Lipoprotein lipase and endothelial lipase in human testis and in germ cell neoplasms

International Journal of Andrology

Volumn 33, Issue 1, 2010, Pages

  Nielsen, J E ^a   Lindegaard, M L ^a   Friis Hansen, L ^a   Almstrup, K ^a   Leffers, H ^a   Nielsen, L B ^a,b   Rajpert De Meyts, E ^a  

^a Rigshospitalet   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Carcinoma in situ testis; Endothelial lipase; Lipoprotein lipase; Testicular cancer; Testicular germ cell tumours

Indexed keywords

CHOLESTEROL; COMPLEMENTARY DNA; ENDOTHELIAL LIPASE; LIPID; LIPOPROTEIN LIPASE; MESSENGER RNA; OCTAMER TRANSCRIPTION FACTOR 4; TESTOSTERONE; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

ARTICLE; CARCINOMA IN SITU; CONTROLLED STUDY; DIAGNOSTIC VALUE; ENZYME LOCALIZATION; GENE EXPRESSION; GERM CELL TUMOR; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; LEYDIG CELL; MALE; ORCHIECTOMY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SERTOLI CELL; STEROIDOGENESIS; TESTIS; TESTIS CANCER; TESTIS TUMOR;

CARCINOMA, EMBRYONAL; ENDOTHELIUM; GERM CELLS; HUMANS; LEYDIG CELLS; LIPASE; LIPOPROTEIN LIPASE; MALE; NEOPLASMS, GERM CELL AND EMBRYONAL; NITRIC OXIDE SYNTHASE TYPE III; RNA, MESSENGER; SEMINIFEROUS TUBULES; SEMINOMA; SERTOLI CELLS; SPERMATOCYTES; TESTICULAR NEOPLASMS; TESTIS;

EID: 74349124125     PISSN: 01056263     EISSN: 13652605     Source Type: Journal    
DOI: 10.1111/j.1365-2605.2009.00988.x     Document Type: Article

References (35)

