Transgenic expression of Notch in melanocytes demonstrates RBP-Jκ-dependent signaling

Pigment Cell and Melanoma Research

Volumn 23, Issue 1, 2010, Pages 134-136

  Schouwey, Karine ^a   Larue, Lionel ^b   Radtke, Freddy ^a   Delmas, Véronique ^b   Beermann, Friedrich ^a  

^a EPFL   (Switzerland)

^b INSTITUT CURIE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN J RECOMBINATION SIGNAL SEQUENCE BINDING PROTEIN; NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN 2; NOTCH RECEPTOR; NOTCH1 RECEPTOR; NOTCH2 RECEPTOR;

GENE EXPRESSION; HAIR; HAIR ROOT; IMMUNOHISTOCHEMISTRY; LETTER; MELANOCYTE; MELANOMA; MUTATION; NONHUMAN; PHENOTYPE; PIGMENTATION; STEM CELL; TRANSGENIC MOUSE; TRANSGENICS; WILD TYPE;

ANIMALS; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; GENE EXPRESSION REGULATION; HAIR; IMMUNOGLOBULIN J RECOMBINATION SIGNAL SEQUENCE-BINDING PROTEIN; MELANOCYTES; MELANOMA; MICE; MICE, TRANSGENIC; PIGMENTATION; RECEPTOR, NOTCH1; RECEPTOR, NOTCH2; SIGNAL TRANSDUCTION; SKIN NEOPLASMS; STEM CELLS;

EID: 74349092999     PISSN: 17551471     EISSN: 1755148X     Source Type: Journal    
DOI: 10.1111/j.1755-148X.2009.00651.x     Document Type: Letter

References (6)

1. Aubin-Houzelstein, G., Djian-Zaouche, J., Bernex, F., Gadin, S., Delmas, V., Larue, L. Panthier, J.J. (2008). Melanoblasts' proper location and timed differentiation depend on Notch/RBP-J signaling in postnatal hair follicles. J. Invest. Dermatol. 128, 2686 2695.
2. Hsieh, J.J., Henkel, T., Salmon, P., Robey, E., Peterson, M.G. Hayward, S.D. (1996). Truncated mammalian Notch1 activates CBF1/RBPJk-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2. Mol. Cell. Biol. 16, 952 959.
3. Kumano, K., Masuda, S., Sata, M. et al. (2008). Both Notch1 and Notch2 contribute to the regulation of melanocyte homeostasis. Pigment Cell Melanoma Res. 21, 70 78.
4. Moriyama, M. et al. (2006). Notch signaling via Hes1 transcription factor maintains survival of melanoblasts and melanocyte stem cells. J. Cell Biol. 173, 333 339.
5. Schouwey, K. Beermann, F. (2008). The Notch pathway: hair graying and pigment cell homeostasis. Histol. Histopathol. 23, 609 619.
6. Schouwey, K., Delmas, V., Larue, L., Zimber-Strobl, U., Strobl, L.J., Radtke, F. Beermann, F. (2007). Notch1 and Notch2 receptors influence progressive hair graying in a dose-dependent manner. Dev. Dyn. 236, 282 289.