Is a picture worth a thousand (forgotten) words?: Neuroimaging evidence for the cognitive deficits in 'chemo-fog'/'chemo-brain'

Journal of Clinical Pharmacy and Therapeutics

Volumn 35, Issue 1, 2010, Pages 1-9

  Raffa, R B ^a  

^a TEMPLE UNIVERSITY   (United States)

Author keywords

Adverse effects; Cancer chemotherapy; Chemo brain; Chemo fog; Cognition; Neuroimaging

Indexed keywords

CARBOPLATIN; CYCLOPHOSPHAMIDE; EPIRUBICIN; FLUOROURACIL; METHOTREXATE; THIOTEPA;

BRAIN MAPPING; BREAST CANCER; CANCER CHEMOTHERAPY; CANCER SURVIVOR; COGNITIVE DEFECT; FUNCTIONAL ASSESSMENT; HUMAN; NEUROIMAGING; NOTE; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; TASK PERFORMANCE;

ANIMALS; ANTINEOPLASTIC AGENTS; BRAIN; COGNITION DISORDERS; HUMANS; MAGNETIC RESONANCE IMAGING; POSITRON-EMISSION TOMOGRAPHY;

EID: 74349093062     PISSN: 02694727     EISSN: 13652710     Source Type: Journal    
DOI: 10.1111/j.1365-2710.2009.01044.x     Document Type: Note

References (33)

