in cervical cancer cells and analysis of their influence on human papillomavirus oncogene transcription. Journal of Molecular Medicine 79, 314 320.
3. Bouskine, A., Nebout, M., Mograbi, B., Brucker-Davis, F., Roger, C. Fenichel, P. (2008) Estrogens promote human testicular germ cell cancer through a membrane-mediated activation of extracellular regulated kinase and protein kinase A. Endocrinology 149, 565 573.
4. Chaganti, R. S. Houldsworth, J. (2000) Genetics and biology of adult human male germ cell tumors. Cancer Research 60, 1475 1482. (Pubitemid 30183409)
5. Cheng, C. J., Wu, Y. C., Shu, J. A., Ling, T. Y., Kuo, H. C., Wu, J. Y., Chang, E. E., Chang, S. C. Huang, Y. H. (2007) Aberrant expression and distribution of the OCT-4 transcription factor in seminomas. Journal of Biomedical Science 14, 797 807.
6. Eckert, D., Nettersheim, D., Heukamp, L. C., Kitazawa, S., Biermann, K. Schorle, H. (2008) TCam-2 but not JKT-1 cells resemble seminoma in cell culture. Cell and Tissue Research 331, 529 538.
7. Ezeh, U. I., Turek, P. J., Reijo, R. A. Clark, A. T. (2005) Human embryonic stem cell genes OCT4, NANOG, STELLAR, and GDF3 are expressed in both seminoma and breast carcinoma. Cancer 104, 2255 2265.
8. Fogh, J. (1978) Cultivation, characterization, and identification of human tumor cells with emphasis on kidney, testis, and bladder tumors. National Cancer Institute Monograph 49, 5 9.
9. Fujii, T., Otsuki, T., Moriya, T., Sakaguchi, H., Kurebayashi, J., Yata, K. et al. (2002) Effect of hypoxia on human seminoma cells. International Journal of Oncology 20, 955 962.
10. Goddard, N. C., McIntyre, A., Summersgill, B., Gilbert, D., Kitazawa, S. Shipley, J. (2008) KIT and RAS signalling pathways in testicular germ cell tumours: new data and a review of the literature. International Journal of Andrology 30, 337 348.
11. Hamilton-Dutoit, S. J., Lou, H. Pallesen, G. (1990) The expression of placental alkaline phosphatase (PLAP) and PLAP-like enzymes in normal and neoplastic human tissues. An immunohistological survey using monoclonal antibodies. Apmis 98, 797 811.
12. Hart, A. H., Hartley, L., Parker, K., Ibrahim, M., Looijenga, L. H., Pauchnik, M., Chow, C. W. Robb, L. (2005) The pluripotency homeobox gene NANOG is expressed in human germ cell tumors. Cancer 104, 2092 2098.
13. Hatakeyama, S., Ohyama, C., Minagawa, S., Inoue, T., Kakinuma, H., Kyan, A. et al. (2004) Functional correlation of trophinin expression with the malignancy of testicular germ cell tumor. Cancer Research 64, 4257 4262.
14. Hoei-Hansen, C. E., Nielsen, J. E., Almstrup, K., Sonne, S. B., Graem, N., Skakkebaek, N. E., Leffers, H. Rajpert-De Meyts, E. (2004) Transcription factor AP-2gamma is a developmentally regulated marker of testicular carcinoma in situ and germ cell tumors. Clinical Cancer Research 10, 8521 8530.
15. Hoei-Hansen, C. E., Almstrup, K., Nielsen, J. E., Brask Sonne, S., Graem, N., Skakkebaek, N. E., Leffers, H. Rajpert-De Meyts, E. (2005) Stem cell pluripotency factor NANOG is expressed in human fetal gonocytes, testicular carcinoma in situ and germ cell tumours. Histopathology 47, 48 56.