1. Almstrup, K., Hoei-Hansen, C. E., Wirkner, U., Blake, J., Schwager, C., Ansorge, W., Nielsen, J. E., Skakkebaek, N. E., Rajpert-De Meyts, E. Leffers, H. (2004) Embryonic stem cell-like features of testicular carcinoma in situ revealed by genome- wide gene expression profiling. Cancer Research 64, 4736 4743.
2. Andersen, A. G., Jensen, T. K., Carlsen, E., Jørgensen, N., Andersson, A. M., Krarup, T., Keiding, N. Skakkebæk, N. E. (2000) High frequency of sub-optimal semen quality in an unselected population of young men. Human Reproduction 15, 366 372.
3. Andrews, P. W., Casper, J., Damjanov, I., Duggan-Keen, M., Giwercman, A., Hata, J. et al. (1996) Comparative analysis of cell surface antigens expressed by cell lines derived from human germ cell tumours. International Journal of Cancer 66, 806 816.
4. Arenas, M. I., Lobo, M. V. T., Caso, E., Huerta, L., Paniagua, R. Martín-Hidalgo, M. A. (2004) Normal and pathological human testes express hormone-sensitive lipase and the lipid receptors CLA-1/SR-B1 and CD36. Human Pathology 35, 34 42.
5. Bartels, E. D., Nielsen, J. E., Lindegaard, M. L. S., Hulten, L. M., Scroeder, T. V. Nielsen, L. B. (2007) Endothelial lipase is highly expressed in macrophages in advanced human atherosclerotic lesions. Atherosclerosis 195, e42 e49.
6. Braun, J. E. Severson, D. L. (1992) Regulation of the synthesis, processing and translocation of lipoprotein lipase. Biochemical Journal 287, 337 347.
7. Broedl, U. C., Maugeais, C., Marchadier, D., Glick, J. M. Rader, D. J. (2003) Effects of nonlipolytic ligand function of endothelial lipase on high density lipoprotein metabolism in vivo. Journal of Biological Chemistry 278, 40688 40693.
8. Broedl, U. C., Jin, W., Marchadier, D., Secreto, A. Radar, D. J. (2005) Tissue-specific expression pattern of human endothelial lipase in transgenic mice. Atherosclerosis 181, 271 274.
9. Chung, K. W. Hamilton, J. B. (1975) Testicular lipids in mice with testicular feminization. Cell and Tissue Research 27, 69 80.
10. Coalson, R. E. (1991) Staining methods for cell types in endocrine glands. In : Staining Procedures (ed. G. Clark pp. 228 229. Williams and Wilkins, Baltimore, MD.
11. Eisenberg, S., Sehayek, E., Olivecrona, T. Vlodavsky, I. (1992) Lipoprotein lipase enhances binding of lipoproteins to heparan sulfate on cell surfaces and extracellular matrix. Journal of Clinical Investigation 90, 2013 2021.
12. Fuki, I. V., Blanchard, N., Jin, W., Marchadier, D. H., Millar, J. S., Glick, J. M. Rader, D. J. (2003) Endogenously produced endothelial lipase enhances binding and cellular processing of plasma lipoproteins via heparan sulfate proteoglycan-mediated pathway. Journal of Biological Chemistry 278, 34331 34338.
13. Giwercman, A., Cantell, L. Marks, A. (1991) Placental-like alkaline phosphatase as a marker of carcinoma-in-situ of the testis: comparison with monoclonal antibodies M2A and 43-9F. Acta Pathologica, Microbiologica et Immunologica Scandinavica 99, 586 594.
14. Hirata, K., Dichek, H. L., Cioffi, J. A., Choi, S. Y., Leeper, N. J., Quintana, L., Kronmal, G. S., Cooper, A. D. Quertermous, T. (1999) Cloning of a unique lipase from endothelial cells extends the lipase gene family. Journal of Biological Chemistry 274, 14170 14175.
15. Hoei-Hansen, C. E., Nielsen, J. E., Almstrup, K., Hansen, M. A., Skakkebaek, N. E., Rajpert-De Meyts, E. Leffers, H. (2004a) Identification of genes differentially expressed in testes containing carcinoma in situ. Molecular Human Reproduction 10, 423 431.
16. Hoei-Hansen, C. E., Nielsen, J. E., Almstrup, K., Sonne, S. B., Graem, N., Skakkebaek, N. E., Leffers, H. Rajpert-De Meyts, E. (2004b) Transcription factor AP-2γ is a developmentally regulated marker of testicular carcinoma in situ and germ cell tumors. Clinical Cancer Research 10, 8521 8530.
17. Ishida, T., Zheng, Z., Dichek, H. L., Wang, H., Moreno, I., Yang, E. et al. (2004) Molecular cloning of nonsecreted endothelial cell-derived lipase isoforms. Genomics 83, 24 33.
18. Jaye, M., Lynch, K. J., Krawiec, J., Marchadier, D., Maugeais, C., Doan, K., South, V., Amin, D., Perrone, M. Rader, D. J. (1999) A novel endothelial-derived lipase that modulates HDL metabolism. Nature Genetics 21, 424 428.
