The history of ergot of rye (Claviceps purpurea) II: 1900-1940

Journal of the Royal College of Physicians of Edinburgh

Volumn 39, Issue 4, 2009, Pages 365-369

  Lee, M R ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Ergometrine; Ergotamine; Ergotoxine; Henry Dale; Migraine; Postpartum haemorrhage

Indexed keywords

ACETYLCHOLINE; ADRENALIN; ADRENERGIC RECEPTOR; ANALGESIC AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CADAVERINE; ERGOCORNINE; ERGOCRISTINE; ERGOCRYPTINE; ERGOMETRINE; ERGOTAMINE; ERGOTOXINE; HISTAMINE; IBUPROFEN; METHYLERGOMETRINE; NITROPRUSSIDE SODIUM; ORAL CONTRACEPTIVE AGENT; PUTRESCINE; SEROTONIN RECEPTOR; SPERMINE; SUMATRIPTAN; TRIPTAN DERIVATIVE; TYRAMINE;

ABORTION; ADRENAL GLAND; ANGINA PECTORIS; BLOOD PRESSURE; CHEMISTRY; CHEMORECEPTOR; CLAVICEPS PURPUREA; DRUG BINDING; DRUG CLEARANCE; DRUG EFFICACY; DRUG HALF LIFE; DRUG MEGADOSE; DRUG OVERDOSE; DRUG SAFETY; DRUG STRUCTURE; ERGOTISM; FETUS DEATH; FIBROSIS; HEART INFARCTION; HEART VALVE FIBROSIS; HUMAN; LOW DRUG DOSE; MEDIASTINUM FIBROSIS; MEDULLA OBLONGATA; MIGRAINE; MIGRAINE WITH AURA; NECROSIS; PERITONEUM FIBROSIS; POLAND SYNDROME; POSTPARTUM HEMORRHAGE; PREGNANCY; PROLACTIN BLOOD LEVEL; REVIEW; RYE; SCIENTIST; SIDE EFFECT; UTERUS CONTRACTION; VOMITING;

CHEMISTRY; ENGLAND; ERGONOVINE; ERGOT ALKALOIDS; ERGOTAMINE; HISTORY, 20TH CENTURY; HUMANS; PHYSIOLOGY;

EID: 74249123613     PISSN: 14782715     EISSN: None     Source Type: Journal    
DOI: 10.4997/JRCPE.2009.416     Document Type: Review

References (24)

1. Dale HH. Les Prix Nobel in 1936. Stockholm: Nobel Foundation; 1937. p. 91-2.
2. Feldberg WS. Henry Hallett Dale, 1875-1968. Biogr Mem Fellows R Soc 1970; 16:77-174. doi:10.1098/rsbm.1970.0006
3. Barger G, Dale HH. Ergotoxine and some other constituents of ergot. Biochem J 1907; 2:240-99.
4. Barger G. Ergot and ergotism. London: Gurney and Jackson; 1931.
5. Harington CR, Barger G. Chemistry of thyroxine III: constitution and synthesis of thyroxine. Biochem J 1927; 21:169-74.
6. Stoll A, Hofmann A. Partialsynthese von Alkaloiden vom Typus des Ergobasins. Helv Chim Acta 1943; 26:944-65. doi:10.1002/ hlca.19430260326
7. Stoll A. Zur Kenntnis der Mutterkornalkaloide. Verh Schweiz Naturf Ges 1918; 101:190-1.
8. Stoll A, Hofmann A, Petrzilka T. Die Konstitution der Mutterkornalkaloide. Struktur des Peptidteils. III. Helv Chim Acta 1951; 34:1544-76. doi:10.1002/hlca.19510340539
9. Silberstein SD, Lipton RB, Dalessio DJ, editors. Wolff 's headache and other head pain. 7th ed. New York: Oxford University Press; 2001. p. 121-237.
10. Graham JR, Wolff HG. Mechanisms of migraine headache and action of ergotamine tartrate. Arch Neurol Psychiatr 1938; 39:737-63.
11. Dollery CT, editor. Ergotamine. In: Therapeutic drugs. Vol. I. Edinburgh: Churchill Livingstone; 1991. E42-E45.
12. Müller-Schweinitzer E, Weidmann H. Regional differences in the responsiveness of isolated arteries from cattle, dog and man. Agents Actions 1977; 7:383-9. doi:10.1007/BF01969572
13. Tfelt-Hansen P, Paalzow L. Intramuscular ergotamine: plasma levels and dynamic activity. Clin Pharmacol Ther 1985; 37:29-35.
14. Joint Formulary Committee. British National Formulary. 53rd ed. London: British Medical Association and Royal Pharmaceutical Society of Great Britain; 2007. p. 237-9.
15. Berde B, Schild HO, editors. Ergot alkaloids and related compounds. Berlin, Heidelberg, New York: Springer; 1978.
16. Lee MR. The history of ergot of rye (Claviceps purpurea) I: from antiquity to 1900. J R Coll Physicians Edinb 2009; 39:179-84.
17. Moir JC, Dale HH. The action of ergot preparations on the puerperal uterus. Br Med J 1932; 1:1119-22. doi:10.1136/ bmj.1.3728.1119
18. Dunn PM. John Chassar Moir (1900-1977) and the discovery of ergometrine. Arch Dis Child Fetal Neonatal Ed 2002; 87:F152-4. doi:10.1136/fn.87.2. F152
19. Dudley HW, Moir JC. The substance responsible for the traditional clinical effect of ergot. BMJ 1935; 1:520-3. doi:10.1136/ bmj.1.3871.520
20. Dudley HW. Ergometrine. Proc R Soc Lond 1935; 118:478-84. doi:10.1098/rspb.1935.0067
21. Dale HH. Dudley, Harold Ward. Obit Not Fell R Soc 1935; 1:595-606.
22. Dollery CT, editor. Ergometrine. In: Therapeutic drugs. Vol. I. Edinburgh: Churchill Livingstone; 1991. E38-E41.
23. Lee MR. The history of ergot of rye (Claviceps purpurea) III: 1940-1980. J R Coll Physicians Edinb 2010; in press.
24. Dale HH. Barger, George. Obit Not Fell R Soc 1941; 3: 63-85.