16. Huang, S., Jean, D., Luca, M., Tainsky, M. A. Bar-Eli, M. (1998) Loss of AP-2 results in downregulation of c-KIT and enhancement of melanoma tumorigenicity and metastasis. EMBO Journal 17, 4358 4369. (Pubitemid 28362626)
17. Iczkowski, K. A., Butler, S. L., Shanks, J. H., Hossain, D., Schall, A., Meiers, I., Zhou, M., Torkko, K. C., Kim, S. J. MacLennan, G. T. (2008) Trials of new germ cell immunohistochemical stains in 93 extragonadal and metastatic germ cell tumors. Human Pathology 39, 275 281.
18. Jo, Y., Kinugawa, K., Matsuki, T., Morioka, M. Tanaka, H. (1999) Analysis of the biological properties and use of comparative genomic hybridization to locate chromosomal aberrations in the human testicular seminoma cell line JKT-1 and its highly metastatic cell line JKT-HM. BJU International 83, 469 475.
19. de Jong, J., Stoop, H., Gillis, A. J., van Gurp, R. J., van Drunen, E., Beverloo, H. B. et al. (2007a) JKT-1 is not a human seminoma cell line. International Journal of Andrology 30, 350 365.
20. de Jong, J., Weeda, S., Gillis, A. J., Oosterhuis, J. W. Looijenga, L. H. (2007b) Differential methylation of the OCT3/4 upstream region in primary human testicular germ cell tumors. Oncology Reports 18, 127 132.
21. de Jong, J., Stoop, H., Gillis, A. J., Hersmus, R., van Gurp, R. J., van de Geijn, G. J. et al. (2008) Further characterization of the first seminoma cell line TCam-2. Genes, Chromosomes and Cancer 47, 185 196.
22. Kinugawa, K., Hyodo, F., Matsuki, T., Jo, Y., Furukawa, Y., Ueki, A. Tanaka, H. (1998) Establishment and characterization of a new human testicular seminoma cell line, JKT-1. International Journal of Urology 5, 282 287.
23. Kitazawa, S., Takenaka, A., Kondo, T., Mizoguchi, A. Kitazawa, R. (2006) Protruding disordered loop of gC1qR is specifically exposed and related to antiapoptotic property in germ cell lineage. Histochemistry and Cell Biology 126, 665 677.
24. Kobayashi, T., Fujii, T., Jo, Y., Kinugawa, K. Fujisawa, M. (2004) Possible mechanism responsible for the acquisition of resistance to cis-diamminedichloroplatinum (II) by cultured human testicular seminoma cells. Journal of Urology 171, 1929 1933.
25. Korkola, J. E., Houldsworth, J., Chadalavada, R. S., Olshen, A. B., Dobrzynski, D., Reuter, V. E., Bosl, G. J. Chaganti, R. S. (2006) Down-regulation of stem cell genes, including those in a 200-kb gene cluster at 12p13.31, is associated with in vivo differentiation of human male germ cell tumors. Cancer Research 66, 820 827.
26. Koshida, K., Konaka, H., Kato, H., Miyagi, T., Egawa, M., Uchibayashi, T. Namiki, M. (2000) Correlation between expression of metastasis-related genes and lymph node metastasis in testicular cancer. Hinyokika Kiyo 46, 775 781.
27. Leroy, X., Augusto, D., Leteurtre, E. Gosselin, B. (2002) CD30 and CD117 (c-kit) used in combination are useful for distinguishing embryonal carcinoma from seminoma. Journal of Histochemistry and Cytochemistry 50, 283 285.
28. Looijenga, L. H., Hersmus, R., Gillis, A. J., Pfundt, R., Stoop, H. J., van Gurp, R. J. et al. (2006) Genomic and expression profiling of human spermatocytic seminomas: primary spermatocyte as tumorigenic precursor and DMRT1 as candidate chromosome 9 gene. Cancer Research 66, 290 302.
29. Mizuno, Y., Gotoh, A., Kamidono, S. Kitazawa, S. (1993) Establishment and characterization of a new human testicular germ cell tumor cell line (TCam-2). Nippon Hinyokika Gakkai Zasshi 84, 1211 1218.
