A validated stability-indicating LC method for acetazolamide in the presence of degradation products and its process-related impurities

Journal of Pharmaceutical and Biomedical Analysis

Volumn 52, Issue 1, 2010, Pages 142-148

  Srinivasu, Prabha ^a,b   SubbaRao, Devarakonda V ^a   Vegesna, Raju V K ^a   Sudhakar Babu, K ^b  

^a Versapharm Incorporated   (United States)

^b SRI KRISHNADEVARAYA UNIVERSITY   (India)

Author keywords

Acetazolamide; Forced degradation; LC MS; RP LC; Stability indicating; Validation

Indexed keywords

ACETAZOLAMIDE; N (5 CHLORO 1,3,4 THIADIAZOLE 2 YL)ACETAMIDE; N (5 MERCAPTO 1,3,4 THIADIAZOL 2 YL)ACETAMIDE; N (5 SULFAMOYL 1,3,4 THIADIAZOL 2 YL)ACETAMIDE; N (5 SULFAMOYL 1,3,4 THIADIAZOL 2 YL)AMINE; N,N' (DITHIODI 1,3,4 THIADIAZOLE 5,2 DIYL)DIACETAMIDE; N,N' [IMINOBIS(SULFONYL 1,3,4 THIADIAZOLE 5,2 DIYL)]DIACETAMIDE; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DEGRADATION KINETICS; DRUG DETERMINATION; DRUG IMPURITY; DRUG QUALITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; INFRARED SPECTROSCOPY; MASS SPECTROMETRY; OXIDATION; PHOTOLYSIS; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE ANALYSIS; REVERSED PHASE LIQUID CHROMATOGRAPHY; SENSITIVITY AND SPECIFICITY;

ACETAZOLAMIDE; BUFFERS; CARBONIC ANHYDRASE INHIBITORS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, REVERSE-PHASE; DRUG CONTAMINATION; DRUG STABILITY; GUIDELINES AS TOPIC; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; OXIDATION-REDUCTION; PHOTOLYSIS; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TECHNOLOGY, PHARMACEUTICAL; TEMPERATURE;

EID: 74249118295     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2009.12.011     Document Type: Article

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