1. Ahles TA, Saykin AJ (2002) Breast cancer chemotherapy-related cognitive dysfunction. Clinical Breast Cancer, 3 (Suppl. 3 S84 S90.
2. Anderson-Hanley C, Sherman ML, Riggs R, Agocha VB, Compas BE (2003) Neuropsychological effects of treatments for adults with cancer: a meta-analysis and review of the literature. Journal of the International Neuropsychology Society, 9, 967 982.
3. Tannock IF, Ahles TA, Ganz PA, van Dam FS (2004) Cognitive impairment associated with chemotherapy for cancer: report of a workshop. Journal of Clinical Oncology, 22, 2233 2239.
4. Castellon SA, Silverman DHS, Ganz PA (2005) Breast cancer treatment and cognitive functioning: current status and future challenges in assessment. Breast Cancer Research and Treatment, 92, 199 206.
5. Falleti MG, Sanfilippo A, Maruff P, Weih L, Phillips KA (2005) The nature and severity of cognitive impairment associated with adjuvant chemotherapy in women with breast cancer: a meta-analysis of the current literature. Brain and Cognition, 59, 60 70.
6. Welzel G, Steinworth S, Wenz F (2005) Cognitive effects of chemotherapy andor cranial irradiatipon in adults. Strahlentherapie und Onkologie, 181, 141 156.
7. Correa DD, Ahles TA (2007) Cognitive adverse effects of chemotherapy in breast cancer patients. Current Opinion in Supportive and Palliative Care, 1, 57 62.
8. Raffa RB, Duong PV, Finney J et al. (2006) Is 'chemo-fog''chemo-brain' caused by cancer chemotherapy? Journal of Clinical Pharmacy and Therapeutics, 31, 129 138.
9. Wieneke MH, Dienst ER (1995) Neuropsychological assessment of cognitive functioning following chemotherapy for breast cancer. Psycho-Oncology, 4, 61 66.
10. van Dam FSAM, Schagen SB, Muller MJ, Boogerd W, Wall Evd, Droogleever Fortuyn ME, Rodenhuis S (1998) Impairment of cognitive function in women receiving adjuvant treatment for high-risk breast cancer: high-dose versus standard-dose chemotherapy. Journal of the National Cancer Institute, 90, 210 218.
11. Schagen SB, van Dam FSAM, Muller MJ, Boogerd W, Lindeboom J, Bruning PF (1999) Cognitive deficits after postoperative adjuvant chemotherapy for breast carcinoma. Cancer, 85, 640 650.
12. Brezden CB, Phillips K-A, Abdolell M, Bunston T, Tannock IF (2000) Cognitive function in breast cancer patients receiving adjuvant chemotherapy. Journal of Clinical Oncology, 18, 2695 2701.
13. Ahles TA, Saykin AJ, Furstenberg CT et al. (2002) Neuropsychologic impact of standard-dose systemic chemotherapy in long-term survivors of breast cancer and lymphoma. Journal of Clinical Oncology, 20, 485 493.
14. O'Shaughnessy JA (2002) Effects of epoetin alfa on cognitive function, mood, asthenia, and quality of life in women with breast cancer undergoing adjuvant chemotherapy. Clinical Breast Cancer, 3 (Suppl. 3 S116 S120.
15. Schagen SB, Muller MJ, Boogerd W, Rosenbrand RM, Rhijn D, Rodenhuis S, van Dam FS (2002) Late effects of adjuvant chemotherapy on cognitive function: a follow-up study in breast cancer patients. Annals of Oncology, 13, 1387 1397.
16. Tchen N, Juffs HG, Downie FP et al. (2003) Cognitive changes, fatigue and menopausal symptoms in women receiving adjuvant chemotherapy for breast cancer: a prospective matched cohort study. Journal of Clinical Oncology, 21, 4175 4183.
17. Ganz PA, Desmond KA, Leedham B, Rowland JH, Meyerowitz BE, Belin TR (2002) Quality of life in long-term, disease-free survivors of breast cancer: a follow-up study. Journal of the National Cancer Institute, 94, 39 49.
18. Jemal A, Siegel R, Ward E, Murray T, Xu J, Smigal C, Thun MJ (2006) Cancer statistics, 2006. CA: A Cancer Journal for Clinicians, 56, 106 130.
19. Donovan KA, Small BJ, Andrykowski MA, Schmitt FA, Munster P, Jacobsen PB (2005) Cognitive functioning after adjuvant chemotherapy andor radiotherapy for early-stage breast carcinoma. Cancer, 104, 2499 2507.
20. Matsuda T, Takayama T, Tashiro M, Nakamura Y, Ohashi Y, Shimozuma K (2005) Mild cognitive impairment after adjuvant chemotherapy in breast cancer patients - evaluation of appropriate research design and methodology to measure symptoms. Breast Cancer, 12, 279 287.
21. Jenkins V, Shilling V, Deutsch G et al. (2006) A 3-year prospective study of the effects of adjuvant treatments on cognition in women with early stage breast cancer. British Journal of Cancer, 94, 828 834.
22. Kreukels BP, Schagen SB, Ridderinkhof KR, Boogerd W, Hamburger HL, Muller MJ, van Dam FS (2005) Effects of high-dose and conventional-dose adjuvant chemotherapy on long-term cognitive sequelae in patients with breast cancer: an electrophysiologic study. Clinical Breast Cancer, 7, 67 78.
23. Kreukels BPC, Schagen SB, Ridderinkhof KR, Boogerd W, Hamburger HL, van Dam FSAM (2006) Electrophysiological correlates of information processing in breast-cancer patients treated with adjuvant chemotherapy. Breast Cancer Research and Treatment, 94, 53 61.
24. Sternberg S (1969) The discovery of processing stages: extension of Donders' method. Acta Psychologica, 30, 276 315.
25. Sanders AF (1983) Towards a model of stress and human performance. Acta Psychologica, 53, 61 97.
26. Sanders AF (1990) Issues and trends in the debate on discrete vs. continuous processing of information. Acta Psychologica, 74, 123 167.
27. Stemmer SM, Stears JC, Burton BS, Jones RB, Simon JH (1994) White matter changes in patients with breast cancer treated with high-dose chemotherapy and autologous bone marrow support. American Journal of Neuroradiology, 15, 1267 1273.
28. Brown MS, Simon JH, Stemmer SM, Stears JC, Scherzinger A, Cagnoni PJ, Jones RB (1995) MR and proton spectroscopy of white matter disease induced by high-dose chemotherapy with bone marrow transplant in advanced breast carcinoma. American Journal of Neuroradiology, 16, 2013 2020.
29. Brown MS, Stemmer SM, Simon JH, Stears JC, Jones RB, Cagnoni PJ, Sheeder JL (1998) White matter disease induced by high-dose chemotherapy: longitudinal study with MR imaging and proton spectroscopy. American Journal of Neuroradiology, 19, 217 221.
30. Yoshikawa E, Matsuoka Y, Inagaki M et al. (2005) No adverse effects of adjuvant chemotherapy on hippocampal volume in Japanese breast cancer survivors. Breast Cancer Research and Treatment, 92, 81 84.
31. Inagaki M, Yoshikawa E, Matsuoka Y et al. (2007) Smaller regional volumes of brain gray and white matter demonstrated in breast cancer survivors exposed to adjuvant chemotherapy. Cancer, 109, 146 156.
32. Ferguson RJ, McDonald BC, Saykin AJ, Ahles TA (2007) Brain structure and function differences in monozygotic twins: possible effects of breast cancer chemotherapy. Journal of Clinical Oncology, 25, 3866 3870.
33. Silverman DHS, Dy CJ, Castellon SA et al. (2007) Altered frontocortical, cerebellar, and basal ganglia activity in adjuvant-treated breast cancer survivors 5-10 years after chemotherapy. Breast Cancer Research and Treatment, 103, 303 311.