30. Mueller, T., Mueller, L. P., Luetzkendorf, J., Voigt, W., Simon, H. Schmoll, H. J. (2006) Loss of Oct-3/4 expression in embryonal carcinoma cells is associated with induction of cisplatin resistance. Tumour Biology 27, 71 83.
31. Olie, R. A., Boersma, A. W., Dekker, M. C., Nooter, K., Looijenga, L. H. Oosterhuis, J. W. (1996) Apoptosis of human seminoma cells upon disruption of their microenvironment. British Journal of Cancer 73, 1031 1036.
32. Oosterhuis, J. W. Looijenga, L. H. (2005) Testicular germ-cell tumours in a broader perspective. Nature Review Cancer 5, 210 222.
33. Pauls, K., Jager, R., Weber, S., Wardelmann, E., Koch, A., Buttner, R. Schorle, H. (2005) Transcription factor AP-2gamma, a novel marker of gonocytes and seminomatous germ cell tumors. International Journal of Cancer 115, 470 477.
34. Qiao, D., Zeeman, A. M., Deng, W., Looijenga, L. H. Lin, H. (2002) Molecular characterization of hiwi, a human member of the piwi gene family whose overexpression is correlated to seminomas. Oncogene 21, 3988 3999.
35. Rajpert-De Meyts, E. (2006) Developmental model for the pathogenesis of testicular carcinoma in situ: genetic and environmental aspects. Human Reproduction Update 12, 303 323.
36. Roger, C., Mograbi, B., Chevallier, D., Michiels, J. F., Tanaka, H., Segretain, D., Pointis, G. Fenichel, P. (2004) Disrupted traffic of connexin 43 in human testicular seminoma cells: overexpression of Cx43 induces membrane location and cell proliferation decrease. Journal of Pathology 202, 241 246.
37. Roger, C., Lambard, S., Bouskine, A., Mograbi, B., Chevallier, D., Nebout, M., Pointis, G., Carreau, S. Fenichel, P. (2005) Estrogen-induced growth inhibition of human seminoma cells expressing estrogen receptor beta and aromatase. Journal of Molecular Endocrinology 35, 191 199.
38. Santagata, S., Ligon, K. L. Hornick, J. L. (2007) Embryonic stem cell transcription factor signatures in the diagnosis of primary and metastatic germ cell tumors. American Journal of Surgical Pathology 31, 836 845.
39. Shiraishi, T., Yoshida, T., Nakata, S., Horinaka, M., Wakada, M., Mizutani, Y., Miki, T. Sakai, T. (2005) Differential response at the hGABP/E4TF1 site of retinoblastoma gene promoter in human testicular seminoma cells. Oncology Reports 13, 871 874.
40. Skakkebaek, N. E. (1972) Possible carcinoma-in-situ of the testis. Lancet 2, 516 517.
41. Skakkebaek, N. E., Berthelsen, J. G., Giwercman, A. Muller, J. (1987) Carcinoma-in-situ of the testis: possible origin from gonocytes and precursor of all types of germ cell tumours except spermatocytoma. International Journal of Andrology 10, 19 28.
42. Smith, P. K., Krohn, R. I., Hermanson, G. T., Mallia, A. K., Provenzano, M. D., Fujimoto, E. K. et al. (1985) Measurement of protein using bicinchoninic acid. Annal Biochem 163, 279 280.
43. Tai, M. H., Chang, C. C., Kiupel, M., Webster, J. D., Olson, L. K. Trosko, J. E. (2005) Oct4 expression in adult human stem cells: evidence in support of the stem cell theory of carcinogenesis. Carcinogenesis 26, 495 502.
44. Teshima, S., Shimosato, Y., Hirohashi, S., Tome, Y., Hayashi, I., Kanazawa, H. Kakizoe, T. (1988) Four new human germ cell tumor cell lines. Laboratory Investigation 59, 328 336.
45. Uchida, T., Shimoda, T., Miyata, H., Shikata, T., Iino, S., Suzuki, H., Oda, T., Hirano, K. Sugiura, M. (1981) Immunoperoxidase study of alkaline phosphatase in testicular tumor. Cancer 48, 1455 1462.