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Volumn 24, Issue 1, 2010, Pages 216-219

TP53 mutations in myeloid malignancies are either homozygous or hemizygous due to copy number-neutral loss of heterozygosity or deletion of 17p

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

EID: 74249120916     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2009.189     Document Type: Letter
Times cited : (69)

References (8)
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    • MacIejewski, J.P.1    Mufti, G.J.2
  • 2
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    • Myelodysplastic syndromes and acute myeloid leukemia with 17p deletion. An entity characterized by specific dysgranulopoiesis and a high incidence of P53 mutations
    • Lai JL, Preudhomme C, Zandecki M, Flactif M, Vanrumbeke M, Lepelley P et al. Myelodysplastic syndromes and acute myeloid leukemia with 17p deletion. An entity characterized by specific dysgranulopoiesis and a high incidence of P53 mutations. Leukemia 1995; 9: 370-381.
    • (1995) Leukemia , vol.9 , pp. 370-381
    • Lai, J.L.1    Preudhomme, C.2    Zandecki, M.3    Flactif, M.4    Vanrumbeke, M.5    Lepelley, P.6
  • 3
    • 34248379012 scopus 로고    scopus 로고
    • Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: Lessons from recent developments in the IARC TP53 database
    • Petitjean A, Mathe E, Kato S, Ishioka C, Tavtigian SV, Hainaut P et al. Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database. Hum Mutat 2007; 28: 622-629.
    • (2007) Hum Mutat , vol.28 , pp. 622-629
    • Petitjean, A.1    Mathe, E.2    Kato, S.3    Ishioka, C.4    Tavtigian, S.V.5    Hainaut, P.6
  • 4
    • 0035004853 scopus 로고    scopus 로고
    • Loss of heterozygosity or intragenic mutation, which comes first?
    • Wilentz RE, Argani P, Hruban RH. Loss of heterozygosity or intragenic mutation, which comes first? Am J Pathol 2001; 158: 1561-1563.
    • (2001) Am J Pathol , vol.158 , pp. 1561-1563
    • Wilentz, R.E.1    Argani, P.2    Hruban, R.H.3
  • 5
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    • Mutations with loss of heterozygosity of p53 are common in therapy-related myelodysplasia and acute myeloid leukemia after exposure to alkylating agents and significantly associated with deletion or loss of 5q, a complex karyotype, and a poor prognosis
    • Christiansen DH, Andersen MK, Pedersen-Bjergaard J. Mutations with loss of heterozygosity of p53 are common in therapy-related myelodysplasia and acute myeloid leukemia after exposure to alkylating agents and significantly associated with deletion or loss of 5q, a complex karyotype, and a poor prognosis. J Clin Oncol 2001; 19: 1405-1413.
    • (2001) J Clin Oncol , vol.19 , pp. 1405-1413
    • Christiansen, D.H.1    Andersen, M.K.2    Pedersen-Bjergaard, J.3
  • 6
    • 58249122390 scopus 로고    scopus 로고
    • TP53 gene mutation is frequent in patients with acute myeloid leukemia and complex karyotype, and is associated with very poor prognosis
    • Bowen D, Groves MJ, Burnett AK, Patel Y, Allen C, Green C et al. TP53 gene mutation is frequent in patients with acute myeloid leukemia and complex karyotype, and is associated with very poor prognosis. Leukemia 2009; 23: 203-206.
    • (2009) Leukemia , vol.23 , pp. 203-206
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    • Mutations of the TP53 gene in acute myeloid leukemia are strongly associated with a complex aberrant karyotype
    • Haferlach C, Dicker F, Herholz H, Schnittger S, Kern W, Haferlach T. Mutations of the TP53 gene in acute myeloid leukemia are strongly associated with a complex aberrant karyotype. Leukemia 2008; 22: 1539-1541.
    • (2008) Leukemia , vol.22 , pp. 1539-1541
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.