19. Lindegaard, M. L. S., Olivecrona, G., Christoffersen, C., Kratky, D., Hannibal, J., Petersen, B. L., Zencher, R., Damm, P. Nielsen, L. B. (2005a) Endothelial and lipoprotein lipases in human and mouse placenta. Journal of Lipid Research 46, 2339 2346.
20. Lindegaard, M. L. S., Nielsen, J. E., Hannibal, J. Nielsen, L. B. (2005b) Expression of the endothelial lipase gene in murine embryos and reproductive organs. Journal of Lipid Research 46, 439 444.
21. Looijenga, L. H., Stoop, H., de Leeuw, H. P., de Gouveia Brazao, C. A., Gillis, A. J., van Roozendaal, K. E. et al. (2003) POU5F1 (OCT3/4) identifies cells with pluripotent potential in human cell tumors. Cancer Research 63, 2244 2250.
22. Magnusson-Olsson, A. L., Lager, S., Jacobsson, B., Jansson, T. Powell, T. L. (2007) Effect of maternal triglycerides and free fatty acids on placental LPL in cultured primary trophoblast cells and in a case of maternal LPL deficiency. American Journal of Physiology, Endocrinology and Metabolism 293, E24 E30.
23. McCoy, M. G., Sun, G. S., Marchadier, D., Maugeais, C., Glick, J. M. Radar, D. J. (2002) Characterization of the lipolytic activity of endothelial lipase. Journal of Lipid Research 43, 921 929.
24. Mead, J. R., Irvine, S. A. Ramji, D. P. (2002) Lipoprotein lipase: structure, function, regulation and role in disease. Journal of Molecular Medicine 80, 753 769.
25. Merkel, M., Kato, Y., Radner, H., Cho, I. S., Ramasamy, R., Brunzell, J. D., Goldberg, I. J. Breslow, J. L. (1998) Catalytically inactive lipoprotein lipase expression in muscle of transgenic mice increases very low density lipoprotein uptake: Direct evidence that lipoprotein lipase bridging occurs in vivo. Proceedings of the National Academy of Sciences of the United States of America 95, 13841 13846.
26. Merkel, M., Heeren, J., Dudeck, W., Rinninger, F., Radner, H., Breslow, J. L., Goldberg, I. J., Zechner, R. Greten, H. (2002) Inactive lipoprotein lipase (LPL) alone increases selective cholesterol ester uptake in vivo, whereas in presence of active LPL it also increases triglyceride hydrolysis and whole particle lipoprotein uptake. Journal of Biological Chemistry 277, 7404 7411.
27. Murase, T., Yamada, N., Akanuma, Y. Ohsawa, N. (1982) Triacylglycerol lipases in adrenals and testis of rats. Journal of Biochemistry 92, 817 821.
28. Nielsen, J. E., Hansen, M. A., Jørgensen, M., Tanaka, M., Almstrup, K., Skakkebaek, N. E. Leffers, H. (2003) Germ cell differentiation-dependent and stage-specific expression of LANCL1 in rodent testis. European Journal of Histochemistry 47, 215 222.
29. Novotny, G. W., Sonne, S. B., Nielsen, J. E., Jonstrup, S. P., Hansen, M. A., Skakkebaek, N. E., Rajpert-De Meyts, E., Kjems, J. Leffers, H. (2007) miRNA mediated translational repression of E2F1 mRNA in normal human testis and pre-invasive carcinoma in situ (CIS). Cell Death and Differentiation 14, 879 882.
30. Skakkebaek, N. E. (1972) Possible carcinoma-in-situ of the testis. Lancet 2, 516 517.
31. Skakkebaek, N. E., Berthelsen, J. G., Giwercman, A. Müller, J. (1987) Carcinoma-in-situ of the testis: possible origin from gonocytes and precursor of all types of germ cell tumours except spermatocytoma. International Journal of Andrology 10, 19 28.
32. Skotheim, R. I., Lind, G. E., Monni, O., Nesland, J. M., Abeler, V. M., Foss, S. D. et al. (2005) Differentiation of human embryonal carcinomas in vitro and in vivo reveals expression profiles relevant to normal developmen. Cancer Research 65, 5588 5598.
33. Strauss, J. G., Zimmermann, R., Hrzenjak, A., Zhou, Y., Kratky, D., Levak-Frank, S., Kostner, G. M., Zechner, R. Frank, S. (2002) Endothelial cell-derived lipase mediates uptake and binding of high-density lipoprotein (HDL) particles and the selective uptake of HDL-associated cholesterol esters independent of its enzymatic activity. Journal of Clinical Investigation 368, 69 79.
34. Travis, A. J. Kopf, G. S. (2002) The role of cholesterol efflux in regulating the fertilization potential of mammalian spermatozoa. Journal of Clinical Investigation 110, 731 736.
35. Williams, K. J., Fless, G. M., Petrie, K. A., Snyder, M. L., Brocia, R. W. Swenson, T. L. (1992) Mechanisms by which lipoprotein lipase alters cellular metabolism of lipoprotein(a), low density lipoprotein, and nascent lipoproteins. Roles for low density lipoprotein receptors and heparan sulfate proteoglycans. Journal of Biological Chemistry 267, 13284 13292.